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Meds 700 Medicinal Uses for Cannabis sorted by Disease

Pages 501 - 505

Initial study of Hemp seeds protein on antifatigue and the immunomodulation effects in mice (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/18589601

Hemp: A replacement for common food allergens? (news - 2009)

http://www.examiner.com/x-20151-Manchester-Gluten-Free-Examiner~y2009m8d25-Hemp--A- replacement-for-common-food-allergens

Curb Cravings With Hemp Seeds (news - 2009)

http://pr.cannazine.co.uk/200909231206/green/eco-news/curb-cravings-with-hemp-seeds.html

The cardiac and haemostatic effects of dietary hempseed. (full - 2010)

http://www.nutritionandmetabolism.com/content/pdf/1743-7075-7-32.pdf

Influence of Feed Supplementation with Cannabis Sativa on Quality of Broilers Carcass (full - 2010) http://www.pvj.com.pk/pdf-files/30_1/34-38.pdf

Information on Chia, Hemp & Flax (article – 2010)

http://www.ehow.com/facts_7460031_information-chia_-hemp-flax.html

Dietary intakes in a group of marihuana smoking patients (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20694309

Evaluating the Quality of Protein from Hemp Seed (Cannabis sativa L.) Products Through the use of the Protein Digestibility-Corrected Amino Acid Score Method (abst - 2010) http://pubs.acs.org/doi/abs/10.1021/jf102636b

The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21331775

Hemp Seeds are Full of Health (news - 2010)

http://www.naturalnews.com/029729_hemp_seeds_health.html

Efficacy of a Chinese herbal proprietary medicine (Hemp Seed Pill) for functional constipation. (full – 2011) http://www.nature.com/ajg/journal/v106/n1/pdf/ajg2010305a.pdf

The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21893466

Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21294251

Proteomic profiling of hempseed proteins from Cheungsam. (abst - 2012)

http://www.ncbi.nlm.nih.gov/pubmed/22040604
501

NUTRITION – HEMP SEED OIL


King‘s College Review of Nutritional Attributes of Cold Pressed Hemp Seed Oil (full – no date) http://www.goodwebsite.co.uk/kingsreport.pdf

Hemp Foods & Oils Primer (article - no date)

http://manitobaharvest.com/articles_studies/3803/Hemp-Foods-&-Oils-Primer.html

Hemp Oil vs Flax Oil. Which One is Right for Me? (article - no date)

http://manitobaharvest.com/articles_studies/3794/Hemp-Oil-vs-Flax-Oil.-Which-One-is-Right-for- Me%3F.html

Hemp Powder Vs. Hemp Oil (article – no date)

http://www.ehow.com/facts_5918149_hemp-powder-vs_-hemp-oil.html

Hemp & GLA: Good Fat Burns Bad Fat (article - no date)

http://manitobaharvest.com/articles_studies/3813/Hemp-&-GLA:-Good-Fat-Burns-Bad- Fat-.html

Uses for Hemp Oil (article – no date)

http://www.ehow.com/about_5340254_uses-hemp-oil.html

Hemp Seed Oil - Your source for essential fat (article - no date)

http://manitobaharvest.com/articles_studies/3810/Hemp-Seed-Oil---Your-source-for-essential-fat.html

Hemp: The Right Choice for Omega-6 (article - no date)

http://manitobaharvest.com/articles_studies/3814/Hemp:-The-Right-Choice-for-Omega-6-.html

Hemp Oil Vs. Flax Oil (article – no date)

http://www.ehow.com/facts_5949889_hemp-oil-vs_-flax-oil.html

Cannabis Sativa Seed Pressings (ad - no date) http://www.med-marijuana.com/index.htm

Therapeutic Hemp Oil (news - 1993) http://www.ukcia.org/research/TherapeuticHempOil.php

Hemp seed oil: A source of valuable essential fatty acids (full - 1996)

http://www.hempfood.com/IHA/iha03101.html

Occurrence of "omega-3" stearidonic acid in hemp seed (full - 1996)

http://www.hempfood.com/IHA/iha03208.html

Hemp Seed Oil : The Wonder Oil For the New Millennium (full - 1999)

http://www.ukcia.org/research/Happi/HempSeedOilTheWonderOilForTheNewMillennium.htm

Hemp and Health (book excerpt - 1999)

http://www.rexresearch.com/hhusb/hmphlth.htm#hhl4
502

Consumption and quantitation of delta9-tetrahydrocannabinol in commercially available hemp seed oil products. (abst – 2000) http://www.ncbi.nlm.nih.gov/pubmed/11043660

Hemp Supplement Boosts Body AND Mind (anecdotal/news - 2001)

http://pr.cannazine.co.uk/201006011282/green/eco-news/hemp-supplement-boosts-body-and-mind.html

Characteristics of hemp (Cannabis sativa L.) seed oil (abst - 2002)

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6R-44KW0MJ- 6&_user=10&_coverDate=01%2F31%2F2002&_alid=1224442428&_rdoc=729&_fmt=high&_orig=searc h&_cdi=5037&_sort=r&_st=13&_docanchor=&view=c&_ct=14348&_acct=C000050221&_version=1&_ urlVersion=0&_userid=10&md5=39826d98860a306a6242e1b6f6d60bd7

Nutritional Profile and Benefits of Hemp Seed, Nut, and Oil (full - 2003)

http://www.drbronner.com/pdf/hempnutrition.pdf

Hemp-seed and olive oils: their stability against oxidation and use in O/W emulsions. (abst – 2004) http://www.ncbi.nlm.nih.gov/pubmed/16130045

Hemp Oil (full - 2005) http://www.innvista.com/health/foods/hemp/hempoil.htm Efficacy of dietary hempseed oil in patients with atopic dermatitis. (abst - 2005)

http://www.ncbi.nlm.nih.gov/pubmed/16019622

Study on the extraction process for cannabinoids in hemp seed oil by orthogonal design (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/16131037

Hemp-seed and olive oils: their stability against oxidation and use in O/W emulsions. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/16130045

How Hemp Seed Oil Can Help Your Arthritis (news – 2009)

http://www.thefreelibrary.com/How+Hemp+Seed+Oil+Can+Help+Your+Arthritis-a01074002477

Hemp Oil Compared to Flax Oil (article – 2010)

http://www.ehow.com/facts_7639247_hemp-oil-compared-flax-oil.html

Hemp Seed Oil for Skin (news – 2010)

http://www.livestrong.com/article/340189-hemp-seed-oil-for-skin/

Vets use hemp seed oil on animals with cancer (news - 2010)

http://www.examiner.com/x-33448-LA-County-Environmental-News-Examiner~y2010m3d22-Vets-use- hemp-seed-oil-on-animals-with-cancer

Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. (abst – 2011) http://www.nature.com/neuro/journal/v14/n3/full/nn.2736.html

Anchovy red wine vinegarette with or without cannabis oil (news – 2011)

http://www.examiner.com/chef-about-town-in-seattle/recipes-that-make-lives-easier-anchovy-red-wine- vinegarette-with-or-wi
503

Hemp Oil Vs. Flax Oil (news – 2011)

http://www.livestrong.com/article/413750-hemp-oil-vs-flax-oil/

What Are the Benefits of Hemp Seed Oil? (news – 2011)

http://www.ehow.com/facts_5796438_benefits-hemp-seed-oil_.html

O-1602 – synthetic Cannabidiol analog, GPR – 55 agonist
A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement

in rodents. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355

The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21683763

A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355

The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21744421

A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21885477

The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21981246

0-1966 - a synthetic, CB2 agonist

Acute effects of a selective cannabinoid-2 receptor agonist on neuroinflammation in a murine model of traumatic brain injury (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21332427/abstract/Acute_effects_of_a_selective_c annabinoid_2_receptor_agonist_on_neuroinflammation_in_a_murine_model_of_traumatic_brain_injury_

Modulation of inflammatory responses by a cannabinoid-2-selective agonist after spinal cord injury. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21970496
504

OBESITY

Hemp & GLA: Good Fat Burns Bad Fat (article - no date)

http://manitobaharvest.com/articles_studies/3813/Hemp-&-GLA:-Good-Fat-Burns-Bad- Fat-.html

Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory. (abst - 1988) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=117

Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice. (abst – 2000) http://www.ncbi.nlm.nih.gov/pubmed/10762668

Dietary intake and nutritional status of US adult marijuana users: results from the Third National Health and Nutrition Examination Survey. (full – 2001) http://journals.cambridge.org/action/displayFulltext?type=6&fid=626876&jid=PHN&volumeId=4&issueId =03&aid=562676&bodyId=&membershipNumber=&societyETOCSession=&fulltextType=RA&fileId=S1 368980001000738

Marijuana "Munchies" May Hold a Key to Obesity (news - 2001)

http://www.webmd.com/news/20010411/marijuana-munchies-may-hold-key-to-obesity

The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166293/

Endocannabinoids and the regulation of body fat: the smoke is clearing (full - 2003)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166302/?tool=pmcentrez

Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain. (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/12914975

CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity (full - 2004) http://www.nature.com/ijo/journal/v28/n4/full/0802583a.html

Activation of the Peripheral Endocannabinoid System in Human Obesity (full - 2005)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228268/?tool=pmcentrez

Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity (full - 2005) http://www.jci.org/articles/view/23057/version/1

Food for thought: endocannabinoid modulation of lipogenesis (full - 2005)

http://www.jci.org/articles/view/25076/version/1
505
 
Pages 506 - 510

Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood. (full - 2005) http://ebm.rsmjournals.com/cgi/content/full/230/4/225

Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087161/?tool=pmcentrez

Endocannabinoids in the Regulation of Appetite and Body Weight. (abst - 2005)

http://medical-journals.healia.com/doc/16148436/Endocannabinoids-in-the-regulation-of-appetite-and- body-weight

Dysregulation of the Peripheral and Adipose Tissue Endocannabinoid System in Human Abdominal Obesity (full – 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228260/?tool=pmcentrez

Regulation, Function, and Dysregulation of Endocannabinoids in Models of Adipose and ß-Pancreatic Cells and in Obesity and Hyperglycemia (full - 2006) http://jcem.endojournals.org/cgi/content/full/91/8/3171?ijkey=83a68cef202eafe129332eda53eee8eb613499 82

Does Cannabis Hold the Key to Treating Cardiometabolic Disease (full - 2006)

http://www.nature.com/nrcardio/journal/v3/n3/full/ncpcardio0504.html

AM 251 produces sustained reductions in food intake and body weight that are resistant to tolerance and conditioned taste aversion (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615836/?tool=pmcentrez

Weight Control in Individuals With Diabetes (full - 2006)

http://care.diabetesjournals.org/content/29/12/2749.full?maxtoshow=&hits=80&RESULTFORMAT=&full text=cannabis&searchid=1&FIRSTINDEX=2000&resourcetype=HWCIT

The emerging role of the endocannabinoid system in endocrine regulation and energy balance. (full - 2006) http://edrv.endojournals.org/cgi/content/full/27/1/73

Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2- arachidonoylglycerol. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16949718

Identification of Endocannabinoids and Related Compounds in Human Fat Cells (full - 2007) http://www.nature.com/oby/journal/v15/n4/full/oby2007100a.html

The endogenous cannabinoid system: a new player in the brain-gut-adipose axis (full - 2007) http://www.cannabis-med.org/english/journal/en_2007_02_1.pdf

GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes

and obesity (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268073/?tool=pmcentrez
506

Activating Parabrachial Cannabinoid CB1 Receptors Selectively Stimulates Feeding of Palatable Foods in Rats (full - 2008) http://www.jneurosci.org/cgi/content/full/28/39/9702?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full – 2008) http://gut.bmj.com/content/57/8/1140.full

Endocannabinoids and the Control of Energy Homeostasis (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586261/?tool=pmcentrez

The Role of Adipocyte Insulin Resistance in the Pathogenesis of Obesity-Related Elevations in Endocannabinoids (full – 2008) http://diabetes.diabetesjournals.org/content/57/5/1262.full?sid=00769f3d-54ab-451b-b69e-4650931c5e25

Genetic Variations at the Endocannabinoid Type 1 Receptor Gene (CNR1) Are Associated with Obesity Phenotypes in Men (full - 2008) http://jcem.endojournals.org/cgi/content/full/92/6/2382

Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet. (full - 2008) http://www.nature.com/oby/journal/v16/n3/full/oby2007106a.html

The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet. (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275439/?tool=pubmed

Endocannabinoids and the Control of Energy Homeostasis (full – 2008)

http://www.jbc.org/content/283/48/33021.full?sid=931583b1-e797-43e0-8296-7fd75bb49403

ENDOCANNABINOIDS AND THE NEUROCHEMISTRY OF GLUTTONY. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18638022

Dysregulation of the endocannabinoid system in obesity. (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18426509

Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseed- enriched diet. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18418423

Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697695/?tool=pubmed

Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and

energy processing induced by food deprivation and re-feeding. (full – 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757684/?tool=pubmed
507

Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688760/?tool=pubmed

Biomarkers of Endocannabinoid System Activation in Severe Obesity (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808340/?tool=pubmed

The endocanabinnoid system and diabetes - critical analyses of studies conducted with rimonabant (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770455/?tool=pmcentrez

Cannabinoids for clinicians: the rise and fall of the cannabinoid antagonists (full - 2009)

http://www.eje- online.org/cgi/content/full/161/5/655?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid &searchid=1&FIRSTINDEX=160&resourcetype=HWCIT

Endocannabinoids and Their Receptors as Targets for Obesity Therapy (full - 2009)

http://endo.endojournals.org/cgi/content/full/150/6/2531#top

Cannabinoids for clinicians: the rise and fall of the cannabinoid antagonists (full - 2009)

http://www.eje- online.org/cgi/content/full/161/5/655?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid &searchid=1&FIRSTINDEX=160&resourcetype=HWCIT

Endocannabinoids and cardiovascular prevention: real progress? (abst - 2009)
http://www.pagepress.org/journals/index.php/hi/article/view/1162[/FONT]

Anti-inflammatory effect of palmitoylethanolamide on human adipocytes.

http://www.ncbi.nlm.nih.gov/pubmed/19131941

Endogenous cannabinoid signalling and energy balance (abst – 2009)

http://gradworks.umi.com/NR/44/NR44386.html

Natural Pot-Like Compound Could Fight Obesity (news - 2009)

(abst – 2009)
http://www.scientificamerican.com/p...=natural-pot-like-compound-could-fig-09-12-29

Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. (full – 2010) http://www.jneurosci.org/content/30/18/6273.long

Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients (full - 2010) http://www.lipidworld.com/content/9/1/43

Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype (full – 2010) http://ajpgi.physiology.org/content/299/1/G63.full?sid=fc6948f0-78cf-405c-981b-afaa05ee417c

The endocannabinoid system links gut microbiota to adipogenesis (full - 2010)

http://www.nature.com/msb/journal/v6/n1/full/msb201046.html
508

The Effects of Rimonabant on Brown Adipose Tissue in Rat: Implications for Energy Expenditure (full - 2010) http://www.nature.com/oby/journal/v17/n2/full/oby2008509a.html

Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways. (full – 2010) http://diabetes.diabetesjournals.org/content/59/11/2826.long#sec-25

A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055343/?tool=pubmed

Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes? (full – 2010) http://www.jci.org/articles/view/44...ext]=&search[article_text]=cannabinoid&search[a uthors_text]=&search[fpage]=&search[title_text]=&search[volume]=

Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis (abst - 2010) http://www.nature.com/npp/journal/vaop/ncurrent/abs/npp201058a.html

Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age. (abst – 2010) http://www.springerlink.com/content/g037q1lh40l15161/

Modulation of Adipocyte Biology by Δ9-Tetrahydrocannabinol (abst - 2010)

http://www.nature.com/oby/journal/vaop/ncurrent/abs/oby2010100a.html

Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20013888

Cannabis Use and Obesity and Young Adults ( abst - 2010)

http://informahealthcare.com/doi/abs/10.3109/00952990.2010.500438

Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048484/?tool=pubmed

Sweet taste and (AAT)12 repeat in the cannabinoid receptor gene in obese females (letter – 2011) http://www.jstage.jst.go.jp/article/endocrj/58/4/323/_pdf

Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/20965292

The neutral cannabinoid CB1 receptor antagonist AM4113 regulates body weight through

changes in energy intake in the rat. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21056053
509

The role of central CB2 cannabinoid receptors on food intake in neonatal chicks. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21927979

Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors. (abst - 2011) http://marijuana.researchtoday.net/archive/8/1/3517.htm

Obesity and Cannabis Use: Results From 2 Representative National Surveys
(abst – 2011) http://aje.oxfordjournals.org/conte....kwr200.abstract?sid=18de840f-92a2-40d2-b154- 2e236ba97020

Frequency Of Marijuana Use Associated With Lower Prevalence Of Obesity, Study Says (news – 2011) http://www.norml.org/index.cfm?Group_ID=8670

Smoking marijuana not linked to obesity: study (news – 2011)

http://health.yahoo.net/news/s/nm/us_marijuana_obesity

Dietary conditions and highly palatable food access alter rat cannabinoid receptor expression and binding density. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22005165

The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21981246

OBSESSIVE COMPULSIVE DISORDER

Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. (full – 2007) http://www.nature.com/npp/journal/v32/n5/pdf/1301224a.pdf

Improvement in Refractory Obsessive Compulsive Disorder With Dronabinol (letter - 2008) http://ajp.psychiatryonline.org/cgi/content/full/165/4/536

Science: THC effective in obsessive compulsive disorder according to case reports (news - 2008) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=268#2

Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20695034

Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive- compulsive behaviour. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21796370
510
 
Pages 511 - 515

Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21145341/abstract/Inhibition_of_endocannabinoid _catabolic_enzymes_elicits_anxiolytic_like_effects_in_the_marble_burying_assay_

OMEGA-3/ CB1 CONNECTION (without Omega 3, new CB1 receptors are made imperfectly) also see NUTRITION – HEMP SEED OIL, CBR- CB1 receptors

Hemp Packs in Powerful Source of Preconception Nutrition (article - no date)

http://manitobaharvest.com/articles_studies/3812/Hemp-Packs-in-Powerful-Source-of-Preconception- Nutrition.html

Omega-3 and Omega-6 Essential fatty Acids (EFA) (infomercial/ad – no date)

http://www.advance-health.com/efa.html

Occurrence of "omega-3" stearidonic acid in hemp seed (full - 1996)

http://www.hempfood.com/IHA/iha03208.html

Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/12678501

Oily fish makes 'babies brainier' (news - 2006) (hemp seed- at the end)

http://news.bbc.co.uk/2/hi/health/4631006.stm

Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20013888

Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed

Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. (abst – 2011) http://www.nature.com/neuro/journal/v14/n3/full/nn.2736.html

Fish oil promotes survival and protects against cognitive decline in severely undernourished mice by normalizing satiety signals. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21109417

Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in
different human prostate and breast cancer cell lines. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21995886
511

Omega-3 PUFA Deficiency Abolishes Endocannabinoid-Linked Neuronal Functions (news - 2011) http://www.fatsoflife.com/article.php?nid=1&edition=this&id=1837&issueid=85

Omega-3 deficiency disrupts cannibinoid receptor function in brain (news – 2011)

http://www.wellsphere.com/general-medicine-article/omega-3-deficiency-disrupts-cannibinoid-receptor- function-in-brain/1347465

A Brain Wrought Without Omega-3 (news – 2011)

http://www.schizophreniaforum.org/new/detail.asp?id=1646

Poor Diet Impairs Cannabinoid Receptors (news – 2011)

http://www.freedomisgreen.com/poor-diet-impairs-cannabinoid-receptors/

Cannabinoid Receptor Function is Altered by Nutrionally Deficient Diet

(news – 2012)
http://www.examiner.com/medical-mar.../cannabinoid-receptor-function-is-altered-by- nutrionally-deficient-diet

ORGAN TRANSPLANTS

Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient. (full - 1988) http://chestjournal.chestpubs.org/content/94/2/432.long

Successfully treated invasive pulmonary aspergillosis associated with smoking marijuana in a renal transplant recipient. (abst - 1996) http://www.ncbi.nlm.nih.gov/pubmed/8685958

Exogenous lipid pneumonia related to smoking weed oil following cadaveric renal transplantation (abst, click for full- 2000) http://www.ncbi.nlm.nih.gov/sites/pubmed

Marinol Death Sentence: Oregon Man Denied Liver Transplant Because of Prescription - - He's Not the Only One (news – 2003) http://stopthedrugwar.org/chronicle-old/299/notransplant.shtml

Endocannabinoids and cannabinoid receptors in ischaemia–reperfusion injury and preconditioning (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219536/?tool=pmcentrez

The debate about marijuana usage in transplant candidates: recent medical evidence on marijuana health effects. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18685302

Medical Marijuana Users Denied Organ Transplants (news – 2008)

http://blogs.wsj.com/health/2008/05/19/medical-marijuana-users-denied-organ-transplants/

Is medical-marijuana use reason to deny someone an organ transplant? (news – 2008)

http://seattletimes.nwsource.com/html/health/2004389825_liver03m.html
512

Should Hepatitis C Patients Who Smoke Marijuana Be Eligible For Liver Transplants? (news - 2008) http://www.sciencedaily.com/releases/2008/10/081022211032.htm

Marijuana Use in Potential Liver Transplant Candidates. (abst - 2009)

http://www.unboundmedicine.com/medline/ebm/record/19067667/abstract/Marijuana_Use_in_Potential_Li ver_Transplant_Candidates_

Woman Dies After Being Denied Organ Transplant (news – 2009)

http://ssdp.org/news/blog/woman-dies-after-being-denied-organ-transplant

Do cannabinoids have a therapeutic role in transplantation (full – 2010)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923447/?tool=pubmed

Denial of hepatic transplantation on the basis of smoking: is it ethical? (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20154621

Oregon hospitals denying life saving organ transplants to legal medical marijuana patients (news - 2010) http://www.huffingtonpost.com/russ-belville/oregon-hospitals-denying_b_575965.html

Health Tragedy: Patients Denied Life-Saving Transplants for Their "Abuse of Illicit Substances" (news – 2010) http://www.alternet.org/health/145432/health_tragedy:_patients_denied_life- saving_transplants_for_their_%22abuse_of_illicit_substances%22

Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: Evidence from an experimental murine model. (full – 2011) http://jpet.aspetjournals.org/content/early/2011/06/14/jpet.111.182717.long

Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21063029

Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21063029

The Denial of Organ Transplants to Medical Marijuana Patients (news – 2011)

http://www.huffingtonpost.com/russ-belville/the-denial-of-organ-trans_b_435348.html

Cancer Patient Taken Off Of Liver Transplant List Because Of Medical Marijuana Use (news – 2011) http://americansforsafeaccess.org/article.php?id=6986

Cedars-Sinai Denying Transplant To Medical Marijuana Patient With Inoperable Liver Cancer (news – 2011) http://www.cannabisculture.com/v2/content/2011/11/17/Cedars-Sinai-Denying-Transplant-Medical- Marijuana-Patient-Inoperable-Liver-Cancer
513

