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Meds Diabetes


Vapor Accessory Addict
Staff member
Cannabis And Diabetes

Does cannabis help with diabetes treatment? Type 1 and type 2 diabetes have two completely different causes. Yet, the same herb may be helpful for both of the conditions. Though research is in its early stages, there have even been some small human trials of cannabinoid therapies as a diabetes treatment. While evidence that the herb may improve insulin sensitivity and help autoimmunity is still under review, cannabis may help patients cope with difficult diabetes symptoms.

Type 1 diabetes
Cannabis has a lot of potential in the treatment of autoimmune diseases, type 1 diabetes included. In type 1 diabetes, an overactive immune system decides to attack the pancreas. The pancreas is responsible for producing insulin, a hormone which moves sugar out of the blood and into cells.

When the immune system attacks these cells, they can no longer produce the insulin needed to regulate blood sugar. Unfortunately, type 1 diabetics are usually on life-long insulin. When the pancreas becomes too damaged, there is not much you can do other than replace the hormone that the organ makes. While cannabis therapy cannot create more insulin, the herb may be helpful for another reason. Active compounds in the plant called cannabinoids may help calm the immune system in type 1 diabetes. Calming the immune system stops your body from attacking itself, decreasing harm to the pancreas. Here’s how the herb seems to work:

Cannabis and autoimmune diabetes
Back in 2001, researchers put psychoactive THC to the test in mice with autoimmune diabetes. The mice were treated with 150mg/kg of THC. The scientists found that the mice had much lower instances of hyperglycemia and a significant decrease in loss of pancreatic insulin. They also found lower inflammatory markers in the mice. Low inflammation is a sign that the immune system is suppressed, decreasing destruction of the pancreas. Yet, 150mg/kg of THC is a lot. Fortunately, nonpsychoactive CBD also has potential. A 2008 study found that CBD delayed insulitis, the term for when immune cells attack insulin-producing cells in the pancreas. The same study also found decreased inflammatory markers. In fact, CBD treatment seemed to shift immune response to from pro-inflammatory to anti-inflammatory. This tentatively corrects an immune imbalance that contributes to autoimmune disease in animal models.

Human trials in type 1 diabetes sorely needed. But, rodent models do show that cannabis is not something to be overlooked. The herb is far from a cure for type 1 diabetes, but the potent anti-inflammatory and immune modulating properties of the herb may be highly beneficial for delaying the condition and improving the overall quality of life for type 1 diabetics.

Type 2 diabetes


Type 2 diabetes is a different beast. While type 1 is an autoimmune condition, type 2 is linked to poor carbohydrate metabolism. The body has become so inundated with sugars that the pancreas has to continue to pump out insulin to remove high levels of sugars in the blood. These sugars are stored in fat cells. Eventually, cells are so bombarded with insulin carrying sugar that they no longer respond to the hormone. This fatigues the pancreas. The organ has to keep producing more and more insulin to get your fat cells to respond. It just can’t keep up. The result is skyrocketing blood sugar levels.

Sugars come from carbohydrates. Not just candy, soda, and ice cream, but simple, refined grains like pasta, breakfast cereals, and fruit juices. Carbohydrates in these foods are broken down into glucose in the body, creating blood sugar. This is why low carbohydrate diets are so effective in those with type 2 diabetes. With a low-carb diet, you drastically limit overall sugar intake. Though, you may still need to take insulin depending on your individual condition. Here’s where cannabis comes in. Interestingly enough, cannabis aids type 2 diabetics in an entirely different way than it does in type 1. While the anti-inflammatory properties of the herb are useful in this version as well, it’s the plant’s impact on metabolism that is most beneficial in type 2 diabetes.

As it turns out, compounds in cannabis may improve insulin sensitivity.

Cannabis and insulin
There’s a lot of potential for future cannabis-based diabetes drugs. Thus far, animal models have been quite positive. A 2012 study found that CBD effectively decreased feeding in rats. The research tested three different cannabinoids, CBD, CBN, and CBG. CBG had no effect on appetite, CBN caused the rats to eat more. But CBD seemed to decrease appetite. The rats consumed less when they were treated with the compound. While overeating is far from the primary contribution to diabetes, appetite-suppressing qualities may be beneficial for those trying to majorly transform their diets as a part of diabetes treatment.

CBD has also shown potential in reducing non-alcoholic fatty liver disease. When combined with THCV, the cannabinoid cocktail successfully decreased fat buildup in the liver. The fatty liver study looked at cells cultured outside of the body, obese mice, and zebrafish. Fatty liver disease is one of the possible complications of metabolic syndrome. Metabolic syndrome is the umbrella term for a range of conditions, including diabetes, high-cholesterol, high blood pressure, fatty liver, and heart disease. All of these conditions, including fatty liver, are prevalent in those with type 2 diabetes. But, that’s not all. In two mouse models of obesity, THCV decreased glucose intolerance, improved insulin sensitivity, and increased energy expenditure. Basically, THCV kickstarted the rodents’ metabolism. This research also found that THCV restored insulin signaling in cells that were once resistant to the hormone.

This collection of strong animal evidence led British researchers to put cannabis to the test in humans. Here are the details:

A clinical trial
In 2012, British pharmaceutical company GW Pharmaceuticals tested two cannabinoids in type 2 diabetes. They gave 62 diabetes patients nonpsychoactive tetrahydrocannabivarin (THCV) and CBD. The results were positive. The patients had improved insulin response and greater pancreatic cell function. Blood glucose levels dropped, fasting insulin increased, blood pressure was reduced, and anti-inflammatory markers declined. The trial was double-blind, randomized, and placebo-controlled. The creme-of-the-crop as far as studies go. GW Pharma’s study used a drug that contained both THCV and CBD in specific ratios. The success of this trial has inspired GW Pharma to move forward with a larger placebo-controlled study.

