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Meds 700 Medicinal Uses for Cannabis sorted by Disease

momofthegoons

Vapor Accessory Addict
Staff member
Pages 101 - 105

Evidence for the presence of cannabinoid CB1 receptors in mouse urinary bladder (abst – 1996) http://pharmgkb.org/pmid/8864542

Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1571997/?tool=pmcentrez

Clinical investigation of delta-9-tetrahydrocannabinol (THC) as an alternative therapy for overactive bladders in spinal cord injury (SCI) patients. (abst - 2001) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=102

Contrasting effects of WIN 55212-2 on motility of the rat bladder and uterus. (full – 2002) http://www.jneurosci.org/content/22/16/7147.long

An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis. (full - 2004) http://www.ukcia.org/research/CBEForMSBladderDysfunction.pdf

Therapy Insight: Bladder Dysfunction Associated With Multiple Sclerosis (full - 2005)

http://www.medscape.com/viewarticle/515091

Marijuana-Derived Drug Suppresses Bladder Overactivity And Irritation In Animal Models (news - 2005) http://www.sciencedaily.com/releases/2005/09/050906080225.htmhttp://www.sciencedaily.com/releases/2 005/09/050906080225.htm

Marijuana-Derived Drug Suppresses Bladder Pain In Animal Models (news - 2006)

http://www.sciencedaily.com/releases/2006/05/060521103039.htm

Effects of IP-751, ajulemic acid, on bladder overactivity induced by bladder irritation in rats. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17656248

Cannabinoid receptor 2 is increased in acutely and chronically inflamed bladder of rats (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592089/?tool=pmcentrez

Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19237169

Incontinence (news - 2009) http://www.norml.org/index.cfm?Group_ID=7012

Functional role of cannabinoid receptors in urinary bladder (full - 2010)

http://www.indianjurol.com/article.asp?issn=0970- 1591;year=2010;volume=26;issue=1;spage=26;epage=35;aulast=Tyagi

Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction. (abst – 2010) http://www.unboundmedicine.com/medline/ebm/record/21168864/abstract/Cannabinor_a_selective_cannab inoid_2_receptor_agonist_improves_bladder_emptying_in_rats_with_partial_urethral_obstruction_

101

Effects of cannabinor, a novel selective cannabinoid 2 receptor agonist, on bladder function in normal rats. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20207474

Randomized controlled trial of Sativex to treat detrusor overactivity in multiple sclerosis. (abst – 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=314

Local activation of cannabinoid CB1 receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents. (full – 2011) http://www.molecularpain.com/content/pdf/1744-8069-7-31.pdf

Inhibitory Effect of Standardized Cannabis sativa Extract and Its Ingredient Cannabidiol on Rat and Human Bladder Contractility. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21310467

Cannabinoids: potential targets for bladder dysfunction. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21290238

Cannabinoid mediated diuresis in mice (abst – 2011)

http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/617.6?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype =HWCIT

BLEPHAROSPASM - also see MEIGE'S SYNDROME
Open label evaluation of cannabidiol in dystonic movement disorders. (full - 1986)

http://web.acsalaska.net/~warmgun/es017.html

Cannabinoid agonists in the treatment of blepharospasm--a case report study. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15159681

BLOOD

The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation. (abst - 1989) http://www.ncbi.nlm.nih.gov/pubmed/2575149

Estrogen stimulates arachidonoylethanolamide release from human endothelial cells and

platelet activation (full – 2002)

http://bloodjournal.hematologylibrary.org/content/100/12/4040.full

102

The Procoagulatory Effects of Delta-9-Tetrahydrocannabinol in Human Platelets
(full - 2004)
http://www.anesthesia- analgesia.org/content/99/4/1127.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid& searchid=1&FIRSTINDEX=1280&resourcetype=HWCIT

Plasma Levels of the Endocannabinoid Anandamide in Women—A Potential Role in Pregnancy Maintenance and Labor? (full - 2004) http://jcem.endojournals.org/cgi/content/full/89/11/5482?ijkey=5e8ec5690352ba9f6b990355b2ed69b1d2e5 8a5b

Anticoagulant Effects of a Cannabis Extract in an Obese Rat Model (abst - 2007)

http://marijuana.researchtoday.net/archive/4/4/736.htm

Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseed- enriched diet. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18418423

Circulating endocannabinoid concentrations during orthostatic stress (abst – 2009)

www.ncbi.nlm.nih.gov/pubmed/19756829

Anandamide extends platelets survival through CB(1)-dependent Akt signaling. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/19936621

Effect of Cannabis sativa on Hematological Indices in Rats and Men (full – 2011)

http://docsdrive.com/pdfs/ansinet/pjn/2011/313-316.pdf

BLOOD PRESSURE

Reduction by Δ9-tetrahydrocannabinol in the blood pressure of hypertensive rats bearing regenerated adrenal glands (full - 1973) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1776093/?page=1

Cannabinoids. II. Cardiovascular Effects (full - 1980)

http://jpet.aspetjournals.org/content/214/1/131.full.pdf+html?ijkey=e751d405c4b7e494c235b602119e4f9b 8c62c04d&keytype2=tf_ipsecsha

Effect of marihuana on intraocular and blood pressure in glaucoma (full - 1980)

http://www.ukcia.org/research/EffectOnIntraocularAndBloodPressureInGlaucoma.php

The cardiovascular and autonomic effects of repeated administration of delta-9- tetrahydrocannabinol to rhesus monkeys. (abst – 1981) http://www.ncbi.nlm.nih.gov/pubmed/6257883

Glaucoma, hypertension, and marijuana. (full - 1982)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2552967/?tool=pmcentrez&page=1

103

Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin (abst - 1995) http://ajpheart.physiology.org/cgi/content/abstract/269/6/H1859?maxtoshow=&hits=80&RESULTFORMA T=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=2320&resourcetype=HWCIT

Cannabinoid-Induced Hypotension and Bradycardia in Rats Is Mediated by CB1-Like Cannabinoid Receptors (full - 1997) http://jpet.aspetjournals.org/content/281/3/1030.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT

Body's 'cannabis' could hold blood pressure key (news - 1998)

http://www.ukcia.org/research/blood-pressure.php

Endocannabinoids and Vascular Function (full - 2000)

http://jpet.aspetjournals.org/content/294/1/27.long

Endogenous cannabinoids mediate hypotension after experimental myocardial infarction (full - 2001) http://content.onlinejacc.org/cgi/content/full/38/7/2048?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT

Cardiovascular Effects of Cannabis (news- 2003) http://www.idmu.co.uk/canncardio.htm

Endocannabinoids Acting at Cannabinoid-1 Receptors Regulate Cardiovascular Function in Hypertension (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756479/?tool=pmcentrez

Blood pressure regulation by endocannabinoids and their receptors

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225528/?tool=pmcentrez

Cardiovascular Pharmacology of Cannabinoids (full - 2005)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228270/?tool=pmcentrez

(full - 2005)

Influence of Anandamide, the Endogenous Agonist of Cannabinoid Receptors on the Circulatory System (abst - 2005) http://medical-journals.healia.com/doc/15928605/Influence-of-anandamide-the-endogenous-agonist-of- cannabinoid-receptors-on-the-circulatory-system

Further Characterization of the Time-Dependent Vascular Effects of Δ9- Tetrahydrocannabinol (full - 2006) http://jpet.aspetjournals.org/content/317/1/428.full

The Cannabinoid Cb1 Receptor Antagonist Rimonabant Attenuates the Hypotensive Effect of Smoked Marijuana in Male Smokers. (full – 2006) http://www.ahjonline.com/article/S0002-8703(05)01013-6/fulltext

Lowering Of Blood Pressure Achieved Through Use Of Hashish-Like Drug (news - 2006) http://www.sciencedaily.com/releases/2006/06/060620083025.htm

104

Cannabis to lower blood pressure! (news - 2006)

http://www.news-medical.net/news/2006/06/19/18517.aspx

Marijuana may be Helpful in Lowering Blood Pressure (news – 2006)

http://www.bio-medicine.org/medicine-news/Marijuana-may-be-Helpful-in-Lowering-Blood-Pressure- 11460-1/

The in vitro and in vivo cardiovascular effects of {Delta}9-tetrahydrocannabinol (THC) in rats made hypertensive by chronic inhibition of nitric oxide synthase. (full - 2007) http://jpet.aspetjournals.org/content/321/2/663.full

Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta (full – 2007)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190007/?tool=pubmed

Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190006/?tool=pmcentrez

2-Arachidonylglyceryl ether and abnormal cannabidiol-induced vascular smooth muscle relaxation in rabbit pulmonary arteries via receptor-pertussis toxin sensitive G proteins- ERK1/2 signaling. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/17292352

Endocannabinoids, blood pressure and the human heart. (full - 2008).

http://www3.interscience.wiley.com/cgi-bin/fulltext/119409853/HTMLSTART

Modulation of the Endocannabinoid System in Cardiovascular Disease (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568884/?tool=pmcentrez

Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697765/?tool=pmcentrez

Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22022923

Increased Blood Pressure Following Abrupt Cessation of Daily Cannabis Use. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21359104

Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238581

Low-volume binary drug therapy for the treatment of hypovolemia. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21330941

BONES - see OSTEOPOROSIS

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Last edited:

momofthegoons

Vapor Accessory Addict
Staff member
Pages 106 - 110

BONE MARROW

Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/17205329

Endocannabinoids Are Expressed in Bone Marrow Stromal Niches and Play a Role in Interactions of Hematopoietic Stem and Progenitor Cells with the Bone Marrow Microenvironment (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975171/?tool=pubmed

Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109635/?tool=pubmed

Regulation of hematopoietic stem cell trafficking and mobilization by the endocannabinoid system. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22074629

Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21063029

BOWEL DISORDERS - also see GERD, COLITIS,
MARIJUANA AND IRRITABLE BOWEL SYNDROME (IBS)

(anecdotal- no date) http://www.rxmarihuana.com/christine.htm
Effects of cannabidiol derivatives on intestinal motility (abst - no date)

http://www.docstoc.com/docs/26071658/Effects-of-cannabidiol-derivatives-on-intestinal-motility-

Some actions of delta-1 tetrahydrocannabinol and cannabidiol at cholinergic junctions. (full – 1971) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1703324/pdf/brjpharm00552-0217.pdf

The effect of cannabinoids on intestinal motility and their antinociceptive effect in mice (full - 1973) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1776598/?tool=pmcentrez&page=1

Intestinal obstruction by an unusual foreign body (full - 1973)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1946817&tool=pmcentrez

Psychoactive Cannabinoids Reduce Gastrointestinal Propulsion and Motility in Rodents (full - 1989) http://jpet.aspetjournals.org/content/249/2/444.full.pdf+html

Marijuana and Crohn‘s Disease (anecdotal - 1997)

http://www.rxmarihuana.com/chrohns3.htm
106

Inhibitory effect of cannabinoid agonists on gastric emptying in the rat (abst – 1999)

http://www.springerlink.com/content/8fe31unaaat4fbd4/

The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats (abst - 1999) http://www.ncbi.nlm.nih.gov/pubmed/10611417

Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oil (full - 2000) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1572019&tool=pmcentrez

Modulation of peristalsis by cannabinoid CB1 ligands in the isolated guinea-pig ileum (full - 2000) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1571902&tool=pmcentrez

Inhibition of small intestinal secretion by cannabinoids is CB1 receptor-mediated in rats (abst – 2000) http://www.sciencedirect.com/science/article/pii/S0014299900008438

Cannabinoid CB1-mediated inhibition of stress-induced gastric ulcers in rats (abst – 2000) http://www.springerlink.com/content/w3jc8rk16k9p92fl/

Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572987/?tool=pmcentrez

Cannabinoids and the gastrointestinal tract (full - 2001)

http://gut.bmj.com/content/48/6/859.full

Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon (full – 2003) http://ajpgi.physiology.org/content/286/1/G110.full?sid=fc6948f0-78cf-405c-981b-afaa05ee417c

Cannabinoids for gastrointestinal diseases: potential therapeutic applications (abst - 2003) http://informahealthcare.com/doi/abs/10.1517/13543784.12.1.39

Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. (full - 2004) http://ajpgi.physiology.org/cgi/content/full/287/1/G7

Cannabinoids and intestinal motility: welcome to CB2 receptors (full - 2004)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575197/

Involvement of cannabinoid receptors in gut motility and visceral perception. (full – 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574910/?tool=pubmed

(full – 2002) Endocannabinoids as physiological regulators of colonic propulsion in mice.

Patent 6410588 Use of cannabinoids as anti-inflammatory agents

http://www.patentstorm.us/patents/6410588/fulltext.html
(abst – 2002) http://www.ncbi.nlm.nih.gov/pubmed/12105851
107

Effect of ethanol extracts of three Chinese medicinal plants with laxative properties on ion transport of the rat intestinal epithelia. (full - 2004) http://www.jstage.jst.go.jp/article/bpb/27/2/162/_pdf

The endogenous cannabinoid system protects against colonic inflammation
(full - 2004) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=385396&tool=pmcentrez

Cannabinoids cool the intestine (full - 2004)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516444/?tool=pmcentrez

Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated rats (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575196/?tool=pmcentrez

Involvement of cannabinoid receptors in gut motility and visceral perception (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574910/?tool=pmcentrez

Fibromyalgia, IBS, and the Endocannabinoid-CB-Receptor (ECBR) system (abst - 2004) http://www.prohealth.com//library/showArticle.cfm?libid=10562

Cannabinoids spell relief in colon inflammation (news – 2004)

http://www.medicalnewstoday.com/releases/8069.php

The effects of Δ9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576168/?tool=pmcentrez

Effects of cannabinoids on colonic muscle contractility and tension in guinea pigs. (full – 2005) http://www.jstage.jst.go.jp/article/jnms/72/1/72_43/_article

Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1856307/?tool=pmcentrez

Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/15910887

Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing (abst - 2005) http://www.gastrojournal.org/article/PIIS0016508505009297/abstract

Cannabis drugs may benefit those with bowel disease (news - 2005)

http://www.news-medical.net/news/2005/08/01/12142.aspx

Cannabis & inflamed bowel disease (news - 2005)

http://medicalcannabisawareness.myblogsite.com/entry31.html#body
108

Cannabis-based drugs could offer new hope for inflammatory bowel disease patients (news - 2005) http://www.medicalnewstoday.com/articles/28584.php

Cannabis may soothe inflamed bowels (news - 2005)

http://www.chanvre-info.ch/info/en/Cannabis-may-soothe-inflamed.html

Cannabis Alleviates Symptoms of Crohn's Disease (news - 2005)

http://ccrmg.org/journal/05aut/chrons.html

Crohn's Patients Report Symptomatic Relief From Cannabis (news - 2005)

http://www.thehempire.com/index.php/cannabis/news/4650

Bowel Study Backs Cannabis Drugs (news - 2005)

http://www.thehempire.com/index.php/cannabis/news/bowel_study_backs_cannabis_drugs

Potential new target for cannabis-derived drugs as a treatment of inflammatory bowel disease (news - 2005) http://www.news-medical.net/news/2005/08/02/12175.aspx

Inflammatory Bowel Disease May Respond To Cannabis-Derived Drugs (news - 2005)

http://www.medpagetoday.com/Gastroenterology/InflammatoryBowelDisease/1548

Cannabis-Based Drugs Could Aid in Treating Bowel Disease (news - 2005)

http://www.drugfree.org/join-together/drugs/cannabis-based-drugs-could-in

Cannabinoid 1 (CB1) receptors coupled to cholinergic motorneurones inhibit neurogenic circular muscle contractility in the human colon. (full – 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617060/?tool=pubmed

Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P. (full – 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1856307/?tool=pubmed

Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. (full – 2006) http://www.fasebj.org/content/early/2006/03/01/fj.05-4943fje.long

Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P (full – 2006) http://gut.bmj.com/content/55/7/946.full

Endocannabinoid overactivity and intestinal inflammation (full - 2006)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1856409/?tool=pmcentrez

Effects of Cannabinoids on Colonic Muscle Contractility and Tension in Guinea Pigs (full - 2006) http://www.jstage.jst.go.jp/article/jnms/72/1/43/_pdf

Endocannabinoids and the gastrointestinal tract. (abst - 2006)

http://www.ncbi.nlm.nih.gov/pubmed/16751708?dopt=Abstract
109

Cannabinoids promote survival of normal human colonic epithelial cells (#334) (abst - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1859999/?tool=pmcentrez

Effect of a cannabinoid agonist on gastrointestinal transit and postprandial satiation in healthy human subjects: a randomized, placebo-controlled study (abst - 2006) http://cel.isiknowledge.com/InboundService.do?product=CEL&action=retrieve&SrcApp=Highwire&UT=0 00239661000005&SID=2BiIeEJCIN8n7IfjpEB&Init=Yes&SrcAuth=Highwire&mode=FullRecord&custo mersID=Highwire

Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16506408

Science: Cannabinoids reduce inflammation of the bowel in animal model

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=216#1

Synthetic THC Eases Stomach Cramping, Study Says (news - 2006)

http://www.norml.org/index.cfm?Group_ID=7080&wtm_format=print

ACG: Cannabinoid Activator Mellows Out Colon (news - 2006)

http://www.medpagetoday.com/MeetingCoverage/ACG/4410

Cannabis Helps Ulcers And Crohn's Disease (news - 2006)

(news - 2006)

http://www.thehempire.com/index.php/cannabis/news/cannabis_helps_ulcers_and_crohns_disease

Cannabis Drugs "May control Symptoms of Gut Disease‖ (news - 2006)

http://www.bloomsburycommunications.com/presscentrepdf/bsg_22_03_06_cannabis.pdf

Cannabis Chemicals May Alleviate Post-Eating Stomach Cramps (news – 2006)

http://www.bio-medicine.org/medicine-news/Cannabis-Chemicals-May-Alleviate-Post-Eating-Stomach- Cramps-15219-1/

Endocannabinoids and the gastrointestinal tract: what are the key questions? (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190011/?tool=pmcentrez

Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. (full – 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755791/?tool=pubmed

The endogenous cannabinoid system: a new player in the brain-gut-adipose axis (full - 2007) http://www.cannabis-med.org/english/journal/en_2007_02_1.pdf

Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation (full - 2007) http://ajpgi.physiology.org/cgi/content/full/294/1/G13?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=1120&resourcetype=HWCIT

Effects of a cannabinoid receptor agonist on colonic motor and sensory functions in

humans: a randomized, placebo-controlled study (full - 2007)

http://ajpgi.physiology.org/cgi/content/full/293/1/G137
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 111 - 115

Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219529/?tool=pmcentrez

Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/17396241

The endocannabinoids anandamide and 2-arachidonoylglycerol inhibit cholinergic contractility in the human colon. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/17706636

Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494728/?tool=pubmed

Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation. (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219529/?tool=pubmed

Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation (full – 2008) http://ajpgi.physiology.org/content/294/1/G13.full

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full – 2008) http://gut.bmj.com/content/57/8/1140.full

Effect of Δ9-tetrahydrocannabinol, a cannabinoid receptor agonist, on the triggering of transient lower oesophageal sphincter relaxations in dogs and humans (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697772/?tool=pmcentrez

Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2451037/?tool=pmcentrez

Cannabinoid CB1 Receptors Are Expressed by Parietal Cells of the Human Gastric Mucosa (full – 2008) http://jhc.sagepub.com/content/56/5/511.full

The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet. (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275439/?tool=pubmed

Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation. (full – 2008) http://ajpgi.physiology.org/content/294/1/G13.long

Anti-inflammatory cannabinoids in diet (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633791/?tool=pmcentrez

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (abst - 2008) http://gut.bmj.com/content/57/8/1140.abstract
111

Cannabinoids and gastrointestinal motility: animal and human studies. (abst - 2008)

http://www.unboundmedicine.com/medline/ebm/record/18924447/full_citation/Cannabinoids_and_gastroin testinal_motility:_animal_and_human_studies_

The role of the endocannabinoid system in the pathophysiology and treatment of irritable bowel syndrome. (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/18710476

Gastrointestinal endocannabinoid system: multifaceted roles in the healthy and inflamed intestine (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/18671715

Anti-inflammatory compound from cannabis found in herbs (news - 2008)

http://www.rsc.org/chemistryworld/News/2008/June/24060801.asp

Science: THC reduces reflux of acid from the stomach (news – 2008)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=285#1

How Cannabis Compares to other treatments (news - 2008)

http://dcsafeaccess.org/medical/how-cannabis-compares-to-other-treatments/

Cannabinoid-1 (CB1) receptors regulate colonic propulsion by acting at motor neurons within the ascending motor pathways in mouse colon (full - 2009) http://ajpgi.physiology.org/cgi/content/full/296/1/G119?maxtoshow=&hits=80&RESULTFORMAT=&full text=cannabinoid&searchid=1&FIRSTINDEX=160&resourcetype=HWCIT

Interaction between cannabinoid CB1 receptors and endogenous ATP in the control of spontaneous mechanical activity in mouse ileum. (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795265/?tool=pubmed

Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739820/?tool=pubmed

Endocannabinoids and the gastrointestinal tract: what are the key questions? (full - 2009) http://www3.interscience.wiley.com/cgi-bin/fulltext/121667871/HTMLSTART

Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765124/?tool=pubmed

Cannabinoids as novel anti-inflammatory drugs. (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/?tool=pubmed

Involvement of nitric oxide in the gastroprotective effect of ACEA, a selective cannabinoid CB1 receptor agonist, on aspirin-induced gastric ulceration. (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19827302

Cannabinoids in intestinal inflammation and cancer. (abst - 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19442536?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa nel.Pubmed_RVDocSum&ordinalpos=22
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Cannabis for Ulcerative Colitis and Crohn's Disease treatment (news - 2009)

http://www.news-medical.net/news/20091217/Cannabis-for-Ulcerative-Colitis-and-Crohns-Disease- treatment.aspx

Cannabis Hope for Inflammatory Bowel Disease (news - 2009)

http://www.sciencedaily.com/releases/2009/12/091220175502.htm

Gastrointestinal Disorders (news - 2009)

http://www.norml.org/index.cfm?Group_ID=7009

The Cannabinoid 1 Receptor (CNR1) 1359 G/A Polymorphism Modulates Susceptibility to Ulcerative Colitis and the Phenotype in Crohn's Disease (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829088/?tool=pmcentrez

The endocannabinoid system links gut microbiota to adipogenesis (full - 2010)

http://www.nature.com/msb/journal/v6/n1/full/msb201046.html

Involvement of cannabinoid-1 and cannabinoid-2 receptors in septic ileus. (full – 2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2009.01419.x/pdf

US Patent Application 20100222437 - COMPOSITION CONTAINING NON- PSYCHOTROPIC CANNABINOIDS FOR THE TREATMENT OF INFLAMMATORY DISEASES (full – 2010) http://www.patentstorm.us/applications/20100222437/fulltext.html

Cannabinoids and the gut: New developments and emerging concepts. (abst - 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20117132

Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20592049

Gut feelings about the endocannabinoid system (full – 2011)

http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2011.01689.x/full

Treatment of Crohn's disease with cannabis: an observational study. (full – 2011)

http://www.ima.org.il/imaj/ar11aug-01.pdf

Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232190/?tool=pubmed

Efficacy of a Chinese herbal proprietary medicine (Hemp Seed Pill) for functional constipation. (full – 2011) http://www.nature.com/ajg/journal/v106/n1/pdf/ajg2010305a.pdf

Cannabis use amongst patients with inflammatory bowel disease. (abt – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21795981
113

Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21551239/abstract/Increasing_endogenous_2_arac hidonoylglycerol_levels_counteracts_colitis_and_related_systemic_inflammation_

Role of cannabinoid receptors and RAGE in inflammatory bowel disease. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21472688/abstract/Role_of_cannabinoid_receptors _and_RAGE_in_inflammatory_bowel_disease_

The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21471961/abstract/The_endogenous_cannabinoid_ system_in_the_gut_of_patients_with_inflammatory_bowel_disease_

Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients with Non-Constipated Irritable Bowel Syndrome. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21803011

A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355

Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726418

Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21876860

The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21975813/abstract/The_effects_of_cannabidiolic_a cid_and_cannabidiol_on_contractility_of_the_gastrointestinal_tract_of_Suncus_murinus_

ENDOGENOUS CANNABINOID SYSTEM REGULATES INTESTINAL BARRIER

FUNCTION IN VIVO THROUGH CANNABINOID TYPE 1 RECEPTOR

ACTIVATION (abst – 2011)

http://ajpgi.physiology.org/content/early/2011/11/28/ajpgi.00158.2011.abstract?sid=d420a7ad-54ba-4946- b1da-8bfe664eeec2

Effects of Cannabinoid Agonists on Sheep Sphincter of Oddi in vitro. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21921665

Inhibition of cannabinoid metabolic enzymes reduces NSAID-induced gastric pathology (abst – 2011) http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/807.1?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype =HWCIT
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Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21745190

Science: Treatment of Crohn's disease with cannabis: an observational study (news – 2011) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=357#1

Surgery REVERSED by Cannabis Oil from vaporizer! (anecdotal – 2011)

http://medicalmarijuana411.com/mmj411_v3/?p=10687

―THC Oil Is Saving The Life of My Sister‖ (anecdotal – 2011)

http://medicalmarijuana411.com/mmj411_v3/?p=10599

BRAIN CELLS - see NEURONS

BRAIN - MENTAL EFFECTS - see IQ/COGNITIVE EFFECTS/ MEMORY

BRAIN - PHYSICAL EFFECTS

Absence of Cerebral Atrophy in Chronic Cannabis Users. Evaluation by Computerized Transaxial Tomography. (abst – 1977) http://medical-journals.healia.com/doc/576460/Absence-of-cerebral-atrophy-in-chronic-cannabis-users.- Evaluation-by-computerized-transaxial-tomography

Computed tomographic examination of heavy marijuana smokers. (abst – 1977)

http://www.ncbi.nlm.nih.gov/pubmed/576461

Neurological and neuroradiological examination of chronic cannabis smokers. (abst – 1983) http://www.ncbi.nlm.nih.gov/pubmed/6830182

Chronic Exposure to Delta 9-tetrahydrocannabinol Fails to Irreversibly Alter Brain Cannabinoid Receptors. (abst - 1991) http://medical-journals.healia.com/doc/1649662/Chronic-exposure-to-delta-9-tetrahydrocannabinol-fails- to-irreversibly-alter-brain-cannabinoid-receptors

Changes in cannabinoid receptor binding and mRNA levels in several brain regions of aged rats. (abst – 1998) http://www.ncbi.nlm.nih.gov/pubmed/9748581

Effects of frequent marijuana use on brain tissue volume and composition (abst - 1999)

http://www.ukcia.org/research/EffectsOfFrequentMarrijuanaUseOnBrainTissueVolumeAndComposition.ht m
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 116 - 120

Cannabinoid Receptor Messenger Rna Levels Decrease in a Subset of Neurons of the Lateral Striatum, Cortex and Hippocampus of Transgenic Huntington's Disease Mice. (abst - 2000)

http://medical-journals.healia.com/doc/10891614/Cannabinoid-receptor-messenger-RNA-levels-decrease- in-a-subset-of-neurons-of-the-lateral-striatum-cortex-and-hippocampus-of-transgenic-Huntingtons-disease- mice

Frequent Marijuana Use May Affect Brain Function But Not Structure (news - 2000)

http://www.sciencedaily.com/releases/2000/03/000331090541.htm
Cannabis and the brain. (full - 2003) http://brain.oxfordjournals.org/cgi/content/full/126/6/1252

Non-acute (residual) neurocognitive effects of cannabis use: A meta-analytic study (full - 2003) http://www.hnrc.ucsd.edu/publications_pdf/348art2003.pdf

Therapeutic potential of cannabinoids in CNS disease. (abst - 2003)

http://www.ncbi.nlm.nih.gov/pubmed/12617697

Lack of hippocampal volume change in long-term heavy cannabis users. (abst - 2005)

http://marijuana.researchtoday.net/archive/2/4/358.htm

A preliminary DTI study showing no brain structural change associated with adolescent cannabis use (full - 2006) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1524733&tool=pmcentrez

Effects of Alcohol and Combined Marijuana and Alcohol Use During Adolescence on Hippocampal Volume and Asymmetry (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1821342/?tool=pubmed

[FONT=Open Sans, Tahoma, Arial, sans-serif]Astrocytes Implicated In Machinery Of Cannabinoid Signaling[/FONT]

http://www.medicalnewstoday.com/releases/101891.php

New brain cells implicated in machinery of cannabinoid signaling

http://www.news-medical.net/news/2008/03/28/36739.aspx

The influence of substance use on adolescent brain development.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827693/?tool=pubmed

(news – 2008) (news – 2008)

(full- 2009)

(abst - 2009)
Neuroimaging in cannabis use: a systematic review of the literature.

http://www.unboundmedicine.com/medline/ebm/record/19627647/abstract/Neuroimaging_in_cannabis_use :_a_systematic_review_of_the_literature_

Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications (abst – 2009) http://pharmgkb.org/pmid/19897083

White Matter Integrity in Adolescents with Histories of Marijuana Use and Binge Drinking. (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19631736/abstract/White_Matter_Integrity_in_Ad olescents_with_Histories_of_Marijuana_Use_and_Binge_Drinking_
116

Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. (full – 2010) http://www.jneurosci.org/content/30/18/6273.long

Disposition of Cannabichromene, Cannabidiol, and Δ9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High- Performance Liquid Chromatography-Tandem Mass Spectrometry (abst - 2010) http://www.ingentaconnect.com/content/pres/jat/2010/00000034/00000008/art00012

Effects of synthetic cannabinoids on electroencephalogram power spectra in rats.
(abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21640532/abstract/Effects_of_synthetic_cannabino ids_on_electroencephalogram_power_spectra_in_rats_

Marijuana Compound Improves Brain And Liver Function In Animal Model Of Hepatic Encephalopathy (news – 2011) http://www.norml.org/index.cfm?Group_ID=8464

BRAIN TRAUMA

A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat. (abst – 1993) http://www.ncbi.nlm.nih.gov/pubmed/8411215

Development of HU-211 as a neuroprotectant for ischemic brain damage. (abst – 1995)

http://www.ncbi.nlm.nih.gov/pubmed/7477742

45Ca accumulation in rat brain after closed head injury; attenuation by the novel neuroprotective agent HU-211. (abst – 1995) http://www.ncbi.nlm.nih.gov/pubmed/7583233

Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant. (abst – 1997) http://www.ncbi.nlm.nih.gov/pubmed/9042110

How hash became a smash in brain trauma research (news - 1998)

http://www.maps.org/pipermail/maps_forum/1998-October/001231.html

Exogenous anandamide protects rat brain against acute neuronal injury in vivo. (full – 2001) http://www.jneurosci.org/content/21/22/8765.long

Brain Injury Circumvented by Endocannabinoids (abst - 2001)

http://stke.sciencemag.org/cgi/content/abstract/sigtrans;2001/104/tw380?maxtoshow=&hits=80&RESULT FORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1680&resourcetype=HWCIT

An endogenous cannabinoid (2-AG) is neuroprotective after brain injury. (abst - 2001)

http://www.ncbi.nlm.nih.gov/pubmed/11586361
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Cannabinoids on the Brain (full - 2002)

http://www.ukcia.org/research/CannabinoidsOnTheBrain.pdf

Cannabinoids and brain injury: therapeutic implications (full - 2002)

http://www.ukcia.org/research/CannabinoidsAndBrainInjury.pdf

Dexanabinol (HU-211) in the treatment of severe closed head injury: a randomized, placebo-controlled, phase II clinical trial. (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/11990913?dopt=Abstract

Marijuana Smoking Doesn't Kill (news - 2003)

http://www.webmd.com/smoking-cessation/news/20030918/marijuana-smoking-doesnt-kill.
Cannabinoids As Neuroprotective Agents in Traumatic Brain Injury. (abst - 2004) http://www.benthamdirect.org/pages/content.php?CPD/2004/00000010/00000018/0007B.SGM

The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. (abst - 2005) http://lib.bioinfo.pl/pmid:16364651

The Cannabinoid CB2 Receptor as a Target for Inflammation-Dependent Neurodegeneration (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435344/?tool=pmcentrez

The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16364651

The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis (full - 2007) http://www.jbc.org/content/282/33/23892.full

Endocannabinoids and traumatic brain injury. (abst – 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17952651

The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling. (full - 2008) http://www.fasebj.org/cgi/content/full/22/1/285

Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease
(full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750822/?tool=pmcentrez

Pre- and post-conditioning treatment with an ultra-low dose of Δ9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damage.
(abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21315768

N-arachidonoyl-L-serine is neuroprotective after traumatic brain injury by reducing apoptosis (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21505478/abstract/N_arachidonoyl_L_serine_is_n europrotective_after_traumatic_brain_injury_by_reducing_apoptosis_
118

Acute effects of a selective cannabinoid-2 receptor agonist on neuroinflammation in a murine model of traumatic brain injury (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21315768/abstract/Pre__and_post_conditioning_tr eatment_with_an_ultra_low_dose_of_%CE%949_tetrahydrocannabinol__THC__protects_against_pentyle netetrazole__PTZ__induced_cognitive_damage_

Acute effects of a selective cannabinoid-2 receptor agonist on neuroinflammation in a model of traumatic brain injury. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21332427/abstract/Acute_effects_of_a_selective_c annabinoid_2_receptor_agonist_on_neuroinflammation_in_a_murine_model_of_traumatic_brain_injury_

New metabolic pathway for controlling brain inflammation (news – 2011)

http://www.news-medical.net/news/20111021/New-metabolic-pathway-for-controlling-brain- inflammation.aspx

BREASTFEEDING/ INFANT APPETITE

The passage of 14C-delta-9-tetrahydrocannabinol into the milk of lactating squirrel monkeys. (abst – 1976) http://www.ncbi.nlm.nih.gov/pubmed/824699

Mammary excretion of cannabidiol in rabbits after intravenous administration.
(abst - 1994) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=7897602&dopt=abstract plus

Born with the munchies (news - 2000)

http://www.newscientist.com/article/mg16722461.600-born-with-the-munchies.html

Critical role of the endogenous cannabinoid system in mouse pup suckling and growth (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11426843

The endocannabinoid system: function in survival of the embryo, the newborn and the neuron. (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12395075

Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor. (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/12568912

Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/12678501

The endocannabinoid-CB(1) receptor system in pre- and postnatal life. (abst - 2004)

http://www.ncbi.nlm.nih.gov/pubmed/15464041

The endocannabinoid-CB receptor system: Importance for development and in pediatric disease. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15159678
119

Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood. (full - 2005) http://ebm.rsmjournals.com/cgi/content/full/230/4/225?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=1040&resourcetype=HWCIT

The cannabinoid system and its importance in the perinatal period (abst – 2005)

http://www.ncbi.nlm.nih.gov/pubmed/16266619

Endocannabinoids, feeding and suckling – from our perspective (full – 2006)

http://www.nature.com/ijo/journal/v30/n1s/full/0803274a.html

Inhibition of milk ingestion and growth after administration of a neutral cannabinoid CB1 receptor antagonist on the first postnatal day in the mouse. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17805201

Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137183/?tool=pubmed

Father: Medical marijuana eased pain of my cancer-battling son (anecdotal – 2011)

http://www.komonews.com/news/local/120941429.html

BULIMIA

Association study of cannabinoid receptor gene (CNR1) alleles and anorexia nervosa: differences between restricting and binging/purging subtypes. (abst – 2004) http://www.ncbi.nlm.nih.gov/pubmed/14755457

Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa. (full – 2005) http://www.nature.com/npp/journal/v30/n6/full/1300695a.html

Role of endocannabinoids and their analogues in obesity and eating disorders. (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/19011363

Elevated cannabinoid 1 receptor mRNA is linked to eating disorder related behavior and attitudes in females with eating disorders. (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19046818

Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia

nervosa and bulimia nervosa: evidence for synergistic effects. (abst – 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19659925
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 121 - 125

A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands.
(abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/19768813

The genetics of eating disorders. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21243475 Brain Type 1 Cannabinoid Receptor Availability in Patients with Anorexia and Bulimia

Nervosa. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21718968 Do Deficits in Brain Cannabinoids Contribute to Eating Disorders?

(news – 2011) http://www.sciencedaily.com/releases/2011/10/111031115226.htm

CANCER – BASAL CELL CARCINOMA - see CANCER – SKIN

CANCER – BLADDER / URETHRAL

TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20546877

CANCER - BONE

Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain.

(abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18611408

Reduction of bone cancer pain by activation of spinal cannabinoid receptor 1 and its

expression in the superficial dorsal horn of the spinal cord in a murine model of bone

cancer pain. (full - 2009)

http://journals.lww.com/anesthesiology/Fulltext/2009/07000/Reduction_of_Bone_Cancer_Pain_by_Activat ion_of.31.aspx

Spinal and peripheral analgesic effects of the CB cannabinoid receptor agonist AM1241

in two models of bone cancer-induced pain. (full - 2010)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931557/?tool=pubmed
121

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20176037

The endocannabinoid system and cancer: therapeutic implication (full – 2011)

http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01327.x/full

Antinociceptive effect of intrathecal cannabinoid receptor agonist WIN 55,212-2 in a rat bone tumor pain model (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21195743/abstract/Antinociceptive_effect_of_intra thecal_cannabinoid_receptor_agonist_WIN_55212_2_in_a_rat_bone_tumor_pain_model_

Antinociceptive effects induced through the stimulation of spinal cannabinoid type 2 receptors in chronically inflamed mice (abst - 2011) http://www.unboundmedicine.com/medline/ebm/record/21771590/abstract/Antinociceptive_effects_induce d_through_the_stimulation_of_spinal_cannabinoid_type_2_receptors_in_chronically_inflamed_mice_

CANCER - BREAST

The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation (full - 1998) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC20983/

Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation (full - 2000) http://endo.endojournals.org/cgi/content/full/141/1/118

Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222054/pdf/11485574.pdf/?tool=pmcentrez

Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma (full - 2006) http://jpet.aspetjournals.org/content/318/3/1375.full

9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer through Cdc2 Regulation (full - 2006) http://cancerres.aacrjournals.org/cgi/content/full/66/13/6615

Cannabinoids As Cancer Hope (article - 2006)

http://www.norml.org/index.cfm?Group_ID=6814

Anandamide inhibits adhesion and migration of breast cancer cells. (abst - 2006)

http://www.ncbi.nlm.nih.gov/pubmed/16343481?dopt=Abstract

Cannabidiol inhibits tumour growth in leukaemia and breast cancer in animal studies

(news - 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=220#2
122

A combination of THC and prochlorperazine effective in reducing vomiting in women following breast surgery (news - 2006) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=219#1

Cannabidiol Dramatically Inhibits Breast Cancer Cell Growth (news - 2006)

http://www.thehempire.com/index.php/cannabis/news/cannabidiol_dramatically_inhibits_breast_cancer_ce ll_growth_study_says

Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. (full - 2007) http://mct.aacrjournals.org/content/6/11/2921.long

Marijuana Chemical Against Breast Cancer! (news – 2007)

http://news.softpedia.com/news/Marijuana-Chemical-Against-Breast-Cancer-71346.shtml

Cannabis compound 'halts cancer' (news - 2007)

http://news.bbc.co.uk/2/hi/health/7098340.stm

Cannabis compound stops spread of breast cancer: researchers (news - 2007)

http://www.cbc.ca/health/story/2007/11/19/cannabis-cancer.html

―Medical Marijuana‖ Takes On New Meaning for Metastatic Breast Cancer (news - 2007) http://www.healthcentral.com/breast-cancer/c/78/16646/takes-cancer/

Cannabidiol may be helpful in reducing the aggressiveness of breast cancer cells
(news - 2007) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=258

Cannabis Compound May Stop Metastatic Breast Cancer (news - 2007)

http://www.washingtonpost.com/wp-dyn/content/article/2007/11/19/AR2007111900834.html
Marijuana Compound Shows Promise In Fighting Breast Cancer

http://www.sciencedaily.com/releases/2007/11/071123211703.htm

Cannabis compound may stop the spread of breast cancer cells

http://www.news-medical.net/news/2007/11/19/32672.aspx

Cannabis may stop Breast Cancer from spreading in the Body

(news - 2007) (news - 2007)

(news - 2007)
http://www.healthjockey.com/2007/11/21/cannabis-may-stop-breast-cancer-from-spreading-in-the-body/

Endocannabinoids in endocrine and related tumours (full - 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway. (full – 2008) http://erc.endocrinology-journals.org/cgi/content/full/15/4/965

Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776723/?tool=pubmed
123

Delta(9)-tetrahydrocannabinol inhibits 17beta-estradiol-induced proliferation and fails to activate androgen and estrogen receptors in MCF7 human breast cancer cells.
(full – 2008) http://ar.iiarjournals.org/content/28/1A/85.long

JunD is involved in the antiproliferative effect of Delta(9)-tetrahydrocannabinol on human breast cancer cells (abst - 2008) http://www.knockoutscience.com/showabstract.php?pmid=18454173

Cannabinoid receptor agonists inhibit growth and metastasis of breast cancer
(abst - 2008) http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2008/1_Annual_Meeting/4081?maxtosh ow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=480&resourcety pe=HWCIT

Inhibition of Breast Cancer Aggressiveness by Cannabidiol (abst - 2008)

http://cbcrp.org.127.seekdotnet.com/research/PageGrant.asp?grant_id=4903

Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer (full - 2009) http://mct.aacrjournals.org/content/8/11/3117.full

Phantom breast syndrome. (full – 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902108/?tool=pubmed

Cannabinoids in the treatment of cancer. (abst – 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19442435

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917429/?tool=pmcentrez

Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2). (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/19887017

A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20590578

Abstract P1-11-23: Cannabinoid Receptor 2 Compounds in the Attenuation of Breast Cancer Cell Proliferation: Mechanisms of Action (abst – 2010) http://cancerres.aacrjournals.org/cgi/content/meeting_abstract/70/24_MeetingAbstracts/P1-11- 23?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=400 &sortspec=date&resourcetype=HWCIT