OSTEOPOROSIS/ BONE
S

Cannabinoid receptor type 2 gene is associated with human osteoporosis (full - 2005)

http://hmg.oxfordjournals.org/cgi/content/full/14/22/3389?maxtoshow=&hits=80&RESULTFORMAT=&f ulltext=cannabinoid&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT

Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1430341/?tool=pmcentrez

Peripheral cannabinoid receptor, CB2, regulates bone mass (full - 2006)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1334629/?tool=pmcentrez

Involvement of Neuronal Cannabinoid Receptor CB1 in Regulation of Bone Mass and Bone Remodeling (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238031/?tool=pmcentrez

Researchers from the Hebrew University Discover New Drug for Osteoporosis (news – 2006) http://news.softpedia.com/news/Researchers-From-the-Hebrew-University-Discover-New-Drug-for- Osteoporosis-15808.shtml

New hope for osteoporosis sufferers (news - 2006)

http://www.news-medical.net/news/2006/01/04/15164.aspx

Prototype drug to prevent osteoporosis based on cannabinoids found in the body (news - 2006) http://www.news-medical.net/?id=15220

Hebrew U. Researchers Find Cannabis Can Strengthen Bones (news - 2006)

http://www.israelnationalnews.com/News/News.aspx/96146

Scientists Develop Prototype Drug To Prevent Osteoporosis Based On Cannabinoids Produced By Body (news - 2006) http://www.sciencedaily.com/releases/2006/01/060104232013.htm

New Weapon In Battle Against Osteoporosis (news - 2006)

http://www.medicalnewstoday.com/articles/35621.php

Activation of CB2 receptor attenuates bone loss in osteoporosis (news - 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=210#2

Cannabis-like compound prevents bone loss (news - 2006)

http://www.thehempire.com/index.php/cannabis/news/cannabis_like_compound_prevents_bone_loss

Regulation of skeletal remodeling by the endocannabinoid system. (abst - 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17646266
514

Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/17205329

Cannabinoid receptors and the regulation of bone mass (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219540/?tool=pmcentrez

Regulation of Bone Mass, Osteoclast Function, and Ovariectomy-Induced Bone Loss by the Type 2 Cannabinoid Receptor (full - 2008) http://endo.endojournals.org/cgi/content/full/149/11/5619?maxtoshow=&hits=80&RESULTFORMAT=&f ulltext=cannabinoid&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT

The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling. (full - 2008) http://www.fasebj.org/cgi/content/full/22/1/285

Role of cannabinoid receptors in bone disorders: alternatives for treatment
(abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/19221634?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa nel.Pubmed_RVDocSum&ordinalpos=52

Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/17786950

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737440/?tool=pubmed

The influence of cannabinoid CB2 receptor in adult rat mesenchymal stem cell viability (abst – 2009) http://www.physoc.org/custom2/publications/proceedings/archive/article.asp?ID=Proc Physiol Soc %2015PC171

Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro- inflammatory cytokines during experimental periodontitis in rats. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19070683

Cannabinoids and the skeleton: From marijuana to reversal of bone loss. (abst - 2009)

http://www.unboundmedicine.com/medline/ebm/record/19634029/abstract/Cannabinoids_and_the_skeleto n:_From_marijuana_to_reversal_of_bone_loss_

Activation of CB2 cannabinoid receptors: a novel therapeutic strategy to accelerate osseointegration of dental implants. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19027245

Marijuana/Cannabis may protect against osteoporosis (news - 2009)

http://www.news-medical.net/news/20090813/MarijuanaCannabis-may-protect-against-osteoporosis.aspx

Cannabis may prevent osteoporosis (news - 2009)

http://news.bbc.co.uk/2/hi/uk_news/scotland/edinburgh_and_east/8199007.stm
515
 
Pages 516 - 520

Hypothalamic regulation of bone. (full – 2010)

http://jme.endocrinology-journals.org/cgi/content/full/45/4/175

Cannabinoid Receptors as Target for Treatment of Osteoporosis: A Tale of Two Therapies (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001217/?tool=pubmed

Tissue Engineering of Cartilage; Can Cannabinoids Help? (full – 2010)

http://www.mdpi.com/1424-8247/3/9/2970/pdf

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20176037

Cannabinoids and Bone: Friend or Foe? (abst - 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20532878

The endocannabinoid signaling system: a marriage of PUFA and musculoskeletal health. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20934863

Control of bone remodeling by nervous system. Nervous system and bone (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/21123931

Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20826813

The Type 2 Cannabinoid Receptor Regulates Bone Mass and Ovariectomy-Induced Bone Loss by Affecting Osteoblast Differentiation and Bone Formation (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21447627/abstract/The_Type_2_Cannabinoid_Rec eptor_Regulates_Bone_Mass_and_Ovariectomy_Induced_Bone_Loss_by_Affecting_Osteoblast_Differenti ation_and_Bone_Formation_

The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21237298

The role of cannabinoid receptors in bone remodeling in a CB1/2 double knockout mouse (abst – 2011) http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/492.5?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&sortspec=date&resourcety pe=HWCIT

CANNABINOIDS AND BONE: ENDOCANNABINOIDS MODULATE HUMAN OSTEOCLAST FUNCTION IN VITRO. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21649637

Skeletal lipidomics: regulation of bone metabolism by fatty acid amide family. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21557736
516

OVERDOSES


Cannabis Indica Poisoning (1899) http://www.onlinepot.org/medical/Dr_Tods_PDFs/s2_2.pdf Two cases of Poisoning by Cannabis Indica (1900)

http://www.onlinepot.org/medical/Dr_Tods_PDFs/s2_3.pdf

Collapse after intravenous injection of hashish. (full - 1968)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1986226/?tool=pmcentrez&page=1

Inadvertent ingestion of marijuana - Los Angeles, California, 2009 (full - 2009)

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5834a2.htm

Accidental cannabis poisoning in children: experience of the Marseille poison center (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19541448

Information for Health Care Professionals (revised) - Overdose/Toxicity (Health Canada) (full - 2010) http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/index-eng.php#a9_0

Accidental cannabis poisoning in children: report of four cases in a tertiary care center from southern Spain (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21283933/abstract/[Accidental_cannabis_pois oning_in_children:_report_of_four_cases_in_a_tertiary_care_center_from_southern_Spain%5D_

Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/20634020/abstract/Prolonged_coma_in_a_child_d ue_to_hashish_ingestion_with_quantitation_of_THC_metabolites_in_urine_

OVERVIEWS

On Being Stoned: A Psychological Study of Marijuana Intoxication (book - 1971) http://www.druglibrary.org/special/tart/tartcont.htm

(full - 1982) Delirium following ingestion of marijuana present in chocolate cookies


Accidental Overdose Intoxication: A Hazard of Drug Smuggling

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2552908/?tool=pmcentrez&page=1
(full - 2006) http://www.cnsspectrums.com/aspx/articledetail.aspx?articleid=357
517

Ganja in Jamaica (book – 1976) http://www.cifas.us/cannabis/PDFs/OCRGanjainJamaica.pdf Marijuana Grower's Handbook (text - 1990) http://www.lycaeum.org/~sky/data/mjgrowers.html

HEMP, THE PLANT THAT CAN SAVE MOTHER EARTH (transcript – 1990)

http://www.ratical.org/renewables/hempHDRT.html#entry
The Emperor Wears No Clothes (book - 2007) http://www.jackherer.com/thebook/

Cannabis; extracting the medicine (book – 2007)

http://mcforadhd.free.fr/Hazekamp EXTRACTING THE MEDICINE.pdf

Cannabinoids: A New Group of Agonists of PPARs (full – 2007)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2220031/?tool=pubmed

Cannabis and Endocannabinoids: The Old Man and the Teenagers (full – 2007)

http://onlinelibrary.wiley.com/doi/10.1002/cbdv.200790143/pdf

Pharmacological actions and therapeutic uses of cannabis and cannabinoids (full – 2008)
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.2001.02269.x/full

Medicinal Use of Cannabis in the United States: Historical Prespectives, Current Trends and future Directions (full - 2009)

http://www.letfreedomgrow.com/cmu/JOM_5-3-03-Carter.pdf
Hemp Industry Association - Facts (article - 2009) http://www.thehia.org/facts.html

Information for Health Care Professionals- Marihuana (marijuana, cannabis) dried plant for administration by ingestion or other means (Health Canada) (full – 2010) http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/index-eng.php

Cannabis and Its Derivatives: Review of Medical Use (full – 2011)

http://www.jabfm.org/cgi/content/full/24/4/452

Global Commission Drug Report (links to full in various languages – 2011)

http://www.globalcommissionondrugs.org/Report

Scientific Opinion on the safety of hemp (Cannabis genus) for use as animal feed (full – 2011) (deceptive title) http://www.hanf-info.ch/info/en/IMG/pdf/EIHA-11-05-31_EIHA-Statement_on_THC_in_feed.pdf

Introduction to the Endocannabinoid System (news – 2011)

http://norml.org/index.cfm?Group_ID=8444

Is Pot Good For You? (news – 2011)

http://www.time.com/time/magazine/article/0,9171,1003570,00.html
518

PAIN


ANTI-EDEMA AND ANALGESIC PROPERTIES OF Δ9- TETRAHYDROCANNABINOL (THC) (abst- 1973) http://jpet.aspetjournals.org/content/186/3/646.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=marihuana&searchid=1&FIRSTINDEX=2160&resourcetype=HWCIT

Analgesic effect of delta-9-tetrahydrocannabinol. (abst - 1975)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=16

The analgesic properties of delta-9-tetrahydrocannabinol and codeine. (abst - 1975)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=17

Marihuana as a therapeutic agent for muscle spasm or spasticity. (abst - 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=53

ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L. (full - 1988) http://www.ukcia.org/research/AnalgesicAndAntiInflammatoryActivityofConstituents.html

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients. (abst - 1996) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=12

The perceived effects of smoked cannabis on patients with multiple sclerosis. (abst - 1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=13

Pain relief with oral cannabinoids in familial Mediterranean fever (abst - 1997)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=18

Hypoactivity of the Spinal Cannabinoid System Results in NMDA-Dependent Hyperalgesia (full – 1998) http://www.jneurosci.org/content/18/1/451.long

Doped skin (news - 1998)

http://www.newscientist.com/article/mg15921434.700-doped-skin.html

Pain modulation by release of the endogenous cannabinoid anandamide (full - 1999)

http://www.pnas.org/content/96/21/12198.full

Analgesic effect of the cannabinoid analogue nabilone is not mediated by opioid receptors. (abst - 1999) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=203

Brain Releases Marijuana-Like Substance In Response To Pain, Study Finds (news - 1999) http://www.sciencedaily.com/releases/1999/10/991013074947.htm
519

Most pain patients gain benefit from cannabis in a British study (news - 2000)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=84#1

Therapeutic aspects of cannabis and cannabinoids. (full - 2001)

http://bjp.rcpsych.org/cgi/content/full/178/2/107

Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review (full - 2001) http://www.ukcia.org/research/EffectiveTreatmentOptionForPain.pdf

Therapeutic Aspects of Cannabis and Cannabinoids (full - 2001)

http://bjp.rcpsych.org/cgi/reprint/178/2/107.pdf

Tetrahydrocannabinol for treatment of chronic pain (abst - 2001)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=147

The Role of Cannabis and Cannabinoids in Pain Management (full – 2002)

http://www.humanhemphealth.ca/Russo-AAPM_chapter.pdf

A Dramatic Response to Inhaled Cannabis in a Woman with Central Thalamic Pain and Dystonia (full - 2002) http://www.jpsmjournal.com/article/PIIS0885392402004268/fulltext

CB2 cannabinoid receptor agonists: pain relief without psychoactive effects? (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12550743

The Pharmacology of Cannabinoid Derivatives: Are There Applications to Treatment of Pain? (abst – 2002) http://medical-journals.healia.com/...acology-of-cannabinoid-derivatives-are-there- applications-to-treatment-of-pain

A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms (full - 2003) http://www.ukcia.org/research/WholePlantExtractsImproveNeurogenicSymptoms.pdf

Cannabis reduces opioid dose in the treatment of chronic non-cancer pain.

http://www.jpsmjournal.com/article/S0885-3924(03)00142-8/fulltext

Cannabis and Pain Management (article - 2003)

http://www.letfreedomgrow.com/articles/can030828.htm

(full - 2003)

Topical cannabinoid enhances topical morphine antinociception. (abst - 2003)

http://www.ncbi.nlm.nih.gov/pubmed/14499448

Cannabis use for chronic non-cancer pain: results of a prospective survey. (abst - 2003)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=91
520
 
Pages 521 - 525

Safety and efficacy of dronabinol in the treatment of agitation in patients with Alzheimer‘s disease with anorexia: A retrospective chart review (abst - 2003) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=61

Cannabis Use in HIV for Pain and Other Medical Symptoms (full - 2004)

http://www.jpsmjournal.com/article/S0885-3924(05)00063-1/fulltext

Are oral cannabinoids safe and effective in refractory neuropathic pain?
(abst - 2004) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=143

Ajulemic acid: A novel cannabinoid produces analgesia without a ―high‖ (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15240185

Cannabinoids called equivalent to codeine for killing pain (news - 2004)

http://findarticles.com/p/articles/mi_hb4365/is_13_37/ai_n29110217/?tag=content;col1

High hopes for cannabinoid analgesia (news - 2004)

http://www.bmj.com/cgi/content/full/329/7460/257?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabis&searchid=1&FIRSTINDEX=2880&resourcetype=HWCIT

Chronic Pain and Cannabinoids (full – 2005)

http://www.drkoprp.com/pdfs/fibromyalgia/CannabinoidsPPM.pdf

CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids (full - 2005) http://www.pnas.org/content/102/8/3093.full

Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751505/?tool=pubmed

Analgesia through endogenous cannabinoids (analysis - 2005)

http://www.cmaj.ca/cgi/content/full/173/4/357?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=end ocannabinoid&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=date&resourcetype=HW CIT

Enhancement of transdermal fentanyl and buprenorphine antinociception by transdermal delta9-tetrahydrocannabinol. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16288738

Cannabis: Use in HIV for Pain and Other Medical Symptoms (abst - 2005)

http://www.ncbi.nlm.nih.gov/pubmed/15857739

Body's Pot-Like Chemicals May Help Curb Pain (news - 2005)

http://www.webmd.com/pain-management/news/20050622/bodys-pot-like-chemicals-may-help-curb-pain

A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain management. (full - 2006) http://journals.lww.com/anesthesiology/Fulltext/2006/05000/A_Multicenter_Dose_escalation_Study_of_th e.21.aspx
521

Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751298/?tool=pmcentrez

Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes (full - 2006) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2430692&tool=pmcentrez

The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=177

Role of cannabinoid receptor agonists in mechanisms of suppression of central pain syndrome. (abst - 2006) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=17369898&dopt=abstrac tplus

Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : A double-blind placebo-controlled cross-over trial.
(abst - 2006)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=200

Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16834825

Benefits of an add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain - a randomized controlled trial. (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=197

Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine. (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=178

Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16480822

Cannabinoid analgesia as a potential new therapeutic option in the treatment of chronic pain. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16449552

Cannabinoids Enhance Analgesic Effects Of Anti-Inflammatory Drugs, Study Says (news - 2006) http://www.norml.org/index.cfm?Group_ID=6819

In MedPanel Summit, Leading Pain Experts Name Cannabinoids Among Most Promising Approaches to Treating Neuropathic Pain, Assert That Sociopolitical Climate Will Hamper Drug Approvals (news - 2006)

http://www.redorbit.com/news/health/545812/in_medpanel_summit_leading_pain_experts_name_cannabin oids_among_most/index.html?source=r_health
522

Cannabis effective at relieving pain after major surgery (news - 2006)

http://www.news-medical.net/?id=17995

Cross-sensitization and cross-tolerance between exogenous cannabinoid antinociception and endocannabinoid-mediated stress-induced analgesia (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771679/?tool=pubmed

Low dose combination of morphine and Δ9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040345/

Antinociceptive Synergy Between the Cannabinoid Receptor Agonist WIN 55,212-2 and Bupivacaine in the Rat Formalin Test (full - 2007)
http://www.anesthesia- analgesia.org/content/104/3/719.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid& searchid=1&FIRSTINDEX=320&resourcetype=HWCIT

Dose-dependent effects of smoked cannabis on capsaicin-induced pain and hyperalgesia in healthy volunteers. (full - 2007) http://journals.lww.com/anesthesiology/Fulltext/2007/11000/Dose_dependent_Effects_of_Smoked_Cannab is_on.16.aspx

Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190014/?tool=pubmed

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234438/

Continuous infusion of the cannabinoid WIN 55,212–2 to the site of a peripheral nerve injury reduces mechanical and cold hypersensitivity (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2013951/?tool=pmcentrez

Cannabinoids for postoperative pain. (letter - 2007)

http://journals.lww.com/anesthesiol...00/Cannabinoids_for_Postoperative_Pain.29.asp x

A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/12749972

Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine. (abst - 2007) http://marijuana.researchtoday.net/archive/4/8/1384.htm

Pain relief from cannabis depends on how much you smoke (news - 2007)

http://www.news-medical.net/news/2007/11/26/32855.aspx

Therapeutic potential of cannabis in pain medicine (full - 2008)

http://bja.oxfordjournals.org/cgi/reprint/101/1/59
523

Cannabinoids in the management of difficult to treat pain (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503660/?tool=pmcentrez

Repeated Cannabinoid Injections into the Rat Periaqueductal Gray Enhances Subsequent Morphine Antinociception (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743428/?tool=pmcentrez

Cannabinoids in chronic pain and palliative care. (full - 2008)

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034- 70942008000300010&lng=en&nrm=iso&tlng=en

How Cannabis Compares to other treatments (full- 2008)

http://dcsafeaccess.org/medical/how-cannabis-compares-to-other-treatments/

NOVEL SYNERGISTIC OPIOID-CANNABINOID CODRUG FOR PAIN MANAGEMENT (full - 2008) http://www.freepatentsonline.com/y2008/0176885.html

Cannabinoid Modulation of Cutaneous A{delta} Nociceptors During Inflammation (full - 2008) http://jn.physiology.org/cgi/reprint/100/5/2794

Cannabinoids in chronic pain and palliative care. (full - 2008)
(First in Spanish, then English) http://www.rbaonline.com.br/files/rba/mai08267.pdf

A Randomized, Placebo Controlled Cross-Over Trial of Cannabis Cigarettes in Neuropathic Pain (full - 2008) http://www.cmcr.ucsd.edu/geninfo/Wilsey_2008.pdf

Nabilone for the treatment of pain in fibromyalgia. (abst - 2008)

http://www.ncbi.nlm.nih.gov/pubmed/17974490

Pain relief with cannabinoids-- the importance of endocannabinoids and cannabinoids for pain therapy (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18671173

Marijuana-Based Drug Reduces Fibromyalgia Pain, Study Suggests
(news - 2008) http://www.sciencedaily.com/releases/2008/02/080217214547.htm

Scientist Discovers New Molecule to Treat Chronic Pain (news - 2008)

http://www.physorg.com/news137778721.html

New Cannabis-Like Drugs Could Block Pain Without Affecting Brain, Says Study (news - 2008) http://www.sciencedaily.com/releases/2008/09/080912091728.htm

Cannabis suggests treatment for chronic pain (news - 2008)

http://arstechnica.com/science/news/2008/09/cannabis-suggests-treatment-for-chronic-pain.ars

Dynamic regulation of the endocannabinoid system: implications for analgesia (full - 2009) http://www.molecularpain.com/content/5/1/59
524

The endocannabinoid system and pain. (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834283/?tool=pmcentrez

Cannabinoids: An emerging role in pain management? (full - 2009)

http://www.nursingcenter.com/library/JournalArticle.asp?Article_ID=863277

Standardized natural product cannabis in pain management and observations at a Canadian compassion society: a case report (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740265/?tool=pmcentrez

Systematic Review and Meta-analysis of Cannabis Treatment for Chronic Pain. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19732371

Interaction of the cannabinoid and opioid systems in the modulation of nociception.
(abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19367508?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa nel.Pubmed_RVDocSum&ordinalpos=34

The analgesic potential of cannabinoids. (abst - 2009)

http://www.ncbi.nlm.nih.gov/pubmed/20073408

Characteristics of patients with chronic pain accessing treatment with medical cannabis in Washington State. (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19947069/full_citation/Characteristics_of_patients _with_chronic_pain_accessing_treatment_with_medical_cannabis_in_Washington_State_

Endocannabinoids, Closely Related To Active Ingredients In Cannabis Plant, Can Promote Pain (news - 2009) http://www.sciencedaily.com/releases/2009/09/090911212404.htm

Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878341/?tool=pmcentrez

Adjuvant topical therapy with a cannabinoid receptor agonist in facial postherpetic neuralgia. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19744255

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20176037

Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19896326

Chronic Pain Improved by Cannabis Smoking (news – 2010)

http://news.softpedia.com/news/Chronic-Pain-Improved-by-Cannabis-Smoking-154254.shtml

Study: Smoking pot may ease chronic pain (news - 2010)

http://www.cnn.com/2010/HEALTH/08/30/health.pot.reduce.pain/
525
 
Pages 526 - 530

Marijuana better than pharmaceuticals at treating chronic pain, improving mood (news - 2010) http://www.naturalnews.com/029662_marijuana_chronic_pain.html

Painkilling System in Brain: Too Much of a Good Thing? (news - 2010)

http://www.sciencedaily.com/releases/2010/08/100824151036.htm

Smoking cannabis relieves chronic pain (news – 2010)

http://www.independent.co.uk/life-style/health-and-families/smoking-cannabis-relieves-chronic-pain- 2067287.html

Palmitoylethanolamide reduces granuloma-induced hyperalgesia by modulation of mast cell activation in rats (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034677/?tool=pubmed

Pharmacological characterization of AM1710, a putative cannabinoid CB(2) agonist from the cannabilactone class: Antinociception without central nervous system side-effects. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21382397/abstract/Pharmacological_characterizati on_of_AM1710_a_putative_cannabinoid_CB_2__agonist_from_the_cannabilactone_class:_Antinociceptio n_without_central_nervous_system_side_effects_

Cannabis in Palliative Medicine: Improving Care and Reducing Opioid-Related Morbidity (abst - 2011) http://ajh.sagepub.com/content/early/2011/04/07/1049909111402318.abstract?maxtoshow=&hits=80&RES ULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=H WCIT

Cannabinoid-opioid interaction in chronic pain. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/22048225/abstract/Cannabinoid_opioid_interaction _in_chronic_pain_

Cannabinoids for Treatment of Chronic Non-Cancer Pain; a Systematic Review of Randomized Trials. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21426373

Treating pain in multiple sclerosis. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21916786

Antinociception and sedation following intracerebroventricular administration of Δ9- tetrahydrocannabinol in female vs. male rats. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/20692296/abstract/Antinociception_and_sedation_ following_intracerebroventricular_administration_of_%CE%94%E2%81%B9_tetrahydrocannabinol_in_fe male_vs__male_rats_

Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action
(abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/20942863/abstract/Non_psychoactive_cannabinoid s_modulate_the_descending_pathway_of_antinociception_in_anaesthetized_rats_through_several_mechani sms_of_action_
526

Father: Medical marijuana eased pain of my cancer-battling son (anecdotal – 2011)

http://www.komonews.com/news/local/120941429.html

Marijuana, Narcotics Help Patients Reduce Chronic Pain, Study Finds (news – 2011)

http://www.huffingtonpost.com/2011/12/08/marijuana-narcotics-help-patients-reduce- pain_n_1137416.html

Cannabis brings relief to women suffering from PMS and PMDD symptoms
(news – 2011) http://www.examiner.com/cannabis-revolution-in-las-vegas/cannabis-brings-relief-to-women-suffering- from-pms-and-pmdd-symptoms

Behavioral effects of pulp exposure in mice lacking cannabinoid receptor 2. (abst – 2012)
http://www.ncbi.nlm.nih.gov/pubmed/22152627

PANCREATITIS/ PANCREAS

Pancreatitis & Medical Marijuana (article - no date)

http://onlinepot.org/medical/pancreatitis.htm

The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis. (full - 2005) http://www.jstage.jst.go.jp/article/tjem/207/2/207_99/_article

Gpr40 Gene Expression in Human Pancreas and Insulinoma. (abst – 2005)

http://medical-journals.healia.com/doc/16289108/GPR40-gene-expression-in-human-pancreas-and- insulinoma

Expression of the Gene for a Membrane-bound Fatty Acid Receptor in the Pancreas and Islet Cell Tumours in Humans: Evidence for Gpr40 Expression in Pancreatic Beta Cells and Implications for Insulin Secretion. (abst – 2006)

http://medical-journals.healia.com/doc/16525841/Expression-of-the-gene-for-a-membrane-bound-fatty- acid-receptor-in-the-pancreas-and-islet-cell-tumours-in-humans-evidence-for-GPR40-expression-in- pancreatic-beta-cells-and-implications-for-insulin-secretion

Cannabinoids ameliorate pain and reduce disease pathology in cerulein -induced acute pancreatitis (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268094/?tool=pubmed

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full – 2008) http://gut.bmj.com/content/57/8/1140.full

Cannabinoids Reduce Markers of Inflammation and Fibrosis in Pancreatic Stellate Cells

(full - 2008)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2253501&rendertype=abstract
527

Expression and function of cannabinoid receptors in mouse islets. (full – 2010)

http://www.landesbioscience.com/journals/islets/LiISLETS2-5.pdf

Cannabinoid receptors are coupled to stimulation of insulin secretion from mouse MIN6 beta-cells. (full – 2010) http://content.karger.com/produktedb/produkte.asp?DOI=000320527&typ=pdf

Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.

http://www.ncbi.nlm.nih.gov/pubmed/21346174

Gut feelings about the endocannabinoid system (full – 2011)

http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2011.01689.x/full

(full – 2011)

The role of the endocannabinoid system in islet biology. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21311323

PERINATAL HYPOXIC-ISCHEMIC INJURY - also see STROKES

Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16864698

Synergistic neuroprotective therapies with hypothermia. (full – 2010)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892736/?tool=pubmed

The cannabinoid WIN55212-2 promotes neural repair after neonatal hypoxia-ischemia. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21115947

Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia- ischemia in newborn pigs. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21654550

The Cannabinoid WIN 55212-2 Mitigates Apoptosis and Mitochondrial Dysfunction After Hypoxia Ischemia. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21909954

Cannabinoid as a neuroprotective strategy in perinatal hypoxic-ischemic injury. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21788999

Therapeutic potential of the endocannabinoid system in perinatal asphyxia (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22127663
528

PARKINSON'S DISEASE


Tetrahydrocannabinol potentiates reserpine-induced hypokinesia. (abst – 1981)

http://www.ncbi.nlm.nih.gov/pubmed/6273940

Beneficial and adverse effects of cannabidiol in a Parkinson patient with sinemet-induced dystonic dyskinesia. (abst - 1985)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=142

Open label evaluation of cannabidiol in dystonic movement disorders. (full - 1986)

http://web.acsalaska.net/~warmgun/es017.html

The effects of the cannabinoid receptor agonist nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson's disease (PD). (abst - 1998) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=153

Cannabinoids in parkinsonism (3 abstracts - 1999)

http://www.mdvu.org/emove/article.asp?ID=586

Cannabis in movement disorders. (abst - 1999)

http://www.ncbi.nlm.nih.gov/pubmed/10627163

Why your brain is primed for a high (news - 1999)

http://www.newscientist.com/article/mg16121792.000-why-your-brain-is-primed-for-a-high.html

Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson‘s disease (full - 2000) http://www.fasebj.org/cgi/content/full/14/10/1432?maxtoshow=&hits=10&RESULTFORMAT=&fulltext= cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=20&sortspec=relevance&resourcetype=H WCIT

Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission. (full – 2002) http://www.jneurosci.org/content/22/16/6900.long

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants (full - 2003)

http://www.patentstorm.us/patents/6630507/fulltext.html

Therapeutic potential of cannabinoids in CNS disease. (abst - 2003)

http://www.ncbi.nlm.nih.gov/pubmed/12617697

Survey on cannabis use in Parkinson's disease: subjective improvement of motor symptoms. (abst - 2004) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=33

Marijuana Compounds May Aid Parkinson's Disease (news - 2004)

http://cannabisnews.com/news/19/thread19725.shtml
529

Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1) (full - 2005) http://www.nature.com/tpj/journal/v5/n2/full/6500301a.html

Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/15837565?dopt=Abstract

Cannabinoid control of motor function at the basal ganglia. (abst – 2005)

http://www.ncbi.nlm.nih.gov/pubmed/16596785

Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB1 and TRPV1 receptors (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128772/?tool=pmcentrez

The endocannabinoid system in targeting inflammatory neurodegenerative diseases
(full - 2007) http://medicalcannabis.com/images/pdf09/indications/neurodegenerative/centonze_et_al_2007_inflammato ry_neuro.pdf

Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17196181

Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17287809

Cannabinoids and neuroprotection in motor-related disorders. (abst - 2007)

http://www.ncbi.nlm.nih.gov/pubmed/18220777

Marijuana Against Parkinson? (news – 2007)

http://news.softpedia.com/news/Marijuana-Against-Parkinson-46701.shtml

Marijuana-Like Chemicals Helps Treat Parkinson's (news - 2007)

http://cannabisnews.com/news/22/thread22608.shtml

Parkinsons' Helped By Marijuana-Lke Chemicals In Brain (news – 2007)

http://www.medicalnewstoday.com/releases/62616.php

Enhancing Activity Of Marijuana-Like Chemicals In Brain Helps Treat Parkinson's Symptoms In Mice (news - 2007) http://www.sciencedaily.com/releases/2007/02/070207171915.htm

How Cannabis Compares to other treatments (full - 2008)

http://dcsafeaccess.org/medical/how-cannabis-compares-to-other-treatments/

Paraquat induces apoptosis in human lymphocytes: protective and rescue effects of

glucose, cannabinoids and insulin-like growth factor-1. (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18365879
530
 
Pages 531 - 535

The cannabinoid CP55,940 prolongs survival and improves locomotor activity in Drosophila melanogaster against paraquat: implications in Parkinson's disease. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18538428

Cannabidiol: a promising drug for neurodegenerative disorders? (full - 2009)

http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5949.2008.00065.x/full

WIN55,212-2, a Cannabinoid Receptor Agonist, Protects Against Nigrostriatal Cell Loss in the MPTP Mouse Model of Parkinson‘s Disease (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755595/?tool=pmcentrez

The endocannabinoid system as a target for the treatment of motor dysfunction.
(abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19220290?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa nel.Pubmed_RVDocSum&ordinalpos=54

Cannabidiol for the treatment of psychosis in Parkinson‘s disease (abst - 2009)

http://jop.sagepub.com/cgi/content/abstract/23/8/979?maxtoshow=&hits=80&RESULTFORMAT=&fulltex t=cannabinoid&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT

Cannabinoids and Dementia: A Review of Clinical and Preclinical Data (full – 2010)

http://www.mdpi.com/1424-8247/3/8/2689/pdf

Cannabinoid–Dopamine Interaction in the Pathophysiology and Treatment of CNS Disorders (full – 2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5949.2010.00144.x/full

Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20097273

Cannabinoid receptor agonist protects cultured dopaminergic neurons from the death by the proteasomal dysfunction. (full – 2011) http://acbjournal.org/search.php?where=aview&id=184182&code=1049ACB&vmode=FULL

Therapeutic Potential of Cannabinoids in the Treatment of Neuroinflammation Associated with Parkinson's Disease (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21568925/abstract/Therapeutic_Potential_of_Cann abinoids_in_the_Treatment_of_Neuroinflammation_Associated_with_Parkinson%27s_Disease_

Regional changes in type 1 cannabinoid receptor availability in Parkinson's disease in vivo (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21459482/abstract/Regional_changes_in_type_1_c annabinoid_receptor_availability_in_Parkinson%27s_disease_in_vivo_

Homeostatic changes of the endocannabinoid system in Parkinson's disease.
(abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21412829/abstract/Homeostatic_changes_of_the_e ndocannabinoid_system_in_Parkinson%27s_disease_
531

Prospects for cannabinoid therapies in basal ganglia disorders. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21545415

Symptom-relieving and neuroprotective effects of the phytocannabinoid D(9) -THCV in animal models of Parkinson's disease (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21323909/abstract/Symptom_relieving_and_neuro protective_effects_of_the_phytocannabinoid_D_9___THCV_in_animal_models_of_Parkinson%27s_disea se_

Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22079984

New metabolic pathway for controlling brain inflammation (news – 2011)

http://www.news-medical.net/news/20111021/New-metabolic-pathway-for-controlling-brain- inflammation.aspx

PATENTS RELATED TO CANNABIS

US Patent 4189491 - Tetrahydrocannabinol in a method of treating glaucoma (full - 1980) http://www.patentstorm.us/patents/4189491.html

Process for preparing cannabichromene (full - 1982)

http://www.patentstorm.us/patents/4315862/description.html

Patent 4758597 Carenadiol and derivatives (full – 1988)

http://www.patentstorm.us/patents/4758597/fulltext.html

US Patent 5389375 - Stable suppository formulations effecting bioavailability of Ɗ9 -thc (full - 1995) http://www.patentstorm.us/patents/5389375/fulltext.html

US Patent 5508037 - Stable suppository formulations effecting bioavailability of Ɗ9 - THC (full - 1996) http://www.patentstorm.us/patents/5508037/fulltext.html

Patent 5605928 - Antiemetic compositions (full – 1997)

http://www.patentstorm.us/patents/5605928/fulltext.html

Patent 5631297 - Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same
(full – 1997) http://www.patentstorm.us/patents/5631297/fulltext.html

US Patent 6132762 - Transcutaneous application of marijuana (full - 2000)

http://www.patentstorm.us/patents/6132762/fulltext.html
532

US Patent 6113940 - Cannabinoid patch and method for cannabis transdermal delivery (full – 2000) http://www.patentstorm.us/patents/6113940/fulltext.html

US Patent 6328992 - Cannabinoid patch and method for cannabis transdermal delivery (full - 2001) http://www.patentstorm.us/patents/6328992/fulltext.html

US Patent 6383513 - Compositions comprising cannabinoids (nasal spray) (full - 2002)

http://www.patentstorm.us/patents/6383513/fulltext.html

US Patent Application 20050042172 - Administration of medicaments by vaporisation (full - 2002) http://www.patentstorm.us/applications/20050042172/fulltext.html

Patent 6410588 Use of cannabinoids as anti-inflammatory agents (full – 2002)

http://www.patentstorm.us/patents/6410588/fulltext.html

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants (full - 2003) (Assignee (owner)- the US GOVERNMENT!) http://www.patentstorm.us/patents/6630507/fulltext.html

Patent 6503492 - Antiperspirant or deodorant compositions (full – 2003)

http://www.patentstorm.us/patents/6503492/fulltext.html

20070151149 - Methods for altering the level of phytochemicals in plant cells by applying wave lengths of light from 400 nm to 700 nm and apparatus therefore (full - 2004) http://www.patentstorm.us/applications/20070151149/fulltext.html

US Patent Application 2004004905 - Method for producing an extract from cannabis plant matter, containing a tetrahydrocannabinol and a cannabidiol and cannabis extracts (full - 2004) http://www.freepatentsonline.com/y2004/0049059.html

US Patent 6713048 - Δ9 tetrahydrocannabinol (Δ9 THC) solution metered dose inhalers and methods of use (full - 2004) http://www.patentstorm.us/patents/6713048/fulltext.html

Patent 6713048Δ9 tetrahydrocannabinol (Δ9 THC) solution metered dose inhalers and methods of use (full – 2004) http://www.patentstorm.us/patents/6713048/fulltext.html

US Patent 6974568 - Treatment for cough (full - 2005)

http://www.patentstorm.us/patents/6974568/fulltext.html

US Patent Application 20050266108 - Methods of purifying cannabinoids from plant material (full - 2005) http://www.patentstorm.us/applications/20050266108/fulltext.html

US Patent Application 20050079136 - Aerosol formulations of delta

tetrahydrocannabinol (full – 2005)

http://www.patentstorm.us/applications/20050079136/fulltext.html
533

US Patent 6949582 - Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment (full - 2005) http://www.patentstorm.us/patents/6949582/fulltext.html

20050070596 - Methods for treatment of inflammatory diseases using CT-3 or analogs thereof (full - 2005) http://www.patentstorm.us/applications/20050070596/fulltext.html

Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment (full - 2005) http://www.patentstorm.us/patents/6949582/fulltext.html

US Patent Application 20060160888 - Room-temperature stable dronabinol formulations (full – 2006) http://www.patentstorm.us/applications/20060160888/fulltext.html

US Patent 7088914 - Device, method and resistive element for vaporizing a medicament (full - 2006) http://www.patentstorm.us/patents/7088914/fulltext.html

US Patent Application 20060167084 - Delta-9-THC compositions and methods for treating symptoms associated with multiple sclerosis (full - 2006 ) http://www.patentstorm.us/applications/20060167084/fulltext.html

US Patent 7025992 - Pharmaceutical formulations (full - 2006)

http://www.patentstorm.us/patents/7025992/fulltext.html

US Patent Application 20060039959 - Film-Shaped Mucoadhesive Administration Forms For Administering Cannabis Agents (full – 2006) http://www.patentstorm.us/applications/20060039959/fulltext.html

US Patent Application 20060242899 - Method of cultivating plants full - 2006)

http://www.freepatentsonline.com/y2006/0242899.html

US Patent 7109245 - Vasoconstrictor cannabinoid analogs (full - 2006)

http://www.patentstorm.us/patents/7109245/fulltext.html

US Patent Application 20070020193 - Dronabinol compositions and methods for using same (full – 2007) http://www.patentstorm.us/applications/20070020193/fulltext.html

20080057117 - PHARMACEUTICAL COMPOSITION MADE UP OF CANNIBUS EXTRACTS (full - 2007) http://www.patentstorm.us/applications/20080057117/fulltext.html

US Patent Application 20070041994 - Compositions and methods for treating prostate disorders ( full – 2007) http://www.patentstorm.us/applications/20070041994/fulltext.html

US Patent Application 20070049645 - Anti-nausea and anti-vomiting activity of cannabidiol compounds (full – 2007) http://www.patentstorm.us/applications/20070049645/fulltext.html

US Patent Application 20070099987 - Treating or preventing diabetes with cannabidiol (full – 2007) http://www.patentstorm.us/applications/20070099987/fulltext.html
534

Patent 7344736 - Extraction of pharmaceutically active components from plant materials (full – 2008) http://www.patentstorm.us/patents/7344736/description.html

20080275237 - Method for Obtaining Pure Tetrahydrocannabinol (full – 2008)

http://www.faqs.org/patents/app/20080275237

US Patent 7402686 - Cannabinoid crystalline derivatives and process of cannabinoid purification (full - 2008) http://www.patentstorm.us/patents/7402686/fulltext.html

US Patent 7399872 - Conversion of CBD to Δ-THC and Δ-THC (full - 2008)

http://www.patentstorm.us/patents/7399872/fulltext.html

US Patent Application 20080112895 - Aqueous dronabinol formulations (full – 2008)

http://www.patentstorm.us/applications/20080112895/fulltext.html

US Patent Application 20080181942 - Delta-9-THC compositions and methods for treating symptoms associated with multiple sclerosis (full – 2008) http://www.patentstorm.us/applications/20080181942/fulltext.html

US Patent Application 20080262099 - Inhibition of Tumour Cell Migration (full – 2008) http://www.patentstorm.us/applications/20080262099/fulltext.html

Op-Ed: US Government Holds Patent For Medical Marijuana, Shows Hypocrisy (news – 2008) http://www.digitaljournal.com/article/257008

Patent 7524881 - Production of Δ 9 tetrahydrocannabinol (full – 2009)

http://www.patentstorm.us/patents/7524881/fulltext.html

US Patent Application 20090324797 - MODULATING PLANT OIL LEVELS (full – 2009) http://www.patentstorm.us/applications/20090324797/fulltext.html

US Patent 7622140 - Processes and apparatus for extraction of active substances and enriched extracts from natural products (full - 2009) http://www.patentstorm.us/patents/7622140/fulltext.html

US Patent Application 20090197941 - Pharmaceutical Compositons for the Treatment of Chronic Obstructive Pulmonary Disease (full – 2009) http://www.patentstorm.us/applications/20090197941/fulltext.html

US Patent Application 20090005461 - Use of Cannabidiol in the Treatment of Hepatitis (full – 2009) http://www.patentstorm.us/applications/20090005461/fulltext.html

NEW USE FOR CANNABINOID-CONTAINING PLANT EXTRACTS

Patent application number: 20100249223 (full - 2010)

http://www.faqs.org/patents/app/20100249223
535
 
Pages 536 - 540

CANNABINOID-CONTAINING PLANT EXTRACTS AS NEUROPROTECTIVE AGENTS Patent application number: 20100239693 (full - 2010) http://www.faqs.org/patents/app/20100239693

Patent application title: PHARMACOLOGICAL TREATMENT OF PSORIASIS (full – 2010) http://www.faqs.org/patents/app/20080255224

US Patent Application 20100012118 - Medicament dosage for inhaler

http://www.patentstorm.us/applications/20100012118/fulltext.html

Patent 7741365 Peripheral cannabinoid receptor (CB2) selective ligands (full – 2010) http://www.patentstorm.us/patents/7741365/fulltext.html

Patent 7816143 Oral detection test for cannabinoid use (full - 2010)

http://www.patentstorm.us/patents/7816143/fulltext.html

(full – 2010)

US Patent Application 20100204312 - METHODS AND COMPOSITIONS FOR TREATING CANCER (full - 2010) http://www.patentstorm.us/applications/20100204312/fulltext.html

US Patent Application 20100158973 - THERAPEUTIC USES OF CANNABIDIOL COMPOUNDS (full – 2010) http://www.patentstorm.us/applications/20100158973/fulltext.html

US Patent Application 20110097283 - CHEWING GUM COMPOSITIONS COMPRISING CANNABINOIDS (full – 2011) http://www.patentstorm.us/applications/20110097283/fulltext.html

US Patent Application 20110052694 - USE OF CANNABIDIOL PRODRUGS IN TOPICAL AND TRANSDERMAL ADMINISTRATION WITH MICRONEEDLES (full – 2011) http://www.patentstorm.us/applications/20110052694/fulltext.html

US Patent Application 20110073120 - Smoke and Odor Elimination Filters, Devices and Methods (full – 2011) http://www.patentstorm.us/applications/20110073120/fulltext.html

US Patent Application 20110020945 - ORAL DETECTION TEST FOR CANNABINOID USE (full – 2011) http://www.patentstorm.us/applications/20110020945/fulltext.html

US Patent Application 20110082195 - NEW USE FOR CANNABINOIDS (full – 2011) http://www.patentstorm.us/applications/20110082195/fulltext.html
536

PEA – PALMITOYLETHANOLAMIDE
- endocannabinoid , GPR55 & GPR119 agonist

Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase
and enhances the anti-proliferative effect of anandamide in human breast cancer cells (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222054/pdf/11485574.pdf/?tool=pmcentrez

Anticonvulsant activity of N-palmitoylethanolamide, a putative endocannabinoid, in mice. (abst – 2001) http://www.ncbi.nlm.nih.gov/pubmed/11442148

Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat (full - 2002)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1573125&tool=pmcentrez

The search for the palmitoylethanolamide receptor. (abst – 2005)

http://www.ncbi.nlm.nih.gov/pubmed/15963531

Finding of endocannabinoids in human eye tissues: implications for glaucoma. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/15823551

Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/15461672

Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/17011761

Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury. (full – 2008) http://jpet.aspetjournals.org/content/326/1/12.long

Adjuvant treatment of atopic eczema: assessment of an emollient containing N- palmitoylethanolamine (ATOPA study). (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18181976

Anti-inflammatory effect of palmitoylethanolamide on human adipocytes. (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19131941

Protective role of palmitoylethanolamide in contact allergic dermatitis. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/19909294

Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/19931394

Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/19840245
537

Misdiagnosed chronic pelvic pain: pudendal neuralgia responding to a novel use of palmitoylethanolamide. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20345619

Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20176435

Protective role of palmitoylethanolamide in contact allergic dermatitis. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/19909294

Chocolate: The Good, the Bad and the Angry (news - 2010)

http://www.psychologytoday.com/blog/your-brain-food/201011/chocolate-the-good-the-bad-and-the-angry

Increasing Antiproliferative Properties of Endocannabinoids in N1E-115 Neuroblastoma Cells through Inhibition of Their Metabolism. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203169/?tool=pubmed

Administration of URB597, oleoylethanolamide or palmitoylethanolamide increases waking and dopamine in rats. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136458/?tool=pubmed

Palmitoylethanolamide reduces granuloma-induced hyperalgesia by modulation of mast cell activation in rats (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034677/?tool=pubmed

Palmitoylethanolamide counteracts reactive astrogliosis induced by beta-amyloid peptide. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21255263

Use of palmitoylethanolamide in the entrapment neuropathy of the median in the wrist. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21483401

Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21354467

Effects of palmitoylethanolamide on the cutaneous allergic inflammatory response in Ascaris hypersensitive Beagle dogs. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21601500

PHARC

Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of

endocannabinoid metabolism. (full – 2011)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933347/?tool=pubmed
538

The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2‐arachidonoylglycerol signalling through cannabinoid receptors (full – 2011)

http://onlinelibrary.wiley.com/doi/10.1111/j.1748-1716.2011.02280.x/full

The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2- arachidonoylglycerol signalling through cannabinoid receptors. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21418147

PHYTOCANNABINOIDS/ PLANT EXTRACTS - also see THC, CBD

ACCESSING 0.5 to 2.0 GRAMS CBD FRACTIONATING THE PHYTOCANNABINOIDS BY THEIR VAPORIZATION POINTS (article - no date ) http://forum.grasscity.com/medical-marijuana/610429-need-cbd.html