Additional symptoms
There’s good evidence that cannabis can actually improve metabolic function and ease autoimmunity in both types of diabetes. But, that’s not all the herb can do. The plant may help patients manage some of the uncomfortable side effects of either condition. Here’s how:

Neuropathy is nerve damage. High levels of blood sugar can cause nerve damage over time, leading to painful conditions. Diabetic neuropathy can manifest in different forms, though it most commonly causes pain, numbness, and tingling in the hands, arms, feet, and legs. Both autoimmune and type 2 diabetes patients can experience neuropathy. In fact, 60 to 70% of those with diabetes experience neuropathy.

A 2015 study tested 16 diabetic patients with neuropathy of the feet. Each patient received four testing doses. They each tried a placebo, low THC, moderate THC, and high THC. Patients took a two-week break before changing doses. The results? Patients felt a dose-dependent relief from neuropathic pain with cannabis treatment. Yet, another 2009 study found something different. The clinical trial tested 30 neuropathy patients with Sativex, a GW Pharmaceuticals drug created for multiple sclerosis patients. Sativex contains a 1 to 1 ratio of THC to CBD. In this trial, the Sativex was not effective in reducing neuropathic pain.

Both of these studies provide conflicting results, indicating that there is a lot we still need to learn about cannabis treatments. In animal models of diabetic neuropathy, cannabis has effectively improved nerve response. In fact, treatment with cannabis extract restored thermal pain perception in rats without worsening blood sugar levels. But, as always, more human research is needed.

Diabetes can also damage your eyes. Diabetic retinopathy occurs from damage to the small blood vessels behind the retina. It can eventually lead to blindness, and is the leading cause of blindness in people aged 20 to 64. The longer you have diabetes, the more likely you are to suffer from this form of ocular degeneration. Fortunately, cannabis may be able to help this complication as well. 2006 research found that CBD may protect the eye from “a growing plethora of leaky blood vessels”. In diabetes, it’s not uncommon to experience ischemia, where different organs in your body are not receiving enough oxygen.

This lack of oxygen causes blood vessels in your eyes to try to create new blood vessels to solve the problem. Unfortunately, it doesn’t work out so well for them. Very simply explained, under all of this stress, special pumps that help regulate communication between nerve cells in your eyes begin to fail. This leads to eye troubles.Cannabinoids are trying to ease the situation on both sides. They help save the neuron and, at the same time, make sure the microglial cells [an immune cell of the central nervous system] stay in microglial form. The cannabinoid’s strong antioxidant properties help reduce damage from stress which causes ocular nerve cells to fail.

Potential strains for diabetes
Unfortunately, it can be difficult to find cannabis products high in both THCV and CBD. Yet, there are some strains out there that you might want to consider. Until we either have strains bred specifically for those with diabetes or we have a cannabis-based drug, canna-curious patients are left with a handful of herbal options.

Here is a brief list of high THCV and high CBD cannabis strains:

  • Charlotte’s Web Hemp Oil (this is a high CBD product legally available for any U.S. resident to purchase online, though the providers make no medical claims.)
  • Harlequin (high CBD)
  • Durban Poison (high THCV)
  • Blue Dream (high THCV, but check testing data as there are two common phenotypes for this strain.)

Though cannabis is no replacement for a healthy (perhaps preferably low-carb) diet, exercise, sleep, and stress management, the herb has therapeutic potential. Fortunately, clinical trials testing cannabis as diabetes treatment are currently underway. We look forward to their results.
While I would still make sure you follow through with doctor's orders, this sounds promising. :twocents:

CBD for Diabetes – The Uprising Cure of 2018

The prevalence of diabetes in the United States is truly shocking.According to the CDC, over 90 million Americans either have diabetes or prediabetes. Overall, more than 30 million Americans (over 9% of the population) have the condition. Meanwhile, pre-diabetes is a condition that can lead to type 2 diabetes within five years if untreated.

“When I found out I had diabetes, my response was shock and fear. I had tried many different programs. I now combine a stable diet with CBD. I have lost 50 pounds, my blood sugars are within normal, and I am off my medication.” William T, IL

Type 1 diabetes accounts for just 5% of cases – if you have this condition, it means your body’s immune system is destroying the cells that release insulin. In effect, it prevents the body from producing insulin and without this crucial substance, your cells won’t be able to absorb glucose (sugar) which is necessary to produce energy.

Type 2 diabetes is overwhelmingly the most common form, and it can develop at any age. If you have this condition, it means your body can produce insulin, but it is unable to use it properly (this is otherwise known as insulin resistance). When the condition gets worse, your pancreas will create lower amounts of insulin, which is known as insulin deficiency.

Dealing with diabetes as soon as possible is crucial. Otherwise, you could suffer from serious medical conditions such as kidney failure, blindness, stroke, heart disease, and even foot or leg amputations! There are dozens of diabetes medications on the market such as Prandin, Glucotrol, and Starlix, but they pose serious side effects and could result in high or low blood sugar if not used properly. In contrast, studies show that CBD is at least as effective as these meds, with little to no side effects.

Is CBD the Best Diabetes Treatment?
It is too early to tell, but early research paints an exceedingly promising picture of CBD being a quality diabetes treatment. If you have diabetes, it completely changes your life as everything revolves around ensuring you manage the condition in advance. For example, if you plan on driving, you need to check your blood glucose levels two hours beforehand and every two hours on the road.

Mood changes and depressive illnesses are also more common in individuals who have long-term medical conditions ,and people living with diabetes are no different. It is normal to feel a total loss of control, which leads to heightened anxiety. Interestingly enough, CBD can help you with anxiety disorders too!