Cannabidiol researchers discover the switch to turn off aggressive breast cancer gene (news - 2010) http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2010m3d7-Cannabidiol- researchers-discover-the-switch-to-turn-off-agressive-breast-cancer-gene
124

Medical marijuana news. Cannabidiol stops the spread of breast cancer. (news - 2010)

http://www.examiner.com/x-19678-Cannabis-Revolution-Examiner~y2010m2d27-Medical-marijuana- news--Cannabidiol-stops-the-spread-of-breast-cancer

The endocannabinoid system and cancer: therapeutic implication (full – 2011)

http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01327.x/full

Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168464/?tool=pubmed

Novel hexahydrocannabinol analogs as potential anti-cancer agents inhibit cell proliferation and tumor angiogenesis. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/20950604

Cannabidiol induces programmed cell death in breast cancer cells by coordinating the crosstalk between apoptosis and autophagy. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21566064

Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/20859676

Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21995886

CANCER - CERVICAL

Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells via aberrantly expressed vanilloid receptor-1 (full - 2004) http://science.iowamedicalmarijuana.org/pdfs/cancer/Contassot 2004.pdf

Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells (news - 2007)

http://www.webmd.com/cancer/news/20071226/pot-slows-cancer-in-test-tube

The influence of mast cell mediators on migration of SW756 cervical carcinoma cells. (full – 2008) http://www.jstage.jst.go.jp/article/jphs/106/2/106_208/_article

Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full - 2008) http://jnci.oxfordjournals.org/cgi/content/full/100/1/59

Marijuana use and cervical HPV/neoplasia (abst - 2008)

http://www.infectagentscancer.com/content/4/S2/P15
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 126 - 130

R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19015962

Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19914218

Crosstalk between Chemokine Receptor CXCR4 and Cannabinoid Receptor CB(2) in Modulating Breast Cancer Growth and Invasion. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168464/?tool=pubmed
CANCER – CHEMOTHERAPY- see CHEMOTHERAPY

CANCER – CHOLANGIOCARCINOMA

Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth

http://www.jbc.org/content/282/17/13098.full

(full - 2007)
The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604798/?tool=pmcentrez

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full – 2008) http://gut.bmj.com/content/57/8/1140.full

Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872061/?tool=pubmed

Recent advances in the regulation of cholangiocarcinoma growth (abst - 2010)

http://ajpgi.physiology.org/cgi/content/abstract/299/1/G1?maxtoshow=&hits=80&RESULTFORMAT=&fu lltext=cannabinoid&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT

The dual effects of delta(9)-tetrahydrocannabinol on cholangiocarcinoma cells: anti- invasion activity at low concentration and apoptosis induction at high concentration. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/19916793

Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21464819
126

The novel cannabinoid receptor GPR55, inhibits cholangiocarcinoma growth
(abst – 2011) http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/1117.3?maxtoshow=&hits=80 &RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcety pe=HWCIT

CANCER – COLON /COLORECTAL


Possible endocannabinoid control of colorectal cancer growth. (abst - 2003)

Possible endocannabinoid control of colorectal can... [Gastroenterology. 2003] - PubMed result

Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. (full - 2004)
Inflammation and Cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation

Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. (abst - 2004)
Agonists of cannabinoid receptor 1 and 2 inhibit e... [Am J Physiol Gastrointest Liver Physiol. 2006] - PubMed result

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2 (full - 2005)
The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2

A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells (full – 2005)
A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells

Cannabinoids and cancer: potential for colorectal cancer therapy. (abst - 2005)

Cannabinoids and cancer: potential for colorectal ... [Biochem Soc Trans. 2005] - PubMed result

A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells. (full - 2006) http://molpharm.aspetjournals.org/content/70/1/51.long

Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth : RECRUITMENT OF Fas AND Fas LIGAND TO LIPID RAFTS (full – 2007) http://www.jbc.org/content/282/17/13098.full

The cannabinoid CB(2) receptor: a good friend in the gut. (abst – 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17727390

The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17583570
127

Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755791/?tool=pubmed

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full – 2008) http://gut.bmj.com/content/57/8/1140.full

Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha- mediated ceramide de novo synthesis in colon cancer cells. (full – 2008) http://clincancerres.aacrjournals.org/content/14/23/7691.long

Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth

Turned-off Cannabinoid Receptor Turns On Colorectal Tumor Growth

Marijuana takes on colon cancer (news - 2008)

Marijuana takes on colon cancer - health - 01 August 2008 - New Scientist

(news - 2008)
Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer (news - 2008)

HealthScout-Consumer Health News, Information and Resources Updated Daily-Cancer-Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer

Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer (news – 2008) http://www.news-medical.net/news/2008/08/03/40485.aspx

Induction of the antitumorigenic NSAID-activated gene (NAG-1) in synthetic hexahydrocannabinol-induced apoptosis of human colorectal cancer cells (abst - 2009) http://www.fasebj.org/cgi/content/meeting_abstract/23/1_MeetingAbstracts/761.5?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HW CIT

Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil. (abst + 1st page – 2009) http://www.springerlink.com/content/45008p9643k139l4/

Cannabinoids in intestinal inflammation and cancer (abst - 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19442536

US Patent Application 20100222437 - COMPOSITION CONTAINING NON- PSYCHOTROPIC CANNABINOIDS FOR THE TREATMENT OF INFLAMMATORY DISEASES (full – 2010) http://www.patentstorm.us/applications/20100222437/fulltext.html

Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20592049

Effects of anandamide on polyamine levels and cell growth in human colon cancer cells (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20682986
128

Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependent NSAID-activated gene-1 in colon cancer cells
(abst - 2010) http://www.sciencedirect.com/science/article/pii/S0006295210001735

Involvement of NSAID-activated gene-1 in a novel synthetic hexahydrocannabinol analogue-induced growth inhibition and apoptosis of colon cancer cells (abst - 2010) http://www.fasebj.org/cgi/content/meeting_abstract/24/1_MeetingAbstracts/965.8?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HW CIT

The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells. (abst, link to PDF - 2010)

http://www.spandidos-publications.com/ijo/37/1/187

Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa. (full – 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf

Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21412772

Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22110202

Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22231745

CANCER - ENDOMETRIAL

The Levels of the Endocannabinoid Receptor CB2 and Its Ligand 2- Arachidonoylglycerol Are Elevated in Endometrial Carcinoma (full – 2010) http://endo.endojournals.org/content/151/3/921.full

CANCER - GASTRIC

Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol (dronabinol). (abst - 1997) http://www.ncbi.nlm.nih.gov/pubmed/9392925

The effect of cannnabinoid to gastric cancer (abst - 2006)

http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/958- a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1360 &resourcetype=HWCIT
129

Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/19394652

Effect of a synthetic cannabinoid agonist on the proliferation and invasion of gastric cancer cells. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20336665

Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21312237

CANCER – GLIOMA (brain cancer)
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells.

(full - 1992) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525583/ Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells. (abst - 1998)

http://www.ncbi.nlm.nih.gov/pubmed/9771884

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors (full - 2000)

http://www.jbc.org/content/275/41/31938.full

Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. (full - 2000) http://depts.washington.edu/stellalb/images/Nature2000.pdf

Marijuana's Active Ingredient Targets Deadly Brain Cancer (news - 2000)

http://www.webmd.com/news/20000228/marijuanas-active-ingredient-targets-deadly-brain-cancer

Pot Shrinks Tumors; Government Knew in '74 (news - 2000)

http://www.alternet.org/story/9257/?page=entire

Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2 Cannabinoid Receptor1 (full - 2001) http://cancerres.aacrjournals.org/cgi/reprint/61/15/5784.pdf

Inhibition of Rat C6 Glioma Cell Proliferation by Endogenous and Synthetic Cannabinoids. Relative Involvement of Cannabinoid and Vanilloid Receptors (full - 2001) http://jpet.aspetjournals.org/content/299/3/951.full

Anti-Tumor Effects (news - 2001) http://www.ukcia.org/research/AntiTumorEffects.htm

Inhibition of tumor angiogenesis by cannabinoids (full - 2003)

http://www.fasebj.org/cgi/reprint/02- 0795fjev1?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cannabis&andorexactfulltext=and&sear chid=1&FIRSTINDEX=20&sortspec=relevance&resourcetype=HWCIT
130
 

momofthegoons

Vapor Accessory Addict
Staff member
Pages 131 - 135

Cannabinoids: Potential Anticancer Agents (full - 2003)

http://americanmarijuana.org/Guzman-Cancer.pdf

Anti-tumor effects of cannabidiol (abst - 2003)

http://www.hempworld.com/HempPharm/articles/milanstudy.html

Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid. (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/12948856

Up-Regulation of Cyclooxygenase-2 Expression Is Involved in R(_)-Methanandamide- Induced Apoptotic Death of Human Neuroglioma Cells (full - 2004) http://science.iowamedicalmarijuana.org/pdfs/cancer/Hinz 2004.pdf

Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas (full - 2004) http://cancerres.aacrjournals.org/cgi/content/full/64/16/5617

Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. (full - 2004) http://science.iowamedicalmarijuana.org/pdfs/cancer/Massi 2004.pdf

Hypothesis: Cannabinoid Therapy for the Treatment of Gliomas? (abst - 2004)

http://medical-journals.healia.com/doc/15275820/Hypothesis-cannabinoid-therapy-for-the-treatment-of- gliomas

Arachidonylethanolamide induces apoptosis of human glioma cells through vanilloid receptor-1. (abst – 2004) http://www.ncbi.nlm.nih.gov/pubmed/15453094

Cannabis extract shrinks brain tumours (news – 2004)

http://www.newscientist.com/article/dn6283

'Cannabis' brain tumour drug hope (news - 2004)

http://news.bbc.co.uk/2/hi/health/3561686.stm

Marijuana May Stall Brain Tumor Growth (news - 2004)

http://www.webmd.com/cancer/news/20040815/marijuana-stall-brain-tumor-growth

Marijuana Extract Fights Brain Cancer in Mice (news - 2004)

http://www.scientificamerican.com/article.cfm?id=marijuana-extract-fights
Cancer Killer (news - 2004) http://www.november.org/stayinfo/breaking2/CancerKiller.html

Marijuana Ingredient Inhibits VEGF Pathway Required For Brain Tumor Blood Vessels (news - 2004) http://www.sciencedaily.com/releases/2004/08/040816085401.htm

Cannabis extract makes brain tumors shrink, halts growth of blood vessels (news - 2004) http://www.medicalnewstoday.com/articles/12088.php
131

Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor- independent mechanism (full - 2005) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1576089&tool=pmcentrez

Endocannabinoid metabolism in human glioblastomas and meningiomas compared to human non-tumour brain tissue (full - 2005) http://www.ukcia.org/research/EndocannabinoidMetabolismInHumanGlioblastomasAndMeningiomas.pdf

Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16078104?dopt=Abstract

Effects on cell viability. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/16596790

A pilot clinical study of Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. (full - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=193

The non-psychoactive Cannabidiol triggers caspase activation and oxidative stress in human glioma cells. (abst - 2006)

http://www.ihop-net.org/UniPub/iHOP/pm/12214911.html?pmid=16909207

Acyl-based anandamide uptake inhibitors cause rapid toxicity to C6 glioma cells at pharmacologically relevant concentrations. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16899063

R(+)-methanandamide elicits a cyclooxygenase-2-dependent mitochondrial apoptosis signaling pathway in human neuroglioma cells. (abst – 2006) http://www.springerlink.com/content/l403431l1728x733/

Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma. (abst – 2006) http://www.springerlink.com/content/75pu360830261968/

Cannabinoids Curb Brain Tumor Growth, First-Ever Patient Trial Shows (news – 2006)

http://www.norml.org/index.cfm?Group_ID=6947

THC tested against brain tumour in pilot clinical study (news - 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=222#1

Cannabinoids Induce Glioma Stem-like Cell Differentiation and Inhibit Gliomagenesis (full - 2007) http://www.jbc.org/content/282/9/6854.long

Expression of cannabinoid receptors and neurotrophins in human gliomas. (abst - 2007)

http://www.ncbi.nlm.nih.gov/pubmed/18175076

Targeting astrocytomas and invading immune cells with cannabinoids: a promising therapeutic avenue. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17952648
132

Cannabinoids and gliomas. (abst - 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17952650?dopt=Abstract

New Study: Marijuana Might Cure Brain Tumors (news – 2007)

http://stopthedrugwar.org/speakeasy/2007/oct/18/new_study_marijuana_might_cure_b

Cannabinoids as potential new therapy for the treatment of gliomas (full - 2008)

http://safeaccess.ca/research/pdf/ParolaroCBasTherapyforGliomas2008.pdf

US Patent Application 20080262099 - Inhibition of Tumour Cell Migration (full – 2008) http://www.patentstorm.us/applications/20080262099/fulltext.html

Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression (full - 2008) http://cancerres.aacrjournals.org/cgi/content/full/68/6/1945

Delta 9-tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/17934890

Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas: a new marker of cannabinoid antitumoral activity? (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/17675107

5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid. (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/18028339

High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18615640

Marijuana Kills Brain Cancer Cells (news - 2008)

http://www.entheology.org/edoto/anmviewer.asp?a=375

Cannabinoid action induces autophagymediated cell death through stimulation of ER stress in human glioma cells. (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673842/?tool=pmcentrez

TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action. (full – 2009)

http://www.landesbioscience.com/journals/autophagy/SalazarAUTO5-7.pdf

Amphiregulin is a factor for resistance of glioma cells to cannabinoid-induced apoptosis (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19229996

THC initiates brain cancer cells to destroy themselves (news - 2009)

http://www.worldhealth.net/news/thc_initiates_brain_cancer_cells_to_dest/

Marijuana ingredient may reduce tumours-study (news - 2009)

http://www.alertnet.org/thenews/newsdesk/LV470563.htm
133

Active Ingredient in Marijuana Kills Brain Cancer Cells (news - 2009)

http://health.usnews.com/health-news/family-health/cancer/articles/2009/04/01/active-ingredient-in- marijuana-kills-brain-cancer.html

Marijuana Chemical May Fight Brain Cancer (news - 2009)

http://www.webmd.com/cancer/brain-cancer/news/20090401/marijuana-chemical-may-fight-brain-cancer

Active Component Of Marijuana Has Anti-Cancer Effects, Study Suggests (news - 2009) http://www.sciencedaily.com/releases/2009/04/090401181217.htm

Anti-Cancer Effects In Active Component Of Marijuana (news – 2009)

http://www.medicalnewstoday.com/releases/144770.php

Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival (full - 2010) http://www.letfreedomgrow.com/cmu/Brain_Cancer_Study.pdf

The expression level of CB1 and CB2 receptors determines their efficacy at inducing apoptosis in astrocytomas. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806825/?tool=pubmed

Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919281/?tool=pubmed

Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20307616

Cannabinoids inhibit glioma cell invasion in brain cancer studies (news - 2010)

http://www.examiner.com/x-19678-Cannabis-Revolution-Examiner~y2010m3d11-Cannabinoids-inhibit- glioma-cell-invasion-in-brain-cancer-studies

Cannabis Rx: Cutting Through the Misinformation : Dr. Andrew Weil (news - 2010)

http://www.huffingtonpost.com/andrew-weil-md/can-cannabis-treat-cancer_b_701005.html

Cannabis Inhalation Associated With Spontaneous Tumor Regression
(news - 2010) http://blog.norml.org/2011/03/22/cannabis-inhalation-associated-with-spontaneous-tumor-regression-study- says/

Molecular Mechanisms Involved in the Antitumor Activity of Cannabinoids on Gliomas: Role for Oxidative Stress (abst/ click for full PDF – 2011) http://www.mdpi.com/2072-6694/2/2/1013/

Spontaneous regression of septum pellucidum/forniceal pilocytic astrocytomas-possible role of Cannabis inhalation. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21336992

A combined preclinical therapy of cannabinoids and temozolomide against glioma. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21220494
134

Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21233844

Marijuana Compound Induces Cell Death In Hard-To-Treat Brain Cancer (news – 2011) http://www.norml.org/index.cfm?Group_ID=8459

Inhaled Cannabis May Keep Brain Cancer in Remission (news – 2011)

http://www.freedomisgreen.com/inhaled-marijuana-may-keep-brain-cancer-in-remission/

CANCER - HEAD AND NECK

Marijuana Unlikely to Cause Head, Neck, or Lung Cancer (news - 2000)

http://www.webmd.com/smoking-cessation/news/20000508/marijuana-unlikely-to-cause-cancer

Marijuana use and Risk of Oral Squamous Cell Carcinoma (full - 2004)

http://cancerres.aacrjournals.org/content/64/11/4049.full

Cannabis use and cancer of the head and neck: Case-control study (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277494/

A population-based case-control study of marijuana use and head and neck squamous cell carcinoma. (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812803/?tool=pubmed

Marijuana May Reduce Risk of Certain Cancers, Study Says (news - 2009)
http://www.drugfree.org/uncategorized/marijuana-may-reduce-risk-of

CANCER - KAPOSI'S SARCOMA

THC inhibits lytic replication of gamma oncogenic herpes viruses in vitro

http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=521080

The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human Kaposi‘s sarcoma cells in vitro (full - 2009) http://science.iowamedicalmarijuana.org/pdfs/cancer/Luca et al 2009 19539619.pdf

Recreational Drug Use and Risk of Kaposi's Sarcoma in HIV- and HHV-8-Coinfected

Homosexual Men (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981355/?tool=pubmed
(full - 2004)
135
 

momofthegoons

Vapor Accessory Addict
Staff member
Pages 136 - 140

CANCER – KIDNEY


Cannabinoid CB1 Receptor Is Downregulated in Clear Cell Renal Cell Carcinoma (full - 2010) http://jhc.sagepub.com/content/58/12/1129.long

CANCER - LEUKEMIA


Effects of cannabinoids on L1210 murine leukemia. 1. Inhibition of DNA synthesis. (abst - 1977) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=897352&dopt=abstractp lus

Cannabinoids induce incomplete maturation of cultured human leukemia cells
(full - 1987) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC298868/?tool=pmcentrez&page=1

Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient. (full - 1988) http://chestjournal.chestpubs.org/content/94/2/432.long

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors (full - 2000) http://www.jbc.org/content/275/41/31938.full

Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (full - 2002) http://bloodjournal.hematologylibrary.org/cgi/reprint/100/2/627.pdf

Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells. (abst - 2003) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=14692532&dopt=abstrac tplus

Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway (full - 2005) http://bloodjournal.hematologylibrary.org/cgi/content/full/105/3/1214

Marijuana's Active Ingredient Kills Leukemia Cells (forum post/news - 2005)

http://www.treatingyourself.com/vbulletin/showthread.php?t=7107

Cannabidiol-Induced Apoptosis in Human Leukemia Cells : A Novel Role of

Cannabidiol in the Regulation of p22phox and Nox4 Expression (full - 2006)

http://molpharm.aspetjournals.org/cgi/content/full/70/3/897
136

{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells Is Regulated by Translocation of Bad to Mitochondria (full - 2006) http://mcr.aacrjournals.org/content/4/8/549.full

Is there a temperature-dependent uptake of anandamide into cells? ( full – 2006)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1629410/

Parental marijuana use and risk of childhood acute myeloid leukaemia: a report from the Children's Cancer Group (United States and Canada). (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16466429

The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16458258

Cannabis destroys cancer cells (news - 2006)

http://www.news-medical.net/news/2006/03/01/16340.aspx

Cannabidiol inhibits tumour growth in leukaemia and breast cancer in animal studies (news - 2006) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=220#2

HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor (full - 2007)

http://mct.aacrjournals.org/content/6/1/173.long

Medical Marijuana Use and Research Leukemia & Lymphoma Society Statement (full – 2008) http://www.maps.org/mmj/lnls-res.pdf

Enhancing the in vitro cytotoxic activity of Delta9-tetrahydrocannabinol in leukemic cells through a combinatorial approach (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18608861

Substance use and survival after treatment for chronic myelogenous leukemia (CML) or myelodysplastic syndrome (MDS). (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847847/?tool=pubmed

Cannabidiol induced a contrasting pro-apoptotic effect between freshly isolated and precultured human monocytes. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/20471992/abstract/Cannabidiol_induced_a_contras ting_pro_apoptotic_effect_between_freshly_isolated_and_precultured_human_monocytes_

CANCER – LIVER

Overexpression of cannabinoid receptors CB1 and CB2 correlates with improved

prognosis of patients with hepatocellular carcinoma. (abst – 2006)

http://www.ncbi.nlm.nih.gov/pubmed/17074588
137

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full – 2008) http://gut.bmj.com/content/57/8/1140.full

Apoptosis induced in HepG2 cells by the synthetic cannabinoid WIN: involvement of the transcription factor PPARgamma. (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19059457

The synthetic cannabinoid WIN 55,212-2 sensitizes hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating p8/CCAAT/enhancer binding protein homologous protein (CHOP)/death receptor 5 (DR5) axis. (full – 2010) http://molpharm.aspetjournals.org/content/77/5/854.long