Cannabinoids (encyclopedia entry) http://www.chemie.de/lexikon/e/Cannabinoids/ Cannabis Indica (U. S. P.)—Indian Cannabis. King's American Dispensatory (1898)

http://www.henriettesherbal.com/eclectic/kings/cannabis.html

Chemical basis of hashish activity. (abst - 1970)

http://www.ncbi.nlm.nih.gov/pubmed/4987683

Anticonvulsant Action of Cannabis in the Rat: Role of Brain Monoamines. (abst – 1978)

http://www.ncbi.nlm.nih.gov/pubmed/104333

Intraocular pressure following systemic administration of cannabinoids. (abst - 1982)

http://www.ncbi.nlm.nih.gov/pubmed/6295702

Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol. (abst – 1984) http://www.ncbi.nlm.nih.gov/pubmed/6098513

Side effects of pharmaceuticals not elicited by comparable herbal medicines: the case of tetrahydrocannabinol and marijuana. (abst – 1999) http://www.ncbi.nlm.nih.gov/pubmed/10394675

Advantages of polypharmaceutical herbal cannabis compared to single ingredient, synthetic tetrahydrocannabinol (full - 2000) http://www.cannabis-science.com/papers/cannabis terpenes.pdf

Immunoactive cannabinoids: Therapeutic prospects for marijuana constituents (full - 2000) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC34030/?tool=pubmed

Variations of D9-THC content in single plants of hemp varieties (full - 2000)

http://www.ukcia.org/research/VariationOfTHCContent.pdf
539

Cannabinoids in clinical practice. (abst - 2000)

http://www.ncbi.nlm.nih.gov/pubmed/11152013

Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts? (full - 2001)

http://www.cannabis-med.org/membersonly/mo.php?aid=2001-03-04&fid=2001-03-04-7&mode=p&sid=

Chapter 3: Cannabis and Marinol Compared (book excerpt - 2001)

http://www.or-coast.net/contigo/PDF 1 Files/chpt_3.pdf

Natural cannabis 'better than extracts' (news - 2001)

http://news.bbc.co.uk/2/hi/health/1261737.stm

Whether whole plant Cannabis extracts can improve intractable neurogenic symptoms? (full - 2003) http://www.ukcia.org/research/WholePlantExtractsImproveNeurogenicSymptoms.pdf

Cannabis can help MS sufferers (news - 2003)

http://www.newscientist.com/article/dn4356-cannabis-can-help-ms-sufferers.html

Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study. (full - 2004) http://www.ukcia.org/research/EfficacySafetyTolerabilityInMSSpasticityTreatment.pdf

Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 ̳N of 1‘ studies (full - 2004) http://www.ukcia.org/research/InitialExperiencesChronicPain.pdf

Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial (full - 2004) http://www.ukcia.org/research/CentralNeuropathicPainEfficacy.pdf

Cannabis truly helps multiple sclerosis sufferers (news - 2004)

http://www.newscientist.com/article/dn6387-cannabis-truly-helps-multiple-sclerosis-sufferers.html

Plant cannabinoids: a neglected pharmacological treasure trove. (full - 2005)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751232/?tool=pubmed

Chemical constituents of marijuana: the complex mixture of natural cannabinoids. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/16199061

A tale of two cannabinoids:The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. (full - 2006) http://mcforadhd.free.fr/Russo_Tale_of_Two_Cannabinoids_Med_Hypoth_2006.pdf

Unheated Cannabis sativa extracts and its major compound THC-acid have potential immuno-modulating properties not mediated by CB1 and CB2 receptor coupled pathways. (abst - 2006)
http://www.ncbi.nlm.nih.gov/pubmed/16504929
540
 
Pages 541 - 545

The psychoactive plant cannabinoid, Delta9-tetrahydrocannabinol, is antagonized by Delta8- and Delta9-tetrahydrocannabivarin in mice in vivo. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189766/?tool=pubmed

The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190019/?tool=pubmed

Endocannabinoids and Related Compounds: Walking Back and Forth between Plant Natural Products and Animal Physiology (full - 2007) http://www.sciencedirect.com/science/article/pii/S1074552107002062

Medicinal chemistry endeavors around the phytocannabinoids. (abst - 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17712816

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9- tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/

Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. (full - 2008) http://www.cannabisasmedicine.com/story/antibacterial-cannabinoids-cannabis-sativa- structure%E2%88%92activity-study

Pain relief with cannabinoids-- the importance of endocannabinoids and cannabinoids for pain therapy (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18671173

Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain: mechanisms involved. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18618522

Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1). (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18619955

Immunomodulatory lipids in plants: plant fatty acid amides and the human endocannabinoid system. (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/18275004

PKS activities and biosynthesis of cannabinoids and flavonoids in Cannabis sativa L. plants (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18854334

Non-psychotropic plant cannabinoids:new therapeutic opportunities from an ancient herb (full - 2009 )
http://cannabisinternational.org/info/Non-Psychoactive-Cannabinoids.pdf

1.0 Chemistry (full - 2009)

http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/chemistry-chimie- eng.php#a1_1
541

Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697695/?tool=pubmed

Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765124/?tool=pubmed

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19729208

Phytocannabinoids and endocannabinoids. (abst - 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19630737

Pharmacological and therapeutic secrets of plant and brain (endo)cannabinoids. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/18777572

Phytocannabinoid scientists unveils lozenge to treat H1N1 swine flu and H5N1 bird flu (news/ad - 2009) http://www.examiner.com/examiner/x-7002-Pittsburgh-History-Examiner~y2009m6d11- Phytocannabinoid-scientists-unveils-lozenge-to-treat--H1N1-swine-flu-and-H5N1-bird-flu#comments

Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866040/?tool=pubmed

The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931567/?tool=pubmed

Phytocannabinoids beyond the Cannabis plant – do they exist? (full - 2010)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931553/?tool=pubmed

Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels. (abst – 2010)

http://www.unboundmedicine.com/medline/ebm/record/19847654/abstract/Non_CB1_non_CB2_receptors _for_endocannabinoids_plant_cannabinoids_and_synthetic_cannabimimetics:_focus_on_G_protein_couple d_receptors_and_transient_receptor_potential_channels_

A low-Δ9tetrahydrocannabinol cannabis extract induces hyperphagia in rats. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20975531

Cannabis constituents modulate δ9-tetrahydrocannabinol-induced hyperphagia in rats. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20349049

Preliminary efficacy and safety of an oromucosal standardized cannabis extract in

chemotherapy-induced nausea and vomiting. (abst - 2010)

http://www.ncbi.nlm.nih.gov/pubmed/21039759
542

Scientists Find New Sources of Plant Cannabinoids Other than Medical Marijuana? (news – 2010) http://montanabiotech.wordpress.com...find-new-sources-of-plant-cannabinoids-other- than-medical-marijuana/

Nature's (Legal) Cannabinoids (news - 2010)

http://www.mapinc.org/drugnews/v10/n126/a04.html?1194

Gut feelings about the endocannabinoid system (full – 2011)

http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2011.01689.x/full

Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa. (full – 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf

Treatment of Crohn's disease with cannabis: an observational study. (full – 2011)

http://www.ima.org.il/imaj/ar11aug-01.pdf

The role of phytochemicals in the treatment and prevention of dementia. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21639405/abstract/The_role_of_phytochemicals_i n_the_treatment_and_prevention_of_dementia_

Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21674569

Prospects for cannabinoid therapies in basal ganglia disorders. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21545415

Cannabinoids: occurrence and medicinal chemistry. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21254969/abstract/Cannabinoids:_occurrence_and _medicinal_chemistry_

Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21749363

Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21094240

Phytocannabinoids as novel therapeutic agents in CNS disorders (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21924288

Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21213357

Non-Δ9tetrahydrocannabinol phytocannabinoids stimulate feeding in rats. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22157176
543

The Endocannabinoid System: Plant-Derived Cannabinoids in Diabetes and Diabetic Complications. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22155112

Marijuana, endocannabinoids, and epilepsy: Potential and challenges for improved therapeutic intervention. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/22178327

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21175579/abstract/Effects_of_cannabinoids_and_c annabinoid_enriched_Cannabis_extracts_on_TRP_channels_and_endocannabinoid_metabolic_enzymes_

POISONING - ORGANOPHOSPHATE

Modulation of paraoxon toxicity by the cannabinoid receptor agonist WIN 55,212-2. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16956707

Monoacylglycerol lipase inhibition by organophosphorus compounds leads to elevation of brain 2-arachidonoylglycerol and the associated hypomotility in mice. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16310817

Activation of the endocannabinoid system by organophosphorus nerve agents (abst - 2008) http://www.nature.com/nchembio/journal/v4/n6/abs/nchembio.86.html

Behavioral sequelae following acute diisopropylfluorophosphate intoxication in rats: comparative effects of atropine and cannabinomimetics. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854260/?tool=pubmed

Cannabinoid Receptor Agonist WIN-55,212-2 Protects Differentiated PC12 Cells From Organophosphorus- Induced Apoptosis (abst – 2010) http://ijt.sagepub.com/content/29/2/201.abstract

Effect of Developmental Chlorpyrifos Exposure on Endocannabinoid Metabolizing Enzymes in the Brain of Juvenile Rats. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21507991

Comparative effects of chlorpyrifos in wild type and cannabinoid Cb1 receptor knockout mice. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21672545

POISONING - PARAQUAT

An effect of paraquat on the lungs of rabbits. Its implications in smoking contaminated marihuana. (full - 1978) http://chestjournal.chestpubs.org/content/74/4/418.long
544

Paraquat goes to pot. (full - 1978) http://chestjournal.chestpubs.org/content/74/4/358.long Paraquat and marihuana. Assessing the hazard. (full - 1978)

http://chestjournal.chestpubs.org/content/74/4/357.long

Paraquat and marijuana: epidemiologic risk assessment. (full -1983)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1650884&tool=pmcentrez

Paraquat induces apoptosis in human lymphocytes: protective and rescue effects of glucose, cannabinoids and insulin-like growth factor-1. (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/18365879

The cannabinoid CP55,940 prolongs survival and improves locomotor activity in Drosophila melanogaster against paraquat: implications in Parkinson's disease. (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/18538428

Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20514518

POST-OPERATIVE PAIN

Cannabinoid CB2 receptor agonist activity in the hindpaw incision model of postoperative pain. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16316653

A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain management. (full - 2006) http://journals.lww.com/anesthesiology/Fulltext/2006/05000/A_Multicenter_Dose_escalation_Study_of_th e.21.aspx

Analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=184

Delta(9)-tetrahydrocannabinol and the opioid receptor agonist piritramide do not act synergistically in postoperative pain (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16389542

Cannabis effective at relieving pain after major surgery (news - 2006)

http://www.news-medical.net/news/2006/05/17/17995.aspx

Cannador: Drug from cannabis plant-extract to reduce surgery pain (news - 2006)

http://www.ecofriend.org/entry/cannador-drug-from-cannabis-plant-extract-to-reduce-surgery-pain/
545
 
Pages 546 - 550

Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision. (full - 2007) http://journals.lww.com/anesthesiology/pages/articleviewer.aspx?year=2007&issue=04000&article=00021 &type=abstract

Cannabinoid Receptor Agonist Significantly Reduces Post-Operative Pain, Study Says (news – 2007) http://norml.org/index.cfm?Group_ID=7246

Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878341/?tool=pmcentrez

Compound boosts marijuana-like chemical in the body to relieve pain at injury site (news - 2010) http://www.eurekalert.org/pub_releases/2010-09/uoc--cbm092010.php

POST TRAUMATIC STRESS DISORDER/ PTSD

Never fear, cannabinoids are here (article - 2002)

http://mcforadhd.free.fr/naturefear.pdf

The endogenous cannabinoid system controls extinction of aversive memories. (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12152079

'Natural' cannabis manages memory (news - 2002)

http://news.bbc.co.uk/2/hi/health/2163405.stm

Study: Marijuana Eases Traumatic Memories (news - 2002)

http://cannabisnews.com/news/13/thread13601.shtml

Cannabis-like Brain Chemical Blocks Out Bad Memories (news - 2002)

http://www.scientificamerican.com/article.cfm?id=cannabis-like-brain-chemi

Endocannabinoids extinguish bad memories in the brain (news - 2002)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=123#1

Marijuana-Like Compound Banishes Fear (news - 2002)

http://www.webmd.com/anxiety-panic/news/20020802/marijuana-like-compound-banishes-fear

Natural high helps banish bad memories (news - 2002)

http://www.newscientist.com/article/dn2616-natural-high-helps-banish-bad-memories.html

Israel to soothe soldiers with marijuana (news - 2004)

http://newsmine.org/content.php?ol=war-on-terror/israel/israel-to-soothe-soldiers-with-marijuana.txt
546

Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html

Cannabinoid CB1 Receptor Mediates Fear Extinction via Habituation-Like Processes (full - 2006) http://www.jneurosci.org/cgi/content/full/26/25/6677?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT

Aversive memory reactivation engages in the amygdala only some neurotransmitters involved in consolidation. (full – 2006) http://learnmem.cshlp.org/content/13/4/426.long

PTSD and Cannabis: A Clinician Ponders Mechanism of Action (news - 2006)

http://ccrmg.org/journal/06spr/perspective2.html

Cannabis Eases Post Traumatic Stress (news - 2006)

http://ccrmg.org/journal/06spr/ptsd.html

Modulation of Fear and Anxiety by the Endogenous Cannabinoid System (full - 2007)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789283/?tool=pmcentrez

Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. (full – 2007) http://www.nature.com/npp/journal/v32/n5/pdf/1301224a.pdf

Posttraumatic stress symptom severity predicts marijuana use coping motives among traumatic event-exposed marijuana users (abst - 2007) http://marijuana.researchtoday.net/archive/4/8/1378.htm

Medical Marijuana: PTSD Medical Malpractice (news - 2007)

http://salem-news.com/articles/june142007/leveque_61407.php

Cannabis for the Wounded - Another Walter Reed Scandal (news - 2007)

http://www.libertypost.org/cgi-bin/readart.cgi?ArtNum=179973&Disp=11

Association of the Cannabinoid Receptor Gene (CNR1) With ADHD and Post-Traumatic Stress Disorder (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685476/?tool=pubmed

Marijuana Therapy for Veterans with PTSD (article – 2008)

http://www.benefitsofmarijuana.com/ask/reader-questions/marijuana-therapy-for-veterans-with-ptsd/

Cannabinoid Receptor Activation in the Basolateral Amygdala Blocks the Effects of Stress on the Conditioning and Extinction of Inhibitory Avoidance (full - 2009) http://www.jneurosci.org/cgi/content/full/29/36/11078?maxtoshow=&hits=10&RESULTFORMAT=&fullt ext=Dr.+Irit+Akirav+&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

The use of a synthetic cannabinoid in the management of treatment-resistant nightmares

in posttraumatic stress disorder (PTSD). (abst - 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19228182?dopt=Abstract
547

Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications (abst – 2009) http://pharmgkb.org/pmid/19897083

Patients with post-traumatic stress disorder may benefit from synthetic marijuana
(news - 2009) http://www.healthjockey.com/2009/11...t-traumatic-stress-disorder-may-benefit-from- synthetic-marijuana/

Marijuana could alleviate symptoms of PTSD (news - 2009)

http://israel21c.org/health/marijuana-could-alleviate-symptoms-of-ptsd

Marijuana could prove helpful for post-traumatic stress disorder patients. (news - 2009)

http://www.thefreelibrary.com/Marijuana+could+prove+helpful+for+post-traumatic+stress+disorder...- a0211332139

'Pot' may help combat PTSD U. of Haifa study shows (news - 2009)

http://www.vawatchdog.org/09/nf09/nfnov09/nf110509-7.htm

PTSD contributes to teen and young adult cannabis use disorders. (full – 2010)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784238/?tool=pubmed

Cannabinoids modulate hippocampal memory and plasticity. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/19830813

The relationship between substance use and posttraumatic stress disorder in a methadone maintenance treatment program. (abst – 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=309

V.A. Easing Rules for Users of Medical Marijuana (news – 2010)

http://www.nytimes.com/2010/07/24/health/policy/24veterans.html

Cannabis and PTSD by Michael McKenna (anecdotal - 2010)

http://marijuana-uses.com/cannabis-and-ptsd-by-michael-mckenna/

The role of cannabinoids in modulating emotional and non-emotional memory processes in the hippocampus. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124830/?tool=pubmed

Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress. (full – 2011) http://www.nature.com/npp/journal/v37/n2/full/npp2011204a.html

Cannabinoids Prevent the Development of Behavioral and Endocrine Alterations in a Rat Model of Intense Stress. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21918506

Posttraumatic stress disorder and Cannabis use in a nationally representative sample. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21480682
548

Cannabinoid receptor expression and phosphorylation are differentially regulated between male and female cerebellum and brain stem after repeated stress: Implication for PTSD and drug abuse. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21600961

Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21867717

Cannabinoids Prevent the Development of Behavioral and Endocrine Alterations in a Rat Model of Intense Stress. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21918506

Anti-Aversive Effects of Cannabidiol on Innate Fear-Induced Behaviors Evoked by an Ethological Model of Panic Attacks Based on a Prey vs the Wild Snake Epicrates cenchria crassus Confrontation Paradigm. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21918503

Medical cannabis use in post-traumatic stress disorder: a naturalistic observational study. (abst – 2011) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=481

Cannabis use among military veterans after residential treatment for posttraumatic stress disorder. (abst – 2011) http://marijuana.researchtoday.net/archive/8/9/5260.htm

Marijuana Administration After a Traumatic Experience May Prevent Post-Traumatic Stress Symptoms, Rat Study Suggests (news – 2011) http://www.sciencedaily.com/releases/2011/09/110921120037.htm

Medical marijuana turns former soldier's life around (news – 2011)

http://www.examiner.com/cannabis-culture-in-phoenix/medical-marijuana-turns-former-soldier-s-life- around

Marijuana blocks PTSD symptoms in rats: study (news - 2011)

http://medicalxpress.com/news/2011-09-marijuana-blocks-ptsd-symptoms-rats.html

Opposing Roles for Cannabinoid Receptor Type-1 (CB(1)) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21937980

PRADER WILLI SYNDROME

Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038245/?tool=pubmed
549

PREGNANCY/ PRENATAL EXPOSURE


also see PERINATAL HYPOXIC-ISCHEMIC INJURY, CHILDREN

Hemp Packs in Powerful Source of Preconception Nutrition (article - no date)

http://manitobaharvest.com/articles_studies/3812/Hemp-Packs-in-Powerful-Source-of-Preconception- Nutrition.html

Effects of Alcohol and Cannabis during Labor. (article - 1930) (on page 2)

http://jama.ama-assn.org/cgi/reprint/94/15/1164- a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=3360&res ourcetype=HWCIT

Nonmutagenic action of cannabinoids in vitro (abst - 1978)

http://content.karger.com/ProdukteDB/produkte.asp?Doi=136789

Teratologic evaluation of synthetic delta 9-tetrahydrocannabinol in rabbits. (abst – 1979) http://www.ncbi.nlm.nih.gov/pubmed/473088

Acute effects of marihuana smoking on prolactin levels in human females.

(abst - 1985)
http://jpet.aspetjournals.org/content/232/1/220.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Effects of prenatal exposure to cannabinoids. (abst – 1985)

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=3929130&dopt=abstract plus

Tolerance to the luteinizing hormone and prolactin suppressive effects of delta-9-

tetrahydrocannabinol develops during chronic prepubertal treatment of female rats.

(abst - 1986)

http://jpet.aspetjournals.org/content/238/3/1034.abstract?maxtoshow=&hits=80&RESULTFORMAT=&ful ltext=cannabis&searchid=1&FIRSTINDEX=3760&resourcetype=HWCIT

A comparison of the effects of prenatal exposure to tobacco, alcohol, cannabis and caffeine on birth size and subsequent growth (abst - 1987) http://www.ncbi.nlm.nih.gov/pubmed/3657756

Poor and pregnant: perinatal ganja use in rural Jamaica. (abst – 1989)

http://www.ncbi.nlm.nih.gov/pubmed/2785329

Marijuana Use in Pregnancy and Pregnancy Outcome. (abst – 1990)

https://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-999442

Five-year follow-up of rural Jamaican children whose mothers used marijuana during pregnancy. (abst – 1991) http://www.ncbi.nlm.nih.gov/pubmed/1957518
550
 
Pages 551 - 555

Prenatal marijuana use and neonatal outcome. (abst – 1991)

http://www.ncbi.nlm.nih.gov/pubmed/1886543

Analysis of Facial Shape in Children Gestationally Exposed to Marijuana, Alcohol, and/or Cocaine (abst - 1992) http://pediatrics.aappublications.org/cgi/content/abstract/89/1/67?maxtoshow=&hits=80&RESULTFORM AT=&fulltext=marihuana&searchid=1&FIRSTINDEX=960&resourcetype=HWCIT

Tobacco and marijuana use on offspring growth from birth through 3 years of age.
(abst - 1992) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=1488035 &ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

THREE THINGS MARIJUANA DOESN'T DO (news - 1992)

http://www.ukcia.org/research/mjfaq2.php

Prenatal Marijuana Exposure and Neonatal Outcomes in Jamaica : An Ethnographic Study (full - 1994) http://www.druglibrary.org/Schaffer/hemp/medical/can-babies.htm

The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. (full - 1995) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC40821/

Prenatal exposure to marihuana and tobacco during infancy, early and middle childhood: effects and an attempt at synthesis. (abst – 1995) http://www.ncbi.nlm.nih.gov/pubmed/7786162

Prenatal tobacco and marijuana use among adolescents: effects on offspring gestational age, growth, and morphology. (abst – 1995)
http://www.ncbi.nlm.nih.gov/pubmed/7724314

Mortality Within the First 2 Years in Infants Exposed to Cocaine, Opiate, or Cannabinoid During Gestation (abst - 1997) http://pediatrics.aappublications.org/cgi/content/abstract/100/1/79?maxtoshow=&hits=80&RESULTFORM AT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=640&resourcetype=HWCIT

Maternal cannabis use and birth weight: a meta-analysis (abst – 1997)

http://www.ingentaconnect.com/content/carfax/cadd/1997/00000092/00000011/art00015

Use of Marijuana During Pregnancy (book excerpt - 1997)

http://www.mothering.com/pregnancy-birth/use-of-marijuana-during-pregnancy

Dr. Melanie Dreher, reefer researcher (interview - 1998)

http://www.cannabisculture.com/v2/articles/1404.html

Cannabis and pregnancy (full - 1999)

http://www.ukcia.org/research/CannabisAndPregnancy.php

Ganja mothers, ganja babies (news - 1999)

http://www.cannabisculture.com/articles/1422.html
551

Dysregulated Cannabinoid Signaling Disrupts Uterine Receptivity for Embryo Implantation (full - 2001) http://www.jbc.org/content/276/23/20523.full

Menstrual cramps, morning sickness and labour pain (anecdotal – 2001)

http://www.ukcia.org/medical/showmedicaltestimony.php?articleid=12

Contrasting effects of WIN 55212-2 on motility of the rat bladder and uterus. (full – 2002) http://www.jneurosci.org/content/22/16/7147.long

