Meds Cannabinoids

[momofthegoons]

More THC doesn’t mean you get higher, study says​

High-THC cannabis concentrates boost levels of THC in the blood more than smoking cannabis flower, but they don’t necessarily produce a stronger “high,” a new study says.

The use of concentrates produced significantly higher levels of THC in blood plasma, the study found, yet participants who consumed cannabis flower and those who consumed cannabis concentrates “showed similar neurobehavioral patterns after acute cannabis use.” A range of short-term measures of impairment did not change with the strength of the cannabis consumed.

The researchers surmise that may be because concentrate users have greater tolerance to the effects of THC, or that “cannabinoid receptors may become saturated with THC” when consumed at higher levels.

The study, published in JAMA Psychiatry, surveyed 121 users of cannabis flower and concentrate who were randomly instructed to purchase and consume higher and lower THC products.

The study included 55 flower users and 66 concentrate users between 21 and 70, who had used cannabis four times in the past month, did not use tobacco on a daily basis, and had prior use of concentrates with no adverse reaction, among other criteria.

Buy 3 grams and come back in 5 days​

The flower test subjects were instructed to purchase 3 grams of either a 16% THC strain or a 24% THC strain, while the concentrate participants were randomized to purchase 1 gram of either 70% or 90% THC concentrate.

Federal regulations in the United States prohibit researchers from providing any cannabis to research subjects that isn’t produced by a single farm at the University of Mississippi, which many researchers have criticized as being “junk, ill-suited for clinical trials,” with levels of THC far below that which is readily available in the legal — and illegal — cannabis market. Some researchers have chosen to sidestep that rule by instructing participants to purchase their own cannabis from legal dispensaries.

Between the baseline assessment and the experimental session, the participants were given a five-day period to “familiarize themselves with their study cannabis.” On the day of the experiment, the participants used the cannabis at their home with their preferred method of use, and then were assessed in a mobile laboratory dispatched to check their short-term intoxication.

The relationship between potency and impairment​

The study looked to answer three main questions: how short term use of cannabis flower and concentrate is associated with THC plasma levels, subjective intoxication and mood, cognitive performance and balance, if these associations differ between flower and concentrate users, and if these associations differ in relation to THC potency.

Cannabis intoxication was measured using the 12-item Addiction Research Center Inventory-marijuana effects scale, as well as according to a three-item cannabis intoxication scale that rated three sensations: mentally stoned, physically stoned, and feeling high. They were also asked to complete four cognitive tasks, including three separate memory related tasks and a “quiet standing balance” test.

The concentrate users “reported more frequent current concentrate use and exhibited greater blood levels of THC and metabolites at baseline.” Nonetheless, “despite this higher THC exposure, concentrate users did not show greater short-term subjective, cognitive, or balance impairment,” according to the researchers.

The researchers in the current study said that part of their motivation was to assess the potential negative effects of THC on the brain, and that “the existing literature is limited by the use of low-THC products and drug administration approaches that do not reflect legal market cannabis use.”

They also said that the “much higher” THC exposure in concentrate users is reason for concern about the “long-term clinical and neurohabavioral implications of concentrate use.”

 

[momofthegoons]

There are reviews and links to a Delta 11 product in this article. I have left one of the links, but we are not promoting this product in any way here at the Asylum.​

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What Is Delta 11 THC?​

With the rise of technology and research, it’s safe to say the cannabis industry is evolving. Companies are pushing out products featuring new cannabinoids like Delta 8 THC, Delta 10 THC, and, you guessed it, Delta 11 THC.

Although we’ve come to know the effects and experience with Delta 8 and Delta 10, Delta 11 is the newest contender that consumers need to learn more about.

As we continue discussing new cannabinoids, it doesn’t take long for cannabinoid-centric companies to release products featuring these compounds to further diversify your cannabis experiences, like Binoid’s Delta 11 THC / 11 HXY 2-Gram Disposable Vape.

