Whisper
Well-Known Member
This company also sells CBD. We are not endorsing the company or their products. However, there does seem to be a wealth of useful information that they've collected.
CBD FOR ACNE
CBD FOR ADDICTION & ALCOHOLISM
CBD FOR ALS
CBD FOR ALZHEIMER’S
CBD FOR ANOREXIA
CBD FOR ANTIBIOTIC RESISTANCE
CBD FOR ANXIETY
CBD FOR ARTHRITIS
CBD FOR ASTHMA
CBD FOR ATHEROSCLEROSIS
CBD FOR AUTISM
CBD FOR AUTOIMMUNE DISEASE
CBD FOR BIPOLAR
CBD FOR CANCER
CBD FOR BLADDER CANCER
CBD FOR BRAIN CANCER
CBD FOR BREAST CANCER
CBD FOR COLON CANCER
CBD FOR ENDOCRINE CANCER
CBD FOR KAPOSI SARCOMA
CBD FOR LEUKEMIA
CBD FOR LUNG CANCER
CBD FOR PROSTATE CANCER
CBD FOR SKIN CANCER
CBD FOR COLITIS AND CROHN’S
CBD FOR DEPRESSION
CBD FOR DIABETES
CBD FOR EPILEPSY AND SEIZURES
CBD FOR GLAUCOMA
CBD FOR HEART DISEASE
CBD FOR HIV AND AIDS
CBD FOR HUNTINGTON’S DISEASE
CBD FOR INFLAMMATION
CBD FOR IRRITABLE BOWEL SYNDROME
CBD FOR KIDNEY DISEASE
CBD FOR LIVER DISEASE
CBD FOR MIGRAINES
CBD FOR MOOD DISORDERS
CBD FOR MOTION SICKNESS
CBD FOR MULTIPLE SCLEROSIS
CBD FOR NEURODEGENERATION
CBD FOR OBESITY
CBD FOR OBSESSIVE COMPULSIVE DISORDER
CBD FOR OSTEOPOROSIS/ BONE HEALTH
CBD FOR PAIN
CBD FOR PARKINSON’S DISEASE
CBD FOR PRION DISEASE (MAD COW)
CBD FOR PTSD (POST TRAUMATIC STRESS DISORDER)
CBD FOR RHEUMATISM
CBD FOR SCHIZOPHRENIA
CBD FOR SCLERODERMA
CBD FOR SICKLE CELL ANEMIA
CBD FOR SKIN CONDITIONS
CBD FOR SLEEP DISORDERS
CBD FOR SPINAL CORD INJURY
CBD FOR STRESS
CBD FOR STROKE
CBD FOR TRAUMATIC BRAIN INJURY (TBI)
CBD FOR WEIGHT LOSS
CBD FOR ACNE
- The safety and efficacy of 3% Cannabis seeds extract cream for reduction of human cheek skin sebum and erythema content.
- Cannabidiol as a Treatment for Acne?
- Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes.
- The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities.
- Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling.
- Endocannabinoid signaling and epidermal differentiation.
- Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment.
- Searching for a neurobiological basis for self-medication theory in ADHD comorbid with substance use disorders: an in vivo study of dopamine transporters using (99m)Tc-TRODAT-1 SPECT.
- Cannabidiol and clozapine reverse MK-801-induced deficits in social interaction and hyperactivity in Sprague-Dawley rats.
- Subtypes of attention deficit-hyperactivity disorder (ADHD) and cannabis use.
- Childhood and current ADHD symptom dimensions are associated with more severe cannabis outcomes in college students.
- “I Use Weed for My ADHD”: A Qualitative Analysis of Online Forum Discussions on Cannabis Use and ADHD.
CBD FOR ADDICTION & ALCOHOLISM
- Cannabidiol as an Intervention for Addictive Behaviors: A Systematic Review of the Evidence
- Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings.
- Inhibition of monoacylglycerol lipase reduces nicotine withdrawal.
- Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1A receptors in the dorsal raphe nucleus.
- Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances.
- Differential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats.
- Impact of cannabis use during stabilization on methadone maintenance treatment.
- Medical cannabis laws and opioid analgesic overdose mortality in the United States, 1999-2010.
- Dysregulation of cannabinoid CB1 receptor and associated signaling networks in brains of cocaine addicts and cocaine-treated rodents.
- Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity.
- Transdermal delivery of cannabidiol attenuates binge alcohol-induced neurodegeneration in a rodent model of an alcohol use disorder
- Cannabidiol Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway through a Novel mTOR/p70S6 Kinase Signaling Pathway.
- Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders.
- Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage.
- Epigenetic mechanisms associated with addiction-related behavioural effects of nicotine and/or cocaine: implication of the endocannabinoid system.
- Cannabidiol Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway through a Novel mTOR/p70S6 Kinase Signaling Pathway.
CBD FOR ALS
- Cannabis and amyotrophic lateral sclerosis: hypothetical and practical applications, and a call for clinical trials.
- [Self-medication with cannabidiol oil in a patient with primary lateral sclerosis].
- Neurological Aspects of Medical Use of Cannabidiol.
CBD FOR ALZHEIMER’S
- Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease.
- The therapeutic potential of the endocannabinoid system for Alzheimer’s disease.
- Endocannabinoid signalling in Alzheimer’s disease.
- A Molecular Link Between the Active Component of Marijuana and Alzheimer’s Disease Pathology
- Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells.
- The role of endocannabinoid signaling in the molecular mechanisms of neurodegeneration in Alzheimer’s disease.
- Cannabinoids for the treatment of dementia.
- Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression.
- Cannabidiol: a promising drug for neurodegenerative disorders?
- Cannabinoid receptor 1 deficiency in a mouse model of Alzheimer’s disease leads to enhanced cognitive impairment despite of a reduction in amyloid deposition
- The role of the endocannabinoid system in Alzheimer’s disease: facts and hypotheses.
- The role of phytochemicals in the treatment and prevention of dementia.
- Cannabinoids for the treatment of dementia.
- Cannabidiol promotes amyloid precursor protein ubiquitination and reduction of beta amyloid expression in SHSY5YAPP+ cells through PPARγ involvement.
- Cannabinoids for treatment of Alzheimer’s disease: moving toward the clinic.
- Can Marijuana Prevent Alzheimer’s?
- Safety and Efficacy of Medical Cannabis Oil for Behavioral and Psychological Symptoms of Dementia: An-Open Label, Add-On, Pilot Study.
- Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease.
- Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview.
- Delineating the Efficacy of a Cannabis-Based Medicine at Advanced Stages of Dementia in a Murine Model.
- Cannabidiol Modulates the Expression of Alzheimer’s Disease-Related Genes in Mesenchymal Stem Cells
- In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer’s Disease.
- Neurological Aspects of Medical Use of Cannabidiol.
CBD FOR ANOREXIA
- Leptin, ghrelin, and endocannabinoids: potential therapeutic targets in anorexia nervosa.
- The role of the endocannabinoid system in eating disorders: neurochemical and behavioural preclinical evidence.
- Cancer cachexia and cannabinoids.
CBD FOR ANTIBIOTIC RESISTANCE
- Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.
- Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol.
CBD FOR ANXIETY
- Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug.
- Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa.
- Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients.
- Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report.
- Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation.
- Effects of cannabidiol (CBD) on regional cerebral blood flow.
- The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors.
- The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system.
- Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
- A Systematic Review of Plant-Derived Natural Compounds for Anxiety Disorders.
- The Endocannabinoid System and Anxiety.
- Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders.
- Effect of prior foot shock stress and Δ9-tetrahydrocannabinol, cannabidiolic acid, and cannabidiol on anxiety-like responding in the light-dark emergence test in rats.
- Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report.
- Cannabidiol Does Not Dampen Responses to Emotional Stimuli in Healthy Adults.