Cannabis Treatments in Obstetrics and Gynecology: A Historical Review (full - 2002) http://www.cannabis-med.org/data/pdf/2002-03-04-1_0.pdf

Prenatal Marijuana Use and Neonatal Outcome. (abst – 2002)

http://medical-journals.healia.com/doc/1886543/Prenatal-marijuana-use-and-neonatal-outcome

Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat? (abst - 2002) http://haworthpress.com/store/ArticleAbstract.asp?ID=18139

Maternal use of cannabis and pregnancy outcome. (abst – 2002)

http://www.ncbi.nlm.nih.gov/pubmed/11843371

Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1721515/pdf/v088p00F98.pdf

Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/12678501

The Endocannabinoid-CB Receptor System: Importance for development and in pediatric disease (full - 2004) http://www.nel.edu/pdf_/25_12/NEL251204A01_Fride_.pdf

Plasma Levels of the Endocannabinoid Anandamide in Women—A Potential Role in Pregnancy Maintenance and Labor? (full - 2004) http://jcem.endojournals.org/cgi/content/full/89/11/5482?ijkey=5e8ec5690352ba9f6b990355b2ed69b1d2e5 8a5b

Aberrant cannabinoid signaling impairs oviductal transport of embryos. (abst - 2004)

http://www.ncbi.nlm.nih.gov/pubmed/15378054

Use of anti-emetic herbs in pregnancy: women's choices, and the question of safety and efficacy (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/14744504

Cannabinoids and the human uterus during pregnancy (abst - 2004)

http://www.ncbi.nlm.nih.gov/pubmed/14749627

The cannabinoid system and its importance in the perinatal period (abst – 2005)

http://www.ncbi.nlm.nih.gov/pubmed/16266619
552

Determination of the prevalence of drug misuse by meconium analysis (full - 2006)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672735/?tool=pubmed

Survey of medicinal cannabis use among childbearing women: patterns of its use in pregnancy and retroactive self-assessment of its efficacy against 'morning sickness'. (full – 2006) http://safeaccess.ca/research/cannabis_nausea2006.pdf

Parental marijuana use and risk of childhood acute myeloid leukaemia: a report from the Children's Cancer Group (United States and Canada). (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16466429

Prenatal exposure to a cannabinoid receptor agonist does not affect sensorimotor gating in rats (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16423346

More Pregnancy Highs Than Lows (news - 2006)

http://www.thehempire.com/index.php/cannabis/news/more_pregnancy_highs_than_lows

Oily fish makes 'babies brainier' (news - 2006) (hemp seed - at the end)

http://news.bbc.co.uk/2/hi/health/4631006.stm

Dreher's Jamaican Pregnancy Study (news - 2006)

http://www.november.org/stayinfo/breaking06/DreherStudy.html

Cannabis Relieves Morning Sickness (news - 2006)

http://ccrmg.org/journal/06spr/dreher.html#morning

The role of the endocannabinoid system in gametogenesis, implantation and early pregnancy (full - 2007) http://humupd.oxfordjournals.org/cgi/content/full/13/5/501?maxtoshow=&hits=80&RESULTFORMAT=& fulltext=cannabinoid&searchid=1&FIRSTINDEX=960&resourcetype=HWCIT

Prevalence of gestational exposure to cannabis in a Mediterranean city by meconium analysis. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17953730

Breathe, Push, Puff? Pot Use and Pregnancy: A Review of the Literature (news – 2007)

http://norml.org/index.cfm?Group_ID=8060

CB2 receptors in reproduction (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219526/

Volumetric MRI Study of Brain in Children With Intrauterine Exposure to Cocaine, Alcohol, Tobacco, and Marijuana (full - 2008) http://pediatrics.aappublications.org/cgi/reprint/121/4/741?maxtoshow=&hits=80&RESULTFORMAT=&f ulltext=marihuana&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT

Loss of Cannabinoid Receptor CB1 Induces Preterm Birth (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553193/?tool=pmcentrez
553

Medical marijuana: a surprising solution to severe morning sickness (news - 2008)

http://current.com/items/89174292_medical-marijuana-a-surprising-solution-to-severe-morning- sickness.htm

Maternal tobacco, cannabis and alcohol use during pregnancy and risk of adolescent psychotic symptoms in offspring. (full - 2009) http://bjp.rcpsych.org/cgi/content/full/195/4/294

Localisation and Function of the Endocannabinoid System in the Human Ovary (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640464/?tool=pmcentrez

Marijuana/ Cannabis use in Pregnancy – Dr. Melanie Dreher (article – 2009)

http://patients4medicalmarijuana.wordpress.com/2009/12/20/marijuana-cannabis-use-in-pregnancy-dr- melanie-dreher/

Cannabinoid/Endocannabinoid signaling impact on early pregnancy events. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/21104387

During pregnancy, recreational drug-using women stop taking ecstasy (3,4- methylenedioxy-N-methylamphetamine) and reduce alcohol consumption, but continue to smoke tobacco and cannabis: initial findings from the Development and Infancy Study. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19939863

Short communication: Urinary excretion of 11-nor-9-carboxy-Delta(9)- tetrahydrocannabinol in a pregnant woman following heavy, chronic cannabis use. (letter - 2009)

http://www.unboundmedicine.com/medline/ebm/record/20040136/abstract/Short_communication:_Urinary _excretion_of_11_nor_9_carboxy_Delta_9__tetrahydrocannabinol_in_a_pregnant_woman_following_hea vy_chronic_cannabis_use_

CLAIM #7: MARIJUANA USE DURING PREGNANCY HARMS THE FETUS (news - 2009) http://www.erowid.org/plants/cannabis/cannabis_myth7.shtml

Maternal Marijuana use not Associated with Psychotic Symptoms , but Alcohol is (news - 2009) http://ohiopatientsnetwork.org/index.php?option=com_content&view=article&id=85:marijuana-not- associated-with-psychotic-symptoms-but-alcohol-is&catid=3:newsflash

The Maternal Lifestyle Study: Sleep Problems in Children with Prenatal Substance Exposure (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917192/?tool=pubmed

Cannabinoids and Reproduction: A Lasting and Intriguing History (full – 2010)

http://www.mdpi.com/1424-8247/3/10/3275/pdf

A prospective study on intrauterine cannabis exposure and fetal blood flow. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20451334
554

Tocolytic Effect of Δ9-Tetrahydrocannabinol in Mice Model of Lipopolysaccharide— Induced Preterm Delivery: Role of Nitric Oxide (abst - 2010) http://rsx.sagepub.com/content/17/4/391.abstract

A common variation in the cannabinoid 1 receptor (CNR1) gene is associated with pre- eclampsia in the Central European population. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21129839

Characteristics of pregnant illicit drug users and associations between cannabis use and perinatal outcome in a population-based study (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20171023

Pregnant Women Smoking Pot Could Reduce Infant Mortality (news - 2010)

http://www.opposingviews.com/i/pregnant-women-smoking-pot-could-reduce-infant-mortality

Pregnant women turning to cannabis for morning sickness relief risk prosecution (news - 2010)

http://stash.norml.org/pregnant-wom...-for-morning-sickness-relief-risk-prosecution

Scientific Opinion on the safety of hemp (Cannabis genus) for use as animal feed (full – 2011) (deceptive title) http://www.hanf-info.ch/info/en/IMG/pdf/EIHA-11-05-31_EIHA-Statement_on_THC_in_feed.pdf

Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996668/?tool=pubmed

Prenatal tobacco, marijuana, stimulant, and opiate exposure: outcomes and practice implications. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188826/?tool=pubmed

Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137183/?tool=pubmed

Medical Marijuana: Can Pot Help Pregnant Women With Vomiting and Nausea? (article – 2011) http://patients4medicalmarijuana.wordpress.com/2011/01/13/pregnancy-and-medical-marijuana-can-pot- help-pregnant-women-with-vomiting-and-nausea/

Cannabinoid hyperemesis syndrome: an underreported entity causing nausea and vomiting of pregnancy. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21170540

PRIONS

Nonpsychoactive cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity (full - 2007) http://www.jneurosci.org/cgi/content/full/27/36/9537
555
 
Pages 556 - 560

Recent News: Marijuana (Cannabis) May Prevent Mad Cow Disease (news - 2007)

http://www.evilmamacow.org/marijuana-prevents-mad-cow-disease.php

Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease) (news - 2007) http://www.letfreedomgrow.com/articles/fr070916.htm

Pot Compound Protective Against ̳Mad Cow‘ Disease, Other Fatal Brain Disorders, Study Says (news - 2007) http://www.norml.org/index.cfm?Group_ID=7362

Pot smoking could stop Mad Cow Disease? (news - 2008)

http://chattahbox.com/curiosity/2008/12/06/pot-smoking-could-stop-mad-cow-disease/

Alteration of the Endocannabinoid System In Mouse Brain During Prion Disease.
(abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21195746/abstract/Alteration_of_the_Endocannabi noid_System_In_Mouse_Brain_During_Prion_Disease_

PROXIMAL MYOTONIC MYOPATHY / PROMM

Marijuana for the Management of Proximal Myotonic Myopathy (full - 2001)

http://www.jpsmjournal.com/article/S0885-3924(01)00252-4/fulltext

PRURITIS - chronic itch

Dronabinol in patients with intractable pruritus secondary to cholestatic liver disease. (abst - 2002)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=116

Preliminary observation with dronabinol in patients with intractable pruritus secondary to cholestatic liver disease. (abst – 2002) http://www.ncbi.nlm.nih.gov/pubmed/12190187

The cannabinoid agonist WIN 55, 212-2 increases nociception threshold in cholestatic rats: implications for the treatment of the pruritus of cholestasis. (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/13679241

Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin. (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/12835895

Pathogenesis and treatment of pruritus in patients with cholestasis (abst – 2003)

http://www.ncbi.nlm.nih.gov/pubmed/12664347
556

Treatment of the Pruritus of Cholestasis. (abst – 2004)

http://www.ncbi.nlm.nih.gov/pubmed/15527716

Efficacy and tolerance of the cream containing structured physiological lipids with endocannabinoids in the treatment of uremic pruritus: a preliminary study.
(abst - 2005)
http://www.ncbi.nlm.nih.gov/pubmed/16324422

Rational symptomatic therapy for chronic pruritus (abst – 2005)

http://www.ncbi.nlm.nih.gov/pubmed/16583225

Old drugs in new role: relieving chronic pruritus; Cannabinoid agonists, opioid receptor antagonists have attracted the attention of dermatologists (news - 2005) http://findarticles.com/p/articles/mi_hb4345/is_12_33/ai_n29239763/?tag=content;col1

Cream with endocannabinoids effective in the treatment of pruritus (news - 2005)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=207

Cream with endocannabinoids effective in the treatment of pruritus due to kidney disease (news - 2005) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=207

Neurophysiological, Neuroimmunological, and Neuroendocrine Basis of Pruritus (full - 2006) http://www.nature.com/jid/journal/v126/n8/full/5700231a.html

Frontiers in pruritus research: scratching the brain for more effective itch therapy
(full – 2006) http://www.jci.org/articles/view/28...ext]=&search[article_text]=cannabinoid&search[a uthors_text]=&search[fpage]=&search[title_text]=&search[volume]=

Topical cannabinoid agonists : An effective new possibility for treating chronic pruritus. (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=196

Adjuvant treatment of atopic eczema: assessment of an emollient containing N- palmitoylethanolamine (ATOPA study). (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18181976

Chronic pruritus: targets, mechanisms and future therapies. (abst - 2008)

http://www.ncbi.nlm.nih.gov/pubmed/19221635?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa nel.Pubmed_RVDocSum&ordinalpos=51

The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757311/?tool=pmcentrez

Endocannabinoid modulation of scratching response in an acute allergenic model: a new

prospective neural therapeutic target for pruritus. (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670585/?tool=pubmed
557

Cannabinoid system in the skin - a possible target for future therapies in dermatology. (full - 2009) http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0625.2009.00923.x/full

Cannabis: Potential treatment for skin disorders? (news - 2009)

http://www.examiner.com/x-17593-NORML-Examiner~y2009m8d29-Cannabis-Potential-treatment-for- skin-disorders

The Management of Chronic Pruritus in the Elderly (full – 2010)

http://www.skintherapyletter.com/2010/15.8/2.html

Is there a legitimate role for the therapeutic use of cannabinoids for symptom management in chronic kidney disease? (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21269798

CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21340468/abstract/CB1_receptors_mediate_rimon abant_induced_pruritic_responses_in_mice:_investigation_of_locus_of_action_

Endocannabinoid signaling and epidermal differentiation. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21628127

PSORIASIS

The Endocannabinoid System in Human Keratinocytes (full – 2003)

http://www.jbc.org/content/278/36/33896.full

Cannabinoids, loratadine and allopurinol as novel additions to the antipsoriatic ammunition. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/15857457

Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner (full – 2007) http://www.jbc.org/content/283/10/6005.full

Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17157480

Marijuana Skin Cream? (news - 2007)

http://www.drugfree.org/join-together/drugs/marijuana-skin-cream

The endocannabinoid system of the skin in health and disease: novel perspectives and

therapeutic opportunities (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757311/?tool=pmcentrez
558

Patent application title: PHARMACOLOGICAL TREATMENT OF PSORIASIS (full – 2010) http://www.faqs.org/patents/app/20080255224

Endocannabinoid signaling and epidermal differentiation. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21628127

QUITTING CANNABIS - also see ADDICTION and WITHDRAWAL

An Abstinence Syndrome Following Chronic Administration of Delta-9- terahydrocannabinol in Rhesus Monkeys. (abst – 1980) http://www.ncbi.nlm.nih.gov/pubmed/6255508

A 12-step Treatment Approach for Marijuana (Cannabis) Dependence.

(abst – 1989)
http://medical-journals.healia.com/doc/2687482/A-12-step-treatment-approach-for-marijuana-Cannabis- dependence

Psychotropic Analgesic Nitrous Oxide Prevents Craving After Withdrawal for Alcohol, Cannabis and Tobacco. (abst – 1994) http://www.ncbi.nlm.nih.gov/pubmed/7960461

Tobacco and Cannabis Smoking Cessation Can Lead to Intoxication with Clozapine or Olanzapine. (abst – 2002)

http://medical-journals.healia.com/doc/11981356/Tobacco-and-cannabis-smoking-cessation-can-lead-to- intoxication-with-clozapine-or-olanzapine

The Time Course and Significance of Cannabis Withdrawal. (abst – 2003)

http://medical-journals.healia.com/doc/12943018/The-time-course-and-significance-of-cannabis- withdrawal

Strategies for quitting among non-treatment-seeking marijuana smokers. (abst – 2005)

http://www.ncbi.nlm.nih.gov/pubmed/15804875

Aerobic Exercise Training Reduces Cannabis Craving and Use in Non-Treatment Seeking Cannabis-Dependent Adults (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050879/?tool=pmcentrez

Exercise can reduce cannabis use in persons who don't want to stop (news – 2011)

http://www.news-medical.net/news/20110304/Exercise-can-reduce-cannabis-use-in-persons-who-dont- want-to-stop.aspx
559

QUITTING OTHER DRUGS


The Use of Indian Hemp in the Treatment of Chronic Chloral and Chronic Opium Poisoning (1889) http://www.onlinepot.org/medical/Dr_Tods_PDFs/s3_2.pdf

Cannabis substitution . An adjunctive therapeutic tool in the treatment of alcoholism. (abst - 1970) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=86

Differential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats. (abst - 1975) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=1237925&dopt=abstract plus

Morphine-dependent rats: blockade of precipitated abstinence by tetrahydrocannabinol. (abst – 1975) http://www.ncbi.nlm.nih.gov/pubmed/1167428

Effect of some cannabinoids on naloxone-precipitated abstinence in morphine-dependent mice. (abst – 1976) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=826944&dopt=abstractp lus

Inhibition of naloxone-induced withdrawal in morphine dependent mice by 1-trans- delta9-tetrahydrocannabinol. (abst – 1976) http://www.ncbi.nlm.nih.gov/pubmed/944134

Time course of the effects of naturally occurring cannabinoids on morphine abstinence syndrome. (abst – 1978) http://www.ncbi.nlm.nih.gov/pubmed/564515

The quasi-morphine withdrawal syndrome: effect of cannabinol, cannabidiol and tetrahydrocannabinol. (abst - 1985) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=2994117&dopt=abstract plus

Marijuana use and treatment outcome among opioid-dependent patients. (abst – 1998)

http://www.ncbi.nlm.nih.gov/pubmed/9684388

Therapeutic use of cannabis by crack addicts in Brazil. (full - 1999)

http://science.iowamedicalmarijuana.org/pdfs/addiction/Labigalini Therapeutic Cannabis Crack %20Brazil%20J%20Psychoact%20Drugs%201999.pdf

Go clean with spliffs (news - 2001)

http://www.newscientist.com/article/mg17223123.800-go-clean-with-spliffs.html

Cannabinoids vs. Cocaine (news - 2001)

http://findarticles.com/p/articles/mi_hb4365/is_22_34/ai_n28879983/?tag=content;col1

Crack heads and roots daughters: The therapeutic use of cannabis in Jamaica (cocaine)

(abst - 2002)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=260
560
 
Pages 561 - 565

Does Cannabis Use Predict Poor Outcome for Heroin-Dependent Patients on Maintenance Treatment? A Review of Past Findings, and More Evidence Against (full – 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943839/

Modulation of oral morphine antinociceptive tolerance and naloxone-precipitated withdrawal signs by oral Delta 9-tetrahydrocannabinol. (full – 2003) http://jpet.aspetjournals.org/content/305/3/812.long

Does Cannabis Use Predict Poor Outcome for Heroin-dependent Patients on Maintenance Treatment? Past Findings and More Evidence Against. (abst – 2003) http://medical-journals.healia.com/doc/12603227/Does-cannabis-use-predict-poor-outcome-for-heroin- dependent-patients-on-maintenance-treatment-Past-findings-and-more-evidence-against

Cannabis as a Substitute for Alcohol (news - 2003)

http://ccrmg.org/journal/03sum/substitutealcohol.html

Cannabis Abuse is Not a Risk Factor for Treatment Outcome in Methadone Maintenance Treatment: a 1-year Prospective Study in an Israeli Clinic. (abst – 2004) http://www.ncbi.nlm.nih.gov/pubmed/14731193

Delta9-tetrahydrocannabinol decreases somatic and motivational manifestations of nicotine withdrawal in mice. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15548217?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pub med_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol- Induced Neurotoxicity (full - 2005) http://jpet.aspetjournals.org/content/314/2/780.full

Role of cannabinoid receptors in alcohol abuse (news - 2005)

http://www.medicalnewstoday.com/articles/30338.php

Subchronic cannabinoid agonist (WIN 55,212-2) treatment during cocaine abstinence alters subsequent cocaine seeking behavior. (full - 2007) http://www.nature.com/npp/journal/v32/n11/abs/1301365a.html

Chronologically overlapping occurrences of nicotine-induced anxiety- and depression- related behavioral symptoms: effects of anxiolytic and cannabinoid drugs (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075518/?tool=pubmed

Modulation of the endocannabinoid system: therapeutic potential against cocaine dependence. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134985/?tool=pubmed

Inhibition of anandamide hydrolysis by URB597 reverses abuse-related behavioral and

neurochemical effects of nicotine in rats. (abst – 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663803/?tool=pubmed
561

Curing Addiction With Cannabis Medicines? (news - 2008)

http://www.sciencedaily.com/releases/2008/03/080307110348.htm

Cannabis-based Drugs can help you quit Smoking (news - 2008)

http://www.healthjockey.com/2008/03/11/cannabis-based-drugs-can-help-you-quit-smoking/

Cannabidiol, a Nonpsychotropic Component of Cannabis, Inhibits Cue-Induced Heroin Seeking and Normalizes Discrete Mesolimbic Neuronal Disturbances (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829756/?tool=pmcentrez

Intermittent marijuana use is associated with improved retention in naltrexone treatment for opiate-dependence. (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753886/?tool=pubmed

Cannabis as a substitute for alcohol and other drugs. (full - 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795734/?tool=pmcentrez

Effects of the cannabinoid CB1 receptor antagonist AM 251 on the reinstatement of nicotine-conditioned place preference by drug priming in rats. (full- 2009) http://www.if-pan.krakow.pl/pjp/pdf/2009/2_304.pdf

Interaction of the cannabinoid and opioid systems in the modulation of nociception.
(abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19367508?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa nel.Pubmed_RVDocSum&ordinalpos=34

Is Cannabis the Answer to Booze Britain's Problems? (news - 2009)

http://www.sciencedaily.com/releases/2009/11/091130192917.htm

Cannabis as a substitute for heavy alcohol usage? (news - 2009)

http://www.news-medical.net/news/20091201/Cannabis-as-a-substitute-for-heavy-alcohol-usage.aspx

Medical marijuana users in substance abuse treatment. (full - 2010)

http://www.harmreductionjournal.com/content/pdf/1477-7517-7-3.pdf

Attenuation of morphine antinociceptive tolerance by a CB(1) receptor agonist and an NMDA receptor antagonist: Interactive effects. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813317/?tool=pubmed

Oaklanders Quitting Oxycontin with Cannabis (news - 2010)

http://www.eastbayexpress.com/LegalizationNation/archives/2010/04/22/oaklanders-quitting-oxycontin- with-cannabis

Marijuana To Control Alcohol Abuse (news - 2010)

http://psychcentral.com/news/2009/12/01/marijuana-to-control-alcohol-abuse/9863.html

Marijuana could be an ―exit drug‖ (news - 2010)

http://newmexicoindependent.com/52915/marijuana-could-be-an-exit-drug
562

Study shows direct cellular interaction between endocannabinoids and alcohol in the brain (news - 2010) http://www.news-medical.net/news/20100513/Study-shows-direct-cellular-interaction-between- endocannabinoids-and-alcohol-in-the-brain.aspx

Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227620/?tool=pubmed

The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats
(abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21557729/abstract/The_anandamide_transport_inh ibitor_AM404_reduces_the_rewarding_effects_of_nicotine_and_nicotine_induced_dopamine_elevations_i n_the_nucleus_accumbens_shell_in_rats_

Brain cannabinoid CB2 receptors modulate cocaine's actions in mice (abst – 2011)

http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.2874.html

Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21886913

The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats.
(abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21557729

Study: Marijuana compound helps mitigate cocaine addiction in mice (news – 2011)

http://www.rawstory.com/rs/2011/07/26/study-marijuana-compound-helps-mitigate-cocaine-addiction-in- mice/

Stimulation Of Marijuana Receptor Reduces Cocaine Consumption, Study Says (news – 2011) http://norml.org/index.cfm?Group_ID=8639

Why Medical Marijuana Laws Reduce Traffic Deaths (news - 2011)

http://healthland.time.com/2011/12/02/why-medical-marijuana-laws-reduce-traffic-deaths/

Medical marijuana turns former soldier's life around (news – 2011)

http://www.examiner.com/cannabis-culture-in-phoenix/medical-marijuana-turns-former-soldier-s-life- around