Before we get to the science, here is a quick overview of the multitude of ways in which CBD can help diabetes sufferers:

  • It stabilizes blood sugar levels.
  • It has neuroprotective effects that stop the inflammation of nerves, and it also helps reduce the pain of neuropathy.
  • It helps calm restless leg syndrome (RLS), a common diabetes symptom.
  • It lowers blood pressure.
  • It acts as a vasodilator, which is a medical term denoting a capacity to improve circulation by keeping blood vessels open.
What Does Science Say About CBD?
Doctor Raphael Mechoulam, one of the greatest organic chemists in history, is a pioneer in the research of cannabis’ medicinal properties, and it t is no surprise to learn that he is heavily involved in the search for a marijuana-related treatment for diabetes. He has discovered that CBD receptors occur throughout the body, and the pancreas is one of the organs where he found these receptors to be especially prevalent.

Bear in mind that the pancreas is responsible for regulating blood glucose levels via the systematic release of insulin. Therefore, in theory, the consumption of CBD should help control insulin levels and ultimately prevent diabetes. Of course, it is not a miracle cure — you still need to have a sensible, low sugar diet.

One of the most important studies relating to marijuana and diabetes treatment appeared in the American Journal of Medicine in 2013. It was the result of a 5-year study on the effects of weed on insulin resistance and fasting insulin. It looked at over 4,600 patients, almost half of whom had never used weed, and the researchers discovered that current users of marijuana had 16% lower fasting insulin levels and 17% lower insulin resistance levels than those who had never consumed weed before.

The insulin resistance (IR) aspect is especially interesting. As we previously mentioned, IR relates to type 2 diabetes. In the study, it was found that those who still used marijuana had a mean IR of 1.8. In contrast, past users had an IR of 2.2 while non-users had the highest IR of all at 2.5. Current users also had by far the lowest levels of blood glucose on average.

Can You Use CBD As a Long-Term Treatment for Diabetes?
The short answer is ‘yes’! Unlike THC, CBD is non-intoxicating which means you won’t fail a drug test, won’t get high, and should be able to order it online although some states have restrictions on the sale of CBD. The key is to find the highest quality CBD products on the market, and you can see tons of reviews to find out which CBD product can work for you.

A lot of commercially available marijuana strains (i.e. strains that are for sale in dispensaries) are laden with THC, with the CBD having almost been bred out of the plant. As such, you should focus on CBD-rich strains such as Charlotte’s Web and ACDC. These are filled with CBD and virtually zero THC. Also, the amount you take depends entirely on individual need – some people feel positive effects with as little as 10mg of CBD a day, while others need up to 200mg. We advise you to start low and gradually increase your dosage until you feel the effect you desire.
CBD Oil May Eliminate The Need For Insulin Shots
There are more than 100 million Americans that have diabetes.

The federal government claims there are more than 100 million Americans either living with diabetes are or on the verge of becoming full-blown diabetic. This means millions more people will be diagnosed with this condition within the next five years, according to the Centers for Disease Control and Prevention.

Thos unfortunate souls who have this disease are unable to produce insulin in the same way as a healthy individual. Basically, the pancreas either ceases insulin production or no longer provides the body with optimal output. Either way, man-made medicines are typically employed to keep the person alive.

The treatment program for diabetics can range from modest changes to regimented treatment. Some can get away with changing their diets and incorporating exercise into their daily routine, while others must lean on regular prescription insulin shots to stay healthy. Anyone who has self-administered insulin will tell you — it’s no picnic.

But there is now a small body of evidence suggesting that medical marijuana, specifically its non-intoxicating compound cannabidiol (CBD), may eventually eliminate the need for insulin shots.

There are two kind of diabetes. Type 1 is when the body no longer produces insulin. A virus is typically responsible for causing this version. It is said that around 5 percent of the population has Type 1 diabetes, appearing mostly in children and young adults.

There is also the more common Type 2 – affecting around 95 percent of the population — in which the body still produces insulin, just not enough for proper function. This version is brought on by a variety of factors, including a high sugar diet and obesity. Genetics also play a role.

Most people diagnosed with diabetes are doomed to regularly prick their fingers to monitor their blood sugar levels. It may also be necessary for them to self administer insulin shots (Metformin or Avandia). But some medical professionals believe that CBD oil, which is produced by extracting nutrients from the cannabis plant, might be able help patients maintain healthy glucose levels.

Dr. Raphael Mechoulam at the Hebrew University of Jerusalem says CBD receptors, which are found all over the human body, are highly prevalent in the pancreas – where insulin is made. His preliminary studies have suggested that feeding these receptors with high doses of CBD may stimulate insulin production without prescription drugs.

Although these results have not been proven without a shadow of a doubt, the concept has inspired additional funding for diabetes research in the United States.

There is also evidence that CBD’s anti-inflammatory properties could help treat underlying medical conditions associated with diabetes. The compound is beneficial in improving metabolic function and repairing nerve damage – both of which can have a nasty affect on diabetics.

But when considering CBD oil, it is important to discuss it with a medical marijuana professional. Not all oils are created equally, so open dialogue with dispensary staff is a crucial first move. Some diabetics have experienced success with CBD, while others not so much. It is really about finding the medical marijuana product that works best for the individual.
Diet alone is the major factor with diabeties..
Governments happy to spend literally million on drugs alone, let alone all the other costs to the system because of this.. all because we are eating the wrong food.. it's fucking insane to me..

This is why im paleo.. I made my mother go paleo a few months ago, as she was fairly overweight, and borderline diabetic...

She went to the doctors again a few days ago, after losing 2 stone... amd her blood sugar is now normal... happy days.. the doctor was very impressed that she had done all this with no drugs or help..

So the lesson here is simple, if your diabetic or borderline, stop eating the poisens your governments are feeding you.. it's your choice..
Refined sugar is evil.. bleached bread, all dairy..
It's all killing you..

I cant believe people drink milk.. do you know what's in it..??? Google it.. and anyway apart from all the gm chems amd antibiotics, it's just so far from natural it's unreal..
How many other animals suckle milk for their whole life...??? Let alone from another species..
And have you actually seen a cow.. and how big they are.. you think you need that much nutrients in your life..