The effect of the activation of cannabinoid receptor on the proliferation and apoptosis of hepatoma HepG2 cells (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20368112

Membrane cholesterol mediates the endocannabinoids-anandamide affection on HepG2 cells (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20380798

Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK- dependent activation of autophagy. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21475304

CANCER - LUNG

A pilot study of orally administered Δ1-trans-tetrahydrocannabinol in the management of patients undergoing radiotherapy for carcinoma of the bronchus (full - 1974) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402430/?tool=pmcentrez&page=1

Anticancer activity of cannabinoids (full - 1975)

http://drugpolicycentral.com/bot/pg/cancer/THC_cancer_sep_1975.htm

Antineoplastic activity of cannabinoids (full - 1975)

http://www.ukcia.org/research/AntineoplasticActivityOfCannabinoids/default.html

In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas. (abst - 1977) http://www.ncbi.nlm.nih.gov/pubmed/616322

Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. (full - 1983) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011510/?tool=pmcentrez&page=1

No increase in carcinogen-DNA adducts in the lungs of monkeys exposed chronically to marijuana smoke. (abst – 1992) http://www.ncbi.nlm.nih.gov/pubmed/1488780
138

Marijuana Less Harmful to Lungs than Cigarettes (news - 1994)

http://www.ukcia.org/research/lungs.php

So, you thought it was the tar that caused cancer... (news – 1999)

http://www.ukcia.org/research/cancer2.php

Marijuana Unlikely to Cause Head, Neck, or Lung Cancer (news - 2000)

http://www.webmd.com/smoking-cessation/news/20000508/marijuana-unlikely-to-cause-cancer Anti-Tumor Effects (news - 2001) http://www.ukcia.org/research/AntiTumorEffects.htm
Cannabis and tobacco smoke are not equally carcinogenic. (full – 2005)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1277837/?tool=pubmed

Smoking Cannabis Does Not Cause Cancer of Lung or Upper Airways

http://ccrmg.org/journal/05aut/nocancer.html

Cannabis Smoke Is Less Likely To Cause Cancer Than Tobacco Smoke

http://www.sciencedaily.com/releases/2005/10/051019003339.htm

(news - 2005)


(news - 2005)
Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a

Population-Based Case-Control Study (full - 2006)

http://cebp.aacrjournals.org/content/15/10/1829.full

Marijuana Use and Lung Cancer: Results of a Case-Control Study

http://www.ukcia.org/research/MjUseAndLungCancer.php

Study Finds No Link Between Marijuana Use And Lung Cancer

http://www.sciencedaily.com/releases/2006/05/060526083353.htm

Study Finds No Cancer-Marijuana Connection (news – 2006)

(abst - 2006) (news - 2006)
http://www.washingtonpost.com/wp-dyn/content/article/2006/05/25/AR2006052501729_pf.html

No association between lung cancer and cannabis smoking in large study (news - 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=219#2

Marijuana Smoking Found Non-Carcinogenic (news - 2006)

http://www.medpagetoday.com/HematologyOncology/LungCancer/tb/3393

Pot Smoking Not Linked to Lung Cancer (news - 2006)

http://www.entheology.org/edoto/anmviewer.asp?a=246

Large Study Finds No Link between Marijuana and Lung Cancer

http://www.scientificamerican.com/article.cfm?id=large-study-finds-no-link

(news - 2006)
There Seems to Be No Link between Marijuana Use and Lung Cancer (news – 2006)

http://news.softpedia.com/news/There-Seems-to-Be-No-Link-between-Marijuana-Use-and-Lung-Cancer- 24575.shtml
139

{Delta}-9 Tetrahydrocannabinol inhibits growth and metastasis of lung cancer.
(abst - 2007) http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2007/1_Annual_Meeting/4749?maxtosh ow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1760&resourcet ype=HWCIT

Marijuana Cuts Lung Cancer Tumor Growth In Half, Study Shows (news – 2007)

http://www.sciencedaily.com/releases/2007/04/070417193338.htm

Pot's Active Ingredient Halts Lung Cancer Growth, Study Says (news - 2007)

http://www.illinoisnorml.org/content/view/529/27/

Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells
(news - 2007) http://www.webmd.com/cancer/news/20071226/pot-slows-cancer-in-test-tube

Marijuana Helps to Combat Lung Cancer (news – 2007)

http://www.bio-medicine.org/medicine-news/Marijuana-Helps-to-Combat-Lung-Cancer-20045-1/

Marijuana May Fight Lung Tumors (news - 2007)

http://www.webmd.com/lung-cancer/news/20070417/marijuana-may-fight-lung-tumors

Cannabis as a possible treatment for lung cancer (news - 2007)

http://arstechnica.com/science/news/2007/04/cannabis-as-a-possible-treatment-for-lung-cancer.ars

Marijuana Beneficial in Fighting Lung Tumors, Study (news – 2007)

http://www.bio-medicine.org/medicine-news/Marijuana-Beneficial-in-Fighting-Lung-Tumors--Study- 20037-1/

Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full - 2008) http://jnci.oxfordjournals.org/cgi/content/full/100/1/59

Doubts about the role of cannabis in causing lung cancer. (letter - 2008)

http://erj.ersjournals.com/cgi/content/full/32/3/815

Delta9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/17621270?dopt=Abstract

Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20668920

Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19914218
140
 

momofthegoons

Vapor Accessory Addict
Staff member
Pages 141 - 145

Medical Marijuana; The active ingredient in marijuana cuts tumor growth in common

lung cancer in half and significantly reduces the ability of the cancer to spread, say

researchers at Harvard University. (news – 2010)

http://www.thefreelibrary.com/Medical+Marijuana;+The+active+ingredient+in+marijuana+cuts+tumor ...-a0243683610

Effects of smoking cannabis on lung function (full – 2011)

http://www.expert-reviews.com/doi/full/10.1586/ers.11.40

Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis (full - 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025486/?tool=pubmed

Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22198381

CANCER - LYMPHOMA

UCSF Researchers Report New Risk Factors For Non-Hodgkin's Lymphoma (news - 1999) http://www.sciencedaily.com/releases/1999/08/990817065339.htm

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors (full - 2000) http://www.jbc.org/content/275/41/31938.full

Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (full - 2002) http://bloodjournal.hematologylibrary.org/cgi/content/full/100/2/627

Lymphoma may be slowed by cannabis (news - 2002)

http://marijuana-ro.com/medical-usage/lymphoma-may-be-slowed-by-cannabis.html

Cannabinoid Receptor Agonists May Be Novel Class of Anti-Lymphoma Agents (news - 2002) http://www.oncolink.org/resources/article.cfm?c=3&s=8&ss=23&Year=2002&Month=7&id=8667

High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma (abst – 2003) http://pharmgkb.org/pmid/12970790

The Peripheral Cannabinoid Receptor CB2 and CD40 Are Novel Biological Markers That Predict Outcome in Diffuse Large B-Cell Lymphoma of Elderly Patients.
(abst - 2004)

http://abstracts.hematologylibrary.org/cgi/content/abstract/104/11/3256?maxtoshow=&hits=80&RESULTF ORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT
141

Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16337199?dopt=Abstract

Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma (full - 2006) http://molpharm.aspetjournals.org/content/70/5/1612.full

The expression of the peripheral cannabinoid receptor on cells of the immune system and non-Hodgkin's lymphomas. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/17613768

Medical Marijuana Use and Research Leukemia & Lymphoma Society Statement (full – 2008) http://www.maps.org/mmj/lnls-res.pdf

Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: growth inhibition by receptor activation. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18546271

Cannabis Agonist Reduces Non-Hodgkin Lymphoma Tumor Growth, says study (news - 2008) http://www.illinoisnorml.org/content/view/957/27/

Potentiation of cannabinoid-induced cytotoxicity in mantle cell lymphoma through modulation of ceramide metabolism. (full - 2009) http://mcr.aacrjournals.org/content/7/7/1086.long

WIN55,212-2 induces cytoplasmic vacuolation in apoptosis-resistant MCL cells. (full – 2011) http://www.nature.com/cddis/journal/v2/n11/full/cddis2011106a.html

CANCER - MELANOMA

Intractable nausea and vomiting due to gastrointestinal mucosal metastases (abst - 1997)


http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=35

Cannabinoid receptors as novel targets for the treatment of melanoma (full - 2006)

http://www.fasebj.org/cgi/content/full/20/14/2633?ijkey=958a31584b617c871b46ef1af541c90cc0fb0f14

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases. (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=180

Cannabinoid receptor-1 modulation induces apoptosis of human melanoma cells
(abst - 2008) http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2008/1_Annual_Meeting/2678?maxtosh ow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcety pe=HWCIT
142

Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21298280

The antimitogenic effect of the cannabinoid receptor agonist WIN55212-2 on human melanoma cells is mediated by the membrane lipid raft. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21807457

CANCER - NEUROBLASTOMA

Inhibition of neuroblastoma adenylate cyclase by cannabinoid and nantradol compounds (abst – 1984) http://www.ncbi.nlm.nih.gov/pubmed/6090851

Cannabinoid inhibition of adenylate cyclase. Biochemistry of the response in neuroblastoma cell membranes. (abst – 1985) http://www.ncbi.nlm.nih.gov/pubmed/2984538

Interaction of delta-9-tetrahydrocannabinol with rat B103 neuroblastoma cells. (abst – 1987) http://www.ncbi.nlm.nih.gov/pubmed/2821958

Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. (full - 1992) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525583/

Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism. (full - 1992) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1907498/?tool=pmcentrez&page=1

Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by delta 9- tetrahydrocannabinol (THC). (abst – 1995) http://www.ncbi.nlm.nih.gov/pubmed/7702643

Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells. (abst – 1996) http://www.ncbi.nlm.nih.gov/pubmed/8858137

Tau protein after delta-9-tetrahydrocannabinol in a human neuroblastoma cell line. (abst – 1996) http://www.ncbi.nlm.nih.gov/pubmed/8981058

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors (full - 2000)

http://www.jbc.org/content/275/41/31938.full

A predominant role for inhibition of the adenylate cyclase/protein kinase A pathway in ERK activation by cannabinoid receptor 1 in N1E-115 neuroblastoma cells.
(full – 2003) http://www.jbc.org/content/278/49/48973.long
143

Characterization of the Endocannabinoid System in Human Neuronal Cells and Proteomic Analysis of Anandamide-induced Apoptosis (full – 2009) http://www.jbc.org/content/284/43/29413.full

Increasing Antiproliferative Properties of Endocannabinoids in N1E-115 Neuroblastoma Cells through Inhibition of Their Metabolism. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203169/?tool=pubmed

CANCER - ORAL

Boron trifluoride etherate on silica-A modified Lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells. (abst - 1998) http://www.ncbi.nlm.nih.gov/pubmed/9875457

Marijuana use and Risk of Oral Squamous Cell Carcinoma (full - 2004)

http://cancerres.aacrjournals.org/content/64/11/4049.full

Study Finds No Association Between Marijuana Use And Incidence Of Oral Cancer (news - 2004) http://www.sciencedaily.com/releases/2004/06/040602063428.htm

Smoking of cannabis does not increase risk for oral cancer (news - 2004)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=175#1

Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study (full - 2006) http://cebp.aacrjournals.org/content/15/10/1829.full

Peripheral Cannabinoids Attenuate Carcinoma Induced Nociception in Mice (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771220/

A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma. (full - 2009) http://safeaccess.ca/research/pdf/MarijuanaUse_and_Head-NeckSquamousCellCarcinoma.pdf

Cannabinoids Inhibit Cellular Respiration of Human Oral Cancer Cells (full - 2010)

http://content.karger.com/produktedb/produkte.asp?DOI=000312686&typ=pdf

Cannabinoids attenuate cancer pain and proliferation in a mouse model. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21094209
144

CANCER - OVARIAN

Cannabinoid receptors as a target for therapy of ovarian cancer (abst - 2006)

http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/1084?maxtoshow=&hits=80&RESULTF ORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT

The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/20838378

CANCER - PANCREATIC

Pancreatitis & Medical Marijuana (article - no date)

http://onlinepot.org/medical/pancreatitis.htm

Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress–Related Genes (full - 2006) http://cancerres.aacrjournals.org/cgi/content/full/66/13/6748

Cannabinoid derivatives induce cell death in pancreatic MIA PaCa-2 cells via a receptor- independent mechanism. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16500647

Cannabinoids Halt Pancreatic Cancer, Breast Cancer Growth, Studies Say (news - 2006)

http://www.thehempire.com/index.php/cannabis/news/cannabinoids_halt_pancreatic_cancer_breast_cancer _growth_studies_say

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full – 2008) http://gut.bmj.com/content/57/8/1140.full

Cannabinoids in pancreatic cancer: Correlation with survival and pain (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225529/?tool=pmcentrez

TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action. (full – 2009)

http://www.landesbioscience.com/journals/autophagy/SalazarAUTO5-7.pdf

Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells

through a ROS-mediated mechanism. (full – 2011)

http://www.nature.com/cddis/journal/v2/n4/pdf/cddis201136a.pdf
145
 

momofthegoons

Vapor Accessory Addict
Staff member
Pages 146 - 150

CANCER - PITUITARY ADENOMA

Normal Human Pituitary Gland and Pituitary Adenomas Express Cannabinoid Receptor

Type 1 and Synthesize Endogenous Cannabinoids: First Evidence for a Direct Role of

Cannabinoids on Hormone Modulation at the Human Pituitary Level (full - 2001)

http://jcem.endojournals.org/cgi/content/full/86/6/2687?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=marihuana&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT

CANCER – PNET / PRIMITIVE NEUROECTODERMAL TUMOR
Distinctive pattern of cannabinoid receptor type II (CB2) expression in adult and

pediatric brain tumors. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/17239827 Father: Medical marijuana eased pain of my cancer-battling son (anecdotal – 2011)

http://www.komonews.com/news/local/120941429.html

CANCER - PROSTATE

Δ9-Tetrahydrocannabinol induces apoptosis in human prostate PC-3 cells via a receptor- independent mechanism (abst - 1999) http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T36-3XFTGPR- X&_user=10&_coverDate=09%2F24%2F1999&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docancho r=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=e9b3e817c7d39ac7f206 56f24e07dfd1

Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by

Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell

Proliferation (full - 2000)

http://endo.endojournals.org/cgi/content/full/141/1/118?ijkey=9caa0af787d8b2dc94e45918a69b40ea90bc1 776

Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/12746841?dopt=Abstract

Expression of functionally active cannabinoid receptor CB1 in the human prostate gland (abst – 2003) http://onlinelibrary.wiley.com/doi/10.1002/pros.10165/abstract

2-Arachidonoylglycerol A Novel Inhibitor of Androgen-Independent Prostate Cancer Cell Invasion (full - 2004) http://cancerres.aacrjournals.org/cgi/content/full/64/24/8826?ijkey=951f5f9d238bdf059cf30ee2be3a5a31aa f2b094
146

A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells. (full – 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450257/?tool=pubmed

Cannabinoid Receptor as a Novel Target for the Treatment of Prostate Cancer (full - 2005) http://cancerres.aacrjournals.org/cgi/reprint/65/5/1635.pdf

Cannabinoid Receptor Agonist-induced Apoptosis of Human Prostate Cancer Cells LNCaP Proceeds through Sustained Activation of ERK1/2 Leading to G1 Cell Cycle Arrest (full - 2006) http://www.jbc.org/content/281/51/39480.full

Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism (full – 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565646/?tool=pubmed

US Patent Application 20070041994 - Compositions and methods for treating prostate disorders ( full – 2007) http://www.patentstorm.us/applications/20070041994/fulltext.html

Cannabinoid receptors agonist WIN-55,212-2 inhibits angiogenesis, metastasis and tumor growth of androgen-sensitive prostate cancer cell CWR22R{nu}1 xenograft in athymic nude mice (abst - 2007)

http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2007/1_Annual_Meeting/2195?maxtosh ow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=720&resourcety pe=HWCIT

Endocannabinoids in endocrine and related tumours (full - 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)- Methanandamide and JWH-015: Involvement of CB2 (full - 2009) http://www.nature.com/bjc/journal/v101/n6/full/6605248a.html

The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19908944

Active Chemicals in Cannabis Inhibits Prostate Cancer Cell Growth (news - 2009)

http://www.elements4health.com/active-chemicals-in-cannabis-inhibits-prostate-cancer-cell-growth.html

Cannabis is linked to a 'cancer cure'. (news – 2009)

http://www.thefreelibrary.com/Cannabis+is+linked+to+a+'cancer+cure'+HEALTH.-a0206081618

Cannabis chemicals may help fight prostate cancer (news - 2009)

http://www.reuters.com/article/healthNews/idUSTRE57I02Z20090819

Chemicals in cannabis found to stop prostate cancer (news - 2009)

http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2009m8d19-Chemicals-in- cannabis-found-to-stop-prostate-cancer
147

Active cannabis chemicals halt prostate cancer cell growth (news - 2009)

http://www.news-medical.net/news/20090908/Active-cannabis-chemicals-halt-prostate-cancer-cell- growth.aspx

Cannabis may apparently stop prostate cancer growth (news - 2009)

http://www.healthjockey.com/2009/08/21/cannabis-may-apparently-stop-prostate-cancer-growth/

Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed

Cannabis chemicals may help fight prostate cancer (news - 2010)

http://www.abbotsfordtimes.com/entertainment/movie- guide/Cannabis+chemicals+help+fight+prostate+cancer/1908592/story.html?id=1908592#Comments

The endocannabinoid system and cancer: therapeutic implication (full – 2011)

http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01327.x/full

The endocannabinoid system in prostate cancer. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21912423

Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21995886

Cannabinoid Receptor Type 1 (CB1) Activation Inhibits Small GTPase RhoA Activity and Regulates Motility of Prostate Carcinoma Cells. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22087025

Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22110202

The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/20838378

Cannabinoid Receptor Type 1 (CB1) Activation Inhibits Small GTPase RhoA Activity and Regulates Motility of Prostate Carcinoma Cells. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22087025

CANCER - RHABDOMYOSARCOMA

Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma (full - 2009) http://mct.aacrjournals.org/content/8/7/1838.full
148

CANCER - RISK CANNABIS VS TOBACCO


So, you thought it was the tar that caused cancer... (news - no date)

http://www.ukcia.org/research/cancer2.php

Marijuana Less Harmful to Lungs than Cigarettes (news - 1994)

http://www.ukcia.org/research/lungs.php

Premiere British Medical Journal Pronounces Marijuana Safer Than Alcohol, Tobacco (news - 1998) http://cannabislink.ca/medical/safer.html

Why Doesn't Smoking Marijuana Cause Cancer? (news - 1999)

http://www.healthcentral.com/drdean/408/14275.html

Cannabis and tobacco smoke are not equally carcinogenic (full - 2005)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1277837

Smoking Marijuana Does Not Cause Lung Cancer (news - 2005)

http://www.mapinc.org/drugnews/v05/n1065/a03.html

Cannabis Smoke Is Less Likely To Cause Cancer Than Tobacco Smoke

http://www.sciencedaily.com/releases/2005/10/051019003339.htm

Blunt Smokers Link Dependence Potential To Nicotine (news - 2006)

http://www.medicalnewstoday.com/articles/52838.php

Marijuana Smoking Found Non-Carcinogenic (news - 2006)

http://www.medpagetoday.com/HematologyOncology/LungCancer/tb/3393

Cannabis Smoke and Cancer: Assessing the Risk (news - 2008)

http://www.norml.org/index.cfm?Group_ID=6891

(news - 2005)
Hypothesizing that marijuana smokers are at a significantly lower risk of carcinogenicity

relative to tobacco-non-marijuana smokers: evidenced based on statistical reevaluation of

current literature. (full - 2008)

http://www.thefreelibrary.com/Hypothesizing+that+marijuana+smokers+are+at+a+significantly+lower...- a0196052086

CANCER - SKIN

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors (full - 2003) http://www.jci.org/cgi/content/full/111/1/43?ijkey=MpUgjDbqHybAU
149

Starting Point Of Sun-Induced Skin Cancer Discovered: Molecular 'Hooks' Also Pull Compounds From Marijuana From Bloodstream (news - 2008) http://www.sciencedaily.com/releases/2008/05/080515072642.htm

U of Minnesota researcher discovers the starting point of sun-induced skin cancer
(news – 2008) http://www.bio-medicine.org/medicine-news-1/U-of-Minnesota-researcher-discovers-the-starting-point-of- sun-induced-skin-cancer-19419-1/

Cannabis Science Provides Physician‘s Documentation That Confirms Successful Treatment of Skin Cancer (news/ info-mercial – 2011) http://www.businesswire.com/news/home/20110406006516/en/Cannabis-Science- Physician%E2%80%99s-Documentation-Confirms-Successful-Treatment

CANCER – SQUAMOUS CELL CARCINOMA

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors (full – 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151833/

Marijuana use and Risk of Oral Squamous Cell Carcinoma (full - 2004)

http://cancerres.aacrjournals.org/content/64/11/4049.full

Peripheral Cannabinoids Attenuate Carcinoma Induced Nociception in Mice (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771220/