CBD FOR ARTHRITIS
- Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis.
- The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.
- Involvement of the endocannabinoid system in osteoarthritis pain.
- The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55.
- Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis.
CBD FOR ASTHMA
- The role of cannabinoids in inflammatory modulation of allergic respiratory disorders, inflammatory pain and ischemic stroke.
- Allergen challenge increases anandamide in bronchoalveolar fluid of patients with allergic asthma.
- Activation of cannabinoid receptors prevents antigen-induced asthma-like reaction in guinea pigs.
- Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways.
- Evaluation of Serum Cytokines Levels and the Role of Cannabidiol Treatment in Animal Model of Asthma
CBD FOR ATHEROSCLEROSIS
- The role of the endocannabinoid system in atherosclerosis.
- Cannabinoid receptors in atherosclerosis.
- [The potential use of cannabidiol in the therapy of metabolic syndrome].
CBD FOR AUTISM
- Endocannabinoid Signaling in Autism
- Mutations found in individuals with autism interfere with endocannabinoid signaling in the brain
- Cannabinoid receptor type 2, but not type 1, is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders.
- A Novel Approach to the Symptomatic Treatment of Autism
- Consequences of cannabinoid and monoaminergic system disruption in a mouse model of autism spectrum disorders.
- Targeting the endocannabinoid system in the treatment of fragile X syndrome.
- Deficient adolescent social behavior following early-life inflammation is ameliorated by augmentation of anandamide signaling.
CBD FOR AUTOIMMUNE DISEASE
CBD FOR BIPOLAR
CBD FOR CANCER
- Cannabidiol as potential anticancer drug.
- Cannabidiol inhibits angiogenesis by multiple mechanisms.
- Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1.
- In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma.
- The influence of biomechanical properties and cannabinoids on tumor invasion.
- Antitumorigenic targets of cannabinoids – current status and implications.
- Cannabinoids – a new weapon against cancer?
- Cannabidiol, a novel inverse agonist for GPR12.
CBD FOR BLADDER CANCER
CBD FOR BRAIN CANCER
- Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival.
- Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines.
- Systematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas.
- Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism.
- Id-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target.
- Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents.
- Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect.
- Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme.
- Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture.
CBD FOR BREAST CANCER
- Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.
- Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy.
- Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis.
- Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells.
- Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration.
- Cannabidiolic acid-mediated selective down-regulation of c-fos in highly aggressive breast cancer MDA-MB-231 cells: possible involvement of its down-regulation in the abrogation of aggressiveness.
CBD FOR COLON CANCER
- Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer.
- Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.
CBD FOR ENDOCRINE CANCER
- Endocannabinoids in endocrine and related tumours.
- A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells.
CBD FOR KAPOSI SARCOMA
CBD FOR LEUKEMIA
- Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression.
- Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression.
- Cannabidiol Reduces Leukemic Cell Size – But Is It Important?
CBD FOR LUNG CANCER
- Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.
- COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells.
- Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells.
CBD FOR PROSTATE CANCER
- Towards the use of non-psychoactive cannabinoids for prostate cancer.
- In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines
- Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.
CBD FOR SKIN CANCER
CBD FOR COLITIS AND CROHN’S
- Cannabidiol in inflammatory bowel diseases: a brief overview.
- Cannabis finds its way into treatment of Crohn’s disease.
- Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.
- Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis.
- The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis.
- Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice.
- Cannabinoids and the gut: new developments and emerging concepts.
- Endocannabinoids and the gastrointestinal tract.
- Cannabinoids and gastrointestinal motility: animal and human studies.
- Manipulation of the Endocannabinoid System in Colitis: A Comprehensive Review.
- Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn’s Disease, a Randomized Controlled Trial.
CBD FOR DEPRESSION
- Endocannabinoid system dysfunction in mood and related disorders.
- Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa.
- The endocannabinoid system and the treatment of mood and anxiety disorders.