And dont get me started on potatoes...
I'll stop now...
Study: Cannabis Protective Against Diabetes Among Those Overweight

Quebec, Canada: A history of cannabis use is associated with lower fasting insulin levels in obese subjects, according to data published in The Journal of Diabetes.

Canadian researchers assessed the relationship between cannabis consumption and fasting insulin levels and insulin resistance in a nationally representative sample of over 129,000 adults. They reported that both current and past cannabis use was associated with significant and persistent changes in insulin levels in obese subjects compared to non-users. However, these changes were only evident in overweight subjects.

"[W]e found that lifetime marijuana use is significantly associated with lower fasting insulin and HOMA-IR (a measure of insulin resistance) in obese individuals," authors concluded. "We also found that, a long time (> 10 years) after cessation, former users showed significant lower levels of fasting insulin and HOMA-IR scores than did never users, independent of their frequency of use in the past."

The data is consistent with prior observational studies finding that those with history of marijuana use possess more favorable indices related to diabetic control than do non-users.

For more information, contact Paul Armentano, NORML Deputy Director. Full text of the study, "Lifetime use of marijuana use in relation to insulin resistance in lean, overweight, and obese US adults," appears in The Journal of Diabetes. Additional information specific to cannabis and diabetes is available from NORML.
Marijuana and Diabetes: Treating Diabetes with Cannabis

Over a decade ago, we published a brief article here at DiabetesMine about how cannabis (yep: pot, grass, weed, ganja) can be used to treat diabetes, and people have been flocking here ever since to learn more.

Now that it's (mostly) legal, we’ve taken a broad look at the topic and growing body of research (OK, much of it in animals) showing that cannabis can have a number of positive effects on diabetes.

Marijuana for Diabetes

One of the first big reports ever published by the American Alliance for Medical Cannabis (AAMC) purported that cannabis can have the following benefits for PWDs (people with diabetes):
  • stabilizing blood sugars (confirmed via "a large body of anecdotal evidence building among diabetes sufferers")
  • anti-inflammatory action that may help quell some of the arterial inflammation common in diabetes
  • "neuroprotective" effects that help thwart inflammation of nerves and reduce the pain of neuropathy by activating receptors in the body and brain
  • "anti-spasmodic agents" help relieve muscle cramps and the pain of gastrointestinal (GI) disorders
  • acts as a "vasodilator" to help keep blood vessels open and improve circulation
  • contributes to lower blood pressure over time, which is vital for diabetics
  • substituting cannabis butter and oil in foods "benefits cardiac and arterial health in general"
  • it can also be used to make topical creams to relieve neuropathic pain and tingling in hands and feet
  • helps calm diabetic "restless leg syndrome" (RLS), so the patient can sleep better: "it is recommended that patients use a vaporizer or smoked cannabis to aid in falling asleep"
Evidence for all of this still stands, and has in fact been corroborated and built upon in the past decade.

Research on Diabetes and Cannabis

While there’s some conflicting evidence on marijuana’s role in delaying the risk of developing type 2 diabetes, research shows it is beneficial indeed for those already diagnosed with either type 1 or 2, and especially for those who suffer complications.

A milestone study published in the American Journal of Medicine in 2013 concluded:
  • cannabis compounds may help control blood sugar
  • marijuana users are less likely to be obese, and have lower body mass index (BMI) measurements -- despite the fact that they seemed to take in more calories
  • pot smokers also had higher levels of "good cholesterol" and smaller waistlines
"The most important finding is that current users of marijuana appeared to have better carbohydrate metabolism than non-users. Their fasting insulin levels were lower, and they appeared to be less resistant to the insulin produced by their body to maintain a normal blood-sugar level,” Murray Mittleman, associate professor of medicine at Harvard Medical School and the lead researcher told TIME magazine.
In 2014, a “summary of the promising epidemiological evidence” on marijuana in the management of diabetes published in the Natural Medicine Journal also concluded that in thousands of subjects, past and current marijuana use was associated with lower levels of fasting insulin, blood glucose, insulin resistance, BMI, and waist circumference.
And in 2015, Israeli researchers at the Hebrew University of Jerusalem released a study showing that the anti-inflammatory properties of cannabidiol (CBD), a compound found in cannabis, could effectively be used to treat different illnesses including type 2 diabetes.
There’s also compelling scientific evidence that cannabis can aid in treating diabetes complications, for example eye disease; cannabis reduces the intraocular pressure (fluid pressure in the eye) considerably in people with glaucoma, which is caused by conditions that severely restrict blood flow to the eye, like diabetic retinopathy.
Pretty powerful stuff!

Why Medical Marijuana?

When most illicit substances are frowned upon, why is there so much talk about marijuana as medicine, that can actually be good for you?

The linchpin seems to be something called the endogenous cannabinoid system, named after the plant that led to its discovery, which is “perhaps the most important physiologic system involved in establishing and maintaining human health,” according to NORML, the National Organization for the Reform of Marijuana Laws, based in Washington DC.

They explain: “Endocannabinoids and their receptors are found throughout the body: in the brain, organs, connective tissues, glands, and immune cells. In each tissue, the cannabinoid system performs different tasks, but the goal is always the same: homeostasis, the maintenance of a stable internal environment despite fluctuations in the external environment… Cannabinoids promote homeostasis at every level of biological life, from the sub-cellular, to the organism, and perhaps to the community and beyond.”
Therefore NORML and other marijuana advocates and supporters “believe that small, regular doses of cannabis might act as a tonic to our most central physiologic healing system.”

How Can Marijuana Help Your Diabetes?

So let’s say you were using marijuana, or wanted to try it. What would the effect be on your diabetes?
A number of PWDs report that with regular use, they see lower blood sugar levels and reduced A1c results over time. The existing scientific evidence shows that marijuana has an effect on improving insulin resistance -- helpful for people type 2 diabetes, but generally not for type 1s. For them, there’s little more than anecdotal evidence to go on.