A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma. (abst - 2009) http://cancerpreventionresearch.aacrjournals.org/cgi/content/abstract/2/8/759

Effects of Cannabinoids on Oral Squamous Cell Carcinoma Proliferation (abst – 2009) http://iadr.confex.com/iadr/2009miami/webprogram/Paper120589.html

Cannabis Oil Shrinks ―One Of The Worst‖ Cancers (news – infomercial – 2012) (warning: graphic photos) http://cannabiscureuk.wordpress.com/2012/01/11/breaking-news-cannabis-science-inc-cannabis-oil- shrinks-one-of-the-worst-cancers/
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 151 - 155

CANCER - TESTICULAR


Chemotherapy for Testicular Cancer (anecdotal - no date)

http://www.rxmarihuana.com/shared_comments/testicularchemo.htm

Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy (abst- 1986) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=127

CANCER - THYMOMA

A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cell (abst- 2008) http://www.greenmedinfo.com/article/cannabinoids-may-have-therapeutic-role-play-treating-thyoma

CANCER - THYROID

Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth (full - 2001) http://www.fasebj.org/cgi/reprint/15/14/2745?ijkey=1b6e92836655dd275d36c82a7957423ec2106c6a

Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis1 (full - 2003) http://www.fasebj.org/cgi/reprint/17/12/1771

A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. (full – 2006) http://www.fasebj.org/content/early/2004/10/02/fj.04-1754fje.long

Endocannabinoids in endocrine and related tumours (full - 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma. (abst - 2008) http://www.unboundmedicine.com/medline/ebm/record/18197164/full_citation/Cannabinoid_2_receptor_in duction_by_IL_12_and_its_potential_as_a_therapeutic_target_for_the_treatment_of_anaplastic_thyroid_ca rcinoma_

A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19189054/abstract/A_metabolically_stable_analog ue_of_anandamide_Met_F_AEA_inhibits_human_thyroid_carcinoma_cell_lines_by_activation_of_apopto sis_
151

CANCER - VARIOUS/ UNNAMED

Unpublished Federal Study Found THC-Treated Rats Lived Longer, Had Less Cancer (news - no date)
http://www.drugsense.org/mcwilliams/www.marijuanamagazine.com/toc/rats.htm
Analgesic effect of delta-9-tetrahydrocannabinol. (abst - 1975)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=16

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=17

(abst - 1975)
Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo. (abst - 1979) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=5

Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate A prospective, randomized evaluation (abst - 1979) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=23

Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy; a double-blind cross-over trial against placebo (abst - 1979) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=27

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-- tetrahydrocannabinol. (abst - 1979) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=107

Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. (abst - 1979) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=126

The antiemetic activity of tetrahydrocanabinol versus metoclopramide and thiethylperazine in patients undergoing cancer chemotherapy. (abst - 1980) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=24

A multi-institutional Phase III study of nabilone vs. placebo in chemotherapy-induced nausea and vomiting. (abst - 1982) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=156

Prospective randomized double-blind trial of nabilone versus domperidone in the

treatment of cytotoxic-induced emesis (abst - 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=129
152

Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy (abst - 1988) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=31

Dronabinol enhancement of appetite in cancer patients. (abst - 1990)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=149

Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy- induced nausea and vomiting. (abst - 1991) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=28

A phase II study of delta-9-tetrahydrocannabinol for appetite stimulation in cancer- associated anorexia (abst -1994) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=52

NTP Technical Report on the Toxicology and Carcinogenesis Studies of 1-Trans-Delta9- Tetrahyrdocannabinol (CAS No. 1972-08-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies) (full - 1996) http://www.druglibrary.org/Schaffer/hemp/Trans-Delta Report.pdf

Toxicity and Carcinogenicity of {Delta}9-Tetrahydrocannabinol in Fischer Rats and B6C3F1 Mice (abst - 1996) http://toxsci.oxfordjournals.org/cgi/content/abstract/30/1/109?maxtoshow=&hits=80&RESULTFORMAT= &fulltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT

Study: THC Not Cancer-Causing (news - 1997) http://www.ukcia.org/research/cancer.php Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors (full - 2000)

http://www.jbc.org/content/275/41/31938.full

Therapeutic Aspects of Cannabis and Cannabinoids (full - 2001)

http://bjp.rcpsych.org/cgi/reprint/178/2/107.pdf
Anti-Tumor Effects (news - 2001) http://www.ukcia.org/research/AntiTumorEffects.htm

Targeting the endocannabinoid system in cancer therapy: A call for further research (full - 2002) http://www.fuoriluogo.it/medicalcannabis/documenti/bifulco2002.pdf
Patent 6410588 Use of cannabinoids as anti-inflammatory agents

http://www.patentstorm.us/patents/6410588/fulltext.html

Endocannabinoids in the immune system and cancer. (abst - 2002)

http://www.ncbi.nlm.nih.gov/pubmed/12052046

Cannabinoids: Potential Anticancer Agents (full - 2003)

http://americanmarijuana.org/Guzman-Cancer.pdf

Inhibition of tumor angiogenesis by cannabinoids (full - 2003)

(full – 2002)
http://www.fasebj.org/cgi/reprint/02-0795fjev1?ijkey=93a5d281f850b12428c0ce7239c7af67fe8fab6f
153

Established and potential therapeutic applications of cannabinoids in oncology (abst + intro - 2003) http://www.springerlink.com/content/py9cunbm343und5v/

The effects of smoked cannabis in painful peripheral neuropathy (abst - 2003)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=96

Therapeutic potential of cannabinoids in CNS disease. (abst - 2003)

http://www.ncbi.nlm.nih.gov/pubmed/12617697

Cannabinoid receptor systems: therapeutic targets for tumour intervention (abst - 2003) http://informahealthcare.com/doi/abs/10.1517/14728222.7.6.749

Cannabis May Help Combat Cancer-causing Herpes Viruses (news - 2004)

http://www.sciencedaily.com/releases/2004/09/040923092627.htm

THC in marijuana may block the spread of forms of cancer causing herpes viruses (news - 2004) http://www.news-medical.net/news/2004/09/22/4990.aspx

Cancer Killer (news - 2004) http://www.november.org/stayinfo/breaking2/CancerKiller.html Medicinal Cannabis in Oncology Practice: Still a Bridge Too Far? (full – 2005)

http://jco.ascopubs.org/content/23/13/2886.full.pdf+html

Involvement of Cannabinoids in Cellular Proliferation (full - 2005)

http://www.bentham.org/mrmc/sample/mrmc5-1/0008N.pdf

Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study (full - 2006) http://cebp.aacrjournals.org/content/15/10/1829.full

The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells. (full - 2006)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WWK-4JP3G9H- 8&_user=10&_coverDate=04%2F30%2F2006&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sor t=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=3d4033 9063a535f66fd180bef7aac1e9&searchtype=a

Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-In- Cachexia-Study-Group. (full - 2006) http://jco.ascopubs.org/content/24/21/3394.long

Cannabinoids and cancer: pros and cons of an antitumour strategy (full - 2006)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617062/?tool=pmcentrez

Cannabinoids As Cancer Hope (article - 2006)

http://www.norml.org/index.cfm?Group_ID=6814
154

The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=177

Different views on the association between cannabinoids and cancer (abst - 2006)

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=16835997&dopt=abstrac tplus

Cannabinoids Halt Pancreatic Cancer, Breast Cancer Growth, Studies Say (news - 2006)

http://www.thehempire.com/index.php/cannabis/news/cannabinoids_halt_pancreatic_cancer_breast_cancer _growth_studies_say

Marijuana Smoking Found Non-Carcinogenic (news - 2006)

http://www.medpagetoday.com/HematologyOncology/LungCancer/tb/3393

Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full - 2007) http://jnci.oxfordjournals.org/cgi/content/full/100/1/59

A Cannabinoid Anticancer Quinone, HU-331, Is More Potent and Less Cardiotoxic Than Doxorubicin: A Comparative in Vivo Study (full - 2007) http://jpet.aspetjournals.org/content/322/2/646.full

Sativex: Fact Sheet (full - 2007)

http://www.bayer.ca/files/sativex_fs_fd_109461_e _GW_.pdf

Sativex: Health Care Professional letter (letter - 2007)

http://www.bayer.ca/files/sativex_dhcpl_lapds_109461_e _GW_-2.pdf

Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion (Review) (abst- link to full PDF – 2007) http://www.spandidos-publications.com/or/17/4/813

A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/12749972

Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor- suppressor efficacy. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/17192847

Science: The use of cannabis does not influence the efficacy of two anti-cancer drugs, a clinical study finds (news - 2007) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=242#2

No Decrease in Pulmonary Function Associated with Long-Term Cannabis Smoking, Study Says (news - 2007) http://www.illinoisnorml.org/content/view/366/27/

Nabilone relieves many advanced Ca symptoms (news - 2007)

http://findarticles.com/p/articles/mi_hb4365/is_9_40/ai_n29428135/?tag=content;col1
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 156 - 160

Cannabinoids May Inhibit Cancer Cell Invasion (news - 2007)

http://www.sciencedaily.com/releases/2007/12/071226004546.htm

Marijuana could suppress Tumor Cell Growth (news - 2007)

http://www.healthjockey.com/2007/12/29/marijuana-could-suppress-tumor-cell-growth/

Cannabinoids for Cancer Treatment: Progress and Promise (full - 2008)

http://cancerres.aacrjournals.org/cgi/content/full/68/2/339

Hypothesizing that marijuana smokers are at a significantly lower risk of carcinogenicity

relative to tobacco-non-marijuana smokers: evidenced based on statistical reevaluation of

current literature. (full - 2008)

http://www.thefreelibrary.com/Hypothesizing+that+marijuana+smokers+are+at+a+significantly+lower...- a0196052086

Endocannabinoids in endocrine and related tumours (full - 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

Nabilone for the treatment of paraneoplastic night sweats: a report of four cases (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/18715188

Science: Nabilone effective in the treatment of night sweats of four patients with advanced cancer (news – 2008) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=277#1

Cannabis Smoke and Cancer: Assessing the Risk (news - 2008)

http://www.norml.org/index.cfm?Group_ID=6891

How Cannabis Compares to other treatments (news - 2008)

http://dcsafeaccess.org/medical/how-cannabis-compares-to-other-treatments/

Marijuana May Prevent Cancer, Not Cause It (news - 2008)

http://www.entheology.org/edoto/anmviewer.asp?a=293&print=yes

Changes in the Endocannabinoid System May Give Insight into new and Effective Treatments for Cancer (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791688/?tool=pmcentrez

Cannabinoids as novel anti-inflammatory drugs. (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/?tool=pubmed

TRB3 links ER stress to autophagy in cannabinoid antitumoral action
(abst + link to full PDF - 2009) http://www.landesbioscience.com/journals/autophagy/article/9508

Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19285265

Cannabinoids in the treatment of cancer (abst - 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19442435
156

Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19285265

Hexahydrocannabinols, novel synthetic cannabinoid derivatives, suppress the tumor growth by inhibiting the VEGF secretion and angiogenesis (abst - 2009) http://www.fasebj.org/cgi/content/meeting_abstract/23/1_MeetingAbstracts/761.3?maxtoshow=&hits=10& RESULTFORMAT=&fulltext=cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspe c=relevance&resourcetype=HWCIT

A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma. (abst - 2009) http://cancerpreventionresearch.aacrjournals.org/cgi/content/abstract/2/8/759

Cannabinoid receptor ligands as potential anticancer agents--high hopes for new therapies? (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19589225?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa nel.Pubmed_RVDocSum&ordinalpos=14
Cannabis Compounds have "Palliative" and "Curative" Effects on Cancer

http://www.illinoisnorml.org/content/view/1013/27/

Could smoking pot cut risk of head, neck cancer? (news - 2009)

http://www.health.am/cr/more/could-smoking-pot-cut-risk-of-head-neck-cancer/

NEW USE FOR CANNABINOID-CONTAINING PLANT EXTRACTS Patent application number: 20100249223 (full - 2010) http://www.faqs.org/patents/app/20100249223

(news - 2009)
US Patent Application 20100204312 - METHODS AND COMPOSITIONS FOR TREATING CANCER (full - 2010) http://www.patentstorm.us/applications/20100204312/fulltext.html

Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19896326

Targeting the Endocannabinoid System for the Treatment of Cancer - A Practical View. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20370711?dopt=Abstract

Cannabis-derived substances in cancer therapy--an emerging anti-inflammatory role for the cannabinoids. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20925645

Antitumorigenic Effects of Cannabinoids beyond Apoptosis (abst - 2010)

http://jpet.aspetjournals.org/content/332/2/336.abstract

Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19914218
157

Vets use hemp seed oil on animals with cancer (news - 2010)

http://www.examiner.com/x-33448-LA-County-Environmental-News-Examiner~y2010m3d22-Vets-use- hemp-seed-oil-on-animals-with-cancer

Cannabis Rx: Cutting Through the Misinformation : Dr. Andrew Weil (news - 2010) http://www.huffingtonpost.com/andrew-weil-md/can-cannabis-treat-cancer_b_701005.html

Update on the endocannabinoid system as an anticancer target. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21244344

Intrathecal Administration of the Cannabinoid 2 Receptor Agonist JWH015 Can Attenuate Cancer Pain and Decrease mRNA Expression of the 2B Subunit of N-Methyl- d-Aspartic Acid (abst – 2011)

http://www.anesthesia- analgesia.org/content/early/2011/04/25/ANE.0b013e31821d1062.abstract?maxtoshow=&hits=80&RESUL TFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWC IT

The endocannabinoid system and cancer: therapeutic implication (abst – 2011)

http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01327.x/abstract

Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21432910/abstract/Arachidonoyl_ethanolamide__ AEA__induced_apoptosis_is_mediated_by_J_series_prostaglandins_and_is_enhanced_by_fatty_acid_ami de_hydrolase__FAAH__blockade_

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21175579/abstract/Effects_of_cannabinoids_and_c annabinoid_enriched_Cannabis_extracts_on_TRP_channels_and_endocannabinoid_metabolic_enzymes_

Ingredient in cannabis restores taste for cancer patients (news – 2011)

http://news.yahoo.com/s/afp/20110222/hl_afp/healthdiseasecancerdrugscannabisfood

Worth Repeating: You Can‘t Censor Cannabis Cancer Treatment (news – 2011)

http://www.tokeofthetown.com/2011/03/worth_repeating_you_cant_censor_cannabis_cancer_tr.php#more

The Illegal Herb that Fights Cancer (news - 2011)

http://www.cannabisculture.com/v2/node/27122

Another Study Confirms Anti-Cancer Effects of THC and CBD (news – 2011)

http://www.examiner.com/medical-marijuana-in-philadelphia/another-study-confirms-anti-cancer-effects- of-thc-and-cbd-1

Why doesn‘t marijuana cause cancer? (news – 2011)

http://www.examiner.com/drug-policy-in-reno/why-doesn-t-marijuana-cause-cancer
158

Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21432910

CANNABICHROMENE/ CBC - phytocannabinoid, unknown receptor

Constituents of Cannabis sativa L. VIII: Possible biological application of a new method to separate cannabidiol and cannabichromene. (abst - 1975) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=1151651&dopt=abstract plus

Biological activity of cannabichromene, its homologs and isomers. (abst - 1981)

http://www.ncbi.nlm.nih.gov/pubmed/7298870?dopt=Abstract

Process for preparing cannabichromene (full - 1982)

http://www.patentstorm.us/patents/4315862/description.html

Neurobehavioral actions of cannabichromene and interactions with delta 9- tetrahydrocannabinol. (abst – 1983) http://www.ncbi.nlm.nih.gov/pubmed/6301931

Allergenic properties of naturally occurring cannabinoids. (abst - 1983)

http://www.ncbi.nlm.nih.gov/pubmed/6620158

Neurobehavioral actions of cannabichromene and interactions with delta 9- tetrahydrocannabinol. (abst - 1983) http://www.ncbi.nlm.nih.gov/pubmed/6301931

Intraocular pressure, ocular toxicity and neurotoxicity after administration of delta 9- tetrahydrocannabinol or cannabichromene. (abst – 1984) http://www.ncbi.nlm.nih.gov/pubmed/6323206

Antiinflammatory and antimicrobial compounds and compositions United States Patent 4837228 (full - 1989) http://www.freepatentsonline.com/4837228.html

In vitro metabolism of cannabichromene in seven common laboratory animals. (abst – 1990) http://www.ncbi.nlm.nih.gov/pubmed/1981514

Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. (full - 2008)

http://www.cannabisasmedicine.com/story/antibacterial-cannabinoids-cannabis-sativa- structure%E2%88%92activity-study

Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765124/?tool=pubmed
159

TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action. (full – 2009)

http://www.landesbioscience.com/journals/autophagy/SalazarAUTO5-7.pdf

Antidepressant-like effect of Delta(9)-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866040/?tool=pubmed

Disposition of Cannabichromene, Cannabidiol, and Δ9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High- Performance Liquid Chromatography-Tandem Mass Spectrometry (abst - 2010) http://www.ingentaconnect.com/content/pres/jat/2010/00000034/00000008/art00012

Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ9-tetrahydrocannabinol (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20619971

The endocannabinoid system and cancer: therapeutic implication (full – 2011)

http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01327.x/full

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21175579/abstract/Effects_of_cannabinoids_and_c annabinoid_enriched_Cannabis_extracts_on_TRP_channels_and_endocannabinoid_metabolic_enzymes_

Cannabis Science Reports: National Cancer Institute Updates Confirm Successful Cancer Treatments with Medical Cannabis. (news - 2011) http://www.thefreelibrary.com/Cannabis+Science+Reports:+National+Cancer+Institute+Updates+Conf irm...-a0252875363

The intersection between cannabis and cancer in the United States. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/22019199

Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/20942863/abstract/Non_psychoactive_cannabinoid s_modulate_the_descending_pathway_of_antinociception_in_anaesthetized_rats_through_several_mechani sms_of_action_
Cannabinoids in children (abst – 2011)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=295

CANNABIDIOL/ CBD GPR – 55 agonist, antagonist of CB1 and CB2

ACCESSING 0.5 to 2.0 GRAMS CBD FRACTIONATING THE

PHYTOCANNABINOIDS BY THEIR VAPORIZATION POINTS

http://forum.grasscity.com/medical-marijuana/610429-need-cbd.html

(article - no date )
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 161 - 165

Effects of cannabidiol derivatives on intestinal motility (abst - no date)

http://www.docstoc.com/docs/26071658/Effects-of-cannabidiol-derivatives-on-intestinal-motility-

STUDIES ON THE PHARMACOLOGY AND ACUTE TOXICITY OF COMPOUNDS WITH MARIHUANA ACTIVITY (abst - 1946) http://jpet.aspetjournals.org/content/88/2/154.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Some actions of delta-1 tetrahydrocannabinol and cannabidiol at cholinergic junctions. (full – 1971) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1703324/pdf/brjpharm00552-0217.pdf

A metabolic interaction in vivo between cannabidiol and Δ1-tetrahydrocannabinol (full - 1972) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1666148/?tool=pubmed

Interactions in man of delta-9-tetrahydrocannabinol. II. Cannabinol and cannabidiol. (abst – 1975) http://www.ncbi.nlm.nih.gov/pubmed/1097148

Differential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats. (abst - 1975) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=1237925&dopt=abstract plus

Constituents of Cannabis sativa L. VIII: Possible biological application of a new method to separate cannabidiol and cannabichromene. (abst - 1975) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=1151651&dopt=abstract plus

The influence of delta9-tetrahydrocannabinol, cannabinol and cannabidiol on tissue oxygen consumption. (abst – 1975) http://www.ncbi.nlm.nih.gov/pubmed/1197914

Absence of interaction between delta9-tetrahydrocannabinol (delta-THC) and cannabidiol (CBD) in aggression, muscle control and body temperature experiments in mice.
(abst – 1975) http://www.ncbi.nlm.nih.gov/pubmed/1171491

Anticonvulsant activity of four oxygenated cannabidiol derivatives. (abst – 1975)

http://www.ncbi.nlm.nih.gov/pubmed/1188178

Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol. (abst - 1976)

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=1085130&dopt=abstract plus

Cannabidiol--antiepileptic drug comparisons and interactions in experimentally induced seizures in rats. (abst - 1977) http://jpet.aspetjournals.org/content/201/1/26.abstract?ijkey=8457ace5313942358e64d156c12d04bd3c7d5f 21&keytype2=tf_ipsecsha

In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas. (abst - 1977) http://www.ncbi.nlm.nih.gov/pubmed/616322
161

Interaction of cannabidiol and alcohol in humans. (abst – 1979)

http://www.ncbi.nlm.nih.gov/pubmed/120541

CHRONIC ADMINISTRATION OF CANNABIDIOL TO HEALTHY VOLUNTEERS AND EPILEPTIC PATIENTS (full - 1980) http://web.acsalaska.net/~warmgun/es201.html

Sedative activity of cannabis in relation to its delta'-trans-tetrahydrocannabinol and cannabidiol content. (full - 1981) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071638/?tool=pmcentrez