- Endocannabinoid signaling in the etiology and treatment of major depressive illness.
- Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors.
- Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants.
- Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.
- Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress.
- Serum contents of endocannabinoids are correlated with blood pressure in depressed women.
- The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants.
- Antidepressants and changes in concentration of endocannabinoids and N-acylethanolamines in rat brain structures.
- Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors.
- Prohedonic Effect of Cannabidiol in a Rat Model of Depression.
- Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa.
CBD FOR DIABETES
- The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults
- Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.
- Cannabidiol lowers incidence of diabetes in non-obese diabetic mice.
- Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes.
- Cannabidiol arrests onset of autoimmune diabetes in NOD mice.
- Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation.
- Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes.
- The endocannabinoid system in obesity and type 2 diabetes.
- Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes.
- The endocannabinoid system and plant-derived cannabinoids in diabetes and diabetic complications.
- Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain.
- Biochemical and immunohistochemical changes in delta-9-tetrahydrocannabinol-treated type 2 diabetic rats.
- Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study.
- Endocannabinoid system participates in neuroendocrine control of homeostasis.
- The emerging role of the endocannabinoid system in endocrine regulation and energy balance.
- Endocannabinoids in endocrine and related tumours.
- Role of the endocannabinoid system in food intake, energy homeostasis and regulation of the endocrine pancreas.
- The role of the endocannabinoid system in the neuroendocrine regulation of energy balance.
CBD FOR EPILEPSY AND SEIZURES
- Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy.
- MEDICINAL MARIJUANA STOPS SEIZURES, BRINGS HOPE TO A LITTLE GIRL
- Cannabis, cannabidiol, and epilepsy–from receptors to clinical response.
- Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), Activate and Desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) Channels in Vitro: Potential for the Treatment of Neuronal Hyperexcitability
- Chronic administration of cannabidiol to healthy volunteers and epileptic patients.
- Endocannabinoid system protects against cryptogenic seizures.
- Seizing an opportunity for the endocannabinoid system.
- Cannabidiol: promise and pitfalls.
- Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
- Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression
- Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures.
- Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo.
- Hypnotic and antiepileptic effects of cannabidiol.
- The cannabinoids as potential antiepileptics.
- Cannabidiol–antiepileptic drug comparisons and interactions in experimentally induced seizures in rats.
- Cannabidiol Post-Treatment Alleviates Rat Epileptic-Related Behaviors and Activates Hippocampal Cell Autophagy Pathway Along with Antioxidant Defense in Chronic Phase of Pilocarpine-Induced Seizure
- Pharmacology of cannabinoids in the treatment of epilepsy.
- Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection.
- Report from a Survey of Parents Regarding the Use of Cannabidiol (Medicinal cannabis) in Mexican Children with Refractory Epilepsy.
- Protective Effects of Cannabidiol against Seizures and Neuronal Death in a Rat Model of Mesial Temporal Lobe Epilepsy.
- Cannabidiol Treatment for Refractory Seizures in Sturge-Weber Syndrome.
- Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy?
- The Consumption of Cannabis by Fibromyalgia Patients in Israel.
- Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
- Cannabis use in patients with fibromyalgia: effect on symptoms relief and health-related quality of life.
- Cannabinoids for fibromyalgia.
CBD FOR GLAUCOMA
- Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite.
- Effect of sublingual application of cannabinoids on intraocular pressure: a pilot study.
CBD FOR HEART DISEASE
- 17 Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors
- Is the cardiovascular system a therapeutic target for CBD?