However, as mentioned, there is a whole body of evidence showing that marijuana is effective in treating eye disorders, chronic pain, sleep disorders, and a number of other ailments often associated with diabetes. So if you are living with one or more complications of diabetes, marijuana may very well ease your pain or slow the progression of the disorder you’re living with.

The area of mental health is a big one for marijuana, as it has been shown to effectively treat everything from clinical depression to post-traumatic stress disorder. Why is this? One answer may come from a study published in February 2015, showing that marijuana use in animals helped restore brain levels of endocannabinoids -- which affect emotion and behavior, and have been linked to reduced feelings of pain and anxiety, and increased feelings of well-being.

Of course, some people with depression will not do well on marijuana, as it can also increase feelings of anxiety and paranoia in some people.

The biggest risk of marijuana use with diabetes is probably hypoglycemia; there are a lot of concerns that PWDs’ glucose levels will drop, unnoticed by the patient until they are in dangerous territory.

So in other words: marijuana *could* help you reduce blood glucose levels, feel better, more relaxed and pain-free, but you also need to be careful.

The only consensus among the Medical Establishment on this seems to be that “more research is needed.”

Is It Legal?

Well, that depends.

Recreational use of marijuana is still a crime most everywhere in the United States, with the exception of Alaska, Colorado, Oregon, Washington and the District of Columbia (DC).

However, medical use of marijuana is gaining acceptance fast. As of this writing, it is now legal in 23 states and DC.

The American Alliance for Medical Cannabis website offers a great overview of the particular laws in each state.

For example in the state of California, with a medical clearance, it is now legal to have up to 8 ounces of dried marijuana and 6 mature or 12 immature marijuana plants in your possession - wow!

So how do you get a medical marijuana card that allows you legal access to medicinal cannabis? There are generally three basic requirements:
  1. proof of residence of the state or territory in which it is legal
  2. an eligible "serious medical condition" -- definitions differ by state (California for example adheres to the Americans with Disabilities Act of 1990 that calls out any chronic condition "that either substantially limits a person’s ability to conduct one or more major life activities" and specifically lists diabetes. Elsewhere, eligible conditions include complications of diabetes like eye disease or chronic pain from neuropathy)
  3. clearance from a doctor willing to prescribe it to you

Anecdotally, we know that in the San Francisco Bay Area, it’s fairly easy to find a physician willing to sign the papers and send you to a local dispensary to choose your favorite variety of Mary Jane. There are also now delivery servicesin many states, where a truck pulls up in front of your house, just like the pizza man.

CBD Oil for Diabetes

As marijuana is becoming increasingly legal and socially acceptable, so are its related hemp byproducts. CBD oil in particular is getting a lot of attention as a health aide. But should you use it if you have diabetes?

What is CBD Oil and How Is It Used?

Cannabidiol, better known as CBD oil, is made by extracting the essence from the cannabis plant, and diluting it with a “carrier oil” like coconut or hemp seed oil.
It is credited with alleviating symptoms of a number of ailments, including chronic pain, anxiety and depression.

The pure oil form is typically taken by placing the desired quantity of drops under your tongue using the dropper and holding it there for a minimum of 60 seconds -- to allow for absorption via the blood vessels under the tongue. Once 60 seconds has passed, you swallow the CBD oil.

How much to take depends on the illness you’re hoping to treat, but generally runs between 2.5-20mg per day.

Is CBD Oil Good for Diabetes?

Emily Kyle, a Registered Dietitian and experienced Holistic Cannabis Practitioner in upstate New York, tells us that just like with any other over-the-counter supplement or medication, there are obvious concerns when using CBD oil if you have type 1, type 2, or gestational diabetes. Those concerns can range from the type and quality of the product being used to various potential side effects.

The biggest concern lies in the possibility of a cannabinoid-drug interaction for those who are taking prescribed medication and/or insulin to manage their diabetes.
Unfortunately, clinical studies in humans on the direct effect of CBD oil on blood sugar is lacking, likely due to the illegal status of marijuana, which is currently seen as a schedule 1 drugTrusted Source in the eyes of the Federal Government, Kyle says.

“What we do know is that the endocannabinoid system plays an important role in how the body responds to insulin, increasing or decreasing insulin sensitivity. This is critically important for those who are taking insulin because it could mean that their blood sugars could rise or fall unexpectedly, making tight control more difficult to achieve,” she says.

“Anecdotally, I have had clients who exhibit completely different response reactions to CBD oil use. One client told me it dramatically decreased their blood sugar within a matter of minutes, which is potentially very dangerous. Other clients notice no effect on blood sugar at all. This is attributed to the uniqueness of each person’s endocannabinoid system and their personal endocannabinoid tone.”

To learn more, including Kyle’s recommendation for the best CBD oil to choose if you have diabetes, see the full story here: Ten Questions Answered on CBD Oil and Diabetes.

Diabetes and Marijuana: Doctors Say...

Endocrinologist and Type 1 patient herself Shara Bialo in Rhode Island tells us that as a pediatric endocrinologist, she primarily gets questions from the teenagers she treats:
They all ask the same thing: "I heard that marijuana can be good for lowering blood sugar. Is that true?"

I have to handle this question carefully, so I start by reminding them that marijuana is not legal where I practice. But I also explain that it has been shown to improve insulin resistance, meaning it is likely to be more helpful in type 2 diabetes.

There are also no studies of this nature conducted on minors. I also then bring up the other problems -- that getting high can cause the "munchies" (and usually not for low-carb foods!) and that the fuzzy mental state can lead to inaccurate insulin dosing calculations or forgotten doses altogether.

I then wrap up with the suggestion that there is not enough data to prove that marijuana is more safe than harmful, at least as far as diabetes is concerned. Most are okay with this answer, if not a little disappointed ;).