Antiepileptic potential of cannabidiol analogs. (abst - 1981)

http://www.ncbi.nlm.nih.gov/pubmed/7298873

The cannabinoids as potential antiepileptics. (abst - 1981)

http://www.ncbi.nlm.nih.gov/pubmed/6975285

Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice. (abst - 1982) http://www.ncbi.nlm.nih.gov/pubmed/6129147

Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs. (abst - 1982) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=7071126&dopt=abstract plus

Allergenic properties of naturally occurring cannabinoids. (abst - 1983)

http://www.ncbi.nlm.nih.gov/pubmed/6620158

Ocular Hypotension, Ocular Toxicity, and Neurotoxicity in Response to Marihuana Extract and Cannabidiol. (abst - 1984) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=6098513&dopt=abstract plus

Stimulation of Sphingomyelin Hydrolysis by Cannabidiol in Fibroblasts from a Niemann- pick Patient. (abst - 1984) http://medical-journals.healia.com/doc/6732800/Stimulation-of-sphingomyelin-hydrolysis-by-cannabidiol- in-fibroblasts-from-a-Niemann-Pick-patient

Treatment of Meige's syndrome with cannabidiol. (abst - 1984)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=114

The quasi-morphine withdrawal syndrome: effect of cannabinol, cannabidiol and tetrahydrocannabinol. (abst - 1985) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=2994117&dopt=abstract plus

Beneficial and adverse effects of cannabidiol in a Parkinson patient with sinemet-induced

dystonic dyskinesia. (abst - 1985)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=142
162

Open label evaluation of cannabidiol in dystonic movement disorders. (full - 1986)

http://web.acsalaska.net/~warmgun/es017.html

EFFECTS OF CANNABIDIOL IN HUNTINGTON'S DISEASE (abst - 1986)

http://www.druglibrary.org/schaffer/hemp/medical/hunting1.htm

Cannabidiol in dystonic movement disorders. (abst - 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=139

The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation. (abst - 1989) http://www.ncbi.nlm.nih.gov/pubmed/2575149

Antianxiety effect of cannabidiol in the elevated plus-maze. (abst – 1990)

http://www.ncbi.nlm.nih.gov/pubmed/1969666

Mammary excretion of cannabidiol in rabbits after intravenous administration.
(abst - 1994) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=7897602&dopt=abstract plus

Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
(full - 1998) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=20965&tool=pmcentrez

Marijuana chemical tapped to fight strokes ? (news - 1998)

http://findarticles.com/p/articles/mi_m1200/is_n2_v154/ai_20973037/?tag=content;col1

Cannabinoid Antioxidant Protects Brain Cells -- Without the High (news – 1998)

http://hempworld.com/HempPharm/articles/medicalm05.html

Cannabinoids might reduce spasticity in multiple sclerosis (full - 2000)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1117698/?tool=pmcentrez

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis (full - 2000) http://www.pnas.org/cgi/content/full/97/17/9561

Advantages of polypharmaceutical herbal cannabis compared to single ingredient, synthetic tetrahydrocannabinol (full - 2000) http://www.cannabis-science.com/papers/cannabis terpenes.pdf
Variations of D9-THC content in single plants of hemp varieties

http://www.ukcia.org/research/VariationOfTHCContent.pdf

Neuroprotective Antioxidants from Marijuana (abst – 2000)

(full - 2000)
http://onlinelibrary.wiley.com/doi/10.1111/j.1749- 6632.2000.tb06193.x/abstract;jsessionid=2FC02E954345A713B5843BEE89616F4F.d02t01
163

Different effects of nabilone and cannabidiol on binocular depth inversion in Man. (abst – 2000) http://www.ncbi.nlm.nih.gov/pubmed/10837858

Synthesis of a primary metabolite of cannabidiol. (abst – 2000)

http://www.ncbi.nlm.nih.gov/pubmed/11029195

Cannabinoids in clinical practice. (abst - 2000)

http://www.ncbi.nlm.nih.gov/pubmed/11152013

Marijuana Extract Helps Arthritis Pain (news - 2000)

http://www.prohealth.com//library/showArticle.cfm?libid=552

Cannabinoid effects on anxiety-related behaviours and hypothalamic neurotransmitters. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11566149

Composition of the essential oils and extracts of two populations of Cannabis sativa L. ssp. spontanea from Austria (full - 2003) http://findarticles.com/p/articles/mi_qa4091/is_/ai_n9299539

Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573773/?tool=pmcentrez

Cannabis and the brain. (full - 2003) http://brain.oxfordjournals.org/cgi/content/full/126/6/1252

Post-ischemic Treatment with Cannabidiol Prevents Electroencephalographic Flattening, Hyperlocomotion and Neuronal Injury in Gerbils. (abst – 2003) http://www.sciencedirect.com/science/article/pii/S030439400300569X

Neuroprotective Effect of(−)Δ9-Tetrahydrocannabinol and Cannabidiol in N-Methyl-d- Aspartate-Induced Retinal Neurotoxicity - Involvement of Peroxynitrite (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892413/?tool=pmcentrez

Therapeutic potential of cannabinoids in CNS disease. (abst - 2003)

http://www.ncbi.nlm.nih.gov/pubmed/12617697

Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells. (abst - 2003) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=14692532&dopt=abstrac tplus

Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/14644587

Anti-tumor effects of cannabidiol, a non-psychotropic cannabinoid, on human glioma cell lines (abst - 2003) http://www.hempworld.com/HempPharm/articles/milanstudy.html

Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 ̳N of 1‘ studies (full - 2004) http://www.ukcia.org/research/InitialExperiencesChronicPain.pdf
164

Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on β-amyloid-induced toxicity in PC12 cells (full - 2004) http://www3.interscience.wiley.com/cgi-bin/fulltext/118757302/HTMLSTART

Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism. (abst – 2004) http://www.ncbi.nlm.nih.gov/pubmed/15640760

Cannabidiol Preserves Retinal Neurons and Reduces Vascular Permeability in Experimental Diabetes (abst - 2004) http://abstracts.iovs.org/cgi/content/abstract/45/5/860?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT

Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early- morning behavior in young adults. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15118485?dopt=Abstract

Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol- Induced Neurotoxicity (full - 2005) http://jpet.aspetjournals.org/content/314/2/780.full

Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor- independent mechanism (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576089/?tool=pmcentrez

Cannabidiol Prevents Cerebral Infarction Via a Serotonergic 5-Hydroxytryptamine1A Receptor–Dependent Mechanism (full - 2005) http://stroke.ahajournals.org/cgi/content/full/36/5/1071

Cannabidiol lowers incidence of diabetes in non-obese diabetic mice (full - 2005)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270485/?tool=pmcentrez

Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival. (abst - 2005) http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1618356 0

Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/15910887

Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia. (abst - 2005) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=171

Treatment with CBD in oily solution of drug-resistant paediatric epilepsies. (abst - 2005)
http://www.cannabis- med.org/studies/ww_en_db_study_show.php?s_id=173&&search_pattern=EPILEPSY
165
 

momofthegoons

Vapor Accessory Addict
Staff member
Pages 166 - 170

Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/15837565?dopt=Abstract

Chemicals in Cannabis may help mentally ill (news - 2005)

http://www.news-medical.net/news/2005/06/06/10716.aspx

Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol in Experimental Diabetes (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592672/?tool=pubmed

Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430692/?tool=pubmed

A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. (full - 2006) http://mcforadhd.free.fr/Russo_Tale_of_Two_Cannabinoids_Med_Hypoth_2006.pdf

Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug (full - 2006)

http://www.scielo.br/scielo.php?pid=S0100-879X2006000400001&script=sci_arttext#Text

Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression (full - 2006) http://molpharm.aspetjournals.org/content/70/3/897.long

The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16458258

Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. (abst - 2006)

http://www.ncbi.nlm.nih.gov/pubmed/16844117

Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test. (abst – 2006)

http://www.ncbi.nlm.nih.gov/pubmed/16876926

Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16997463?dopt=Abstract

The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells. (abst - 2006)

http://www.ihop-net.org/UniPub/iHOP/pm/12214911.html?pmid=16909207

The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16389547
166

Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF- kappaB involvement. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16490313

Cannabidiol inhibits tumour growth in leukaemia and breast cancer (news - 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=220#2

Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. (full - 2007) http://mct.aacrjournals.org/content/6/11/2921.long

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9- tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin (full - 2007) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2219532&tool=pmcentrez

Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption (full - 2007) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2228254&tool=pmcentrez

Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression (full - 2007) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2189818&tool=pmcentrez

Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury (full - 2007) http://ajpheart.physiology.org/cgi/content/full/293/6/H3602

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189767/?tool=pubmed

Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism. (full - 2007) http://www3.interscience.wiley.com/cgi-bin/fulltext/118484119/HTMLSTART

Cannabidiol, unlike synthetic cannabinoids, triggers activation of RBL-2H3 mast cells (full – 2007) http://www.jleukbio.org/content/early/2007/03/05/jlb.1206738.full.pdf+html

The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids. (full – 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190019/?tool=pubmed

US Patent Application 20070099987 - Treating or preventing diabetes with cannabidiol (full – 2007) http://www.patentstorm.us/applications/20070099987/fulltext.html

Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance (abst - 2007) http://medical-journals.healia.com/doc/17320118/Repeated-treatment-with-cannabidiol-but-not-Delta9- tetrahydrocannabinol-has-a-neuroprotective-effect-without-the-development-of-tolerance
167

Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/17419758

Cannabidiol--recent advances. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17712814 Who's Afraid of Cannabidiol? (news - 2007)

http://www.counterpunch.org/gardner07142007.html

Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease) (news - 2007) http://www.letfreedomgrow.com/articles/fr070916.htm

Marijuana Compound Shows Promise In Fighting Breast Cancer (news - 2007)

http://www.sciencedaily.com/releases/2007/11/071123211703.htm

Cannabis may stop Breast Cancer from spreading in the Body (news - 2007)

http://www.healthjockey.com/2007/11/21/cannabis-may-stop-breast-cancer-from-spreading-in-the-body/

Cannabis compound cannabidiol CBD 'halts cancer (news - 2007)

http://news.bbc.co.uk/2/hi/health/7098340.stm

Cannabis compound stops spread of breast cancer: researchers (news - 2007)

http://www.cbc.ca/health/story/2007/11/19/cannabis-cancer.html

Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Δ9-tetrahydrocannabinol (full - 2008) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2279017

US Patent Application 20080262099 - Inhibition of Tumour Cell Migration (full – 2008) http://www.patentstorm.us/applications/20080262099/fulltext.html

Mediation of Cannabidiol anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588644/?tool=pmcentrez

Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. (full - 2008)

http://www.cannabisasmedicine.com/story/antibacterial-cannabinoids-cannabis-sativa- structure%E2%88%92activity-study

Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2451037/?tool=pmcentrez

Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation. (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592995/?tool=pubmed

Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action. (full - 2008) http://www.finola.com/CBDreview2008.pdf
168

Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis
(full - 2008) http://bjp.rcpsych.org/cgi/content/full/192/4/306?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=ca nnabinoid&searchid=1&FIRSTINDEX=1200&resourcetype=HWCIT

The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18781980

A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cell (abst - 2008) http://www.greenmedinfo.com/article/cannabinoids-may-have-therapeutic-role-play-treating-thyoma

5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid. (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/18028339

The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent.
(abst - 2008) http://www.unboundmedicine.com/medline/ebm/record/19045957/abstract/The_nonpsychoactive_cannabis _constituent_cannabidiol_is_a_wake_inducing_agent_

Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders.
(abst - 2008) http://www.unboundmedicine.com/medline/ebm/record/18844286/abstract/Cannabidiol_in_medicine:_a_re view_of_its_therapeutic_potential_in_CNS_disorders_

Inhibition of Breast Cancer Aggressiveness by Cannabidiol (abst - 2008)

http://cbcrp.org.127.seekdotnet.com/research/PageGrant.asp?grant_id=4903

Can cannabis offer hope for Alzheimer's? (news - 2008)

http://findarticles.com/p/articles/mi_8002/is_2008_March_11/ai_n38819766/?tag=content;col1

Therapeutic time window of cannabidiol treatment on delayed ischemic damage via high- mobility group box1-inhibiting mechanism. (full – 2009) http://www.jstage.jst.go.jp/article/bpb/32/9/1538/_pdf

Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells (full – 2009) http://www.jbc.org/content/285/3/1616.full?sid=43211ca4-a4aa-4182-a554-d15e2835e288

Non-psychotropic plant cannabinoids:new therapeutic opportunities from an ancient herb (full - 2009 ) http://cannabisinternational.org/info/Non-Psychoactive-Cannabinoids.pdf

Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664885/?tool=pubmed
169

Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765124/?tool=pubmed

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737440/?tool=pubmed

Cannabinoids as novel anti-inflammatory drugs. (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/?tool=pubmed

Cannabidiol, a Nonpsychotropic Component of Cannabis, Inhibits Cue-Induced Heroin Seeking and Normalizes Discrete Mesolimbic Neuronal Disturbances (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829756/?tool=pmcentrez

Cannabidiol As a Putative Novel Therapy for Diabetic Retinopathy: A Postulated Mechanism of Action as an Entry Point for Biomarker-Guided Clinical Development. (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955420/?tool=pubmed

Cannabidiol: a promising drug for neurodegenerative disorders? (full - 2009)

http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5949.2008.00065.x/full

Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682269/

The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function (full – 2009) http://content.karger.com/produktedb/produkte.asp?DOI=000201556&typ=pdf

Cannabidiol-induced lymphopenia does not involve NKT and NK cells. (full–2009) http://www.jpp.krakow.pl/journal/archive/10_09_s3/pdf/99_10_09_s3_article.pdf

Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania (abst – 2009) http://jop.sagepub.com/content/25/2/274.abstract

Cannabidiol Attenuates Myocardial Dysfunction, Fibrosis, Inflammation, Cell Death and Interrelated Signaling Pathways Associated With Diabetic Cardiomyopathy
(abst - 2009)

http://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S868?maxtoshow=&hits =80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1680&resourcetype=HWC IT

Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro- inflammatory cytokines during experimental periodontitis in rats. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19070683

Cannabidiol-2',6'-Dimethyl Ether, a Cannabidiol Derivative, Is a Highly Potent and

Selective 15-Lipoxygenase Inhibitor. (abst - 2009)

http://www.unboundmedicine.com/medline/ebm/record/19406952/abstract/
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Vapor Accessory Addict
Staff member
Pages 171 - 175

Time-dependent vascular actions of cannabidiol in the rat aorta. (abst – 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19285060

Beneficial effects of a Cannabis sativa extract treatment on diabetes-induced neuropathy and oxidative stress. (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19441010/abstract/

Cannabidiol targets mitochondria to regulate intracellular Ca2+ levels. (abst – 2009)

http://www.unboundmedicine.com/medline/ebm/record/19228959/abstract/Cannabidiol_targets_mitochond ria_to_regulate_intracellular_Ca2+_levels_

Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis. (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19690824/abstract/Cannabidiol_a_safe_and_non_p sychotropic_ingredient_of_the_marijuana_plant_Cannabis_sativa_is_protective_in_a_murine_model_of_c olitis_

Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation. (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19596476/abstract/Cannabidiol_ameliorates_cogni tive_and_motor_impairments_in_mice_with_bile_duct_ligation_

Cannabidiol for the treatment of psychosis in Parkinson‘s disease (abst - 2009)

http://jop.sagepub.com/cgi/content/abstract/23/8/979?maxtoshow=&hits=80&RESULTFORMAT=&fulltex t=cannabinoid&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT

Modulation of effective connectivity during emotional processing by Delta9- tetrahydrocannabinol and cannabidiol. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19775500?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pub med_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)- tetrahydrocannabinol in rats. (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19393686

Opposite Effects of Delta-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology. (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19924114/full_citation/Opposite_Effects_of_Delta _9_Tetrahydrocannabinol_and_Cannabidiol_on_Human_Brain_Function_and_Psychopathology_

Cannabis compound can help cells (news – 2009)

http://www.physorg.com/news154280470.html

Cannabis plant extracts could potentially form the basic ingredients for a market-leading diabetes drug (news – 2009) http://www.thefreelibrary.com/Cannabis+plant+extracts+could+potentially+form+the+basic+ingredients...- a0202701009

Marijuana Chemicals Ease MS Symptoms, Review Confirms (news - 2009)

http://www.drugfree.org/uncategorized/marijuana-chemicals-ease-ms
171

Cannabis by product helps reduce effects of Parkinson disease medication
(news - 2009) http://en.mercopress.com/2009/12/30/cannabis-by-product-helps-reduce-effects-of- parkinson-disease-medication/

Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823358/?tool=pubmed

Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845559/?tool=pmcentrez

Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898685/?tool=pmcentrez

Therapeutical use of the cannabinoids in psychiatry (full – 2010)

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516- 44462010000500009&lng=en&nrm=iso&tlng=en

Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925907/?tool=pubmed

Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke (full – 2010)
http://www.mdpi.com/1424-8247/3/7/2197/pdf

Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819831/?tool=pmcentrez

Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936031/?tool=pubmed

Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. (full - 2010) http://www.springerlink.com/content/b81620q7l48h2n51/fulltext.html

Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy (full - 2010) http://www.natap.org/2010/newsUpdates/marijuana.pdf

Antidepressant-like effect of Delta(9)-tetrahydrocannabinol and other cannabinoids

isolated from Cannabis sativa L. (full - 2010)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866040/?tool=pubmed
172

Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5- HT1A receptor activation. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829220/?tool=pubmed

Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation. (abst – 2010) http://www.unboundmedicine.com/medline/ebm/record/21537423/abstract/Diabetic_retinopathy:_Role_of_ inflammation_and_potential_therapies_for_anti_inflammation_

A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice. (abst – 2010) http://www.unboundmedicine.com/medline/ebm/record/19785914/abstract/A_behavioural_comparison_of_ acute_and_chronic_Delta9_tetrahydrocannabinol_and_cannabidiol_in_C57BL/6JArc_mice_

Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors. (abst – 2010) http://www.unboundmedicine.com/medline/ebm/record/20457188/abstract/Intra_dorsal_periaqueductal_gr ay_administration_of_cannabidiol_blocks_panic_like_response_by_activating_5_HT1A_receptors_

Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20884951

Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20668920

Regulation of nausea and vomiting by cannabinoids (abst - 2010)

http://onlinelibrary.wiley.com/doi/10.1111/j.1476- 5381.2010.01176.x/abstract;jsessionid=56CED9CE51B025C161AA2E821BEC94ED.d01t01

Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20590615

Cannabidiol bioavailability after nasal and transdermal application: effect of permeation enhancers. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20545522

Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20884951

Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19914218

Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival (abst - 2010) http://mct.aacrjournals.org/content/9/1/180.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabis&searchid=1&FIRSTINDEX=240&sortspec=date&resourcetype=HWCIT
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Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19729208?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa nel.Pubmed_RVDocSum&ordinalpos=3

Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania. (abst - 2010) http://www.unboundmedicine.com/medline/ebm/record/19939866/full_citation/Effects_of_cannabidiol_on _amphetamine_induced_oxidative_stress_generation_in_an_animal_model_of_mania_

Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis (abst - 2010) http://www.nature.com/npp/journal/vaop/ncurrent/abs/npp201058a.html

Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology (abst - 2010) http://www.nature.com/npp/journal/v35/n3/full/npp2009184a.html

Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20695034

Cannabidiol attenuates delayed-type hypersensitivity reactions via suppressing T-cell and macrophage reactivity. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21042286

Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19896326

Disposition of Cannabichromene, Cannabidiol, and Δ9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High- Performance Liquid Chromatography-Tandem Mass Spectrometry (abst - 2010) http://www.ingentaconnect.com/content/pres/jat/2010/00000034/00000008/art00012

Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20561509

Anticonvulsant effects of GWP42006 in vitro and in vivo in rat (abst - 2010)

http://www.physoc.org/custom2/publications/proceedings/archive/article.asp?ID=Proc Physiol Soc %2019C117

The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic- ischemic brain damage in mice is mediated by CB(2) and adenosine receptors. (abst – 2010)

http://www.unboundmedicine.com/medline/ebm/record/19900555/abstract/The_neuroprotective_effect_of_ cannabidiol_in_an_in_vitro_model_of_newborn_hypoxic_ischemic_brain_damage_in_mice_is_mediated_ by_CB_2__and_adenosine_receptors_
174

Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report (abst - 2010) http://jop.sagepub.com/content/25/1/121

Non-psychoactive cannabis to be unveiled at Annual National Clinical Conference on Cannabis Therapeutics (news - 2010) http://www.news-medical.net/news/20100409/Non-psychoactive-cannabis-to-be-unveiled-at-Annual- National-Clinical-Conference-on-Cannabis-Therapeutics.aspx

Prescription Marijuana Without "Intoxicating" Effect in Research Stage (news - 2010)

http://www.nbclosangeles.com/news/health/Scientists-Aim-to-Make-Marijuana-Perscription-Drug- 108736999.html