- Acute administration of CBD in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion
- CBD attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy
- The effect of CBD on ischemia/reperfusion-induced ventricular arrhythmias
- CBD protects against myocardial ischemic reperfusion injury
- Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension
- Cannabidiol protects against doxorubicin-induced cardiomyopathy by modulating mitochondrial function and biogenesis
CBD FOR HIV AND AIDS
CBD FOR HUNTINGTON’S DISEASE
- Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington’s disease
- Cannabinoids: Novel medicines for the treatment of Huntington’s disease
- Sativex-like combination of phytocannabinoids is neuroprotective in malonate-lesioned rats, an inflammatory model of Huntington’s disease: role of CB(1) and CB(2) receptors
- Controlled clinical trial of cannabidiol in Huntington’s disease
- Prospects for cannabinoid therapies in basal ganglia disorders
- Neuroprotective properties of cannabigerol in Huntington’s Disease: Studies in R6/2 mice and 3-nitropropionate-lesioned mice
- Effects of a Sativex-like combination of phytocannabinoids on disease progression in R6/2 mice, an experimental model of Huntington’s Disease
- Neurological aspects of medical use of CBD
CBD FOR INFLAMMATION
- Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
- The endocannabinoid system: an emerging key player in inflammation
- Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice
- Cannabinoids, endocannabinoids, and related analogs in inflammation
- Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: role for the adenosine A(2A) receptor
- Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
- Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis
- Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation
- Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement
- Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
- Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation
- Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death
- Cannabinoids in clinical practice
- Cannabinoids, inflammation, and fibrosis
- Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids
- Endocannabinoid 2-arachidonoylglycerol protects inflammatory insults from sulfur dioxide inhalation via cannabinoid receptors in the brain
- Protective effect of CBD on hydrogen peroxide‑induced apoptosis, inflammation and oxidative stress in nucleus pulposus cells
- Mechanisms of action of CBD in adoptively transferred experimental autoimmune encephalomyelitis
CBD FOR IRRITABLE BOWEL SYNDROME
- Cannabidiol in inflammatory bowel diseases: A brief overview
- CBD reduces intestinal inflammation through the control of neuroimmune axis
- Clinical endocannabinoid deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
- Cannabinoid actions at TRPV channels: Effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation
- Therapeutic potential of cannabinoid-based drugs
- Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease (Biochemical Pharmacology)
- CBD and the gut: New developments and emerging concepts
- Endocannabinoids and the gastrointestinal tract
- CBD and gastrointestinal motility
- Getting into the weed: the role of the endocannabinoid system in the brain-gut axis
- Cannabinoids and GI disorders: Endogenous and exogenous
CBD FOR KIDNEY DISEASE
- Cannabinoids and the kidney: effects in health and disease.
- Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death.
CBD FOR LIVER DISEASE
- The endocannabinoid system and liver diseases
- Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death
- Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis
- Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats
- Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiol
- Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice
- Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation
- Potential of CBD for the treatment of viral hepatitis
CBD FOR MIGRAINES
- Clinical endocannabinoid deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
- Cannabinoids and hallucinogens for headache
- The endocannabinoid system and migraine
- Variations in the cannabinoid receptor 1 gene predispose to migraine
CBD FOR MOOD DISORDERS
- Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders
- The endocannabinoid system and the treatment of mood and anxiety disorders
- The endocannabinoid system and psychiatric disorders
- The endocannabinoid system in the regulation of emotions throughout lifespan: A discussion on therapeutic perspectives
- Endocannabinoid system dysfunction in mood and related disorders
- Effects of CBD on regional cerebral blood flow
- Cannabidiol, neuroprotection and neuropsychiatric disorders
- Therapeutic potential of cannabinoids in psychosis
- Beyond the CB1 receptor: Is cannabidiol the answer for disorders of motivation?