RADIATION-INDUCED NAUSEA

Randomised Clinical Trial of Levonantradol and Chlorpromazine in the Prevention of

Radiotherapy-induced Vomiting. (abst - 1982)

http://www.ncbi.nlm.nih.gov/pubmed/6754212
563

A double-blind randomised cross-over comparison of nabilone and metoclopramide in the control of radiation-induced nausea. (abst - 1987) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=130

Receptor mechanism and antiemetic activity of structurally-diverse cannabinoids against radiation-induced emesis in the least shrew. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949344/?tool=pmcentrez

RADIATION SICKNESS

Regulation of hematopoietic stem cell trafficking and mobilization by the endocannabinoid system. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22074629

REFLEX SYMPATHETIC DYSTROPHY

DEA Raids Aurora Medical Marijuana User (news/ anecdotal – 2004)

http://www.freecolorado.com/2004/07/danaraid.html

Medi-Cal pays pot-related expenses (news – 2007)

http://www.pressdemocrat.com/article/20070707/NEWS/707070324?Title=Medi-Cal-pays-pot-related- expenses

RSD Patient Gets Relief Through Medical Marijuana (news - 2009)

http://www.disaboom.com/reflex-sympathetic-dystrophy-syndrome-rsd/rsd-patient-gets-relief-through- medical-marijuana

An Opiate Controlled Population by Ryan Harshbarger (news/ anecdotal- 2009)

http://www.bakedlife.com/2009/09/opiate-controlled-population-by-ryan.html

Control of bone remodeling by nervous system. Nervous system and bone

http://www.ncbi.nlm.nih.gov/pubmed/21123931

RESTLESS LEG SYNDROME

Marijuana & Restless Leg Syndrome (news - no date)

http://www.ehow.com/about_5380787_marijuana-restless-leg-syndrome.html

Restless Leg Syndrome: Medical Marijuana Patients‘ Say it Works (news - 2007)

http://www.salem-news.com/articles/august182007/leveque_med_restless_81807.php

(abst – 2010)
564

Restless Leg Syndrome (news/anecdotal- 2007)

http://medicalcannabisawareness.myblogsite.com/entry34.html#body

RETINITIS PIGMENTOSA

Smoking dope restored my sight (news - 1998) http://news.bbc.co.uk/2/hi/health/212301.stm

Cannabis improves night vision: a case study of dark adaptometry and scotopic sensitivity in kif smokers of the Rif mountains of northern Morocco (full - 2004) http://science.iowamedicalmarijuana.org/pdfs/misc/Russo et al. Cannabis Night Vision %20JEP%202004.pdf

When spliff gets in your eyes... (news – 2004)

http://www.guardian.co.uk/science/2004/jul/07/sciencenews.research

RIMONABANT/ ACOMPLIA/ SR141716/ SR1 – a CB1 & CB2 antagonist
The cannabinoid CB1 receptor antagonist SR 141716A reverses the antiemetic and motor

depressant actions of WIN 55, 212-2 (abst – 2001) http://pharmgkb.org/pmid/11698062

Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon (full – 2003) http://ajpgi.physiology.org/content/286/1/G110.full?sid=fc6948f0-78cf-405c-981b-afaa05ee417c

Overeating, Alcohol and Sucrose Consumption Decrease in Cb1 Receptor Deleted Mice. (abst – 2004) http://medical-journals.healia.com/doc/12770700/Overeating-alcohol-and-sucrose-consumption-decrease- in-CB1-receptor-deleted-mice

Ethanol Induces Higher Bec in Cb1 Cannabinoid Receptor Knockout Mice While Decreasing Ethanol Preference. (full – 2005) http://alcalc.oxfordjournals.org/content/40/1/54.long

Activation of the Peripheral Endocannabinoid System in Human Obesity (full - 2005)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228268/?tool=pmcentrez

Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html
565
 
Pages 566 - -570

The Cannabinoid Cb1 Receptor Antagonist Rimonabant Attenuates the Hypotensive Effect of Smoked Marijuana in Male Smokers. (full – 2006) http://www.ahjonline.com/article/S0002-8703(05)01013-6/fulltext

Weight Control in Individuals With Diabetes (full - 2006)

http://care.diabetesjournals.org/content/29/12/2749.full?maxtoshow=&hits=80&RESULTFORMAT=&full text=cannabis&searchid=1&FIRSTINDEX=2000&resourcetype=HWCIT

Anxiolytic-like properties of the anandamide transport inhibitor AM404. (abst – 2006)

http://www.ncbi.nlm.nih.gov/pubmed/16541083

Lack of tolerance to the suppressing effect of rimonabant on chocolate intake in rats. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16491428

Big Pharma's Strange Holy Grail: Cannabis Without Euphoria? (news - 2006)

http://www.counterpunch.org/gardner07082006.html

Cross-sensitization and cross-tolerance between exogenous cannabinoid antinociception and endocannabinoid-mediated stress-induced analgesia (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771679/?tool=pubmed

Single and multiple doses of rimonabant antagonize acute effects of smoked cannabis in male cannabis users. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689519/?tool=pubmed

Rimonabant (SR141716) exerts anti-proliferative and immunomodulatory effects in human peripheral blood mononuclear cells ( full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267266/?tool=pmcentrez

Cannabinoid CB1 receptors in the paraventricular nucleus and central control of penile erection: immunocytochemistry, autoradiography and behavioral studies (abst – 2007) http://pharmgkb.org/pmid/17507169

Report in Lancet Links Rimonabant to 'Severe Adverse Psychiatric Events' (news - 2007) http://www.rimonabantreport.com/News/news-111707.htm

Delay in Approval of Diet Pill Rimonabant in U.S. Tied to 'Psychiatric Adverse Effects' (news - 2007) http://www.rimonabantreport.com/News/news-061107.htm

Study: Rimonabant Weight Loss Modest and Side-Effects Are Concern

http://www.rimonabantreport.com/News/news-111507.htm

European watchdog warns about dangers of Acomplia (news - 2007)

http://www.news-medical.net/news/2007/07/21/27891.aspx

Three Long-Term Diet Pills Show Poor Performance, Study Suggests

http://www.sciencedaily.com/releases/2007/11/071116094804.htm

(news - 2007)

(news - 2007)
566

FDA Advisory Panel Rejects Obesity Drug (news - 2007)

http://firstwatch.jwatch.org/cgi/content/full/2007/615/2?maxtoshow=&hits=80&RESULTFORMAT=&full text=cannabinoid&searchid=1&FIRSTINDEX=2800&resourcetype=HWCIT

Study: Acomplia (Rimonabant) May Increase Risk of Colorectal Cancer

http://www.rimonabantreport.com/News/news-080208.htm

Rimonabant doesn't reduce heart risk (news - 2008)

http://www.healthandage.com/Rimonabant-doesnt-reduce-heart-risk

Caution Urged With New Anti-Obesity Drug In Kids (news - 2008)

http://www.sciencedaily.com/releases/2008/05/080507133326.htm

(news - 2008)
Regulators Call for Withdrawal of Acomplia (Rimonabant) from European Market (news - 2008) http://www.rimonabantreport.com/News/news-102408.htm

The psychiatric side-effects of rimonabant. (full – 2009)

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516- 44462009000200012&lng=en&nrm=iso&tlng=en

The endocanabinnoid system and diabetes - critical analyses of studies conducted with rimonabant (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770455/?tool=pmcentrez

Cannabinoids for clinicians: the rise and fall of the cannabinoid antagonists (full - 2009)

http://www.eje- online.org/cgi/content/full/161/5/655?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid &searchid=1&FIRSTINDEX=160&resourcetype=HWCIT

Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765124/?tool=pubmed

Systematic review and meta-analysis on the adverse events of rimonabant treatment: Considerations for its potential use in hepatology (full - 2009) http://www.biomedcentral.com/1471-230X/9/75
Endocannabinoids and cardiovascular prevention: real progress?

http://www.pagepress.org/journals/index.php/hi/article/view/1162

Therapeutical use of the cannabinoids in psychiatry (full – 2010)

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516- 44462010000500009&lng=en&nrm=iso&tlng=en

(abst - 2009)
Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes? (full – 2010) http://www.jci.org/articles/view/44...ext]=&search[article_text]=cannabinoid&search[a uthors_text]=&search[fpage]=&search[title_text]=&search[volume]=
567

The Effects of Rimonabant on Brown Adipose Tissue in Rat: Implications for Energy Expenditure (full - 2010) http://www.nature.com/oby/journal/v17/n2/full/oby2008509a.html

The Endocannabinoid System Tonically Regulates Inhibitory Transmission and Depresses the Effect of Ethanol in Central Amygdala (abst - 2010) http://www.nature.com/npp/journal/v35/n9/abs/npp201070a.html

Rimonabant-induced Delta9-tetrahydrocannabinol withdrawal in rhesus monkeys: discriminative stimulus effects and other withdrawal signs. (abst – 2010) http://www.unboundmedicine.com/medline/ebm/record/20375197/abstract/Rimonabant_induced_Delta9_te trahydrocannabinol_withdrawal_in_rhesus_monkeys:_discriminative_stimulus_effects_and_other_withdra wal_signs_

Anxiety-like effects of SR141716-precipitated delta9-tetrahydrocannabinol withdrawal in mice in the elevated plus-maze. (abst – 2010) http://www.unboundmedicine.com/medline/ebm/record/20363293/abstract/Anxiety_like_effects_of_SR141 716_precipitated_delta9_tetrahydrocannabinol_withdrawal_in_mice_in_the_elevated_plus_maze_

Reduced neural response to reward following 7 days treatment with the cannabinoid CB1 antagonist rimonabant in healthy volunteers (abst – 2010) http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=7873271&fulltextType=RA&f ileId=S1461145710000453

Risk of suicide spurs rimonabant trial to end. (news – 2010)

http://www.thefreelibrary.com/Risk+of+suicide+spurs+rimonabant+trial+to+end.-a0238838571

Endocannabinoid system protects against cryptogenic seizures. (full – 2011)

http://www.if-pan.krakow.pl/pjp/pdf/2011/1_165.pdf

Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/20965292

The identification of rimonabant polymorphs, sibutramine and analogues of both in counterfeit Acomplia bought on the internet. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/20828968

Pro-epileptic effects of the cannabinoid receptor antagonist SR141716 in a model of audiogenic epilepsy. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21733658

Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21886913

Antagonist-elicited cannabis withdrawal in humans. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21869692

Intracellular Cannabinoid Type 1 (CB1) Receptors Are Activated by Anandamide

(abst – 2011)

http://www.jbc.org/content/286/33/29166.abstract?sid=2c3b88ec-b6e6-4245-a171-2e24c17b5e8b
568

Effects of the cannabinoid antagonist SR 141716 on sexual and motor behavior in receptive female rats. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21848907

CB(1) -independent mechanisms of Δ(9) -THCV, AM251 and SR141716 (rimonabant). (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21740450

CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21340468/abstract/CB1_receptors_mediate_rimon abant_induced_pruritic_responses_in_mice:_investigation_of_locus_of_action_

Chronic Δ9-tetrahydrocannabinol treatment in rhesus monkeys: differential tolerance and cross-tolerance among cannabinoids. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21091643/abstract/Chronic_%CE%94%E2%81%B 9_tetrahydrocannabinol_treatment_in_rhesus_monkeys:_differential_tolerance_and_cross_tolerance_amon g_cannabinoids_

CB1 cannabinoid receptor mediates glucocorticoid effects on hormone secretion induced by volume and osmotic changes. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22211674

Smoking marijuana not linked to obesity: study (news – 2011)

http://health.yahoo.net/news/s/nm/us_marijuana_obesity

The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: Evidence from postmortem human brain. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22093909

Rimonabant reduces the essential value of food in the genetically obese Zucker rat: An exponential demand analysis. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22019829

Extinction learning of rewards in the rat: is there a role for CB1 receptors? (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21519986

R(+)-METHANANANDAMIDE – synthetic, Anandamide analog
Cannabinoids might reduce spasticity in multiple sclerosis (full - 2000)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1117698/?tool=pmcentrez

Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism. (abst - 2002) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=12428277&dopt=abstrac tplus
569

CANNABINOIDS ALTER RECOGNITION MEMORY IN RATS (full – 2003)

http://www.if-pan.krakow.pl/pjp/pdf/2003/5_903.pdf

Up-Regulation of Cyclooxygenase-2 Expression Is Involved in R(_)-Methanandamide- Induced Apoptotic Death of Human Neuroglioma Cells (full - 2004) http://science.iowamedicalmarijuana.org/pdfs/cancer/Hinz 2004.pdf

Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma (full - 2006) http://molpharm.aspetjournals.org/content/70/5/1612.full

R(+)-methanandamide elicits a cyclooxygenase-2-dependent mitochondrial apoptosis signaling pathway in human neuroglioma cells. (abst – 2006) http://www.springerlink.com/content/l403431l1728x733/

Loss of cannabinoid receptor 1 accelerates intestinal tumor growth (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561258/?tool=pubmed

Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)- Methanandamide and JWH-015: Involvement of CB2 (full - 2009) http://www.nature.com/bjc/journal/v101/n6/full/6605248a.html

Potentiation of cannabinoid-induced cytotoxicity in mantle cell lymphoma through modulation of ceramide metabolism. (full - 2009) http://mcr.aacrjournals.org/content/7/7/1086.long

Cannabinoid Receptor Activation Protects Coronary Endothelium Against Reperfusion Induced Intercellular Gap Formation in a Cellular Model of Ischemia and Reperfusion (abst - 2009)

http://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S1072- c?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=720& resourcetype=HWCIT

The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19908944

R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19015962

Cannabis chemicals may help fight prostate cancer (news - 2010)

http://www.abbotsfordtimes.com/entertainment/movie- guide/Cannabis+chemicals+help+fight+prostate+cancer/1908592/story.html?id=1908592#Comments

Pharmacological elevation of anandamide impairs short-term memory by altering the

neurophysiology in the hippocampus. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21767554
570
 
Pages 571 - 575

Effects of Cannabinoid Agonists on Sheep Sphincter of Oddi in vitro. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21921665

RWJ 400065 - synthetic cannabinoid

Control of spasticity in a multiple sclerosis model is mediated by CB1, not CB2, cannabinoid receptors. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189718/?tool=pubmed

SAFETY AS A MEDICINE

THE RELATIVE ACTIVITY OF VARIOUS PURIFIED PRODUCTS OBTAINED FROM AMERICAN GROWN HASHISH (abst - 1938) http://jpet.aspetjournals.org/content/62/2/239.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabis&searchid=1&FIRSTINDEX=640&resourcetype=HWCIT

STUDIES ON THE PHARMACOLOGY AND ACUTE TOXICITY OF COMPOUNDS WITH MARIHUANA ACTIVITY (abst - 1946) http://jpet.aspetjournals.org/content/88/2/154.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Allergy to Marihuana (abst - 1971)

http://www.annals.org/content/75/4/571.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=ca nnabis&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT

Cognition and Long-Term Use of Ganja (Cannabis) (full - 1981)

http://www.druglibrary.org/schaffer/hemp/medical/cognition.htm
Excerpt from the Merck Manual (excerpt- 1987) http://www.ukcia.org/research/merck.htm

THREE THINGS MARIJUANA DOESN'T DO (news - 1992)

http://www.ukcia.org/research/mjfaq2.php

Health care use by frequent marijuana smokers who do not smoke tobacco.
(full - 1993) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1311782/pdf/westjmed00082-0044.pdf

Proven: Cannabis is safe medicine (news - 1996)

http://www.ukcia.org/research/safe-medicine.htm

Two hundred and thirteen cases of marijuana toxicoses in dogs. (abst – 2002)

http://www.ncbi.nlm.nih.gov/pubmed?term=Caroline W. Donaldson
571

The good and the bad effects of (−) trans-delta-9-tetrahydrocannabinol (Δ9-THC) on humans (abst - 2004) http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCS-4CSG2C4- 2&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlV ersion=0&_userid=10&md5=99df29b0ce94c395c01f5aad8825d28b

Adverse effects of medical cannabinoids: a systematic review (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413308/

Merck Manual - Marijuana (Cannabis) (excerpt - 2008)

http://www.merckmanuals.com/professional/sec23/ch352/ch352i.html?qt=marijuana&alt=sh

How Safe Are Medical Cannabinoids? (news – 2008)

http://www.medicalnewstoday.com/releases/111442.php

Claims Linking Health Problems And The Strength Of Cannabis May Be Exaggerated (news - 2008)
http://www.sciencedaily.com/releases/2008/06/080617125751.htm

Medical use of cannabinoids does not cause an increase in serious adverse health effects (news - 2008) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=272

Report: Marijuana Less Harmful than Alcohol or Tobacco (news - 2008)

http://www.drugfree.org/join-together/other/report-marijuana-less

Medicines derived from cannabis: A review of adverse events (news - 2008)

http://www.news-medical.net/news/2008/06/16/39254.aspx

Alcohol and cannabis use as risk factors for injury - a case-crossover analysis in a Swiss hospital emergency department (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654886/?tool=pubmed

Deaths from Marijuana v. 17 FDA-Approved Drugs (Jan. 1, 1997 to June 30, 2005) (report - 2009) http://medicalmarijuana.procon.org/view.resource.php?resourceID=145

Harms associated with psychoactive substances: findings of the UKNational Drug Survey (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19939875/full_citation/Harms_associated_with_ps ychoactive_substances:_findings_of_the_UK_National_Drug_Survey_

Health Risks of Marijuana Still Not Nailed Down (news - 2009)

http://www.medpagetoday.com/Psychiatry/Addictions/16456

Four percent of adults worldwide using cannabis (news – 2009)

http://www.independent.co.uk/life-s...health-news/four-percent-of-adults-worldwide- using-cannabis-1804190.html
572

Marijuana-Related Health Costs Minimal Compared To Those Of Alcohol, Tobacco (news - 2009) http://www.norml.org/index.cfm?Group_ID=8022

The FDA has written documentation that patients can overdose on Marinol and that it can be lethal (news - 2009) http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2009m10d23-The-FDA- has-written-documentation-that-patients-can-overdose-on-Marinol-and-that-it-can-be-lethal

Information for Health Care Professionals (revised) - Overdose/Toxicity (Health Canada) (full - 2010) http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/index-eng.php#a9_0

Harms associated with psychoactive substances: findings of the UK National Drug Survey (abst - 2010) http://jop.sagepub.com/cgi/content/abstract/24/2/147?rss=1

An index of fatal toxicity for drugs of misuse. (full - 2010)

http://www.scribd.com/doc/41349905/Alcohol-Lancet-2010

Alcohol 'Most Harmful Drug', According to Multicriteria Analysis
(news - 2010) http://www.sciencedaily.com/releases/2010/11/101101162138.htm

Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent. (abst- 2011)

http://www.unboundmedicine.com/medline/ebm/record/22129319/abstract/Safety_and_Side_Effects_of_C annabidiol_a_Cannabis_sativa_Constituent_

Medical marijuana not a threat to workplace safety, study finds (news – 2011)

http://washingtonindependent.com/11...-not-a-threat-to-workplace-safety-study-finds

Is Pot Good For You? (news – 2011)

http://www.time.com/time/magazine/article/0,9171,1003570,00.html

Prescribing Cannabis for Harm Reduction. (full – 2012)

http://www.harmreductionjournal.com/content/pdf/1477-7517-9-1.pdf

SAFETY- ADULTERANTS/ CONTAMINANTS

Paraquat goes to pot. (full - 1978) http://chestjournal.chestpubs.org/content/74/4/358.long

Paraquat and marihuana. Assessing the hazard. (full - 1978)

http://chestjournal.chestpubs.org/content/74/4/357.long
(abst – 1977) An effect of paraquat on the lungs of rabbits. Its implications in smoking contaminated

Examination of fungal growth and aflatoxin production on marihuana.

http://www.ncbi.nlm.nih.gov/pubmed/414138
marihuana. (full - 1978) http://chestjournal.chestpubs.org/content/74/4/418.long
573

Detection and analysis of paraquat in confiscated marijuana samples. (abst – 1978)

http://www.ncbi.nlm.nih.gov/pubmed/258606

Allergic bronchopulmonary aspergillosis associated with smoking moldy marihuana. (full - 1978) http://chestjournal.chestpubs.org/content/73/6/871.long

Paraquat and marijuana: epidemiologic risk assessment. (full -1983)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1650884&tool=pmcentrez

Marijuana smoking and fungal sensitization. (abst - 1983)

http://www.ncbi.nlm.nih.gov/pubmed/6833678

Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient. (full - 1988) http://chestjournal.chestpubs.org/content/94/2/432.long

Microbiological contaminants of marijuana (full - 1994)

http://www.hempfood.com/IHA/iha01205.html

Successfully treated invasive pulmonary aspergillosis associated with smoking marijuana in a renal transplant recipient. (abst - 1996) http://www.ncbi.nlm.nih.gov/pubmed/8685958

Dust in the wind: the growing use of embalming fluid among youth in Hartford, CT. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/16040367

When the drug of choice is a drug of confusion: embalming fluid use in inner city Hartford, CT. (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/16275635

Beliefs and social norms about cigarettes or marijuana sticks laced with embalming fluid and phencyclidine (PCP): why youth use "fry". (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/15830737

An evaluation of the quality of medicinal grade cannabis in the Netherlands (full - 2006) http://www.cannabis-med.org/english/journal/en_2006_01_1.pdf

Adulteration of cannabis with tobacco, calamus, and other cholinergic compounds (full - 2008) http://www.cannabis-med.org/english/journal/en_2008_04_2.pdf

Invasive Pulmonary Aspergillosis Associated With Marijuana Use in a Man With Colorectal Cancer (full - 2008) http://jco.ascopubs.org/cgi/content/full/26/13/2214?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabis&searchid=1&FIRSTINDEX=3520&resourcetype=HWCIT

The use of fry (embalming fluid and PCP-laced cigarettes or marijuana sticks) among crack cocaine smokers (abst - 2008) http://www.unboundmedicine.com/medline/ebm/record/19157045/abstract/The_use_of_fry__embalming_f luid_and_PCP_laced_cigarettes_or_marijuana_sticks__among_crack_cocaine_smokers_
574

Ammonia release from heated 'street' cannabis leaf and its potential toxic effects on cannabis users. (abst - 2008) http://www.unboundmedicine.com/medline/ebm/record/18705690/abstract/Ammonia_release_from_heated _%27street%27_cannabis_leaf_and_its_potential_toxic_effects_on_cannabis_users_

Neuropsychological effects of formaldehyde use. (abst - 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18720671

Cannabis potency and contamination: a review of the literature. (abst - 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18494838

Lead poisoning due to adulterated marijuana in Leipzig. (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696942/?tool=pmcentrez

Smoke Pot, Get Lead Poisoning? (Germany/Europe) (news - 2008)

http://www.webmd.com/news/20080409/smoke-pot-get-lead-poisoning

Respiratory consequences of inhalation of adulterated cannabis (abst – 2009)
http://www.ncbi.nlm.nih.gov/pubmed/19543175