Key ingredient staves off marijuana memory loss (news - 2010)

http://www.nature.com/news/2010/101001/full/news.2010.508.html?s=news_rss

Medical Marijuana; The active ingredient in marijuana cuts tumor growth in common

lung cancer in half and significantly reduces the ability of the cancer to spread, say

researchers at Harvard University. (news – 2010)

http://www.thefreelibrary.com/Medical+Marijuana;+The+active+ingredient+in+marijuana+cuts+tumor ...-a0243683610

Pot Compound Mitigates Diabetic Cardiomyopathy (news - 2010)

http://www.norml.org/index.cfm?Group_ID=8424

Cannabinoids inhibit and may prevent neuropathic pain in diabetes. (news - 2010)

http://medigardens.blogspot.com/2010/04/march-2010-cannabinoids-inhibit-and-may.html

Lab Notes: Pot Has Benefits for Diabetic Hearts (news - 2010)

http://www.medpagetoday.com/LabNotes/LabNotes/23853

Cannabidiol (CBD) as an Anti-Arrhythmic – the Role of the CB1 Receptors
(news – 2010) http://cannabisclinicians.org/2011/cannabidiol-cbd-as-an-anti-arrhythmic-the-role-of-the-cb1-receptors/

Key ingredient dilutes marijuana's effect on memory. (news – 2010)

http://www.thefreelibrary.com/Key+ingredient+dilutes+marijuana's+effect+on+memory.-a0238532965

The potential for clinical use of cannabinoids in treatment of cardiovascular diseases. (full – 2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5922.2010.00233.x/pdf

Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936031/?tool=pubmed

Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in

the mouse brain: an intravital microscopy study (full – 2011)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034694/?tool=pmcentrez
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 176 - 180

Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230631/?tool=pubmed

Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimers' disease (full – 2011) http://molpharm.aspetjournals.org/content/early/2011/02/24/mol.111.071290.long

Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full – 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf

Role of Myeloid-Derived Suppressor Cells in Amelioration of Experimental Autoimmune Hepatitis Following Activation of TRPV1 Receptors by Cannabidiol (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069975/?tool=pmcentrez

Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis. (full – 2011) http://www.nature.com/cddis/journal/v2/n6/pdf/cddis201152a.pdf

Cannabidiol, a Major Phytocannabinoid, as a Potent Atypical Inhibitor for Cytochrome P450 2D6. (full – 2011) http://dmd.aspetjournals.org/content/early/2011/08/05/dmd.111.041384.long

Brief Report: Cannabidiol Prevents the Development of Cold and Mechanical Allodynia in Paclitaxel-Treated Female C57Bl6 Mice. (full – 2011) http://www.anesthesia-analgesia.org/content/113/4/947.long

Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232190/?tool=pubmed

Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21704641/abstract/Identification_of_cytochrome_ P450_enzymes_responsible_for_metabolism_of_cannabidiol_by_human_liver_microsomes_

Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent. (abst - 2011)

http://www.unboundmedicine.com/medline/ebm/record/22129319/abstract/Safety_and_Side_Effects_of_C annabidiol_a_Cannabis_sativa_Constituent_

Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/22116907/abstract/17_Cannabidiol_as_an_anti_arr hythmic_the_role_of_the_CB1_receptors_

Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21144973/abstract/Cannabidiol_attenuates_cardiac _dysfunction_oxidative_stress_fibrosis_and_inflammatory_and_cell_death_signaling_pathways_in_diabeti c_cardiomyopathy_
176

The Non-Psychoactive Plant Cannabinoid, Cannabidiol Affects Cholesterol Metabolism- Related Genes in Microglial Cells. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21533611

Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors. (abst - 2011) http://marijuana.researchtoday.net/archive/8/1/3517.htm

Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21182490

Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21771609

Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Study. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21412224

CANNABIDIOL INHIBITS PATHOGENIC T-CELLS, DECREASES SPINAL MICROGLIAL ACTIVATION AND AMELIORATES MULTIPLE SCLEROSIS-LIKE DISEASE IN C57BL/6 MICE. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21449980

Anti-Aversive Effects of Cannabidiol on Innate Fear-Induced Behaviors Evoked by an Ethological Model of Panic Attacks Based on a Prey vs the Wild Snake Epicrates cenchria crassus Confrontation Paradigm. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21918503

Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21870037

Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21243485

Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A) Somatodendritic: Autoreceptors in the Dorsal Raphe Nucleus. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21827451

A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355

Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238476
177

Cannabidiol potentiates Δ(9)-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats.
(abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21667074

Inhibitory Effect of Standardized Cannabis sativa Extract and Its Ingredient Cannabidiol on Rat and Human Bladder Contractility. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21310467

Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21307846

Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21262236

Cannabidiol induces programmed cell death in breast cancer cells by coordinating the crosstalk between apoptosis and autophagy. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21566064

Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22198381

Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/20859676

Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21867717

Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A) Somatodendritic: Autoreceptors in the Dorsal Raphe Nucleus. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21827451

Regulation of nausea and vomiting by cannabinoids. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21175589/abstract/Regulation_of_nausea_and_vo miting_by_cannabinoids_

The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21975813/abstract/The_effects_of_cannabidiolic_a cid_and_cannabidiol_on_contractility_of_the_gastrointestinal_tract_of_Suncus_murinus_

Cannabidiol Dampens Streptozotocin-Induced Retinal Inflammation by Targeting of Microglial Activation (abst - 2011) http://abstracts.iovs.org/cgi/content/abstract/52/6/1002?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT
178

Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive- compulsive behaviour. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21796370

Cannabis with high cannabidiol content is associated with fewer psychotic experiences. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21592732

A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355

Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21798112

Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. (abst – 2011) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=315

Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/22007164/abstract/Endocannabinoid_system_and_ psychiatry:_in_search_of_a_neurobiological_basis_for_detrimental_and_potential_therapeutic_effects_

The endocannabinoid system in the regulation of emotions throughout lifespan: a discussion on therapeutic perspectives. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21693551/abstract/The_endocannabinoid_system_i n_the_regulation_of_emotions_throughout_lifespan:_a_discussion_on_therapeutic_perspectives_

Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and cell death (abst – 2011) http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/639.12?maxtoshow=&hits=80 &RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&sortspec=date&resourcet ype=HWCIT

Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21362471

Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21930120

Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238581

Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia- ischemia in newborn pigs. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21654550
179

Cannabidiol-treated Rats Exhibited Higher Motor Score After Cryogenic Spinal Cord Injury. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21915768

Prospects for cannabinoid therapies in basal ganglia disorders. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21545415

Phytocannabinoids as novel therapeutic agents in CNS disorders (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21924288

Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ(9) -tetrahydrocannabinol in BV-2 microglial cells (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21542829/abstract/Differential_transcriptional_pro files_mediated_by_exposure_to_the_cannabinoids_cannabidiol_and_%CE%94_9___tetrahydrocannabinol _in_BV_2_microglial_cells_

THC and CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis. (abst - 2011) http://www.unboundmedicine.com/medline/ebm/record/21456949/abstract/THC_and_CBD_oromucosal_s pray__Sativex%C2%AE__in_the_management_of_spasticity_associated_with_multiple_sclerosis_

Plasma cannabinoid pharmacokinetics following controlled oral delta9- tetrahydrocannabinol and oromucosal cannabis extract administration. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21078841/abstract/Plasma_cannabinoid_pharmaco kinetics_following_controlled_oral_delta9_tetrahydrocannabinol_and_oromucosal_cannabis_extract_admi nistration_

Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21870037

The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21062637/abstract/The_interplay_of_cannabinoid_ and_NMDA_glutamate_receptor_systems_in_humans:_preliminary_evidence_of_interactive_effects_of_c annabidiol_and_ketamine_in_healthy_human_subjects_

Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22110202

Heterogeneity in the composition of marijuana seized in California. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21288662/abstract/Heterogeneity_in_the_composit ion_of_marijuana_seized_in_California_

Cannabidiol induced a contrasting pro-apoptotic effect between freshly isolated and precultured human monocytes. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/20471992/abstract/Cannabidiol_induced_a_contras ting_pro_apoptotic_effect_between_freshly_isolated_and_precultured_human_monocytes_
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 181 - 185

Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.
(abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21821735/abstract/Cannabidiol_a_major_phytocan nabinoid_as_a_potent_atypical_inhibitor_for_CYP2D6_

A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21492165/abstract/A_synthetic_cannabinoid_CP55 940_inhibits_lipopolysaccharide_induced_cytokine_mRNA_expression_in_a_cannabinoid_receptor_indep endent_mechanism_in_rat_cerebellar_granule_cells_

Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/20942863/abstract/Non_psychoactive_cannabinoid s_modulate_the_descending_pathway_of_antinociception_in_anaesthetized_rats_through_several_mechani sms_of_action_

Cannabidiol (CBD) as an Anti-Arrhythmic (abst – 2011)

http://cannabisclinicians.org/2011/cannabidiol-cbd-as-an-anti-arrhythmic-the-role-of-the-cb1-receptors/

Cannabis could help treat epilepsy #1 (news – 2011)

http://www.newkerala.com/news/world/fullnews-186693.html

Cannabis could be used to treat epilepsy #2 (news – 2011)

http://www.telegraph.co.uk/science/science-news/8440303/Cannabis-could-be-used-to-treat-epilepsy.html

Cannabidiol May Fight Alzheimer's Disease (news - 2011)

http://www.examiner.com/medical-marijuana-in-philadelphia/cannabidiol-may-fight-alzheimer-s- disease?fb_comment=31078356

Marijuana Compound Induces Cell Death In Hard-To-Treat Brain Cancer (news – 2011)
http://www.norml.org/index.cfm?Group_ID=8459

Marijuana Extract Might Help Prevent Chemotherapy-Related Nerve Pain (news – 2011)
http://www.newswise.com/articles/view/580864/?sc=rsmn

Cannabinoid 'Completely' Prevents Chemotherapy-Induced Neuropathy, Study Says (news – 2011) http://www.norml.org/index.cfm?Group_ID=8710

Marijuana component may ease pain from chemo therapy drugs (news – 2011)

http://www.jpost.com/Health/Article.aspx?id=241299

Another Study Confirms Anti-Cancer Effects of THC and CBD (news – 2011)

http://www.examiner.com/medical-marijuana-in-philadelphia/another-study-confirms-anti-cancer-effects- of-thc-and-cbd-1
181

Pot Compound Exerts Anticonvulsant Effects In Animal Models Of Epilepsy (news - 2011) http://www.norml.org/index.cfm?Group_ID=8458

New research provides hope for those with epilepsy (news - 2011)

http://medicalxpress.com/news/2011-04-epilepsy.html

Cannabis Compound Induces Death Of Cells Associated With Liver Fibrosis (news – 2011) http://www.norml.org/index.cfm?Group_ID=8615

Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22231745

CANNABIDIOLIC ACID - precursor to Cannabidiol

Purification and characterization of cannabidiolic-acid synthase from Cannabis sativa L.. Biochemical analysis of a novel enzyme that catalyzes the oxidocyclization of cannabigerolic acid to cannabidiolic acid. (full – 1996) http://www.jbc.org/content/271/29/17411.long

Cannabidiolic acid as a selective cyclooxygenase-2 inhibitory component in cannabis. (full – 2008) http://dmd.aspetjournals.org/content/36/9/1917.long

The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21975813/abstract/The_effects_of_cannabidiolic_a cid_and_cannabidiol_on_contractility_of_the_gastrointestinal_tract_of_Suncus_murinus_

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21175579/abstract/Effects_of_cannabinoids_and_c annabinoid_enriched_Cannabis_extracts_on_TRP_channels_and_endocannabinoid_metabolic_enzymes_

Cannabidiol May Fight Alzheimer's Disease (news – 2011)

http://www.examiner.com/medical-marijuana-in-philadelphia/cannabidiol-may-fight-alzheimer-s-disease

Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22233683

CANNABIGEROL / CBG phytocannabinoid, CB2 agonist

Allergenic properties of naturally occurring cannabinoids. (abst - 1983)

http://www.ncbi.nlm.nih.gov/pubmed/6620158
182

Intraocular pressure, ocular toxicity and neurotoxicity after administration of cannabinol or cannabigerol. (abst – 1984) http://www.ncbi.nlm.nih.gov/pubmed/6499952

Identification of a New Chemotype in Cannabis sativa: Cannabigerol - Dominant Plants, Biogenetic and Agronomic Prospects (abst – 1987) https://www.thieme-connect.com/DOI/DOI?10.1055/s-2006-962705

The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation. (abst - 1989) http://www.ncbi.nlm.nih.gov/pubmed/2575149

A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol. (abst - 1990) http://www.ncbi.nlm.nih.gov/pubmed/1965836

In vitro metabolism of cannabigerol in several mammalian species. (abst – 1990)

http://www.ncbi.nlm.nih.gov/pubmed/2224182

Boron trifluoride etherate on silica-A modified Lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells. (abst - 1998) http://www.ncbi.nlm.nih.gov/pubmed/9875457

Cannabinoids in clinical practice. (abst - 2000)

http://www.ncbi.nlm.nih.gov/pubmed/11152013

Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. (full - 2008) http://www.cannabisasmedicine.com/story/antibacterial-cannabinoids-cannabis-sativa- structure%E2%88%92activity-study

Patent application title: THERAPEUTIC USES OF CANNABIGEROL (full - 2010)

http://www.faqs.org/patents/app/20100292345

Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823359/?tool=pubmed

Antidepressant-like effect of Delta(9)-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866040/?tool=pubmed

Detection of cannabigerol and its presumptive metabolite in human urine after Cannabis consumption. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20614687

Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full – 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf
183

Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21243485

Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive- compulsive behaviour. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21796370

Phytocannabinoids as novel therapeutic agents in CNS disorders (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21924288

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21175579/abstract/Effects_of_cannabinoids_and_c annabinoid_enriched_Cannabis_extracts_on_TRP_channels_and_endocannabinoid_metabolic_enzymes_

CANNABINOID HYPEREMESIS SYNDROME

Cannabinoid hyperemesis: cyclical hyperemesis in association with chronic cannabis abuse (full – 2004) http://gut.bmj.com/content/53/11/1566.full

Cannabinoid hyperemesis: not just a problem in Adelaide Hills (letter – 2005)

http://gut.bmj.com/content/54/5/731.1.full?ijkey=1efc19d4fee30ce0ca73a84272095f5ff8b63736&keytype2 =tf_ipsecsha

"Cannabis hyperemesis" causation questioned. (full – 2006)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1856368/?tool=pubmed

Cannabinoid hyperemesis: marijuana puts patients in hot water. (abst – 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17464661

Cannabinoid hyperemesis relieved by compulsive bathing. (full – 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664574/?tool=pubmed

Cannabinoid hyperemesis. (# 1) (full – 2010)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886568/?tool=pubmed

Cannabinoid Hyperemesis and Compulsive Bathing: A Case Series and Paradoxical Pathophysiological Explanation (full – 2010) http://www.jabfm.org/content/23/6/790.long

Cannabinoid-Induced Hyperemesis: A Conundrum—From Clinical Recognition to Basic

Science Mechanisms (abst/click for full PDF - 2010)

http://www.mdpi.com/1424-8247/3/7/2163/
184

The cannabis hyperemesis syndrome characterized by persistent nausea and vomiting, abdominal pain, and compulsive bathing associated with chronic marijuana use: a report of eight cases in the United States. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20130993

Cannabinoid hyperemesis syndrome as the underlying cause of intractable nausea and vomiting. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21464265

Cannabis Hyperemesis Syndrome. (# 2) (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21692016

Cannabis Hyperemesis Syndrome (# 3) (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/22150623

Image of the month. Skin discoloration from compulsive bathing in a patient with hyperemesis syndrome. (abst – 2011) http://www.cghjournal.org/article/S1542-3565(10)00843-8/abstract

Cannabinoid hyperemesis syndrome inducing acute prerenal failure and electrolyte disturbance. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21877303

Cannabinoid hyperemesis syndrome: literature review and proposed diagnosis and treatment algorithm. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21886087

Cannabinoid hyperemesis syndrome: an underreported entity causing nausea and vomiting of pregnancy. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21170540

Pediatric cannabinoid hyperemesis: two cases. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21131803

Hyperemesis and a High Water Bill. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/22069047

Cannabinoid hyperemesis. (# 4) (abst – 2012)

http://www.ncbi.nlm.nih.gov/pubmed/22186263

Cyclic vomiting syndrome and functional vomiting in adults: association with cannabinoid use in males. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21951771

CANNABINOID RECEPTOR SYSTEM - see ENDOCANNABINOID SYSTEM, CBR
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 186 - 190

CANNABINOR
- synthetic, CB2 agonist

Pharmos Initiates Phase I Trial of CB2-Selective Drug Candidate Cannabinor
(news – 2005) http://www.redorbit.com/news/health/231069/pharmos_initiates_phase_i_trial_of_cb2selective_drug_candi date_cannabinor/index.html

Cannabinoid Receptor Agonist Significantly Reduces Post-Operative Pain, Study Says (news – 2007) http://norml.org/index.cfm?Group_ID=7246

Patent application title: Treatment Of Lower Urinary Tract Dysfunction With CB2- Receptor-Selective Agonists (full – 2009) http://www.faqs.org/patents/app/20090312414

Effects of cannabinor, a novel selective cannabinoid 2 receptor agonist, on bladder function in normal rats. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20207474

Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21168864/abstract/Cannabinor_a_selective_cannab inoid_2_receptor_agonist_improves_bladder_emptying_in_rats_with_partial_urethral_obstruction_

CANNADOR - a phytocannabinoid extract in pill form

A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain management. (full - 2006) http://journals.lww.com/anesthesiology/Fulltext/2006/05000/A_Multicenter_Dose_escalation_Study_of_th e.21.aspx

Analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=184

Cannabis effective at relieving pain after major surgery (news - 2006)

http://www.news-medical.net/news/2006/05/17/17995.aspx

Cannador: Drug from cannabis plant-extract to reduce surgery pain (news - 2006)

http://www.ecofriend.org/entry/cannador-drug-from-cannabis-plant-extract-to-reduce-surgery-pain/

Clinical phase III study with the cannabis extract Cannador successful in multiple

sclerosis (news - 2009)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=300
186

CARDIOVASCULAR - see HEART DISEASE

CARPAL TUNNEL SYNDROME

Use of palmitoylethanolamide in the entrapment neuropathy of the median in the wrist. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21483401

CBR - CB1 CANNABINOID RECEPTOR -activated by THC, Anandamide, synthetics Cannabinoid Receptor Ligands (full - no date)

http://www.tocris.com/pdfs/cannabinoid_receptor_review/page_001.html

Evidence for the presence of cannabinoid CB1 receptors in mouse urinary bladder (abst – 1996) http://pharmgkb.org/pmid/8864542

Cannabinoid-Induced Hypotension and Bradycardia in Rats Is Mediated by CB1-Like Cannabinoid Receptors (full - 1997) http://jpet.aspetjournals.org/content/281/3/1030.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT

Hypoactivity of the Spinal Cannabinoid System Results in NMDA-Dependent Hyperalgesia (full – 1998) http://www.jneurosci.org/content/18/1/451.long

Evidence That the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor (full – 1999) http://www.jbc.org/content/274/5/2794.long

Increased Mortality, Hypoactivity, and Hypoalgesia in Cannabinoid Cb1 Receptor Knockout Mice. (full – 1999) http://www.pnas.org/content/96/10/5780.long

Cannabis and cannabinoids: pharmacology and rationale for clinical use (abst – 1999)

http://pharmgkb.org/pmid/10575283

Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. (abst - 1999) http://www.ncbi.nlm.nih.gov/pubmed/10594647?dopt=Abstract

Thujone exhibits low affinity for cannabinoid receptors but fails to evoke cannabimimetic responses. (abst – 1999) http://www.ncbi.nlm.nih.gov/pubmed/10080239

Endocannabinoids and Vascular Function (full - 2000)

http://jpet.aspetjournals.org/content/294/1/27.long
187

Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1571997/?tool=pmcentrez

Modulation of peristalsis by cannabinoid CB1 ligands in the isolated guinea-pig ileum (full - 2000) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1571902&tool=pmcentrez

Cannabinoid CB1-mediated inhibition of stress-induced gastric ulcers in rats (abst – 2000) http://www.springerlink.com/content/w3jc8rk16k9p92fl/

Inhibition of small intestinal secretion by cannabinoids is CB1 receptor-mediated in rats (abst – 2000) http://www.sciencedirect.com/science/article/pii/S0014299900008438

Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. (abst – 2000) http://www.ncbi.nlm.nih.gov/pubmed/10733937

Association study of a cannabinoid receptor gene (CNR1) polymorphism and schizophrenia (abst – 2000) http://pharmgkb.org/pmid/11204352

Are Cannabinoid Receptor Knockout Mice Animal Models for Schizophrenia?
(abst -2000) http://www.medical-hypotheses.com/article/S0306-9877(00)91261-1/abstract

Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A. (full – 2001) http://www.nature.com/npp/journal/v24/n2/full/1395605a.html

Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572987/?tool=pmcentrez

Endogenous cannabinoids mediate hypotension after experimental myocardial infarction (full - 2001) http://content.onlinejacc.org/cgi/content/full/38/7/2048?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT

2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC31108/

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC55427/?tool=pubmed

Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes. (full – 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572991/?tool=pubmed
188