CBD FOR MOTION SICKNESS
- Motion sickness, stress and the endocannabinoid system
- Dexamethasone alleviates motion sickness in rats in part by enhancing the endocannabinoid system
CBD FOR MULTIPLE SCLEROSIS
- Sativex for the management of multiple sclerosis symptoms
- THC & CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis
- Clinical efficacy and effectiveness of Sativex, a combined cannabinoid medicine, in multiple sclerosis-related spasticity
- CBD provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors
- Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis
- Sativex long-term use: An open-label trial in patients with spasticity due to multiple sclerosis
- A double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis
- Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain
- Sativex: Clinical efficacy and tolerability in the treatment of symptoms of multiple sclerosis and neuropathic pain
- Evaluating Sativex in neuropathic pain management
- CBD counteracted the development of experimental MS
- CBD/THC oromucosal spray for multiple sclerosis-related resistant spasticity in daily practice
- Neurological aspects of medical use of CBD
- Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system
- CBD, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus
- Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation
- Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews
- Regulation of nausea and vomiting by cannabinoids
- CBD: its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats
- Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting
- Effect of combined oral doses of THC & CBDA on acute and anticipatory nausea in rat models
CBD FOR NEURODEGENERATION
- Molecular targets of Cannabidiol in neurological disorders
- CBD: A promising drug for neurodegenerative disorders?
- CBD for neurodegenerative disorders: Important new clinical applications for this phytocannabinoid?
- Transdermal delivery of cannabidiol attenuates binge alcohol-induced neurodegeneration in a rodent model of an alcohol use disorder
- Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders
- CBD normalizes caspase 3, synaptophysin, and mitochondrial fission protein DNM1L expression levels in rats with brain iron overload: implications for neuroprotection
- Cannabidiol, neuroprotection and neuropsychiatric disorders
- Short-term effects of CBD after global hypoxia-ischemia in newborn piglets
- CBD reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia
- CBD activates neuronal precursor genes in human gingival mesenchymal stromal cells
- CBD reduces brain damage and improves functional recovery in a neonatal rat model of arterial ischemic stroke
- Interactions between CBD and THC following acute and repeated dosing
- CBD attenuates OGD/R-induced damage by enhancing mitochondrial bioenergetics & modulating glucose metabolism
- Neurological aspects of medical use of CBD
- Modulation of astrocyte activity by cannabidiol, a nonpsychoactive cannabinoid
CBD FOR OBESITY
- Cannabinol and cannabidiol exert opposing effects on rat feeding patterns
- Cannabis and Δ9-tetrahydrocannabinol (THC) for weight loss?
- The endocannabinoid system in obesity and type 2 diabetes
- Role of the endocannabinoid system in abdominal obesity and the implications for cardiovascular risk
- Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
- CBD promotes browning in 3T3-L1 adipocytes
CBD FOR OBSESSIVE COMPULSIVE DISORDER
- Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), D9-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behavi
- Cannabinoid-related agents in the treatment of anxiety disorders: current knowledge and future perspectives
- Current status and prospects for cannabidiol preparations as new therapeutic agents
CBD FOR OSTEOPOROSIS/ BONE HEALTH
- Cannabidiol, a Major Non‐Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts
- Cannabinoid receptors as target for treatment of osteoporosis: A tale of two therapies
- Cannabinoids and bone: Friend or foe?