Certified Diabetes Educator (CDE), Author and Type 1 patient himself Gary Scheiner in Pennsylvania says he offers these words of caution to his patients:

The latest stats show that nearly 30% of people with diabetes age 16-30 have at least tried marijuana, so it is a common concern. While it does not have the strong link with cancer than tobacco has, it can have detrimental effects on cognitive function and can affect diabetes control adversely by:
  1. Impairing judgement (resulting in inaccurate insulin dosing, for example)
  2. Increasing appetite and leading to binge eating
  3. Contamination (marijuana is not regulated) with impurities such as lead can contribute to early-onset kidney disease

Susan Weiner, named Diabetes Educator of the Year in 2015, who’s also known for her books and columns on diabetes care, tells us that most healthcare professionals shy away from even discussing this topic, but they really shouldn’t:

Most health care providers are “skeptical” and “cautious” and probably a bit nervous about recommending marijuana use for people with diabetes. Although there are some encouraging studies about the benefits of marijuana use insulin levels, weight management, lowering blood pressure (and a number of other possible benefits) the research is conflicting. More properly conducted studies and evidence based research is needed before cannabis can be recommended for most people with diabetes. We also have to determine if additional conditions such as heart disease would rule out using marijuana as part of the diabetes treatment plan. In addition to the these concerns, determining proper dosage remains problematic.

Over the years very few of my patients have talked about marijuana use as it relates to their diabetes care. However, many have told me they use marijuana recreationally… I think it’s imperative to have a very open dialogue with my patients about everything related to their health and diabetes management.

I’m actually concerned if my patient is uncomfortable discussing this or any other topic with their endocrinologist or primary care provider. I always tell my patients that they are the leader of their own healthcare team, so their concerns and suggestions are key.

To ignore the topic is doing a disservice to the patient, if it is something they would like to discuss. In order to approach sensitive topics (for example: marijuana use, sexual dysfunction or health literacy issues) I ask open-ended questions, use motivational interviewing techniques and actively listen to what the patient is saying. Although we providers often want to educate and impart as much knowledge as possible to our patients, it’s more important to listen to what’s important to them.


Dr. Korey Hood, Professor of Pediatrics, Psychiatry and Behavioral Sciences at Stanford University School of Medicine, explains:

While I am part of the Medical Establishment as a PhD clinical researcher and licensed psychologist, I do not prescribe or administer medical care. But I am very involved in multidisciplinary care of people with diabetes as well as research on prevention and treatment. I perceive the general attitude of diabetes care providers about marijuana use in people with diabetes is that they should not use it recreationally.

From my experience, the group of patients most likely to ask about it are teenagers and young adults. My approach is to follow these guidelines: a) it is generally best to start discussing substance use with pre-teens (whether defined by chronologic age of around 12 or developmental level if more mature than most other 11-year-olds, for example), b) it is better to provide information and education aimed at prevention than a “just say no” approach, which does not work, and c) always review the legal guidelines depending on the state I practice in (currently California). I very much support an effort to discuss early and often and provide factual information.

I always attempt to have open and honest discussions about marijuana use (and other substances, particularly alcohol). I typically review the following, often in this order:
  1. It’s important to know the laws in your state. Most states have not legalized recreational use while a number have medical marijuana laws. Decriminalization shouldn’t be confused with legalization. If I am talking to youth under 18, I usually emphasize this point more than I would with older adults.
  2. But if planning to use, best to do it as responsibly as possible. “Responsible” use means moderation and attempting to avoid use until the brain is fully developed (around age 25). I always mention there are studies that show even recreational use can have negative effects on brain activity and moods. These effects are worse for daily users. There are also data, mostly in studies of men, to note the negative effects on fertility. I try to review what we know (and don’t know) so that any use is engaged in with eyes wide open.
  3. From a diabetes perspective, I usually focus on the indirect effects of marijuana use. While I am not aware of laboratory data on direct effects of THC(the main psychoactive ingredient in cannabis) on blood glucose levels, I focus on the indirect effects of getting the “munchies” and typically not making good decisions regarding insulin or other medications after marijuana use. The typical scenario reported to me is that there is overeating and blood sugars end up high. Occasionally there is an over-bolus but that seems to be less common.
  4. I also talk about ways to ingest marijuana and that there are more dangers associated with smoking, versus eating, versus using vaporizers. Smoking tobacco/cigarettes is one of those areas that I plead with people with diabetes (and those without as well) to not ever do. Smoking marijuana can have negative effects as well. I don’t recommend a way to do it but do discourage smoking in any form.
  5. Finally, I always mention that “responsible” use means not driving after any use, having someone around you who knows you have diabetes and is not under the influence, and making sure someone around you knows how to treat extreme lows or highs if necessary.
Marijuana and Diabetes: Patients Speak Out

C.W., a 36-year-old man in California, shares:

I was diagnosed with type 1 diabetes in my freshman year of college (at 18 years old, 18 years ago). I used marijuana recreationally throughout college and for about six years thereafter, during which I became aware of some of the research as to cannabinoids and their effects on the progression of complications from diabetes (specifically Diabetic RetinopathyTrusted Source.)

I ceased my use of marijuana for a number of years in my late 20s and early 30s, and noticed during that time that my diabetes control deteriorated noticeably -- more hypoglycemic and hyperglycemic events, and my A1cs went from the mid-7s to the mid-8s. I also began to develop early signs of Diabetic Nephropathy.

I've only recently (for the last 8 months or so) resumed my marijuana use, this time at the advice of a doctor, and with an official recommendation.

My kidney function has improved, and so has my control over blood sugars. I attribute this to a number of factors, including a reduction in anxiety over blood glucose numbers which led to over-corrections in both directions, improvements in blood pressure (probably at least partly due to the reduced anxiety), and the hypothesized effects of CBD from the marijuana reducing oxidative stress on my nervous and circulatory systems.