Medical marijuana tested for toxins and impurities (news - 2010)

http://www.wmbfnews.com/Global/story.asp?S=12340335

Too many mouldy joints - marijuana and chronic pulmonary aspergillosis.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103256/?tool=pubmed

SATIVEX / NABIXIMOLS - a cannabis extract spray
(full – 2011)

Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (full - 2005)

http://rheumatology.oxfordjournals.org/cgi/content/full/45/1/50
Sativex: Fact Sheet (full - 2005) http://www.bayer.ca/files/sativex_fs_fd_091289_e.pdf

Sativex: Health Care Professional letter (letter - 2005)

http://www.bayer.ca/files/sativex_dhcpl_lapds_091289_e.pdf

Sativex produced significant improvements in a subjective measure of spasticity (abst - 2005) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=170

Cannabis-based medicinal extract (Sativex) produced significant improvements in a subjective measure of spasticity which were maintained on long-term treatment with no evidence of tolerance. (abst - 2005) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=170
575
 
Pages 576 - 580

Conditional okay for cannabis prescription drug (news - 2005)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1150250&tool=pmcentrez

Cannabis-Based Drug Relieves Arthritis Pain (news - 2005)

http://www.medpagetoday.com/Rheumatology/Arthritis/2097

Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (full - 2006) http://rheumatology.oxfordjournals.org/cgi/content/full/45/1/50?maxtoshow=&hitqs=80&RESULTFORM AT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=2240&resourcetype=HWCIT

The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (letter - 2006) http://rheumatology.oxfordjournals.org/cgi/content/full/45/6/781

Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/17086911

Randomised controlled study of cannabis-based medicine (Sativex®) in patients suffering from multiple sclerosis associated detrusor overactivity (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=168

Sativex® in patients with symptoms of spasticity due to multiple sclerosis (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=169

SAFETY AND TOLERABILITY OF LONG-TERM TREATMENT WITH A CANNABIS-BASED MEDICINE (SATIVEX) IN PATIENTS WITH RHEUMATOID ARTHRITIS (abst - 2006)

http://eular.bmj.com/cgi/content/abstract/65/Suppl_2/498- a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1840 &resourcetype=HWCIT

Combined cannabinoid therapy via an oromucosal spray (abst – 2006)

http://journals.prous.com/journals/servlet/xmlxsl/pk_journals.xml_summaryn_pr?p_JournalId=4&p_RefId =1021517

Sativex showed positive effects in 65 per cent of patients with chronic diseases (news - 2006) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=230#4

Sativex: Fact Sheet (full - 2007)

http://www.bayer.ca/files/sativex_fs_fd_109461_e _GW_.pdf

Sativex: Health Care Professional letter (letter - 2007)

http://www.bayer.ca/files/sativex_dhcpl_lapds_109461_e _GW_-2.pdf
576

Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial. (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/18035205

Cannabis; adverse effects from an oromucosal spray. (abst - 2007)

http://www.nature.com/bdj/journal/v203/n6/abs/bdj.2007.749.html

Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex, a cannabis- based medicine. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17712817

Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17868014

Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17997224

Cannabinoids Associated With "More Restful Sleep," Study Says

http://www.illinoisnorml.org/content/view/648/27/

Sativex: Drug Monograph (monograph - 2008)

http://www.bayer.ca/files/SATIVEX-PM-ENG-18DEC2008-119950.pdf

Sativex: Consumer Information (full - 2008)

http://www.bayer.ca/files/SATIVEX-PM-ENG-PT3-18DEC2008-119950.pdf

(news - 2007)

Cannabinoids in the management of difficult to treat pain (full - 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503660/?tool=pmcentrez

Emerging strategies for exploiting cannabinoid receptor agonists as medicines. (full – 2009)
http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2008.00048.x/full

Summary of Product Characteristics- Sativex Oralmucosal Spray (full – 2010)

http://www.gwpharm.com/uploads/spc-doc.pdf

Meta-analysis of the efficacy and safety of Sativex (nabiximols), on spasticity in people with multiple sclerosis (abst - 2010) http://msj.sagepub.com/cgi/content/abstract/16/6/707?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabis&searchid=1&FIRSTINDEX=0&sortspec=date&resourcetype=HWCIT

Randomized controlled trial of Sativex to treat detrusor overactivity in multiple sclerosis. (abst – 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=314

Abuse potential and psychoactive effects of δ-9-tetrahydrocannabinol and cannabidiol

oromucosal spray (Sativex), a new cannabinoid medicine. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21542664
577

Subjective and physiological effects after controlled Sativex and oral THC administration. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21289620

Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21674569

A randomized, double-blind, placebo-controlled, crossover study to evaluate the subjective abuse potential and cognitive effects of nabiximols oromucosal spray in subjects with a history of recreational cannabis use. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21671456

A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex(®) ), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis. (abst – 2011) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=322

THC and CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis. (abst - 2011) http://www.unboundmedicine.com/medline/ebm/record/21456949/abstract/THC_and_CBD_oromucosal_s pray__Sativex%C2%AE__in_the_management_of_spasticity_associated_with_multiple_sclerosis_

Plasma cannabinoid pharmacokinetics following controlled oral delta9- tetrahydrocannabinol and oromucosal cannabis extract administration (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21078841/abstract/Plasma_cannabinoid_pharmaco kinetics_following_controlled_oral_delta9_tetrahydrocannabinol_and_oromucosal_cannabis_extract_admi nistration_

Is Pot Good For You? (news – 2011)

http://www.time.com/time/magazine/article/0,9171,1003570,00.html

SCHIZOPHRENIA/ MENTAL DISORDERS

radical notion (letter - 1974)

http://schizophreniabulletin.oxfordjournals.org/cgi/reprint/1/11/16- a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=1040&res ourcetype=HWCIT

Study Shows Long Term Marijuana Users Healthy (news - 1994)

http://www.erowid.org/plants/cannabis/cannabis_science3.shtml

Association study of a cannabinoid receptor gene (CNR1) polymorphism and schizophrenia (abst – 2000) http://pharmgkb.org/pmid/11204352
578

Are Cannabinoid Receptor Knockout Mice Animal Models for Schizophrenia?
(abst -2000) http://www.medical-hypotheses.com/article/S0306-9877(00)91261-1/abstract

Cannabis Use is Not Associated with the Development of Psychosis in an 'ultra' High-risk Group. (abst – 2002) http://www.ncbi.nlm.nih.gov/pubmed/12406123

Tobacco and Cannabis Smoking Cessation Can Lead to Intoxication with Clozapine or Olanzapine. (abst – 2002)

http://medical-journals.healia.com/doc/11981356/Tobacco-and-cannabis-smoking-cessation-can-lead-to- intoxication-with-clozapine-or-olanzapine

Recipe For Trouble (anecdotal/ news - 2002)

http://www.cbsnews.com/stories/2002/03/05/48hours/main503022.shtml

Cannabis may treat psychiatric disorders (news - 2002)

http://findarticles.com/p/articles/mi_hb5255/is_2002_August_5/ai_n28936175/?tag=content;col1

Cannabis and the brain. (full - 2003)

http://brain.oxfordjournals.org/cgi/content/full/126/6/1252

Haloperidol, but not clozapine, produces dramatic catalepsy in delta9-THC-treated rats: possible clinical implications. (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574061/?tool=pubmed

Cannabis as a psychotropic medication (letter - 2004)

http://bjp.rcpsych.org/cgi/content/full/185/1/78

Lower Negative Symptom Scores Among Cannabis-dependent Patients with Schizophrenia-spectrum Disorders: Preliminary Evidence from an African American First-episode Sample. (abst – 2004) http://www.schres-journal.com/article/S0920-9964(04)00035-0/abstract

Aetiology - Review: current evidence does not show a strong causal relation between the use of cannabis in young people and psychosocial harm (abst - 2004) http://www.library.nhs.uk/mentalHealth/ViewResource.aspx?resID=224106&tabID=289

How our brains fend off madness, we produce a cannabis like substance (news – 2004)

http://www.medicalnewstoday.com/releases/12516.php

Cannabis does not induce schizophrenia, Dutch scientists say (news - 2004)

http://www.medicalnewstoday.com/articles/12283.php

Symptoms of schizotypy precede cannabis use. (full - 2005)

http://socialsciences.people.hawaii.edu/publications_lib/Cannabis and SPD.pdf

Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol

vs. amisulpride in acute schizophrenia. (abst - 2005) http://www.cannabis- med.org/studies/ww_en_db_study_show.php?s_id=171
579

Cannabis and schizophrenia link blurs further (news - 2005)

http://www.newscientist.com/channel/health/mg18624953.800-cannabis-and-schizophrenia-link-blurs- further.html

Chemicals in Cannabis may help mentally ill (news - 2005)

http://www.news-medical.net/news/2005/06/06/10716.aspx

Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug.

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100- 879X2006000400001&lng=en&nrm=iso&tlng=en

The Mental Health Risks of Adolescent Cannabis Use (full - 2006)

(full - 2006)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1351917&tool=pmcentrez

Cannabis and psychosis (letter - 2006)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1360440&tool=pmcentrez

An Experimental Study of Catechol-O-Methyltransferase Val(158)Met Moderation of Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition.
(abst - 2006)

http://www.unboundmedicine.com/medline/ebm/record/16936704/abstract/An_Experimental_Study_of_Ca techol_O_Methyltransferase_Val_158_Met_Moderation_of_Delta_9_Tetrahydrocannabinol_Induced_Effe cts_on_Psychosis_and_Cognition

Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16710682

Cannabis use does not cause schizophrenia (news - 2006)

http://www.health.am/psy/more/cannabis_use_does_not_cause_schizophrenia/

No Increased Schizophrenia Risk With Use Of Cannabis (news - 2006)

http://www.thehempire.com/index.php/cannabis/news/no_increased_schizophrenia_risk_with_use_of_cann abis

Cannabis is a First-Line Treatment for Childhood Mental Disorders (news - 2006)
http://www.counterpunch.org/mikuriya07082006.html

Reefer Madness Refuted (letter - 2007) http://www.cmaj.ca/cgi/eletters/177/8/988#16873

A Comparison of Symptoms and Family History in Schizophrenia with and Without Prior Cannabis Use: Implications for the Concept of Cannabis Psychosis.
(abst – 2007)
http://www.schres-journal.com/article/S0920-9964(07)00150-8/abstract

Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: Impact of cannabis use. (abst - 2007) http://www.unboundmedicine.com/medline/ebm/record/17566707/abstract/Anandamide_levels_in_cerebro spinal_fluid_of_first_episode_schizophrenic_patients:_Impact_of_cannabis_use
580
 
Pages 581 - 585

Cannabinoids and psychosis. (abst - 2007)

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=1734986 5&ordinalpos=185&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis
(full - 2008) http://bjp.rcpsych.org/cgi/content/full/192/4/306?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=ca nnabinoid&searchid=1&FIRSTINDEX=1200&resourcetype=HWCIT

The effects of cannabis abuse on the symptoms of schizophrenia: patient perspectives. (abst – 2008) http://www.ncbi.nlm.nih.gov/pubmed/18666905

Maternal tobacco, cannabis and alcohol use during pregnancy and risk of adolescent psychotic symptoms in offspring. (full - 2009) http://bjp.rcpsych.org/cgi/content/full/195/4/294

Cannabis and suicide: longitudinal study. (full - 2009)

http://bjp.rcpsych.org/content/195/6/492.long

Parasitic brain infection, endocannabinoids, and schizophrenia. (abst - 2009)

http://www.unboundmedicine.com/medline/ebm/record/18995970/abstract/Parasitic_brain_infection_endoc annabinoids_and_schizophrenia_

The role of cannabis in cognitive functioning of patients with schizophrenia.
(abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19326102/abstract/The_role_of_cannabis_in_cogni tive_functioning_of_patients_with_schizophrenia_

Cannabis use and deliberate self-harm in adolescence: a comparative analysis of

associations in England and Norway.

(abst - 2009)

http://www.unboundmedicine.com/medline/ebm/record/19813111/abstract/Cannabis_use_and_deliberate_s elf_harm_in_adolescence:_a_comparative_analysis_of_associations_in_England_and_Norway_

Opposite relationships between cannabis use and neurocognitive functioning in bipolar disorder and schizophrenia. (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19891810/full_citation/Opposite_relationships_bet ween_cannabis_use_and_neurocognitive_functioning_in_bipolar_disorder_and_schizophrenia_

Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania (abst – 2009) http://jop.sagepub.com/content/25/2/274.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=c annabinoid&searchid=1&FIRSTINDEX=320&sortspec=date&resourcetype=HWCIT

Synthetic delta-9-tetrahydrocannabinol (dronabinol) can improve the symptoms of schizophrenia. (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19440079/abstract/Synthetic_delta_9_tetrahydroca nnabinol__dronabinol__can_improve_the_symptoms_of_schizophrenia_
581

Can recreational doses of THC produce significant dopamine release in the human striatum? (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19539765/full_citation/Can_recreational_doses_of _THC_produce_significant_dopamine_release_in_the_human_striatum

If cannabis caused schizophrenia-how many cannabis users may need to be prevented in order to prevent one case of schizophrenia? England and Wales calculations.
(abst - 2009)

http://www.unboundmedicine.com/medline/ebm/record/19832786/full_citation/If_cannabis_caused_schizo phrenia_how_many_cannabis_users_may_need_to_be_prevented_in_order_to_prevent_one_case_of_schiz ophrenia_England_and_Wales_calculations_

Minimal Relationship Between Cannabis And Schizophrenia Or Psychosis, Suggested By New Study (news - 2009) http://www.sciencedaily.com/releases/2009/10/091022101538.htm

Science: The development of the number of new schizophrenia cases in the UK does not support the hypothesis that cannabis use increases schizophrenia risk
(news – 2009) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=299#2

Schizophrenia link to cannabis denied (news - 2009)

http://www.thisisstaffordshire.co.uk/news/Schizophrenia-link-cannabis-denied/article-1288926- detail/article.html

New study suggests minimal relationship between cannabis and schizophrenia or psychosis (news – 2009) http://www.physorg.com/news175425054.html

THC can improve symptoms of schizophrenia (news – 2009)

http://www.cannabis-med.org/index.php?tpl=cannabinoids&id=233&lng=en&red=cannabinoidslist

Maternal Marijuana use not Associated with Psychotic Symptoms , but Alcohol is. (news - 2009) http://ohiopatientsnetwork.org/index.php?option=com_content&view=article&id=85:marijuana-not- associated-with-psychotic-symptoms-but-alcohol-is&catid=3:newsflash

Endocannabinoids and Schizophrenia (full – 2010)

http://www.mdpi.com/1424-8247/3/10/3101/pdf

Do patients think cannabis causes schizophrenia? - A qualitative study on the causal beliefs of cannabis using patients with schizophrenia (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954921/?tool=pmcentrez

Reasons for illicit drug use in people with schizophrenia: Qualitative study (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999587/?tool=pubmed

Are cannabis use disorders associated with an earlier age at onset of psychosis? A study

in first episode schizophrenia. (full – 2010)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900481/?tool=pubmed
582

Therapeutical use of the cannabinoids in psychiatry (full – 2010)

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516- 44462010000500009&lng=en&nrm=iso&tlng=en

A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055343/?tool=pubmed

Cannabinoid–Dopamine Interaction in the Pathophysiology and Treatment of CNS Disorders (full – 2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5949.2010.00144.x/full

Brain cannabinoid CB2 receptor in schizophrenia. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/19931854

A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice. (abst – 2010) http://www.unboundmedicine.com/medline/ebm/record/19785914/abstract/A_behavioural_comparison_of_ acute_and_chronic_Delta9_tetrahydrocannabinol_and_cannabidiol_in_C57BL/6JArc_mice_

Cannabinoid self-administration attenuates PCP-induced schizophrenia-like symptoms in adult rats. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19854030

Does intravenous {triangleup}9-tetrahydrocannabinol increase dopamine release? A SPET study. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed?term=20851843

The Impact of Cannabis Use on Cognitive Functioning in Patients With Schizophrenia: A Meta-analysis of Existing Findings and New Data in a First-Episode Sample.
(abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20660494

Attraction to cannabis among men with schizophrenia: a phenomenological study. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20420097

Tardive Dystonia and the Use of Cannabis (letter - 2010)

http://www.turkpsikiyatri.com/en/default.aspx?modul=article&id=749

Oral THC Reduces Aggressive Behavior In Patients With Refractory Psychosis, Study Says (news - 2010) http://www.norml.org/index.cfm?Group_ID=8419

Risk of suicide spurs rimonabant trial to end. (news – 2010)

http://www.thefreelibrary.com/Risk+of+suicide+spurs+rimonabant+trial+to+end.-a0238838571

Deletion of CB2 Cannabinoid Receptor Induces Schizophrenia-Related Behaviors in Mice (full – 2011) http://www.nature.com/npp/journal/v36/n7/full/npp201134a.html

Cannabis use predicts shorter duration of untreated psychosis and lower levels of

negative symptoms in first-episode psychosis: a South African study. (full – 2011)

http://www.ajop.co.za/Journals/November2010/Original articles/Cannabis use.pdf
583

Cannabinoids for the Treatment of Schizophrenia? A Balanced Neurochemical Framework for Both Adverse and Therapeutic Effects of Cannabis Use (full – 2011) http://www.hindawi.com/journals/sprt/2011/501726/

Psychopharmacological comparison of schizophrenia spectrum disorder with and without cannabis dependency. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21087649

Synthetic cannabinoid JWH-018 and psychosis: An explorative study. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21316162/abstract/Synthetic_cannabinoid_JWH_0 18_and_psychosis:_An_explorative_study_

Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. (abst – 2011) http://www.nature.com/neuro/journal/v14/n3/full/nn.2736.html

Endocannabinoid system dysfunction in mood and related disorders. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21916860

Cannabis with high cannabidiol content is associated with fewer psychotic experiences. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21592732

Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21798112

The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21887137

History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21890594

Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation? (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21926420

Deletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors in mice. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21430651

The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/20701826/abstract/The_schizophrenia_susceptibilit y_gene_neuregulin_1_modulates_tolerance_to_the_effects_of_cannabinoids_

Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/22007164/abstract/Endocannabinoid_system_and_ psychiatry:_in_search_of_a_neurobiological_basis_for_detrimental_and_potential_therapeutic_effects_
584

The endocannabinoid system in the regulation of emotions throughout lifespan: a discussion on therapeutic perspectives. (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21693551/abstract/The_endocannabinoid_system_i n_the_regulation_of_emotions_throughout_lifespan:_a_discussion_on_therapeutic_perspectives_

Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21513772/abstract/Association_between_a_cannab inoid_receptor_gene__CNR1__polymorphism_and_cannabinoid_induced_alterations_of_the_auditory_eve nt_related_P300_potential_

Marijuana Use Associated With 'Superior' Cognitive Performance In Schizophrenic Patients, Study Says (news – 2011) http://www.norml.org/index.cfm?Group_ID=8537

Omega-3 PUFA Deficiency Abolishes Endocannabinoid-Linked Neuronal Functions (news - 2011) http://www.fatsoflife.com/article.php?nid=1&edition=this&id=1837&issueid=85

A Brain Wrought Without Omega-3 (news – 2011)

http://www.schizophreniaforum.org/new/detail.asp?id=1646

Debunking the Myth of a Link Between Marijuana and Mental Illness

http://www.alternet.org/drugs/151776

The Link Between Marijuana and Schizophrenia (news – 2011)

http://www.time.com/time/health/article/0,8599,2005559,00.html

SCLERODERMA

(news – 2011)

The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757311/?tool=pmcentrez

The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis (full - 2009) http://www3.interscience.wiley.com/cgi-bin/fulltext/122290593/HTMLSTART

Cannabinoids inhibit fibrogenesis in diffuse systemic sclerosis fibroblasts (full - 2009)

http://rheumatology.oxfordjournals.org/content/48/9/1050.full

The cannabinoid WIN55, 212-2 abrogates dermal fibrosis in scleroderma bleomycin model. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21177293
585
 
Pages 586 - 590

Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20508030

SEPTIC SHOCK

Protection Against Septic Shock and Suppression of Tumor Necrosis Factor α and Nitric Oxide Production by Dexanabinol (HU-211), a Nonpsychotropic Cannabinoid
(full - 1997) http://jpet.aspetjournals.org/content/283/2/918.full

Presynaptic cannabinoid CB1 receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575049/?tool=pmcentrez

Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats (full – 2005) http://bja.oxfordjournals.org/content/94/5/563.full

Effects of AM281, a cannabinoid antagonist, on circulatory deterioration and cytokine production in an endotoxin shock model: comparison with norepinephrine. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/17072693

The cannabinoid receptor 2 is critical for the host response to sepsis. (full – 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763235/?tool=pubmed

Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005548/?tool=pubmed

Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20561509

Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034694/?tool=pmcentrez

The endocannabinoid system in sepsis – a potential target to improve microcirculation? (full – 2011) http://www.signavitae.com/articles/...endocannabinoid-system-in-sepsis-a-potential- target-to-improve-microcirculation
586

SICKLE CELL DISEASE


Cannabis use in sickle cell disease: a questionnaire study. (abst - 2005)

http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=16173972&dopt=Abstrac t

Medical use of cannabis in sickle cell disease (news - 2005)

http://www.chanvre-info.ch/info/it/Medical-use-of-cannabis-in-sickle.html

The prevalence of marijuana smoking in young adults with sickle cell disease: a longitudinal study (full - 2006) http://caribbean.scielo.org/scielo.php?script=sci_arttext&pid=S0043- 31442006000400004&lng=en&nrm=iso

Marijuana Use Prevalent Among Sickle Cell Patients news - 2007)

http://norml.org/index.cfm?Group_ID=7163

Marijuana Use and Sickle Cell Disease (abst - 2008)

http://abstracts.hematologylibrary.org/cgi/content/abstract/112/11/4826?maxtoshow=&hits=80&RESULTF ORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1840&resourcetype=HWCIT

Cannabinoids as Analgesics for Pain in Sickle Cell Disease. (abst - 2009)

http://abstracts.hematologylibrary.org/cgi/content/abstract/114/22/822?maxtoshow=&hits=80&RESULTF ORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT

New Era Dawns on Sickle Cell Pain (full - 2010)

http://bloodjournal.hematologylibrary.org/cgi/reprint/116/3/311

Pain related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids. (full - 2010) http://bloodjournal.hematologylibrary.org/content/116/3/456.long

Cannibinoids Offer Novel Treatment for Pain in Sickle Cell Disease, Study Suggests (news - 2010) http://www.sciencedaily.com/releases/2010/07/100722121225.htm

Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22171826

SINUSITIS

HEMP AS A MEDICAMENT : Cannabis indica in oto-rhino-laryngology (full - 1955)

https://www.greenpassion.org/index.php?/topic/23450-cannabis-indica-in-oto-rhino-laryngology/
587

SLEEPING SICKNESS/ TRYPANOSOMIASIS


The trypanocidal effect of Cannabis sativa constituents in experimental animal trypanosomiasis. (African Sleeping Sickness) (abst – 1994) http://www.ncbi.nlm.nih.gov/pubmed/7900270