- Cannabinoid receptor type 1 protects against age-related osteoporosis by regulating osteoblast and adipocyte differentiation in marrow stromal cells
- Cannabinoids and the skeleton: From marijuana to reversal of bone loss
- The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy
- The endovanilloid/endocannabinoid system in human osteoclasts: Possible involvement in bone formation and resorption
- Endocannabinoids and the regulation of bone metabolism
- Cannabinoid receptors and the regulation of bone mass
- Natural products as alternative treatments for metabolic bone disorders and for maintenance of bone health
- Peripheral cannabinoid receptor, CB2, regulates bone mass
- Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors
- Long-chain polyunsaturated fatty acids may mutually benefit both obesity and osteoporosis
- Skeletal lipidomics: Regulation of bone metabolism by fatty acid amide family
CBD FOR PAIN
- Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain
- Sativex: Clinical efficacy and tolerability in the treatment of symptoms of multiple sclerosis and neuropathic pain
- Cannabis, pain, and sleep: Sativex Clinical Trials
- Cannabinoids for neuropathic pain
- Neuropathic orofacial pain: Cannabinoids as a therapeutic avenue
- Oromucosal delta9-THC/CBD for neuropathic pain associated with multiple sclerosis
- The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain
- Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation
- Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT1A receptors without diminishing nervous system function or chemotherapy efficacy
- Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain
- Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action
- Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
- Role of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodes
- Cannabinoids in the management of difficult to treat pain
- Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain
- CBD & THC interactions on acute pain and locomotor activity
- CBD is a potential therapeutic for the affective-motivational dimension of incision pain in rats
CBD FOR PARKINSON’S DISEASE
- Effects of cannabidiol in the treatment of patients with Parkinson’s disease: An exploratory double-blind trial
- Prospects for cannabinoid therapies in basal ganglia disorders
- Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson’s disease: Importance of antioxidant and cannabinoid receptor-independent properties
- Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson’s disease
- Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson’s disease patients
- Cannabidiol for the treatment of psychosis in Parkinson’s disease
- Therapeutic potential of cannabinoids in CNS disease
- CB2 Receptors Activation Protects against Oxidative Stress and Neuroinflammation Associated Dopaminergic Neurodegeneration in Rotenone Model of Parkinson’s Disease
- Neurological aspects of medical use of CBD
CBD FOR PRION DISEASE (MAD COW)
- Nonpsychoactive CBD prevents prion accumulation and protects neurons against prion toxicity
- Cannabidiol: A prion therapy for mice?
CBD FOR PTSD (POST TRAUMATIC STRESS DISORDER)
- Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the world trade center attacks
- Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear
- Modulation of fear memory by dietary polyunsaturated fatty acids via cannabinoid receptors
- CBD blocks long-lasting behavioral consequences of predator threat stress: Possible involvement of 5HT1A receptors
- Stress switches cannabinoid type-1 (CB1) receptor-dependent plasticity from LTD to LTP in the bed nucleus of the stria terminalis
- Mitigation of post-traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence
- Cannabinoid modulation of fear extinction brain circuits: A novel target to advance anxiety treatment
- The endocannabinoid system and extinction learning
- A current overview of cannabinoids and glucocorticoids in facilitating extinction of aversive memories: potential extinction enhancers
- Cannabinoids and traumatic stress modulation of contextual fear extinction and GR expression in the amygdala-hippocampal-prefrontal circuit
- Non-antidepressant long-term treatment in post-traumatic stress disorder
- The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: Involvement of the endocannabinoid system
- The Use of Medicinal Marijuana for Posttraumatic Stress Disorder: A Review
- CBD Modulates Fear Memory Formation Through Interactions with Serotonergic Transmission in the Mesolimbic System
- Bidirectional Effects of CBD on Contextual Fear Memory Extinction
- CBD disrupts the consolidation of specific and generalized fear memories via dorsal hippocampus CB1 and CB2 receptors
- Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report
CBD FOR RHEUMATISM
CBD FOR SCHIZOPHRENIA
- Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
- Cannabidiol as a potential treatment for psychosis
- Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia
- Medical use of cannabis. CBD: A new light for schizophrenia?
- A critical review of the antipsychotic effects of CBD: 30 years of a translational investigation
- Peripheral endocannabinoid system dysregulation in first-episode psychosis
- Cannabinoids and schizophrenia
- Antipsychotic-like effects of cannabidiol and rimonabant
- CBD monotherapy for treatment-resistant schizophrenia
- Cannabis with high CBD content is associated with fewer psychotic experiences
- Clearing the smoke: what do we know about adolescent cannabis use and schizophrenia?
- Neuronal and molecular effects of cannabidiol on the mesolimbic dopamine system: Implications for novel schizophrenia treatments
- Improved Social Interaction, Recognition and Working Memory with CBD Treatment in a Prenatal Infection Rat Model.
CBD FOR SCLERODERMA
- The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways.
- VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways.
- Cannabinoid derivatives acting as dual PPARγ/CB2 agonists as therapeutic agents for systemic sclerosis.