My A1c has improved significantly -- my last one was 7.3%, and assuming my meter/CGM readings are accurate, the next one should be in the mid-6s.

In terms of risks, the major concern voiced by my doctor was a potential lack of ability to feel oncoming hypoglycemia. Not really an issue for me, personally, as I have a CGM, and I put effort into staying aware of any effects that I might misconstrue.

I should also note that even for recreational users, the potential for causing hypoglycemia is a lot less with marijuana than with alcohol, since pot does not have the same suppressive effect on hepatic gluconeogenesis (metabolic processing of glucose) that alcohol does. One other thing (not mentioned by the doctor, but I keep an eye on) is the "munchies" that some strains of marijuana can cause. I don’t want to go on a carb binge, so I keep low- or no-carb snacks around in the event of this, although the CBD-heavy strains that I usually use don't cause the munchies the same way that THC-heavy strains of marijuana do.

I'm sure pot isn't for everyone, as almost nothing is cut-and-dried when dealing with medical issues, and potential side effects can be difficult to predict. Some people may have other conditions which would contraindicate marijuana use.

However, for people who live in places with a Medical Marijuana program (or, in the case of CO and WA, legalized recreational use for everyone), it may be worth considering as an adjunct to their management regimen. Also, given that a large number of PWDs also suffer from other comorbid autoimmune conditions for which marijuana may be indicated as a treatment, it's worth noting that taking it for something else may as a side effect help them to improve their D-management.

A.C., a 40-year-old woman with T1D in the Midwest, shares:

I marked my 32nd dia-versary in January 2016. I use shots only at this time -- no pump or CGM.

I experimented with marijuana in college and use it recreationally as an adult. It's not a regular part of my life, but I enjoy it when in a safe, controlled environment.
Effects are tricky to describe because there are multiple layers depending on the type of marijuana used. Tincture (liquid extract) is more of a body high (makes you relaxed) -- but you can totally function. Edibles have the same effect, and smoking seems to be more of the “head high.”

The smoking component makes me process my thoughts differently, kind of giving me the ability to think freely. All of these factors are dependent on my environment (who am I with, are we brainstorming new ideas or just trying to relax). It doesn't make me particularly hungry, but when it does, I eat healthy snacks (handful of cashews, hummus and carrots or fresh fruit).

I've noticed on multiple occasions that pot lowers my blood sugar -- not dramatically where I’ve had an emergency but just overall lower numbers. In fact, I mentioned a particular episode with my dietitian when I changed from NPH & Regular to Lantus and Novolog. He too, happened to be a T1D and said it had the same effect. He also mentioned purchasing certain kinds of pot because he knew it had that effect on him.

The dietitian conversation was sort of spontaneous; I've never discussed this outright with my doctor or CDE because it's illegal in the state of Oklahoma.

I would gladly sign up for a clinical trial on marijuana use and diabetes should one exist. But experts tell me the cost of research trials with "illicit" drugs is far too steep because of all the liability issues.

Marijuana & Diabetes Resources

National directory of medical marijuana dispensaries

“Top 5 Benefits of Cannabis for Diabetes” from Sensi Seeds

Cannabis and Diabetes Facts, from Diabetes UK

Diabetes & Cannabis Research Overview, from NORML
Came across this article this morning while doing some research...

Canadian Study Finds CBD Helps Diabetic Foot Ulcers

Circulatory issues are a problem for everyone in our increasingly sedentary society. Have you ever calculated how much time you spend sitting? If you work in an office, you clock about eight hours per day at a desk. Maybe ten. If you drive to work or take public transit and commute, you can add another 1-2 hours per day of sedentary positioning. After dinner, and tired from the day, most of us head to the couch to watch TV for an average of 2-3 hours before bed.

That adds up to as much as 13-15 hours per day of low to no physical activity. The average American sleeps about 6-7 hours per night. That means we are only potentially active on average, for about 2-3 hours per day. And our bodies aren’t biologically designed for that kind of lifestyle.

The loss of circulation to extremities is a severe health problem for individuals with Type I or Type 2 Diabetes. And more common with people diagnosed with Diabetes for a variety of reasons. First, the bloodstream’s high glucose levels (sugar) lead to a thickening of the blood. That deposits more plaque that narrows the pathways of major arteries and veins. It restricts the blood flow (particularly to extremities like the legs and feet).

The loss of efficient circulation also impacts organ function for patients with diabetes. With a lower blood supply, the kidneys and liver can become compromised. Major organ functioning is also impaired by glucose (sugar), impacting the pancreas and preventing cardiovascular issues like an increased risk of heart attack and stroke.

What Causes Leg and Foot Ulcers for Patients With Diabetes?​

Whenever your body is fighting off a virus or bacterial infection, it relies on the bloodstream to carry white blood cells. Leukocytes are the scientific name for white blood cells, and they are the chief defenders or security guards of the human body. Whenever there is an infection, the brain triggers an immune system response that sends more leukocytes to the area of disease. That’s how the body fights off infection.

One of the problems that occur when blood circulation is compromised is an impact on immune system functioning. You’ve probably heard that people who have diabetes are more prone to infections. This stems in part from issues with healthy blood circulation.

When circulation is a problem due to restricted blood flow, the body can’t deliver as many leukocytes to infection areas. All it takes is one small cut to the leg or foot to become infected. In a person who is not immune-compromised, the infection can clear up with wound care and antibiotics. But oral antibiotics also rely on the bloodstream for delivery throughout the body, and they can be less effective for people with diabetes.

Peripheral neuropathy can cause muscle weakness and loss of reflexes. This changes how a person walks and leads to deformed feet and conditions like hammertoes and Charcot’s foot. Diabetic ulcers develop when there is uneven pressure or friction on feet or ankles. Numbness from circulation loss makes it hard to detect pain in the area as well.