This powerhouse vape is the first real Delta 11 THC / 11 HXY THC Disposable on the market, boasting two grams of these rare cannabinoids and premium terpenes in one heady and flavorful blend.

Before we dive deeper into this cutting-edge vaporizer, let’s give you a rundown on what Delta 11 THC is, how it differs from other cannabinoids, and what to expect from its effects.

What Is Delta 11 THC?​

Delta 11 THC is a cannabinoid that’s found naturally in the hemp plant but in very small traces. New technology has allowed companies to isolate this cannabinoid and explore it to examine its effects and potential benefits.
It’s a psychoactive cannabinoid, just like Delta 8, Delta 9, and Delta 10. However, Delta 11 THC has shown promise to be roughly 3x stronger than Delta 9 THC. It’s a powerful compound that mustn’t be dosed irresponsibly. If you’re up to the task, read on for more information on where to get your hands on some new, potent Delta 11 THC.

What Does Delta 11 THC Feel Like?​

As mentioned, the effects of Delta 11 THC are nearly 3x stronger than Delta 9 THC, the primary psychoactive cannabinoid. That statement alone is pretty intriguing.
Besides its strong potency, anecdotal reports about Delta 11 state that it offers an unmatched euphoria compared to other Deltas. In short, expect positive effects like:

• Relaxation
• Powerful cerebral and body experiences
• Elevated mood
• Anxiety and stress-relief
• Heightened euphoria

The adverse effects of Delta 11 aren’t proven, but what’s noted is nothing far from your typical adverse effects of smoking weed, like:

• Dry mouth
• Lethargy
• Headache (after excessive use)

Where To Find Trusted Delta 11 THC​

Binoid’s Delta 11 THC / 11 HXY 2-Gram Disposable Vape is the first of its kind, the debut Delta 11 and 11 HXY disposable vape on the market. It comes from a brand well-known as the #1 source for the newest cannabinoids, backed by rigorous lab testing for quality, purity, and potency.

Needless to say, the Delta 11 THC / 11 HXY 2-Gram Disposable Vape is out of this world. It comes in two delicious flavors, aptly named This Slapz (Hybrid) and Cherry Bonkers (Hybrid). Whatever your palate desires, this premium vaporizer will satisfy your canna cravings.

Before we continue, you might be wondering what 11 HXY is. Short for 11-Hydroxy-THC, this compound is not Delta 11 THC but is entirely its own entity with effects similar to Delta 9 THC. Because of its popular and fan-favorite effects, Binoid combined it with Delta 11 THC and premium terpenes in a convenient disposable for an extraordinary cannabis experience.

Not to mention its whopping 2-gram quantity, meaning you can elongate your sessions without worrying about running out of precious distillate too quickly.

Finally, we must warn you that Binoid’s Delta 11 THC / 11 HXY 2-Gram Disposable Vape is incredibly potent and must be used responsibly. Take a hit, wait half an hour, and see how the magical world of Delta 11 and 11 HXY treats you.

 

[momofthegoons]

Delta 11 THC​

Delta 11 THC is a very minor, naturally occurring cannabinoid in the hemp plant, rather than a synthesized one. While it’s considered new to us, it was in fact referenced for the first time in the 1970s, although practically no research exists that gives us meaningful information about it. Besides the fact that we know it’s psychoactive, we barely have any research to reference to get a clearer picture of its properties.

What we do know is that delta 11 THC can be made through a process of isomerization, just like all cannabinoids, because of the fact that its molecular makeup matches all other cannabinoids in hemp, including cannabidiol (CBD). This comes from the knowledge that every cannabinoid is ultimately derived from cannabigerol (CBG), the “mother cannabinoid” that eventually splits off into 100+ individual cannabinoids once the hemp plant matures.

It's important to make one distinction, as delta 11 THC is commonly confused with 11-hydroxy THC. The latter is a metabolite that THC converts into once it reaches the liver, to get broken down and become THC-COOH, the metabolite notorious for causing a positive drug test result. Delta 11 THC is not 11-hydroxy THC, but you may come across some confusion while researching the cannabinoid.