The Central Cannabinoid Receptor Inactivation Suppresses Endocrine Reproductive Functions. (abst – 2001) http://medical-journals.healia.com/doc/11394887/The-central-cannabinoid-receptor-inactivation- suppresses-endocrine-reproductive-functions

Sourcing the Code: Searching for the Evolutionary Origins of Cannabinoid Receptors, Vanilloid Receptors, and Anandamide (full – 2002) http://www.cannabis-med.org/data/pdf/2002-01-3.pdf

A Peripheral Mechanism for CB1 Cannabinoid Receptor-Dependent Modulation of Feeding (full - 2002) http://www.jneurosci.org/cgi/content/abstract/22/21/9612?ijkey=328b5e83d7be9297b9483d22e0d6319fa0a 862e8&keytype2=tf_ipsecsha

Influence of the CB1 receptor antagonist, AM 251, on the regional haemodynamic effects of WIN-55212-2 or HU 210 in conscious rats (full - 2002) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573379/?tool=pmcentrez

Increased Severity of Stroke in CB1 Cannabinoid Receptor Knock-Out Mice
(full - 2002) http://www.jneurosci.org/cgi/content/full/22/22/9771?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=80&resourcetype=HWCIT#Top

Loss of cannabinoid CB(1) receptors in the basal ganglia in the late akinetic phase of rats with experimental Huntington's disease. (abst – 2002) http://www.ncbi.nlm.nih.gov/pubmed/12709298

The endogenous cannabinoid system controls extinction of aversive memories. (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12152079

Association of a CB1 cannabinoid receptor gene (CNR1) polymorphism with severe alcohol dependence. (abst – 2002) http://www.ncbi.nlm.nih.gov/pubmed/11841893

CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573770/?tool=pmcentrez

The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy (full - 2003) http://jpet.aspetjournals.org/content/307/1/129.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabinoid&searchid=1&FIRSTINDEX=160&resourcetype=HWCIT

The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166293/

Cannabinoid1 receptor in the dorsal vagal complex modulates lower oesophageal sphincter relaxation in ferrets (full – 2003) http://jp.physoc.org/content/550/1/149.full
189

Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon (full – 2003) http://ajpgi.physiology.org/content/286/1/G110.full?sid=fc6948f0-78cf-405c-981b-afaa05ee417c

Association between cannabinoid receptor gene (CNR1) and childhood attention deficit/hyperactivity disorder in Spanish male alcoholic patients (full - 2003) http://www.nature.com/mp/journal/v8/n5/full/4001278a.html

Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis1 (full - 2003) http://www.fasebj.org/cgi/reprint/17/12/1771

High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma (abst – 2003) http://pharmgkb.org/pmid/12970790

Differential distribution of functional cannabinoid CB1 receptors in the mouse gastroenteric tract. (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/12505538

Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor. (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/12568912

Expression of functionally active cannabinoid receptor CB1 in the human prostate gland (abst – 2003) http://onlinelibrary.wiley.com/doi/10.1002/pros.10165/abstract

Structure, expression and regulation of the cannabinoid receptor gene (CB1) in Huntington's disease transgenic mice. (full – 2004) http://onlinelibrary.wiley.com/doi/10.1111/j.1432-1033.2004.04460.x/full

Presynaptic cannabinoid CB1 receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575049/?tool=pmcentrez

Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice. (full - 2004)

http://molpharm.aspetjournals.org/content/66/2/204.long

CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity (full - 2004) http://www.nature.com/ijo/journal/v28/n4/full/0802583a.html

Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors. (abst – 2004) http://www.ncbi.nlm.nih.gov/pubmed/14667455

Tourette syndrome is not caused by mutations in the central cannabinoid receptor (CNR1) gene. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15108190
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 191 - 195

Cb(1) Receptor Mediation of Cannabinoid Behavioral Effects in Male and Female Rats. (abst - 2004) http://medical-journals.healia.com/doc/14991224/CB1-receptor-mediation-of-cannabinoid-behavioral- effects-in-male-and-female-rats

Context-dependent effects of CB1 cannabinoid gene disruption on anxiety-like and social behaviour in mice (abst – 2004)
http://onlinelibrary.wiley.com/doi/10.1111/j.1460- 9568.2004.03293.x/abstract;jsessionid=15C92BB3498FAF0EE40394675E8B1800.d01t01

Overeating, Alcohol and Sucrose Consumption Decrease in Cb1 Receptor Deleted Mice. (abst – 2004) http://medical-journals.healia.com/doc/12770700/Overeating-alcohol-and-sucrose-consumption-decrease- in-CB1-receptor-deleted-mice

Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html

Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1) (full - 2005) http://www.nature.com/tpj/journal/v5/n2/full/6500301a.html

Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300535a.html

Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087161/?tool=pmcentrez

The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis. (full - 2005) http://www.jstage.jst.go.jp/article/tjem/207/2/207_99/_article

Direct cerebrovascular effects of CB1 receptor activation by the synthetic endocannabinoid HU-210 in vivo (full - 2005) http://www.nature.com/jcbfm/journal/v25/n1s/full/9591524.0581a.html

CB1 cannabinoid receptor-mediated modulation of food intake in mice (full - 2005)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576140/?tool=pmcentrez

Evidence that the plant cannabinoid Δ9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751228/?tool=pubmed

Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptors. (full – 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266095/?tool=pubmed
191

Antidepressant-like Activity and Modulation of Brain Monoaminergic Transmission by Blockade of Anandamide Hydrolysis. (full – 2005) http://www.pnas.org/content/102/51/18620.long

Ethanol Induces Higher Bec in Cb1 Cannabinoid Receptor Knockout Mice While Decreasing Ethanol Preference. (full – 2005) http://alcalc.oxfordjournals.org/content/40/1/54.long

The Endogenous Cannabinoid System. Therapeutic Implications for Neurologic and Psychiatric Disorders (abst – 2005) http://medical-journals.healia.com/doc/15776259/The-endogenous-cannabinoid-system.-Therapeutic- implications-for-neurologic-and-psychiatric-disorders

The endocannabinoid system drives neural progenitor proliferation. (full – 2005)

http://www.fasebj.org/content/early/2005/09/30/fj.05-3995fje.long

Analgesia through endogenous cannabinoids (full - 2005)

http://www.cmaj.ca/cgi/content/full/173/4/357?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=end ocannabinoid&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=date&resourcetype=HW CIT

Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/15953683

Finding of endocannabinoids in human eye tissues: implications for glaucoma. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/15823551

Marijuana May Grow Neurons in the Brain (news - 2005)

http://www.medpagetoday.com/Psychiatry/AnxietyStress/1934

The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769341/?tool=pmcentrez

AM 251 produces sustained reductions in food intake and body weight that are resistant to tolerance and conditioned taste aversion (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615836/?tool=pmcentrez

Activation of the Cannabinoid Type-1 Receptor Mediates the Anticonvulsant Properties

of Cannabinoids in the Hippocampal Neuronal Culture Models of Acquired Epilepsy and

Status Epilepticus (full - 2006)

http://jpet.aspetjournals.org/content/317/3/1072.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT#ref-list-1

Activation of G-proteins in brain by endogenous and exogenous cannabinoids. (full – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16584117

The Cannabinoid Cb1 Receptor Antagonist Rimonabant Attenuates the Hypotensive

Effect of Smoked Marijuana in Male Smokers. (full – 2006)

http://www.ahjonline.com/article/S0002-8703(05)01013-6/fulltext
192

Cannabinoid (CB1) Receptor Activation Inhibits Trigeminovascular Neurons
(full - 2006) http://jpet.aspetjournals.org/content/320/1/64.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=c annabis&searchid=1&FIRSTINDEX=3680&resourcetype=HWCIT

Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808496/?tool=pmcentrez

Antinociceptive effect of cannabinoid agonist WIN 55,212–2 in rats with a spinal cord injury (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez

Involvement of Neuronal Cannabinoid Receptor CB1 in Regulation of Bone Mass and Bone Remodeling (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238031/?tool=pmcentrez

Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis (full - 2006)

http://www.fasebj.org/cgi/reprint/02- 1129fjev1?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cannabinoid&andorexactfulltext=and&s earchid=1&FIRSTINDEX=10&sortspec=relevance&resourcetype=HWCIT

Cannabinoid CB1 Receptor Mediates Fear Extinction via Habituation-Like Processes (full - 2006) http://www.jneurosci.org/cgi/content/full/26/25/6677?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT

Evolutionary Origins of the Endocannabinoid System. (abst – 2006)

http://medical-journals.healia.com/doc/16434153/Evolutionary-origins-of-the-endocannabinoid-system

Science: Cannabinoids reduce inflammation of the bowel in animal model (news - 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=216#1

PET imaging of cerebral cannabinoid CB1 receptors with [11C]JHU75528 (news – 2006) http://www.news-medical.net/news/2006/06/06/18312.aspx

The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling. (full - 2007) http://www.fasebj.org/cgi/content/full/22/1/285

Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner (full – 2007) http://www.jbc.org/content/283/10/6005.full?sid=931583b1-e797-43e0-8296-7fd75bb49403#sec-4

CANNABINOID-INDUCED HYPERPHAGIA: CORRELATION WITH INHIBITION

OF PROOPIOMELANOCORTIN NEURONS? (full - 2007)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720321/?tool=pmcentrez
193

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234438/

The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis (full - 2007) http://www.jbc.org/content/282/33/23892.full

Expression of Cannabinoid CB1 Receptors in Models of Diabetic Neuropathy
(full - 2007) http://jpet.aspetjournals.org/content/323/2/508.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT

Cannabinoid CB1 and CB2 Receptors and Fatty Acid Amide Hydrolase Are Specific Markers of Subtypes in Human Multiple Sclerosis (full - 2007) http://www.jneurosci.org/cgi/content/full/27/9/2396?maxtoshow=&hits=10&RESULTFORMAT=&fulltext =cannabinoid&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype =HWCIT

Cannabinoid action in the olfactory epithelium (full - 2007)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1815290/?tool=pmcentrez

Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB1 and TRPV1 receptors (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128772/?tool=pmcentrez

Control of spasticity in a multiple sclerosis model is mediated by CB1, not CB2, cannabinoid receptors. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189718/?tool=pubmed

Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190006/?tool=pmcentrez

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro (full - 2007) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2189767&tool=pmcentrez

Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner (full – 2007) http://www.jbc.org/content/283/10/6005.full

The endocannabinoid system and neurogenesis in health and disease. (abst - 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17404371

The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17583570

Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance (abst - 2007) http://medical-journals.healia.com/doc/17320118/Repeated-treatment-with-cannabidiol-but-not-Delta9- tetrahydrocannabinol-has-a-neuroprotective-effect-without-the-development-of-tolerance
194

Cannabinoid CB1 receptors in the paraventricular nucleus and central control of penile erection: immunocytochemistry, autoradiography and behavioral studies (abst – 2007) http://pharmgkb.org/pmid/17507169

Whole-Body Biodistribution and Radiation Dosimetry of the Human Cannabinoid Type- 1 Receptor Ligand ^sup 18^F-MK-9470 in Healthy Subjects (full - 2008) http://findarticles.com/p/articles/mi_hb5979/is_200803/ai_n32266209/

Genetic Variations at the Endocannabinoid Type 1 Receptor Gene (CNR1) Are Associated with Obesity Phenotypes in Men (full - 2008) http://jcem.endojournals.org/cgi/content/full/92/6/2382

Cannabinoid Receptor 1 Gene Association With Nicotine Dependence (full - 2008)

http://archpsyc.ama- assn.org/cgi/content/full/65/7/816?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&se archid=1&FIRSTINDEX=0&resourcetype=HWCIT

Association of the Cannabinoid Receptor Gene (CNR1) With ADHD and Post-Traumatic Stress Disorder (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685476/?tool=pubmed

The cannabinoid CB1 receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577903/?tool=pmcentrez

Cannabinoid Modulation of Cutaneous A{delta} Nociceptors During Inflammation (full - 2008) http://jn.physiology.org/cgi/reprint/100/5/2794

Topical WIN55212-2 Alleviates Intraocular Hypertension in Rats Through a CB1 Receptor-Mediated Mechanism of Action (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637200/?tool=pmcentrez

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9- tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/

Loss of Cannabinoid Receptor CB1 Induces Preterm Birth (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553193/?tool=pmcentrez

Endocannabinoids and cannabinoid receptors in ischaemia–reperfusion injury and preconditioning (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219536/?tool=pmcentrez

Pharmacological Inhibition of CB1 Cannabinoid Receptor Protects Against Doxorubicin- Induced Cardiotoxicity (full - 2008) http://content.onlinejacc.org/cgi/content/full/50/6/528

Cannabinoid receptors and the regulation of bone mass (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219540/?tool=pmcentrez
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momofthegoons

Vapor Accessory Addict
Staff member
Pages 196 - 200

Loss of cannabinoid receptor 1 accelerates intestinal tumor growth (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561258/?tool=pubmed

Cannabinoid CB1 Receptors Are Expressed by Parietal Cells of the Human Gastric Mucosa (full – 2008) http://jhc.sagepub.com/content/56/5/511.full

Feeding induced by cannabinoids is mediated independently of the melanocortin system. (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386290/?tool=pubmed

Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776723/?tool=pubmed

Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18279310

Dysregulation of the endocannabinoid system in obesity. (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18426509

High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18615640

Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth (news - 2008) http://www.sciencedaily.com/releases/2008/08/080801074056.htm

Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer (news – 2008) http://www.news-medical.net/news/2008/08/03/40485.aspx

Actions of delta-9-tetrahydrocannabinol in cannabis (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731700/?tool=pmcentrez

Cannabinoid Receptor 1 Binding Activity and Quantitative Analysis of Cannabis sativa L. Smoke and Vapor (full – 2009) http://www.jstage.jst.go.jp/article/cpb/58/2/201/_pdf

Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660732/?tool=pmcentrez

Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688760/?tool=pubmed

The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human Kaposi‘s sarcoma cells in vitro (full - 2009) http://science.iowamedicalmarijuana.org/pdfs/cancer/Luca et al 2009 19539619.pdf
196

Cannabinoid-1 (CB1) receptors regulate colonic propulsion by acting at motor neurons within the ascending motor pathways in mouse colon (full - 2009) http://ajpgi.physiology.org/cgi/content/full/296/1/G119?maxtoshow=&hits=80&RESULTFORMAT=&full text=cannabinoid&searchid=1&FIRSTINDEX=160&resourcetype=HWCIT

Characterization of the Endocannabinoid System in Human Neuronal Cells and Proteomic Analysis of Anandamide-induced Apoptosis (full – 2009) http://www.jbc.org/content/284/43/29413.full

Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma (full - 2009) http://mct.aacrjournals.org/content/8/7/1838.full

Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity. (full – 2009) http://brain.oxfordjournals.org/content/132/11/3152.long

Effects of the cannabinoid CB1 receptor antagonist AM 251 on the reinstatement of nicotine-conditioned place preference by drug priming in rats. (full - 2009) http://www.if-pan.krakow.pl/pjp/pdf/2009/2_304.pdf

Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19897083

Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. (abst – 2009) http://www.sciencedirect.com/science/article/pii/S0006899308030588

Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications (abst – 2009) http://pharmgkb.org/pmid/19897083

Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19524019

Endogenous cannabinoid signalling and energy balance (abst – 2009)

http://gradworks.umi.com/NR/44/NR44386.html

The cannabinoid system: cannabinoids and receptors (news – 2009)

http://www.examiner.com/health-science-in-vancouver/the-cannabinoid-system-cannabinoids-and- receptors

Understanding Functional Residues of the Cannabinoid CB1 for Drug Discovery. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980537/?tool=pubmed

Cannabinoid receptor 1 binding activity and quantitative analysis of Cannabis sativa L. smoke and vapor. (full - 2010) http://www.jstage.jst.go.jp/article/cpb/58/2/58_201/_article
197

The Cannabinoid 1 Receptor (CNR1) 1359 G/A Polymorphism Modulates Susceptibility to Ulcerative Colitis and the Phenotype in Crohn's Disease (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829088/?tool=pmcentrez

Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype (full – 2010) http://ajpgi.physiology.org/content/299/1/G63.full?sid=fc6948f0-78cf-405c-981b-afaa05ee417c

Cannabinoid–Dopamine Interaction in the Pathophysiology and Treatment of CNS Disorders (full – 2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5949.2010.00144.x/full

Voluntary Exercise and Sucrose Consumption Enhance Cannabinoid CB1 Receptor Sensitivity in the Striatum (full - 2010) http://www.nature.com/npp/journal/v35/n2/full/npp2009141a.html

Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898685/?tool=pubmed

AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006205/?tool=pubmed

Widespread Decrease of Type 1 Cannabinoid Receptor Availability in Huntington Disease In Vivo (full – 2010) http://jnm.snmjournals.org/cgi/content/full/51/9/1413

JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB(1) receptor agonist. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931559/?tool=pubmed

Attenuation of morphine antinociceptive tolerance by a CB(1) receptor agonist and an NMDA receptor antagonist: Interactive effects. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813317/?tool=pubmed

Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed

Genes differentially expressed in CB1 knockout mice: involvement in the depressive-like phenotype. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20692131

Pharmacological exploitation of the endocannabinoid system: new perspectives for the treatment of depression and anxiety disorders? (abst – 2010) http://www.unboundmedicine.com/medline/ebm/record/20512266/abstract/[Pharmacological_exploitat ion_of_the_endocannabinoid_system:_new_perspectives_for_the_treatment_of_depression_and_anxiety_d isorders%5D_
198

Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation (abst - 2010) http://www.nature.com/npp/journal/vaop/ncurrent/full/npp2010214a.html

Expression of cannabinoid receptors in human kidney. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20607655

Abnormal sensitivity of cannabinoid CB1 receptors in the striatum of mice with experimental amyotrophic lateral sclerosis. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/19452308

Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20097273

Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus. (abst – 2010) http://www.unboundmedicine.com/medline/ebm/record/20417220/abstract/Delta9_tetrahydrocannabinol_is _a_full_agonist_at_CB1_receptors_on_GABA_neuron_axon_terminals_in_the_hippocampus_

Regulation of nausea and vomiting by cannabinoids (abst - 2010)

http://onlinelibrary.wiley.com/doi/10.1111/j.1476- 5381.2010.01176.x/abstract;jsessionid=56CED9CE51B025C161AA2E821BEC94ED.d01t01

A common variation in the cannabinoid 1 receptor (CNR1) gene is associated with pre- eclampsia in the Central European population. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21129839

Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/19931541

Expression of cannabinoid receptor I during mice skin incised wound healing course (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20967946

Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20618415

Study shows direct cellular interaction between endocannabinoids and alcohol in the brain (news - 2010) http://www.news-medical.net/news/20100513/Study-shows-direct-cellular-interaction-between- endocannabinoids-and-alcohol-in-the-brain.aspx

Cannabidiol (CBD) as an Anti-Arrhythmic – the Role of the CB1 Receptors
(news – 2010) http://cannabisclinicians.org/2011/cannabidiol-cbd-as-an-anti-arrhythmic-the-role-of-the-cb1-receptors/
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Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis (full - 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025486/?tool=pubmed

Increased Expression of Cannabinoid CB(1) Receptors in Achilles Tendinosis. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169627/?tool=pubmed

WIN55,212-2 induces cytoplasmic vacuolation in apoptosis-resistant MCL cells. (full – 2011) http://www.nature.com/cddis/journal/v2/n11/full/cddis2011106a.html

Local activation of cannabinoid CB1 receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents. (full – 2011) http://www.molecularpain.com/content/pdf/1744-8069-7-31.pdf

Cannabinoid CB1 receptor antagonists modulate transport activity of multidrug resistance-associated proteins MRP1, MRP2, MRP3, and MRP4 (full – 2011) http://dmd.aspetjournals.org/content/early/2011/04/21/dmd.110.037812.full.pdf+html?maxtoshow=&hits=8 0&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcet ype=HWCIT

Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB1 receptors. (full – 2011)
http://www.jneuroinflammation.com/content/pdf/1742-2094-8-102.pdf

Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging (full– 2011)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131310/?tool=pubmed

Endocannabinoid system in cardiovascular disorders - new pharmacotherapeutic opportunities (full – 2011)

http://www.jpbsonline.org/article.asp?issn=0975- 7406;year=2011;volume=3;issue=3;spage=350;epage=360;aulast=Cunha

Variation in the human Cannabinoid Receptor (CNR1) gene modulates gaze duration for happy faces. (full – 2011) http://www.molecularautism.com/content/pdf/2040-2392-2-10.pdf

Deficiency of Dietary Omega-3 May Explain Depressive Behaviors
(summary- 2011) http://www.thefreelibrary.com/Deficiency+of+Dietary+Omega-3+May+Explain+Depressive+Behaviors.- a0248155576

Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21873455

Possible involvement of the endocannabinoid system in memory modulation effect of general anesthetics (abst - 2011) http://www.unboundmedicine.com/medline/ebm/record/21555187/abstract/Possible_involvement_of_the_e ndocannabinoid_system_in_memory_modulation_effect_of_general_anesthetics_
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