SLEEP MODULATION

Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism (full - 1972) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1666020/

Therapeutic aspects of cannabis and cannabinoids. (full - 2001)

http://bjp.rcpsych.org/cgi/content/full/178/2/107

Functional role for cannabinoids in respiratory stability during sleep. (full - 2002)

http://science.iowamedicalmarijuana.org/pdfs/lungs/Carley 2002.pdf

The cannabinoids R(-)-7-hydroxy-delta-6-tetra-hydrocannabinol-dimethylheptyl (HU- 210), 2-O-arachidonoylglycerylether (HU-310) and arachidonyl-2-chloroethylamide (ACEA) increase isoflurane provoked sleep duration by activation of cannabinoids 1 (CB1)-receptors in mice. (abst – 2002) http://www.ncbi.nlm.nih.gov/pubmed/12095655

THC reduces sleep apnoea in animal research (news - 2002)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=120#1

Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/14746372?dopt=Abstract

Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early- morning behavior in young adults. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15118485?dopt=Abstract

Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial. (abst - 2004) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=15

Randomized, controlled trial of cannabis-based medicine in central pain in multiple
sclerosis. (abst - 2005)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=175
588

Cannabinoids attenuate norepinephrine-induced melatonin biosynthesis in the rat pineal gland by reducing arylalkylamine N-acetyltransferase activity without involvement of cannabinoid receptors. (full – 2006) http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.2006.03873.x/pdf

Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. (abst - 2006)

http://www.ncbi.nlm.nih.gov/pubmed/16844117

The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=177

Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex, a cannabis- based medicine. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17712817

Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep. (abst - 2007) http://marijuana.researchtoday.net/archive/4/8/1234.htm

Cannabinoids Associated With "More Restful Sleep," Study Says (news - 2007)

http://www.illinoisnorml.org/content/view/648/27/

Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18313952?dopt=AbstractPlus

The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent. (abst - 2008)

http://www.unboundmedicine.com/medline/ebm/record/19045957/abstract/The_nonpsychoactive_cannabis _constituent_cannabidiol_is_a_wake_inducing_agent_

The Effects of Nabilone on Sleep in Fibromyalgia: Results of a Randomized Controlled Trial. (full - 2009) http://www.anesthesia-analgesia.org/content/110/2/604.long

Smoked cannabis for chronic neuropathic pain: a randomized controlled trial (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950205/?tool=pmcentrez

Endocannabinoid signalling: has it got rhythm? (full – 2010)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931554/?tool=pubmed

The Maternal Lifestyle Study: Sleep Problems in Children with Prenatal Substance Exposure (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917192/?tool=pubmed

Sleep and Medicinal Cannabis (abst - 2010)

http://www.cmcr.ucsd.edu/index.php?option=com_content&view=article&id=151:sleep-and-medicinal- cannabis&catid=41:research-studies&Itemid=135

Study: Smoking pot may ease chronic pain (news - 2010)

http://www.cnn.com/2010/HEALTH/08/30/health.pot.reduce.pain/
589

Administration of URB597, oleoylethanolamide or palmitoylethanolamide increases waking and dopamine in rats. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136458/?tool=pubmed

Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21262236

A study on the endogenous cannabinoid system synthetic and catabolic enzyme levels in patients with obstructive sleep apnea. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21729625

Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21867717

Medical marijuana turns former soldier's life around (news – 2011)

http://www.examiner.com/cannabis-culture-in-phoenix/medical-marijuana-turns-former-soldier-s-life- around

Treat aleep apnea with medical marijuana (news – 2011)

http://www.examiner.com/holistic-health-in-boulder/treat-sleep-apnea-with-medical-marajuana

SMALLPOX (also see COW POX)

Cannabinoids lead to enhanced virulence of the smallpox vaccine (vaccinia) virus.
(abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21131094/abstract/Cannabinoids_lead_to_enhance d_virulence_of_the_smallpox_vaccine__vaccinia__virus_

SMELL / ODOR DETECTION

Marijuana Odor Perception (full – 2004)

http://www.cannabis-science.com/papers/Cannabis Smell Searches Paperfull.pdf

Cannabinoid action in the olfactory epithelium (full – 2007)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1815290/?tool=pubmed

The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis. (full – 2010) http://www.jneurosci.org/content/30/26/8965.long
590
 
Pages 591 - 595

Endocannabinoid modulation in the olfactory epithelium. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20865377

Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial
(full – 2011) http://annonc.oxfordjournals.org/content/early/2011/02/11/annonc.mdq727.full

Acute Immobilization Stress Modulate GABA Release from Rat Olfactory Bulb: Involvement of Endocannabinoids—Cannabinoids and Acute Stress Modulate GABA Release (full – 2011) http://www.hindawi.com/journals/ijcb/2011/529851/

Cannabinoid receptor-mediated regulation of neuronal activity in the main olfactory bulb (abst – 2011) http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/855.3?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype =HWCIT

SMOKED CANNABIS AS A MEDICATION

CANNABIS AND MARINOL IN THE TREATMENT OF MIGRAINE HEADACHE (full - no date) http://www.druglibrary.org/schaffer/hemp/migrn2.htm

Marihuana smoking and intraocular pressure. (abst - 1971)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=47

Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects (full - 1974) http://www.ukcia.org/research/SmokedAndOralInAsthmatic.php

Effects of smoked marijuana in experimentally induced asthma. (full - 1975)

http://www.ukcia.org/research/InducedAsthma/index.php

Anticonvulsant nature of marihuana smoking (abst - 1975)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=39

Short-term effects of smoked marihuana on left ventricular function in man (full - 1977)

http://chestjournal.chestpubs.org/content/72/1/20.full.pdf+html?maxtoshow=&hits=80&RESULTFORMA T=&fulltext=cannabis&searchid=1&FIRSTINDEX=640&resourcetype=HWCIT

Effect of marihuana on intraocular and blood pressure in glaucoma (full - 1980)

http://www.ukcia.org/research/EffectOnIntraocularAndBloodPressureInGlaucoma.php

Comparison of effects of marihuana cigarettes of three different potencies (full - 1982)

http://www.nature.com/clpt/journal/v31/n5/pdf/clpt198286a.pdf
591

Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy (full - 1988) http://www.medmjscience.org/Pages/science/pierson.html

Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory. (abst - 1988) http://www.cannabis- med.org/studies/ww_en_db_study_show.php?s_id=117

Marijuana Smoking: Factors That Influence the Bioavailability of Tetrahydrocannabinol (full - 1990) http://www.ukcia.org/research/FactorsThatInfluenceBioavailability.pdf

Effects of delta 9-THC on marijuana smoking, dose choice, and verbal report of drug liking. (full - 1994) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1334408/?tool=pubmed

The perceived effects of smoked cannabis on patients with multiple sclerosis. (abst - 1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=13

Marijuana Smoking vs Cannabinoids for Glaucoma Therapy (full - 1998)

http://archopht.ama-assn.org/cgi/content/full/116/11/1433

Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11509190?dopt=Abstract

Chronic Cannabis Use in the Compassionate Investigational New Drug Program (full - 2002) http://www.maps.org/mmj/russo2002.pdf

The Role of Cannabis and Cannabinoids in Pain Management (full – 2002)

http://www.humanhemphealth.ca/Russo-AAPM_chapter.pdf

A Dramatic Response to Inhaled Cannabis in a Woman with Central Thalamic Pain and Dystonia (full - 2002) http://www.jpsmjournal.com/article/PIIS0885392402004268/fulltext

Chronic Cannabis Use in the Compassionate Investigational New Drug Program (abstract & comments- 2002) http://www.letfreedomgrow.com/cmu/chronic_cannabis_use.htm

The effects of smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opiods. (abst - 2003)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=96

Study: Brain Not Permanently Damaged by Marijuana (news - 2003)

http://www.drugfree.org/join-together/drugs/study-brain-not-permanently

Marijuana Smoking Doesn't Kill (news - 2003)

http://www.webmd.com/smoking-cessation/news/20030918/marijuana-smoking-doesnt-kill

Epilepsy patients are smoking pot (news - 2004)

http://www.safeaccessnow.org/article.php?id=1638
592

Marinol vs Natural Cannabis (full - 2005)

http://www.norml.org/pdf_files/NORML_Marinol_vs_Natural_Cannabis.pdf

Smoked cannabis therapy for HIV-related painful peripheral neuropathy: results of a randomized, placebo-controlled clinical trial. (abst - 2005) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=172

Medical use of cannabis in sickle cell disease (news - 2005)

http://www.chanvre-info.ch/info/it/Medical-use-of-cannabis-in-sickle.html

Evaluation of herbal cannabis characteristics by medical users: a randomized trial (full - 2006) http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17101054

The Cannabinoid Cb1 Receptor Antagonist Rimonabant Attenuates the Hypotensive Effect of Smoked Marijuana in Male Smokers. (full – 2006) http://www.ahjonline.com/article/S0002-8703(05)01013-6/fulltext

Marijuana smoking in young adults with sickle cell (news - 2006)

http://www.illinoisnorml.org/content/view/309/

Single and multiple doses of rimonabant antagonize acute effects of smoked cannabis in male cannabis users. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689519/?tool=pubmed

Dose-dependent Effects of Smoked Cannabis on Capsaicin-Induced Pain and Hyperalgesia in Healthy Volunteers. (full - 2007) http://www.cmcr.ucsd.edu/geninfo/Wallace_2007.pdf

Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep. (abst - 2007)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=190

Fitness to drive in spite (because) of THC (abst - 2007)

http://www.unboundmedicine.com/medline/ebm/record/17879702/abstract/[Fitness_to_drive_in_spite_ _because__of_THC%5D

Study Supports Medical Marijuana Use (news - 2007)

http://www.drugfree.org/join-together/drugs/study-supports-medical

Smoked Cannabis Proven Effective In Treating Neuropathic Pain (news - 2007)

http://www.sciencedaily.com/releases/2007/10/071024141745.htm

Marijuana gives relief from chronic pain for AIDS sufferers (news - 2007)

http://www.news-medical.net/news/2007/02/14/21906.aspx

Smoked Cannabis Reduces Foot Pain Associated With HIV In Placebo Trial (news - 2007) http://www.sciencedaily.com/releases/2007/02/070212185335.htm
593

Hypothesizing that marijuana smokers are at a significantly lower risk of carcinogenicity

relative to tobacco-non-marijuana smokers: evidenced based on statistical reevaluation of

current literature. (full - 2008)

http://www.thefreelibrary.com/Hypothesizing+that+marijuana+smokers+are+at+a+significantly+lower...- a0196052086

A Randomized, Placebo Controlled Cross-Over Trial of Cannabis Cigarettes in Neuropathic Pain (full - 2008) http://www.cmcr.ucsd.edu/geninfo/Wilsey_2008.pdf

Medicinal Marijuana Effective For Neuropathic Pain In HIV, Study Finds (news - 2008) http://www.sciencedaily.com/releases/2008/08/080806113135.htm

Marijuana May Be Effective For Neuropathic Pain (news - 2008)

http://www.sciencedaily.com/releases/2008/06/080626150628.htm

Cluster attacks responsive to recreational cannabis and dronabinol. (abst - 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19220500

3.0 Dosing (abst - 2009)

http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/dosing-posologie-eng.php

Smoked cannabis for chronic neuropathic pain: a randomized controlled trial
(full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950205/?tool=pmcentrez

Cannabinoid receptor 1 binding activity and quantitative analysis of Cannabis sativa L. smoke and vapor. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20118579

The relationship between substance use and posttraumatic stress disorder in a methadone maintenance treatment program. (abst – 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=309

Efficacy and tolerability of high-dose dronabinol maintenance in HIV-positive marijuana smokers: a controlled laboratory study. (abst – 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=316

Medicinal Marijuana Strains (news – 2010)

http://www.thefreelibrary.com/Medicinal+Marijuana+Strains-a01074139322

Smoking cannabis relieves chronic pain (news – 2010)

http://www.independent.co.uk/life-style/health-and-families/smoking-cannabis-relieves-chronic-pain- 2067287.html

Cannabis Inhalation Associated With Spontaneous Tumor Regression (news - 2010)

http://blog.norml.org/2011/03/22/ca...ated-with-spontaneous-tumor-regression-study- says/

Study: Smoking pot may ease chronic pain (news - 2010)

http://www.cnn.com/2010/HEALTH/08/30/health.pot.reduce.pain/
594

Marijuana better than pharmaceuticals at treating chronic pain, improving mood (news - 2010) http://www.naturalnews.com/029662_marijuana_chronic_pain.html

Chronic Pain Improved by Cannabis Smoking (news – 2010)

http://news.softpedia.com/news/Chronic-Pain-Improved-by-Cannabis-Smoking-154254.shtml

Spontaneous regression of septum pellucidum/forniceal pilocytic astrocytomas-possible role of Cannabis inhalation. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21336992

Medical cannabis use in post-traumatic stress disorder: a naturalistic observational study. (abst – 2011) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=481

Inhaled Cannabis May Keep Brain Cancer in Remission (news – 2011)

http://www.freedomisgreen.com/inhaled-marijuana-may-keep-brain-cancer-in-remission/

SOCIAL ADJUSTMENT/ BEHAVIOR

MARIHUANA INTOXICATION (abst -1934)

http://ajp.psychiatryonline.org/cgi/content/abstract/91/2/303?maxtoshow=&hits=80&RESULTFORMAT= &fulltext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

MARIHUANA AND AGGRESSIVE CRIME (abst - 1946)

http://ajp.psychiatryonline.org/cgi/content/abstract/102/6/825?maxtoshow=&hits=80&RESULTFORMAT =&fulltext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Marihuana Use and Psychosocial Adaptation (abst - 1974)

http://archpsyc.ama- assn.org/cgi/content/abstract/31/5/713?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana& searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Ganja in Jamaica (book – 1976) http://www.cifas.us/cannabis/PDFs/OCRGanjainJamaica.pdf The Effect of Marijuana on Small Group Process. (abst – 1977)

http://medical-journals.healia.com/doc/612199/The-effect-of-marijuana-on-small-group-process

Delta9-tetrahydrocannabinol: antiaggressive effects in mice, rats, and squirrel monkeys (abst - 1978) http://www.sciencemag.org/cgi/content/abstract/199/4336/1459?maxtoshow=&hits=80&RESULTFORMA T=&fulltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT

Adolescent Marihuana Use: Role of Parents and Peers. (abst – 1976)

http://medical-journals.healia.com/doc/4726001/Adolescent-marihuana-use-role-of-parents-and-peers

Marihuana and mood in human volunteers. (abst – 1978)

http://www.ncbi.nlm.nih.gov/pubmed/674253
595
 
Pages 596 - 600

Long-term cannabis use: characteristics of users in an Australian rural area. (abst - 1998) http://www.ncbi.nlm.nih.gov/pubmed/9744119

Effects of THC on Behavioral Measures of Impulsivity in Humans (full - 2003)

http://www.nature.com/npp/journal/v28/n7/full/1300176a.html

Cannabis Use Not Linked with Psychosocial Harm (news - 2004)

http://www.entheology.org/edoto/anmviewer.asp?a=239

Using Marijuana in Adulthood: the Experience of a Sample of Users in Oklahoma City. (abst – 2005) http://medical-journals.healia.com/doc/16537332/Using-marijuana-in-adulthood-the-experience-of-a- sample-of-users-in-Oklahoma-City

Cannabis, motivation, and life satisfaction in an internet sample (full - 2006)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435998/?tool=pmcentrez

Negative consequences associated with dependence in daily cannabis users (full - 2007) http://www.substanceabusepolicy.com/content/2/1/3

Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco. (full - 2007) http://archpedi.ama-assn.org/cgi/content/full/161/11/1042

Marijuana use motives and social anxiety among marijuana-using young adults. (abst - 2007) http://marijuana.researchtoday.net/archive/4/8/1303.htm

Teens who use only cannabis appear to function better than those who also use tobacco (news - 2007) http://www.news-medical.net/news/2007/11/06/32262.aspx

Are Cigarettes More of a Drag on Teens than Marijuana? (news - 2007)

http://www.scientificamerican.com/article.cfm?id=are-cigarettes-more-of-a

Teens Who Smoke Marijuana But Not Tobacco Are Different From Other Teen Groups (news - 2007) http://www.sciencedaily.com/releases/2007/11/071105164453.htm

Cannabinoid Modulation of Amygdala Reactivity to Social Signals of Threat in Humans (full - 2008) http://www.jneurosci.org/cgi/content/full/28/10/2313?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Characteristics of Adolescents Who Use Cannabis But Not Tobacco (news - 2008)

http://forum.grasscity.com/showthread.php?p=11734799#post11734799

Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)- tetrahydrocannabinol in rats. (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/19393686
596

Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996668/?tool=pubmed

Uni-Morbid and Co-Occurring Marijuana and Tobacco Use: Examination of Concurrent Associations with Negative Mood States (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861285/?tool=pubmed

Cannabis and crime: findings from a longitudinal study. (abst - 2010)

http://www.unboundmedicine.com/medline/ebm/record/19839964/full_citation/Cannabis_and_crime:_findi ngs_from_a_longitudinal_study_

Drug-Intake Methods and Social Identity: The Use of Marijuana in Blunts Among Southeast Asian Adolescents and Emerging Adults. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193281/?tool=pubmed

The social contagion effect of marijuana use among adolescents. (full – 2011)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018468/?tool=pubmed

Racial differences in trajectories of heavy drinking and regular marijuana use from ages 13 to 24 among African-American and White males. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21908109

Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21307846

Profile of Psychoactive Substances Consumption in Workplace. (abst – 2011)

http://www.ncbi.nlm.nih.gov/pubmed/21635864

Alcohol and cannabis abuse/dependence symptoms and life satisfaction in young adulthood. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21733007

Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation? (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21926420

The association between early conduct problems and early marijuana use in college students. (abst – 2011) http://marijuana.researchtoday.net/archive/8/9/4850.htm

The Kids Are All Right, Even if Their Parents Grow Pot (news – 2011)

http://www.parentdish.com/2011/07/27/the-kids-are-all-right-even-if-their-parents-grow-pot/

SPASTICITY

How Cannabis Compares to other treatments (no date - 2008)

http://dcsafeaccess.org/medical/how-cannabis-compares-to-other-treatments/
597

The perceived effects of marijuana on spinal cord injured males.

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=138

Marihuana as a therapeutic agent for muscle spasm or spasticity.

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=53

(abst - 1974) (abst - 1980)
Treatment of human spasticity with delta 9-tetrahydrocannabinol.

(abst - 1981) Cannabis effect on spasticity in spinal cord injury. (abst - 1982)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=8 http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=113

Effect of Delta-9-THC on EMG Measurements in Human Spasticity

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=110

The effect of delta-9-THC on human spasticity. (abst - 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=154

(abst - 1986)
Delta-9-THC in the treatment of spasticity associated with multiple sclerosis. (abst - 1987)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=1

Effect of cannabinoids on spasticity and ataxia in multiple sclerosis. (abst - 1989)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=2

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial. (abst + 1st page - 1990) http://www.springerlink.com/content/3826667673770p51/fulltext.pdf?page=1

Nabilone in the treatment of multiple sclerosis. (abst - 1995)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=11

Treatment of spasticity in spinal cord injury with dronabinol, a tetrahydrocannabinol derivative. (abst - 1995) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=112

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients. (abst - 1996) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=12

Endocannabinoids control spasticity in a multiple sclerosis model (full - 2000)

http://www.fasebj.org/cgi/reprint/00- 0399fjev1?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cannabis&andorexactfulltext=and&sear chid=1&FIRSTINDEX=10&sortspec=relevance&resourcetype=HWCIT

Cannabinoids in the treatment of pain and spasticity in multiple sclerosis. (abst - 2002)

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=12137404&dopt=abstrac tplus
598

Experiences with THC-treatment in children and adolescents (abst - 2003)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=80

The treatment of spasticity with D9-tetrahydrocannabinol (D9-THC) in patients with spinal cord injury (abst - 2003) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=79

Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. (abst - 2004) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=56

Efficacy of tetrahydrocannabinol in patients refractory to standard antiemetic therapy.Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study. (abst - 2004) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=63

Are oral cannabinoids safe and effective in refractory neuropathic pain?

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=143

CB1 cannabinoid receptor-mediated modulation of food intake in mice

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576140/?tool=pmcentrez

(abst - 2004) (full - 2005)

Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up. (abst - 2005)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=160

Cannabis-based medicinal extract (Sativex) produced significant improvements in a subjective measure of spasticity which were maintained on long-term treatment with no evidence of tolerance. (abst - 2005) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=170

The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury. (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=166

Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : A double-blind placebo-controlled cross-over trial.
(abst - 2006)

http://www.unboundmedicine.com/medline/ebm/record/16988792/abstract/Low_dose_treatment_with_the_ synthetic_cannabinoid_Nabilone_significantly_reduces_spasticity_related_pain_:_A_double_blind_placeb o_controlled_cross_over_trial_

Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/17086911
599

Control of Spasticity in a Multiple Sclerosis Model is mediated by CB1, not CB2, Cannabinoid Receptors (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189718/?tool=pmcentrez

Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis (full - 2007) http://medicalcannabis.com/images/pdf09/indications/ms/collin_et_al_2007_sativex.pdf

Motor effects of delta 9 THC in cerebellar Lurcher mutant mice. (abst - 2007)

http://www.unboundmedicine.com/medline/ebm/record/17531329/abstract/Motor_effects_of_delta_9_THC _in_cerebellar_Lurcher_mutant_mice

Cannabinoids in the management of spasticity associated with multiple sclerosis (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626929/?tool=pmcentrez

Whole plant cannabis extracts in the treatment of spasticity in multiple sclerosis: a systematic review (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793241/

Marijuana Eases Spasticity in MS Patients (news – 2009)

http://www.webmd.com/multiple-sclerosis/news/20091204/marijuana-eases-spasticity-in-ms-patients

Marijuana Chemicals Ease MS Symptoms, Review Confirms (news - 2009)

http://www.drugfree.org/uncategorized/marijuana-chemicals-ease-ms

Cannabis can reduce spasticity in MS patients (news - 2009)

http://www.news-medical.net/news/20091204/Cannabis-can-reduce-spasticity-in-MS-patients.aspx

New approaches in the management of spasticity in multiple sclerosis patients: role of cannabinoids (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835560/?tool=pmcentrez

A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex(®) ), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis. (abst – 2011) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=322

Meta-analysis of the efficacy and safety of Sativex (nabiximols), on spasticity in people with multiple sclerosis (abst - 2010) http://msj.sagepub.com/cgi/content/abstract/16/6/707?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabis&searchid=1&FIRSTINDEX=0&sortspec=date&resourcetype=HWCIT

THC and CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis. (abst -2011) http://www.unboundmedicine.com/medline/ebm/record/21456949/abstract/THC_and_CBD_oromucosal_s pray__Sativex%C2%AE__in_the_management_of_spasticity_associated_with_multiple_sclerosis_

Cannabinoids in children (abst – 2011)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=295
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