- Cannabis sativa as a Potential Treatment for Systemic Sclerosis.
- Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System.
- Medical cannabis: Another piece in the mosaic of autoimmunity?
- The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders.
- Targeting the Cannabinoid Pathway Limits the Development of Fibrosis and Autoimmunity in a Mouse Model of Systemic Sclerosis
- Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1.
- Cannabinoids inhibit fibrogenesis in diffuse systemic sclerosis fibroblasts.
- EHP-101, an oral formulation of the cannabidiol aminoquinone VCE-004.8, alleviates bleomycin-induced skin and lung fibrosis.
CBD FOR SICKLE CELL ANEMIA
- Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: Modulation by cannabinoids
- Cannabis use in sickle cell disease
CBD FOR SKIN CONDITIONS
- Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis
- CBD exerts sebostatic and antiinflammatory effects on human sebocytes
- The endocannabinoid system of the skin in health and disease
- Epigenetic control of skin differentiation genes by phytocannabinoids
- A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ
- Endocannabinoids modulate human epidermal keratinocyte proliferation and survival via the sequential engagement of cannabinoid receptor-1 and transient receptor potential vanilloid-1
- Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation
- Attenuation of allergic contact dermatitis through the endocannabinoid system
- Topical cannabinoid agonists. An effective new possibility for treating chronic pruritus
- The role of cannabinoids in dermatology
- Cannabidiol upregulates melanogenesis through CB1 dependent pathway by activating p38 MAPK and p42/44 MAPK
CBD FOR SLEEP DISORDERS
- Effects of acute systemic administration of CBD on sleep-wake cycle in rats
- Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults
- CBD modulates sleep in rats
- Endocannabinoid modulation of cortical up-states and NREM sleep
- Intranodose ganglion injections of dronabinol attenuate serotonin-induced apnea in Sprague-Dawley rat
- Endocannabinoid Signaling Regulates Sleep Stability
- Cannabis, Cannabinoids, and Sleep: a Review of the Literature
- Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report.
CBD FOR SPINAL CORD INJURY
CBD FOR STRESS
- Endogenous cannabinoid signaling is essential for stress adaptation
- Regulation of endocannabinoid signaling by stress: Implications for stress-related affective disorders
- Functional interactions between stress and the endocannabinoid system: from synaptic signaling to behavioral output
- Neuromodulators, stress and plasticity: a role for endocannabinoid signaling
- Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stress
- Endocannabinoids and stress
- Stress regulates endocannabinoid-CB1 receptor signaling
- Chronic Stress Impairs α1-Adrenoceptor-Induced Endocannabinoid-Dependent Synaptic Plasticity in the Dorsal Raphe Nucleus
- Endocannabinoid-mediated modulation of stress responses: Physiological and pathophysiological significance
- Cannabinoid receptor activation prevents the effects of chronic mild stress on emotional learning and LTP in a rat model of depression
- Cannabinoids ameliorate impairments induced by chronic stress to synaptic plasticity and short-term memory
- The anxiolytic effect of CBD on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
- Low-frequency stimulation evokes serotonin release in the nucleus accumbens and induces long-term depression via production of endocannabinoid
CBD FOR STROKE
- Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury
- Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism
- Cannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptamine1A receptor-dependent mechanism
- Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function
- Protective Effects of Cannabidiol Against Hippocampal Cell Death and Cognitive Impairment Induced by Bilateral Common Carotid Artery Occlusion in Mice
- Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance
- CBD reduces brain damage and improves functional recovery in a neonatal rat model of arterial ischemic stroke
CBD FOR TRAUMATIC BRAIN INJURY (TBI)
- Protective Effects of Cannabidiol Against Hippocampal Cell Death and Cognitive Impairment Induced by Bilateral Common Carotid Artery Occlusion in Mice
- Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance
- CBD reduces brain damage and improves functional recovery in a neonatal rat model of arterial ischemic stroke
CBD FOR WEIGHT LOSS