Infections Are Hard to Resolve for Individuals Who Have Diabetes​

When the body cannot heal a wound and delivering white blood cells to the infection site is compromised by circulatory issues, the wound does not get better. In fact, the tissues in the area of the wound site can become necrotic. Gangrene can set in. When a severe infection happens to a person with diabetes, ulcers like look like open wounds can appear. And they are extremely difficult to heal because the immune system is compromised.

When a severe infection cannot be resolved and gangrene has been diagnosed, the next step is removing the necrotic tissue. This can include amputation of toes, excising tissue in the infected area, or possible leg amputation. Amputations are performed only in the most challenging situations when an infection will not resolve. And when the patient is at risk of systemic spread of the disease throughout the body and bloodstream, which can lead to sepsis, heart attack, or stroke.

Intractable Ulcers Can Be Life-Threatening When They Do not Heal.​

An intractable ulcer for a patient with diabetes refers to a wound that will not heal. Patients can receive oral and IV antibiotics in varying degrees of strength to try to address the infection. But as diabetics can be severely immune-compromised, it doesn’t always work.

Amputation is a last resort for patients with diabetes because it presents other health risks. Just as the patient cannot heal from the original foot or leg ulcers, major surgery can exacerbate symptoms. And contribute to a more severe infection. Often patients are required to be on home IV infusions of strong antibiotics for weeks after surgery.

Finding a better way to treat diabetic leg ulcers is a high priority in the medical community. Did you know that 34.2 million Americans are living with diabetes? And approximately 1 in 3 Americans have pre-diabetes (high risk to develop chronic disease). Just under 80,000 people worldwide die from complications from diabetes annually.

Is Topical CBD a New Approach to Healing Diabetic Foot and Leg Ulcers?​

A new medical study from Toronto, Canada, has created hope and the potential to treat diabetic ulcers with CBD topical creams successfully. In Canada, both medical and adult-use cannabis is legalized at the federal level. This allows medical research into chronic diseases and cannabis therapeutics applications to progress unhindered, unlike the United States. Both fundings for cannabis research and access to cannabis for clinical studies is restricted.

The research conducted by the Canadian scientists was recently published in the International Wound Journal. The clinical trial involved two patients who had persistent leg ulcers. The clinical trial results are very encouraging and offer new hope for patients diagnosed with diabetic neuropathy and ulcers.

The clinical trial involved the application of a blend of cannabinoids, terpenes, and flavonoids. The patients were seniors with low immune system functioning and circulatory issues. The ulcers that inflicted both patients were treatment-resistant. Physicians had exhausted all other approaches to curing the ulcers for the patients who were facing systemic infections.

One patient saw a complete wound closure within 74 days of treatment with the proprietary blend of terpenes, cannabinoids, and flavonoids. The second patient saw complete wound healing after 77 days. Both patients reported relief of pain in the ulcerated wound areas and surrounding tissue.

What Does the New Research Mean for Patients with Diabetic Foot Ulcers?​

In the not so distant future, hospitals, long-term care facilities, and home healthcare teams may be able to prescribe and administer the breakthrough treatment. One of the most beneficial aspects of a topical solution is that it presents no secondary infection risk to the patient.

Instead of unsuccessfully fighting diabetic ulcers to the extent that the tissue becomes necrotic (dead or gangrene), requiring removal, this presents a new treatment possibility. One that could save lives and prevent invasive surgical procedures like amputations in the future for patients with diabetic neuropathy and treatment-resistant ulcers.

‘Heavy’ Cannabis Use in Women Linked to Lower Rates of Diabetes: Study

Cannabis is banned in India, but its widespread use in medicine, science, and the spiritual landscapegives it unbridled longevity. Adding to this is a new research that shows female adults, who use cannabis “heavily,” have a lower risk of developing diabetes.

Diabetes is a health condition that results from one’s blood glucose — or “blood sugar” — being too high. As of 2017, 72.9 million people in India had diabetes.

Published in Cannabis and Cannabinoid Research earlier this year, the study looked at 15,000 participants in the U.S. The researchers determined the participants’ “diabetes status” by examining levels of plasma glucose, fasting blood glucose, or hemoglobin A1C levels. They defined smoking cannabis fewer than four times a month as “light” use, and four or more times as “heavy” use.

The results showed that heavy use made female users less likely to be diagnosed with diabetes, as compared to the part of the female population that didn’t use cannabis. They found light usage among female participants to have no bearing on diabetes diagnoses.

Interestingly, the researchers didn’t find any links between cannabis use — whether heavy or light — with diabetes risk among male participants.

Experts haven’t been able to determine the exact reason behind the varying impact of cannabis use on different sexes, but they have a theory. Two key compounds of cannabis — cannabidol and delta-9-tetrahydrocannabidol — “stimulate receptors in the endocannabinoid system that result in improved glucose disposal,” an article on Neuroscience News explains. The endocannabinoid system is a web of neurotransmitters and receptors found in the nervous system that regulates different biological processes. The function of glucose disposal is one of them. Since the endocannabinoid system, which is impacted by cannabis use already works differently for different sexes, the end-effect automatically differs.

In the past, too, research has shown cannabis use to be beneficial for women on different counts. A 2020 study, for instance, linked “routine cannabis consumption” among females improved their sexual satisfaction — positively impacting levels of desire, arousal, and even orgasms.

Another study from 2002 suggests cannabis use could be helpful for women going through menopause — especially if they are experiencing hot flashes, which is the most common of menopause symptoms. By lowering one’s body temperature, THC, a component of cannabis, may help mitigate the hot flashes.

A review of historical records even indicates the ability of cannabis to relieve pain, stabilize mood, prevent nausea, or help ease PMS.

However, in order to see whether the association between cannabis use and lowered risk of diabetes throws up any viable treatment options, there’s still a lot to be done. First of which, of course, is that scientists would have to understand the exact bodily mechanism behind the association.

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